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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for REL

Z-value: 1.25

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
ENSG00000162924.15 REL proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELhg38_v1_chr2_+_60881515_60881552,
hg38_v1_chr2_+_60881553_60881619
0.939.9e-04Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_23949847 2.42 ENST00000588004.1
laminin subunit alpha 3
chr18_+_23873000 1.92 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr6_+_137867241 1.38 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr6_+_137867414 1.37 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr12_-_57767057 1.11 ENST00000228606.9
cytochrome P450 family 27 subfamily B member 1
chr18_+_36297661 1.09 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr10_-_98268186 0.99 ENST00000260702.4
lysyl oxidase like 4
chr12_-_66678934 0.81 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
glutamate receptor interacting protein 1
chr1_-_209651291 0.78 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr1_+_200894892 0.76 ENST00000413687.3
innate immunity activator
chr20_+_45174894 0.73 ENST00000243924.4
peptidase inhibitor 3
chr17_-_58415628 0.65 ENST00000583753.5
ring finger protein 43
chr19_-_4338786 0.65 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr11_+_10455292 0.63 ENST00000396553.6
adenosine monophosphate deaminase 3
chr11_+_102317492 0.63 ENST00000673846.1
baculoviral IAP repeat containing 3
chr6_-_143511682 0.62 ENST00000002165.11
alpha-L-fucosidase 2
chr11_-_58578096 0.61 ENST00000528954.5
ENST00000528489.1
leupaxin
chr4_+_73869385 0.59 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr6_+_30882914 0.56 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
discoidin domain receptor tyrosine kinase 1
chr12_-_94616061 0.54 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr1_+_95117324 0.53 ENST00000370203.9
ENST00000456991.5
TLC domain containing 4
chr12_-_85836372 0.52 ENST00000361228.5
Ras association domain family member 9
chr1_-_9129085 0.49 ENST00000377411.5
G protein-coupled receptor 157
chr19_-_50968775 0.47 ENST00000391808.5
kallikrein related peptidase 6
chr2_+_162318884 0.46 ENST00000446271.5
ENST00000429691.6
grancalcin
chr19_-_50968125 0.43 ENST00000594641.1
kallikrein related peptidase 6
chr6_+_13924867 0.41 ENST00000544682.5
ENST00000420478.2
ring finger protein 182
chr16_+_27313879 0.41 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
interleukin 4 receptor
chr12_+_51238854 0.39 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr7_-_16804987 0.39 ENST00000401412.5
ENST00000419304.7
anterior gradient 2, protein disulphide isomerase family member
chr11_-_441964 0.39 ENST00000332826.7
anoctamin 9
chr12_-_122500520 0.37 ENST00000540586.1
ENST00000543897.5
zinc finger CCHC-type containing 8
chr2_-_162318475 0.36 ENST00000648433.1
interferon induced with helicase C domain 1
chr19_+_14031746 0.36 ENST00000263379.4
interleukin 27 receptor subunit alpha
chr1_-_204411804 0.36 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr9_+_128149447 0.36 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr14_+_23372809 0.35 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr2_+_219229783 0.35 ENST00000453432.5
ENST00000409849.5
ENST00000323348.10
ENST00000416565.1
ENST00000410034.7
ENST00000447157.5
ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
chr14_-_24188787 0.34 ENST00000625289.1
ENST00000354464.11
importin 4
chr7_-_82443715 0.34 ENST00000356253.9
ENST00000423588.1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr11_-_72781833 0.32 ENST00000535054.1
ENST00000545082.5
StAR related lipid transfer domain containing 10
chr11_-_72781858 0.32 ENST00000537947.5
StAR related lipid transfer domain containing 10
chr6_+_14117764 0.32 ENST00000379153.4
CD83 molecule
chr12_-_54981838 0.31 ENST00000316577.12
thymocyte expressed, positive selection associated 1
chr9_-_133129395 0.30 ENST00000393157.8
ral guanine nucleotide dissociation stimulator
chr10_+_102395693 0.29 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
nuclear factor kappa B subunit 2
chr4_-_74099187 0.29 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr6_+_32154131 0.29 ENST00000375143.6
ENST00000324816.11
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr9_-_115118145 0.28 ENST00000350763.9
tenascin C
chr1_-_32901330 0.28 ENST00000329151.5
ENST00000373463.8
transmembrane protein 54
chr17_-_4739866 0.28 ENST00000574412.6
ENST00000293778.12
C-X-C motif chemokine ligand 16
chr9_-_115118198 0.28 ENST00000534839.1
ENST00000535648.5
tenascin C
chr11_+_102317542 0.28 ENST00000532808.5
baculoviral IAP repeat containing 3
chr11_+_72114840 0.28 ENST00000622388.4
folate receptor gamma
chr6_+_32154010 0.27 ENST00000375137.6
palmitoyl-protein thioesterase 2
chr2_+_60881515 0.26 ENST00000295025.12
REL proto-oncogene, NF-kB subunit
chr7_-_19145306 0.26 ENST00000275461.3
Fer3 like bHLH transcription factor
chr10_-_107164692 0.25 ENST00000263054.11
sortilin related VPS10 domain containing receptor 1
chr13_+_79481468 0.25 ENST00000620924.1
Nedd4 family interacting protein 2
chr11_+_102317450 0.24 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr20_+_44355692 0.24 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr1_+_6206077 0.24 ENST00000377939.5
ring finger protein 207
chr10_-_94362925 0.24 ENST00000371361.3
NOC3 like DNA replication regulator
chr13_+_79481446 0.24 ENST00000487865.5
Nedd4 family interacting protein 2
chr14_+_67619911 0.24 ENST00000261783.4
arginase 2
chr2_+_60881553 0.24 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chr6_-_29559724 0.23 ENST00000377050.5
ubiquitin D
chr4_-_73998669 0.22 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr1_-_155990062 0.22 ENST00000462460.6
Rho/Rac guanine nucleotide exchange factor 2
chr12_-_117099384 0.22 ENST00000335209.12
tescalcin
chr12_-_117099434 0.22 ENST00000541210.5
tescalcin
chr9_-_34637800 0.21 ENST00000680730.1
ENST00000477726.1
sigma non-opioid intracellular receptor 1
chr19_+_40717091 0.21 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr14_+_102777555 0.21 ENST00000539721.5
ENST00000560463.5
TNF receptor associated factor 3
chr10_+_102394488 0.21 ENST00000369966.8
nuclear factor kappa B subunit 2
chr2_-_88947820 0.20 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr14_-_68979436 0.20 ENST00000193403.10
actinin alpha 1
chr14_+_103123452 0.20 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr6_+_150721073 0.20 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr1_+_18630839 0.20 ENST00000420770.7
paired box 7
chr6_-_31582415 0.19 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr16_-_75464655 0.19 ENST00000569276.1
ENST00000357613.8
ENST00000561878.2
ENST00000566980.1
ENST00000567194.5
transmembrane protein 170A
novel TMEM170A-CFDP1 readthrough protein
chr12_+_11649666 0.19 ENST00000396373.9
ETS variant transcription factor 6
chr13_-_51453015 0.19 ENST00000442263.4
ENST00000311234.9
integrator complex subunit 6
chr4_-_74038681 0.19 ENST00000296026.4
C-X-C motif chemokine ligand 3
chrX_-_40735476 0.19 ENST00000324817.6
mediator complex subunit 14
chr2_+_90038848 0.19 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr21_-_41953997 0.19 ENST00000380486.4
C2 calcium dependent domain containing 2
chr1_+_156147350 0.18 ENST00000435124.5
ENST00000633494.1
semaphorin 4A
chr7_-_99144053 0.17 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr2_-_219229309 0.17 ENST00000443140.5
ENST00000432520.5
ENST00000409618.5
autophagy related 9A
chr2_-_74441882 0.17 ENST00000272430.10
rhotekin
chr15_+_41838839 0.17 ENST00000458483.4
phospholipase A2 group IVB
chr3_-_53046031 0.17 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr16_-_75464364 0.17 ENST00000569540.5
ENST00000566594.1
transmembrane protein 170A
novel TMEM170A-CFDP1 readthrough protein
chr2_-_219229571 0.17 ENST00000436856.5
ENST00000428226.5
ENST00000409422.5
ENST00000361242.9
ENST00000431715.5
ENST00000457841.5
ENST00000439812.5
ENST00000396761.6
autophagy related 9A
chr2_-_162318613 0.17 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr12_-_122500947 0.17 ENST00000672018.1
zinc finger CCHC-type containing 8
chr12_-_122500924 0.17 ENST00000633063.3
zinc finger CCHC-type containing 8
chr1_-_155991198 0.16 ENST00000673475.1
Rho/Rac guanine nucleotide exchange factor 2
chr12_+_57216779 0.16 ENST00000349394.6
neurexophilin 4
chr12_+_55818033 0.16 ENST00000552672.5
ENST00000243045.10
ENST00000550836.1
ORMDL sphingolipid biosynthesis regulator 2
chr6_+_135181268 0.16 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr19_+_38899946 0.16 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKB inhibitor beta
chr3_+_184249621 0.16 ENST00000324557.9
ENST00000402825.7
EEF1A lysine methyltransferase 4
EEF1AKMT4-ECE2 readthrough
chr19_-_45768843 0.15 ENST00000560168.1
SIX homeobox 5
chr11_-_105023136 0.15 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr5_-_150412743 0.15 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74 molecule
chr2_-_74465162 0.15 ENST00000649854.1
ENST00000650523.1
ENST00000649601.1
ENST00000448666.7
ENST00000409065.5
ENST00000414701.1
ENST00000452063.7
ENST00000649075.1
ENST00000648810.1
ENST00000462443.2
mannosyl-oligosaccharide glucosidase
chr18_-_46964408 0.15 ENST00000676383.1
elongin A3 family member D
chr3_-_49104745 0.15 ENST00000635194.1
ENST00000306125.12
ENST00000634602.1
ENST00000414533.5
ENST00000635443.1
ENST00000452739.5
ENST00000635231.1
glutaminyl-tRNA synthetase 1
chr2_+_15940537 0.14 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr22_-_33572227 0.14 ENST00000674780.1
LARGE xylosyl- and glucuronyltransferase 1
chr3_-_184249520 0.14 ENST00000455059.5
ENST00000445626.6
ALG3 alpha-1,3- mannosyltransferase
chr19_+_8209320 0.14 ENST00000561053.5
ENST00000559450.5
ENST00000251363.10
ENST00000559336.5
ceramide synthase 4
chr2_+_90114838 0.14 ENST00000417279.3
immunoglobulin kappa variable 3D-15
chr12_+_6946468 0.14 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr20_-_45348414 0.14 ENST00000372733.3
syndecan 4
chr11_-_72752376 0.14 ENST00000393609.8
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr22_-_37984534 0.13 ENST00000396884.8
SRY-box transcription factor 10
chr14_+_77181780 0.13 ENST00000298351.5
ENST00000554346.5
transmembrane protein 63C
chr19_-_48746797 0.13 ENST00000602105.1
ENST00000332955.7
izumo sperm-egg fusion 1
chr5_+_177086867 0.13 ENST00000503708.5
ENST00000393648.6
ENST00000514472.1
ENST00000502906.5
ENST00000292408.9
ENST00000510911.5
fibroblast growth factor receptor 4
chr15_-_73368951 0.13 ENST00000261917.4
hyperpolarization activated cyclic nucleotide gated potassium channel 4
chr14_+_102777461 0.13 ENST00000560371.5
ENST00000347662.8
TNF receptor associated factor 3
chr11_-_66546021 0.13 ENST00000310442.5
zinc finger DHHC-type containing 24
chr7_+_156949704 0.12 ENST00000275820.4
nucleolar protein with MIF4G domain 1
chr19_+_4229502 0.12 ENST00000221847.6
Epstein-Barr virus induced 3
chr19_+_38899680 0.12 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr3_-_52897541 0.12 ENST00000355083.11
ENST00000504329.1
STIM activating enhancer
STIMATE-MUSTN1 readthrough
chr9_-_133479075 0.12 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
solute carrier family 2 member 6
chr4_-_76036060 0.12 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr19_+_33373694 0.12 ENST00000284000.9
CCAAT enhancer binding protein gamma
chr1_+_63367619 0.12 ENST00000263440.6
ALG6 alpha-1,3-glucosyltransferase
chr14_-_68979314 0.12 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
actinin alpha 1
chr4_+_73836667 0.12 ENST00000226317.10
C-X-C motif chemokine ligand 6
chr3_-_49104457 0.12 ENST00000635292.1
ENST00000635541.1
ENST00000464962.6
glutaminyl-tRNA synthetase 1
chr3_+_47803125 0.11 ENST00000445061.6
ENST00000348968.8
DExH-box helicase 30
chr16_+_84175933 0.11 ENST00000569735.1
dynein axonemal assembly factor 1
chr10_-_73808616 0.11 ENST00000299641.8
N-deacetylase and N-sulfotransferase 2
chrX_+_153642473 0.11 ENST00000370167.8
dual specificity phosphatase 9
chr17_+_51260520 0.11 ENST00000225298.12
UTP18 small subunit processome component
chr1_+_202010575 0.11 ENST00000367283.7
ENST00000367284.10
E74 like ETS transcription factor 3
chr14_+_102777433 0.11 ENST00000392745.8
TNF receptor associated factor 3
chr3_+_101561833 0.11 ENST00000309922.7
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr4_-_55546900 0.11 ENST00000513440.6
clock circadian regulator
chr2_-_113235443 0.11 ENST00000465084.1
paired box 8
chr22_-_27919199 0.11 ENST00000634017.1
ENST00000436663.1
ENST00000320996.14
ENST00000335272.10
ENST00000455418.7
phosphatidylinositol transfer protein beta
chr6_+_10694916 0.11 ENST00000379568.4
PAK1 interacting protein 1
chr6_-_142946312 0.11 ENST00000367604.6
HIVEP zinc finger 2
chr9_-_136304084 0.10 ENST00000638797.2
ENST00000624277.3
coiled-coil domain containing 187
chr16_-_2196575 0.10 ENST00000343516.8
CASK interacting protein 1
chr2_+_218880844 0.10 ENST00000258411.8
Wnt family member 10A
chr7_+_69599588 0.10 ENST00000403018.3
activator of transcription and developmental regulator AUTS2
chr3_+_169911566 0.10 ENST00000428432.6
ENST00000335556.7
sterile alpha motif domain containing 7
chr2_-_68467272 0.10 ENST00000377957.4
F-box protein 48
chr16_+_67537439 0.09 ENST00000428437.6
ENST00000569253.5
RHO family interacting cell polarization regulator 1
chr20_-_37527862 0.09 ENST00000373537.7
ENST00000445723.5
ENST00000414080.1
BLCAP apoptosis inducing factor
chr3_+_101561926 0.09 ENST00000495642.1
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr10_+_104641282 0.09 ENST00000369701.8
sortilin related VPS10 domain containing receptor 3
chr16_+_68843515 0.09 ENST00000261778.2
transport and golgi organization 6 homolog
chr1_-_61725121 0.09 ENST00000371177.2
ENST00000606498.5
TM2 domain containing 1
chr5_+_50667405 0.09 ENST00000505554.5
poly(ADP-ribose) polymerase family member 8
chr14_+_37197904 0.09 ENST00000556615.5
ENST00000396294.6
mirror-image polydactyly 1
chr14_+_37197921 0.09 ENST00000684589.1
ENST00000327441.11
mirror-image polydactyly 1
chr2_+_108377947 0.09 ENST00000272452.7
sulfotransferase family 1C member 4
chr4_-_184474518 0.08 ENST00000393593.8
interferon regulatory factor 2
chr14_+_37197988 0.08 ENST00000539062.6
mirror-image polydactyly 1
chr11_+_119168188 0.08 ENST00000454811.5
ENST00000409265.8
ENST00000449394.5
NLR family member X1
chr12_-_39619782 0.08 ENST00000308666.4
ATP binding cassette subfamily D member 2
chr2_+_201182873 0.08 ENST00000360132.7
caspase 10
chr4_+_113292925 0.08 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr20_-_37527723 0.08 ENST00000397135.1
ENST00000397137.5
BLCAP apoptosis inducing factor
chr2_-_28870266 0.08 ENST00000306108.10
tRNA methyltransferase 61B
chr3_+_101827982 0.08 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr15_+_85380625 0.08 ENST00000560302.5
A-kinase anchoring protein 13
chr5_+_96936071 0.08 ENST00000231368.10
leucyl and cystinyl aminopeptidase
chrX_+_116436599 0.08 ENST00000598581.3
solute carrier family 6 member 14
chr9_+_6328363 0.07 ENST00000344545.6
ENST00000381428.1
ENST00000314556.4
TPD52 like 3
chr4_+_113292838 0.07 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr2_+_201183120 0.07 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
caspase 10
chr4_+_72031902 0.07 ENST00000344413.6
ENST00000308744.12
neuropeptide FF receptor 2
chr16_+_50696999 0.07 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr13_-_98577131 0.07 ENST00000397517.6
serine/threonine kinase 24
chr22_+_46335699 0.07 ENST00000645190.1
ENST00000642562.1
ENST00000381019.3
tRNA mitochondrial 2-thiouridylase
chr21_+_33266350 0.07 ENST00000290200.7
interleukin 10 receptor subunit beta
chr10_+_30434176 0.07 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr14_+_37198025 0.07 ENST00000556451.5
ENST00000556753.5
mirror-image polydactyly 1
chr19_+_3721719 0.07 ENST00000589378.5
tight junction protein 3
chr16_+_84176067 0.07 ENST00000564928.1
dynein axonemal assembly factor 1
chr15_+_76059973 0.07 ENST00000388942.8
transmembrane protein 266
chr20_-_37527891 0.07 ENST00000414542.6
BLCAP apoptosis inducing factor
chr4_-_145180496 0.07 ENST00000447906.8
OTU deubiquitinase 4
chr16_+_24256313 0.06 ENST00000005284.4
calcium voltage-gated channel auxiliary subunit gamma 3
chr11_-_65614195 0.06 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr3_+_9890567 0.06 ENST00000489724.2
jagunal homolog 1
chr1_+_202416826 0.06 ENST00000466968.1
protein phosphatase 1 regulatory subunit 12B
chr2_-_18560616 0.06 ENST00000381249.4
retinol dehydrogenase 14
chr10_+_35605337 0.06 ENST00000321660.2
gap junction protein delta 4
chr11_-_128522189 0.06 ENST00000526145.6
ETS proto-oncogene 1, transcription factor

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.4 1.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.2 0.6 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.2 5.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.5 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.4 GO:1990834 response to odorant(GO:1990834)
0.1 0.4 GO:2001226 negative regulation of anion channel activity(GO:0010360) negative regulation of chloride transport(GO:2001226)
0.1 0.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.2 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.4 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.2 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964)
0.1 0.2 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.6 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0009624 response to nematode(GO:0009624)
0.0 0.6 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.9 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.4 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.5 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.7 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.4 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.2 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:0015884 folic acid transport(GO:0015884)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0055091 ornithine metabolic process(GO:0006591) phospholipid homeostasis(GO:0055091)
0.0 0.2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 1.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.0 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.8 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 5.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events