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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for RBPJ

Z-value: 1.17

Motif logo

Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
ENSG00000168214.21 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RBPJhg38_v1_chr4_+_26320975_263210300.945.4e-04Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_100993409 1.75 ENST00000471714.6
ABI family member 3 binding protein
chr3_-_100993507 1.74 ENST00000284322.10
ABI family member 3 binding protein
chr7_+_94394886 1.14 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr14_-_52950992 1.10 ENST00000343279.8
ENST00000399304.7
ENST00000395631.6
ENST00000341590.8
fermitin family member 2
chr10_+_31319125 0.78 ENST00000320985.14
ENST00000560721.6
ENST00000558440.5
ENST00000424869.6
ENST00000542815.7
zinc finger E-box binding homeobox 1
chr3_+_69763726 0.63 ENST00000448226.9
melanocyte inducing transcription factor
chr2_-_144516154 0.63 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr2_-_144431001 0.62 ENST00000636413.1
zinc finger E-box binding homeobox 2
chr2_-_144516397 0.61 ENST00000638128.1
zinc finger E-box binding homeobox 2
chr2_-_144430934 0.61 ENST00000638087.1
ENST00000638007.1
zinc finger E-box binding homeobox 2
chr2_-_79087986 0.50 ENST00000305089.8
regenerating family member 1 beta
chr12_+_65279092 0.47 ENST00000646299.1
methionine sulfoxide reductase B3
chr10_+_122560639 0.45 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr1_-_85404494 0.44 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr20_+_44582549 0.44 ENST00000372886.6
cAMP-dependent protein kinase inhibitor gamma
chr5_-_124744513 0.44 ENST00000504926.5
zinc finger protein 608
chr12_+_65278919 0.43 ENST00000538045.5
ENST00000642411.1
ENST00000535239.5
ENST00000614640.4
methionine sulfoxide reductase B3
chr10_+_122560679 0.43 ENST00000657942.1
deleted in malignant brain tumors 1
chr10_+_122560751 0.41 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr9_-_101594995 0.39 ENST00000636434.1
protein phosphatase 3 regulatory subunit B, beta
chr10_-_37857582 0.38 ENST00000395867.8
ENST00000611278.4
zinc finger protein 248
chr10_-_37858037 0.35 ENST00000395873.7
ENST00000357328.8
ENST00000395874.2
zinc finger protein 248
chr3_+_69763549 0.34 ENST00000472437.5
melanocyte inducing transcription factor
chr12_+_65279445 0.33 ENST00000642404.1
methionine sulfoxide reductase B3
chr5_-_140564245 0.30 ENST00000412920.7
ENST00000511201.2
ENST00000354402.9
ENST00000356738.6
amyloid beta precursor protein binding family B member 3
chr5_-_88823763 0.29 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr5_-_88877967 0.28 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr2_+_109898685 0.28 ENST00000480744.2
LIM zinc finger domain containing 3
chr17_+_2796404 0.27 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chr12_+_6828377 0.26 ENST00000290510.10
prolyl 3-hydroxylase 3
chr10_-_33335074 0.26 ENST00000432372.6
neuropilin 1
chr12_+_12785652 0.25 ENST00000356591.5
apolipoprotein L domain containing 1
chr13_-_74133892 0.25 ENST00000377669.7
Kruppel like factor 12
chr10_-_33334898 0.25 ENST00000395995.5
neuropilin 1
chr10_-_33334625 0.23 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr7_-_120858066 0.22 ENST00000222747.8
tetraspanin 12
chr7_+_90709816 0.22 ENST00000436577.3
cyclin dependent kinase 14
chr5_+_141412979 0.22 ENST00000612503.1
ENST00000398610.3
protocadherin gamma subfamily A, 10
chr7_+_90709530 0.22 ENST00000406263.5
cyclin dependent kinase 14
chr9_-_137028878 0.21 ENST00000625103.1
ENST00000614293.4
ATP binding cassette subfamily A member 2
chr19_-_39204254 0.21 ENST00000318438.7
syncollin
chr14_-_52791597 0.21 ENST00000216410.8
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr11_+_118607598 0.20 ENST00000600882.6
ENST00000356063.9
pleckstrin homology like domain family B member 1
chr10_-_43648845 0.20 ENST00000374433.7
zinc finger protein 32
chr10_-_43648704 0.20 ENST00000395797.1
zinc finger protein 32
chr19_-_55597753 0.20 ENST00000587678.1
FLT3 interacting zinc finger 1
chr10_-_33334382 0.19 ENST00000374823.9
ENST00000374821.9
ENST00000374816.7
neuropilin 1
chr2_-_110473041 0.19 ENST00000632897.1
ENST00000413601.3
LIM zinc finger domain containing 4
chr7_+_90709231 0.19 ENST00000446790.5
ENST00000265741.7
cyclin dependent kinase 14
chr21_+_37420299 0.18 ENST00000455097.6
ENST00000643854.1
ENST00000645424.1
ENST00000642309.1
ENST00000645774.1
ENST00000398956.2
dual specificity tyrosine phosphorylation regulated kinase 1A
chr15_+_40405787 0.18 ENST00000610693.5
ENST00000479013.7
ENST00000487418.8
isovaleryl-CoA dehydrogenase
chr14_+_51489112 0.17 ENST00000356218.8
FERM domain containing 6
chr4_+_26319636 0.17 ENST00000342295.6
ENST00000506956.5
ENST00000512671.6
ENST00000345843.8
recombination signal binding protein for immunoglobulin kappa J region
chr1_+_61404076 0.16 ENST00000357977.5
nuclear factor I A
chr10_+_113679839 0.16 ENST00000369318.8
ENST00000369315.5
caspase 7
chr11_+_118607579 0.16 ENST00000530708.4
pleckstrin homology like domain family B member 1
chrX_+_106802660 0.16 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1 domain family member 8B
chr9_-_101594918 0.16 ENST00000374806.2
protein phosphatase 3 regulatory subunit B, beta
chr10_+_113679523 0.15 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr11_+_64285533 0.15 ENST00000538032.5
G protein-coupled receptor 137
chr19_-_50025936 0.15 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr6_+_33208488 0.15 ENST00000374656.5
ring finger protein 1
chr2_-_40430257 0.14 ENST00000408028.6
ENST00000332839.8
ENST00000406391.2
ENST00000405901.7
solute carrier family 8 member A1
chr11_-_119340544 0.14 ENST00000530681.2
C1q and TNF related 5
chr12_-_89656093 0.14 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr12_-_89656051 0.13 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr10_-_27242068 0.13 ENST00000375901.5
ENST00000412279.1
ENST00000676731.1
ENST00000679220.1
ENST00000678392.1
ENST00000678446.1
ENST00000677441.1
ENST00000375905.8
acyl-CoA binding domain containing 5
chr12_+_57772587 0.12 ENST00000300209.13
EEF1A lysine methyltransferase 3
chr3_-_100993448 0.12 ENST00000495063.6
ENST00000486770.7
ENST00000530539.2
ABI family member 3 binding protein
chr16_+_23302292 0.12 ENST00000343070.7
sodium channel epithelial 1 subunit beta
chr17_-_41481140 0.12 ENST00000246639.6
ENST00000393989.1
keratin 35
chr17_-_38735577 0.12 ENST00000610747.1
polycomb group ring finger 2
chr10_+_73168111 0.11 ENST00000242505.11
family with sequence similarity 149 member B1
chr1_-_180502536 0.11 ENST00000367595.4
acyl-CoA binding domain containing 6
chr11_-_124935973 0.11 ENST00000298251.5
hepatic and glial cell adhesion molecule
chr5_+_138179145 0.11 ENST00000508792.5
ENST00000504621.1
kinesin family member 20A
chr22_-_31489761 0.11 ENST00000344710.9
ENST00000330125.10
ENST00000397518.5
eukaryotic translation initiation factor 4E nuclear import factor 1
chr1_+_36224410 0.11 ENST00000469141.6
ENST00000648638.1
ENST00000354618.10
thyroid hormone receptor associated protein 3
chr8_+_67952028 0.11 ENST00000288368.5
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr7_+_74209947 0.11 ENST00000475494.5
ENST00000398475.5
linker for activation of T cells family member 2
chr10_+_111077021 0.11 ENST00000280155.4
adrenoceptor alpha 2A
chr1_-_197775435 0.10 ENST00000620048.6
DENN domain containing 1B
chr1_-_180502811 0.10 ENST00000642319.1
acyl-CoA binding domain containing 6
chr12_+_4809176 0.10 ENST00000280684.3
potassium voltage-gated channel subfamily A member 6
chr12_+_57772648 0.10 ENST00000333012.5
EEF1A lysine methyltransferase 3
chr11_+_64285472 0.10 ENST00000535675.5
ENST00000543383.5
G protein-coupled receptor 137
chr7_-_27130182 0.10 ENST00000511914.1
homeobox A4
chr3_-_45915698 0.10 ENST00000539217.5
leucine zipper transcription factor like 1
chr5_+_138179093 0.10 ENST00000394894.8
kinesin family member 20A
chr5_+_42423433 0.09 ENST00000230882.9
growth hormone receptor
chr10_-_48251757 0.09 ENST00000305531.3
FERM and PDZ domain containing 2
chr1_-_43389768 0.09 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chrX_+_38006551 0.09 ENST00000297875.7
synaptotagmin like 5
chr1_+_113390495 0.09 ENST00000307546.14
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr18_+_3451585 0.09 ENST00000551541.5
TGFB induced factor homeobox 1
chr14_-_24232332 0.09 ENST00000534348.5
ENST00000524927.1
ENST00000250495.10
NEDD8-MDP1 readthrough
NEDD8 ubiquitin like modifier
chr12_-_4649043 0.09 ENST00000545990.6
ENST00000228850.6
A-kinase anchoring protein 3
chr17_-_28726186 0.08 ENST00000292090.8
TLC domain containing 1
chr19_-_38899529 0.08 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr3_+_159852933 0.08 ENST00000482804.1
schwannomin interacting protein 1
chr1_+_151008412 0.08 ENST00000271620.8
ENST00000650332.1
ENST00000450884.5
ENST00000368937.5
ENST00000431193.5
ENST00000368936.5
prune exopolyphosphatase 1
chr15_+_67125707 0.08 ENST00000540846.6
SMAD family member 3
chr1_-_151008365 0.08 ENST00000361936.9
ENST00000361738.11
MINDY lysine 48 deubiquitinase 1
chr17_-_16215520 0.08 ENST00000582357.5
ENST00000436828.5
ENST00000268712.8
ENST00000411510.5
ENST00000395857.7
nuclear receptor corepressor 1
chr8_-_22232020 0.08 ENST00000454243.7
ENST00000321613.7
phytanoyl-CoA 2-hydroxylase interacting protein
chr4_+_26320975 0.08 ENST00000509158.6
ENST00000681856.1
ENST00000680140.1
ENST00000355476.8
ENST00000680511.1
recombination signal binding protein for immunoglobulin kappa J region
chr19_-_38899800 0.08 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr19_+_3094348 0.08 ENST00000078429.9
G protein subunit alpha 11
chr3_-_19934189 0.07 ENST00000295824.14
EF-hand domain family member B
chr16_-_70685791 0.07 ENST00000616026.4
MTSS I-BAR domain containing 2
chr19_+_36687579 0.07 ENST00000682579.1
ENST00000536254.6
zinc finger protein 567
chr1_+_151008513 0.07 ENST00000368935.1
prune exopolyphosphatase 1
chr16_-_1611985 0.07 ENST00000426508.7
intraflagellar transport 140
chr19_-_45584769 0.07 ENST00000263275.5
outer mitochondrial membrane lipid metabolism regulator OPA3
chr9_+_70043840 0.07 ENST00000377182.5
MAM domain containing 2
chr6_+_20403679 0.07 ENST00000535432.2
E2F transcription factor 3
chr1_-_999981 0.06 ENST00000484667.2
hes family bHLH transcription factor 4
chr20_+_33662310 0.06 ENST00000375222.4
chromosome 20 open reading frame 144
chr19_-_40218339 0.06 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr19_+_43596480 0.06 ENST00000533118.5
zinc finger protein 576
chr16_+_85611401 0.06 ENST00000405402.6
Gse1 coiled-coil protein
chr11_+_64285219 0.06 ENST00000377702.8
G protein-coupled receptor 137
chr11_-_64744811 0.06 ENST00000377497.7
ENST00000377487.5
ENST00000430645.1
RAS guanyl releasing protein 2
chr11_-_31817904 0.06 ENST00000423822.7
paired box 6
chr11_-_31817937 0.06 ENST00000638965.1
ENST00000241001.13
ENST00000638914.3
ENST00000379132.8
ENST00000379129.7
paired box 6
chr13_-_19782970 0.06 ENST00000427943.1
ENST00000619300.4
paraspeckle component 1
chr16_+_53703963 0.06 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO alpha-ketoglutarate dependent dioxygenase
chr15_+_74890005 0.06 ENST00000569931.5
ENST00000566377.5
ENST00000569233.5
ENST00000567132.5
ENST00000564633.5
ENST00000568907.5
ENST00000563422.5
ENST00000564003.5
ENST00000562800.5
ENST00000563786.5
ENST00000535694.5
ENST00000323744.10
ENST00000352410.9
ENST00000568828.5
ENST00000562606.5
ENST00000565576.5
ENST00000567570.5
mannose phosphate isomerase
chr7_+_100589573 0.05 ENST00000468962.5
ENST00000427939.2
F-box protein 24
chr3_-_184017863 0.05 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr7_-_120857124 0.05 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr8_-_100336184 0.05 ENST00000519527.5
ENST00000522369.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chrX_-_70260199 0.05 ENST00000374519.4
pyrimidinergic receptor P2Y4
chr16_+_75148478 0.05 ENST00000568079.5
ENST00000570010.6
ENST00000464850.5
ENST00000332307.4
ENST00000393430.6
ZFP1 zinc finger protein
chr9_-_95507416 0.05 ENST00000429896.6
patched 1
chr16_+_58025745 0.04 ENST00000219271.4
matrix metallopeptidase 15
chr19_-_45584810 0.04 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr16_+_30064142 0.04 ENST00000562168.5
ENST00000569545.5
aldolase, fructose-bisphosphate A
chr20_+_31637905 0.04 ENST00000376075.4
cytochrome c oxidase subunit 4I2
chr8_-_67062120 0.04 ENST00000357849.9
COP9 signalosome subunit 5
chr13_-_19782923 0.04 ENST00000338910.9
paraspeckle component 1
chr1_+_7961894 0.04 ENST00000377491.5
ENST00000377488.5
Parkinsonism associated deglycase
chr20_-_46308485 0.04 ENST00000537909.4
cadherin 22
chr17_+_43170452 0.04 ENST00000341165.10
ENST00000586650.5
NBR1 autophagy cargo receptor
chr4_+_26320782 0.04 ENST00000514807.5
ENST00000348160.9
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_91021996 0.04 ENST00000337393.10
zinc finger protein 644
chr4_+_26320563 0.04 ENST00000361572.10
recombination signal binding protein for immunoglobulin kappa J region
chr19_+_34926892 0.04 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
zinc finger protein 30
chr16_+_30064274 0.04 ENST00000563060.6
aldolase, fructose-bisphosphate A
chr12_+_10505602 0.04 ENST00000322446.3
eukaryotic translation initiation factor 2 subunit gamma B
chr4_+_70195719 0.04 ENST00000683306.1
odontogenic, ameloblast associated
chr6_-_75493773 0.03 ENST00000237172.12
filamin A interacting protein 1
chr5_-_138178599 0.03 ENST00000454473.5
ENST00000418329.5
ENST00000254900.10
ENST00000230901.9
ENST00000402931.5
ENST00000411594.6
ENST00000430331.1
bromodomain containing 8
chr12_-_31792290 0.03 ENST00000340398.5
H3.5 histone
chr1_-_197775298 0.03 ENST00000367396.7
DENN domain containing 1B
chr1_-_147172456 0.03 ENST00000254101.4
protein kinase AMP-activated non-catalytic subunit beta 2
chr11_-_64879675 0.03 ENST00000359393.6
ENST00000433803.1
ENST00000411683.1
EH domain containing 1
chr1_+_43389889 0.03 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr1_-_204166334 0.03 ENST00000272190.9
renin
chr1_+_50106265 0.03 ENST00000357083.8
ELAV like RNA binding protein 4
chr7_+_30771388 0.03 ENST00000265299.6
MINDY lysine 48 deubiquitinase 4
chr17_-_64662290 0.03 ENST00000262435.14
SMAD specific E3 ubiquitin protein ligase 2
chr2_+_186486246 0.03 ENST00000337859.11
zinc finger CCCH-type containing 15
chr18_+_13218195 0.03 ENST00000679167.1
low density lipoprotein receptor class A domain containing 4
chr11_-_119340816 0.03 ENST00000528368.3
C1q and TNF related 5
chr11_+_64285839 0.03 ENST00000438980.7
ENST00000540370.1
G protein-coupled receptor 137
chr3_+_156142962 0.03 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr2_+_149330506 0.03 ENST00000334166.9
LY6/PLAUR domain containing 6
chr6_-_26056460 0.03 ENST00000343677.4
H1.2 linker histone, cluster member
chr7_+_102912983 0.02 ENST00000339431.9
ENST00000249377.4
leucine rich repeat containing 17
chr11_-_64879709 0.02 ENST00000621096.4
EH domain containing 1
chr19_+_39997031 0.02 ENST00000599504.5
ENST00000596894.5
ENST00000601138.5
ENST00000347077.9
ENST00000600094.5
zinc finger protein 546
chr1_+_43389874 0.02 ENST00000372450.8
SZT2 subunit of KICSTOR complex
chr11_-_2270584 0.02 ENST00000331289.5
achaete-scute family bHLH transcription factor 2
chr1_+_109483905 0.02 ENST00000459635.2
ENST00000683729.1
ENST00000369870.7
ataxin 7 like 2
chr14_+_24232422 0.02 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
guanosine monophosphate reductase 2
chr2_+_169733811 0.02 ENST00000392647.7
kelch like family member 23
chr10_-_73167961 0.02 ENST00000372979.9
ecdysoneless cell cycle regulator
chr19_+_43596388 0.02 ENST00000391965.6
ENST00000525771.1
zinc finger protein 576
chr15_+_67065586 0.02 ENST00000327367.9
SMAD family member 3
chr11_-_67523396 0.02 ENST00000353903.9
ENST00000294288.5
calcium binding protein 2
chr6_-_32224060 0.02 ENST00000375023.3
notch receptor 4
chr4_+_155667654 0.02 ENST00000513574.1
guanylate cyclase 1 soluble subunit alpha 1
chr7_+_128862841 0.02 ENST00000249289.5
ENST00000492758.1
ATPase H+ transporting V1 subunit F
chr10_-_73168052 0.02 ENST00000430082.6
ENST00000454759.6
ENST00000413026.1
ENST00000453402.5
ecdysoneless cell cycle regulator
chr10_+_116545907 0.02 ENST00000369221.2
pancreatic lipase
chr19_+_19405655 0.01 ENST00000683918.1
GATA zinc finger domain containing 2A
chrX_-_49264668 0.01 ENST00000455775.7
ENST00000652559.1
ENST00000376207.10
ENST00000557224.6
ENST00000684155.1
ENST00000376199.7
forkhead box P3
chr7_-_151632330 0.01 ENST00000418337.6
protein kinase AMP-activated non-catalytic subunit gamma 2
chr11_-_64745331 0.01 ENST00000377489.5
ENST00000354024.7
RAS guanyl releasing protein 2
chr11_-_32430811 0.01 ENST00000379079.8
ENST00000530998.5
WT1 transcription factor
chr2_+_218959635 0.01 ENST00000302625.6
cyclin dependent kinase 5 regulatory subunit 2
chr15_-_52529050 0.01 ENST00000399231.7
myosin VA
chr16_-_53703883 0.01 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1 like
chr3_-_132037800 0.01 ENST00000617767.4
copine 4
chr1_-_23369813 0.01 ENST00000314011.9
zinc finger protein 436
chr13_+_39038347 0.01 ENST00000379599.6
ENST00000379600.8
NHL repeat containing 3
chr10_-_97445850 0.01 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
exosome component 1
chr12_-_7695752 0.01 ENST00000329913.4
growth differentiation factor 3
chr21_-_6499202 0.01 ENST00000619610.2
ENST00000610664.5
ENST00000639996.1
U2 small nuclear RNA auxiliary factor 1 like 5

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 0.9 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 1.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.2 GO:0030091 protein repair(GO:0030091)
0.1 0.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 1.1 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.6 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.2 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.3 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 1.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 1.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.0 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 3.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0097443 sorting endosome(GO:0097443)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0035375 zymogen binding(GO:0035375)
0.1 1.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 2.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0031696 alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 3.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 4.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis