Project
avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Navigation
Downloads
Results for RHOXF1
Z-value: 1.41
Motif logo
Transcription factors associated with RHOXF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RHOXF1 | hg38_v1_chrX_-_120115909_120115916 | -0.42 | 3.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_91153149 Show fit | 1.52 |
ENST00000550758.1
|
decorin |
|
| chr1_+_163068775 Show fit | 1.49 |
ENST00000421743.6
|
regulator of G protein signaling 4 |
|
| chr13_+_101452629 Show fit | 1.29 |
ENST00000622834.4
ENST00000545560.6 ENST00000376180.8 |
integrin subunit beta like 1 |
|
| chr13_+_101452569 Show fit | 1.24 |
ENST00000618057.4
|
integrin subunit beta like 1 |
|
| chr13_+_101489940 Show fit | 1.20 |
ENST00000376162.7
|
integrin subunit beta like 1 |
|
| chr8_-_13514821 Show fit | 1.07 |
ENST00000276297.9
|
DLC1 Rho GTPase activating protein |
|
| chr5_-_111976925 Show fit | 1.04 |
ENST00000395634.7
|
neuronal regeneration related protein |
|
| chr12_-_91146195 Show fit | 0.93 |
ENST00000548218.1
|
decorin |
|
| chrX_+_153494970 Show fit | 0.85 |
ENST00000331595.9
ENST00000431891.1 |
biglycan |
|
| chr10_-_77140757 Show fit | 0.84 |
ENST00000637862.2
|
potassium calcium-activated channel subfamily M alpha 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of RHOXF1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 1.6 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.1 | 1.5 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.1 | 1.1 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 1.1 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.0 | 1.1 | GO:0034695 | response to prostaglandin E(GO:0034695) |
| 0.1 | 1.0 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.0 | 1.0 | GO:0051923 | sulfation(GO:0051923) |
| 0.2 | 0.8 | GO:0060301 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.1 | 0.8 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 2.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 2.4 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 1.6 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 1.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.0 | 1.0 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 0.9 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 0.8 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.0 | 0.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 0.6 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 1.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 1.6 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.1 | 1.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 1.4 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 1.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 0.8 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.1 | 0.8 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.0 | 0.8 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.8 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.3 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 1.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.0 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 0.9 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.7 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 2.6 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 2.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.1 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 1.0 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 1.0 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 1.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 0.9 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.8 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.8 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |