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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SIX4

Z-value: 0.12

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Transcription factors associated with SIX4

Gene Symbol Gene ID Gene Info
ENSG00000100625.9 SIX homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX4hg38_v1_chr14_-_60724300_60724362-0.482.3e-01Click!

Activity profile of SIX4 motif

Sorted Z-values of SIX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_10021490 0.11 ENST00000264784.8
solute carrier family 2 member 9
chr1_+_13585453 0.10 ENST00000487038.5
ENST00000475043.5
podoplanin
chr12_+_8822610 0.10 ENST00000299698.12
alpha-2-macroglobulin like 1
chr1_+_152514474 0.09 ENST00000368790.4
cysteine rich C-terminal 1
chr1_-_31798755 0.06 ENST00000452755.6
SPOC domain containing 1
chr1_-_183590876 0.06 ENST00000367536.5
neutrophil cytosolic factor 2
chr11_+_118077009 0.06 ENST00000616579.4
ENST00000534111.5
transmembrane serine protease 4
chr3_+_119147375 0.05 ENST00000490594.2
novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr14_+_21042352 0.05 ENST00000298690.5
ribonuclease A family member 7
chr19_-_474880 0.05 ENST00000382696.7
ENST00000315489.5
outer dense fiber of sperm tails 3 like 2
chr11_+_118077067 0.05 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
transmembrane serine protease 4
chr17_-_59707404 0.04 ENST00000393038.3
peptidyl-tRNA hydrolase 2
chr3_-_168095344 0.04 ENST00000309027.4
golgi integral membrane protein 4
chr1_+_115641945 0.04 ENST00000355485.7
ENST00000369510.8
VANGL planar cell polarity protein 1
chr16_+_590200 0.04 ENST00000563109.1
RAB40C, member RAS oncogene family
chr8_+_143716318 0.04 ENST00000338033.9
ENST00000395107.8
ENST00000395108.2
mitogen-activated protein kinase 15
chr3_-_184248935 0.04 ENST00000446569.1
ENST00000397676.8
ALG3 alpha-1,3- mannosyltransferase
chr5_-_1294989 0.04 ENST00000334602.10
ENST00000310581.10
telomerase reverse transcriptase
chr3_-_184249520 0.03 ENST00000455059.5
ENST00000445626.6
ALG3 alpha-1,3- mannosyltransferase
chr6_+_52186373 0.03 ENST00000648244.1
interleukin 17A
chr14_-_94517844 0.03 ENST00000341228.2
serpin family A member 12
chrY_+_20575716 0.03 ENST00000361365.7
eukaryotic translation initiation factor 1A Y-linked
chr13_+_113122791 0.03 ENST00000375559.8
ENST00000409306.5
ENST00000375551.7
coagulation factor X
chr17_+_40287861 0.03 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr17_-_41528293 0.03 ENST00000455635.1
ENST00000361566.7
keratin 19
chr11_+_64241053 0.03 ENST00000309366.9
ENST00000449942.6
ENST00000652762.2
FKBP prolyl isomerase 2
novel protein
chr1_+_231338242 0.03 ENST00000008440.9
ENST00000295050.12
SprT-like N-terminal domain
chr3_+_184249621 0.02 ENST00000324557.9
ENST00000402825.7
EEF1A lysine methyltransferase 4
EEF1AKMT4-ECE2 readthrough
chr11_+_7251886 0.02 ENST00000318881.11
synaptotagmin 9
chr17_-_63446260 0.02 ENST00000448884.6
ENST00000582297.5
ENST00000360793.8
ENST00000582034.5
ENST00000578072.1
cytochrome b561
chr11_-_5343524 0.02 ENST00000300773.3
olfactory receptor family 51 subfamily B member 5
chr13_-_113864062 0.02 ENST00000327773.7
growth arrest specific 6
chr1_-_231337830 0.02 ENST00000366645.1
exocyst complex component 8
chrY_+_20575792 0.02 ENST00000382772.3
eukaryotic translation initiation factor 1A Y-linked
chr7_+_69599588 0.02 ENST00000403018.3
activator of transcription and developmental regulator AUTS2
chr9_-_34895722 0.02 ENST00000603640.6
ENST00000603592.1
ENST00000340783.11
family with sequence similarity 205 member C
chr22_+_41833079 0.02 ENST00000612482.4
ENST00000361204.9
sterol regulatory element binding transcription factor 2
chr1_+_116373233 0.02 ENST00000295598.10
ATPase Na+/K+ transporting subunit alpha 1
chr1_-_37595927 0.02 ENST00000373062.8
G protein nucleolar 2
chr5_+_79069754 0.02 ENST00000518666.5
ENST00000521567.1
ENST00000255192.8
betaine--homocysteine S-methyltransferase 2
chr12_-_10130082 0.01 ENST00000533022.5
C-type lectin domain containing 7A
chr8_+_131904071 0.01 ENST00000254624.10
ENST00000522709.5
EFR3 homolog A
chr10_+_86654541 0.01 ENST00000241891.10
ENST00000372071.6
opsin 4
chr12_-_4379712 0.01 ENST00000237837.2
fibroblast growth factor 23
chr7_+_97732046 0.01 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chr11_-_113773668 0.01 ENST00000200135.8
zw10 kinetochore protein
chr1_+_26410809 0.01 ENST00000254231.4
ENST00000326279.11
lin-28 homolog A
chr19_+_50384323 0.01 ENST00000599857.7
ENST00000613923.6
ENST00000601098.6
ENST00000440232.7
ENST00000595904.6
ENST00000593887.1
DNA polymerase delta 1, catalytic subunit
chr3_+_32685128 0.01 ENST00000331889.10
ENST00000328834.9
CCR4-NOT transcription complex subunit 10
chr9_-_133209227 0.01 ENST00000372032.3
ENST00000372034.8
ENST00000618116.4
odorant binding protein 2B
chr7_-_113919000 0.01 ENST00000284601.4
protein phosphatase 1 regulatory subunit 3A
chr1_-_42335189 0.01 ENST00000361776.5
ENST00000445886.5
ENST00000361346.6
forkhead box J3
chr2_-_113241683 0.01 ENST00000468980.3
paired box 8
chr13_-_48001305 0.01 ENST00000643023.1
succinate-CoA ligase ADP-forming subunit beta
chr20_+_836052 0.01 ENST00000246100.3
family with sequence similarity 110 member A
chr14_-_106803221 0.01 ENST00000390636.2
immunoglobulin heavy variable 3-73
chrX_+_30235894 0.01 ENST00000620842.1
MAGE family member B3
chr19_-_46625037 0.01 ENST00000596260.1
ENST00000594275.1
ENST00000597185.1
ENST00000598865.5
ENST00000291294.7
prostaglandin I2 receptor
chrX_+_41724174 0.01 ENST00000302548.5
G protein-coupled receptor 82
chr1_-_42335869 0.01 ENST00000372573.5
forkhead box J3
chr10_+_10798570 0.01 ENST00000638035.1
ENST00000636488.1
CUGBP Elav-like family member 2
chr13_-_48001265 0.01 ENST00000646932.1
ENST00000433022.1
ENST00000470760.2
ENST00000644338.1
ENST00000646602.1
succinate-CoA ligase ADP-forming subunit beta
chr3_-_168095885 0.01 ENST00000470487.6
golgi integral membrane protein 4
chr19_+_19063986 0.01 ENST00000318596.8
solute carrier family 25 member 42
chr6_-_75363003 0.01 ENST00000370020.1
filamin A interacting protein 1
chr15_+_58987652 0.01 ENST00000348370.9
ENST00000559160.1
ring finger protein 111
chr1_-_37947010 0.01 ENST00000458109.6
ENST00000373024.8
ENST00000373023.6
inositol polyphosphate-5-phosphatase B
chr2_-_74482914 0.01 ENST00000290418.4
ENST00000393965.8
coiled-coil domain containing 142
chr1_+_156642148 0.01 ENST00000361588.5
brevican
chr17_+_7561899 0.01 ENST00000321337.12
SUMO specific peptidase 3
chr11_-_46593948 0.01 ENST00000533727.5
ENST00000534300.5
ENST00000683756.1
ENST00000528950.1
ENST00000526606.1
autophagy and beclin 1 regulator 1
chr2_+_74483067 0.01 ENST00000233623.11
ENST00000442235.6
ENST00000410003.5
tetratricopeptide repeat domain 31
chr20_-_44521989 0.01 ENST00000342374.5
ENST00000255175.5
serine incorporator 3
chr15_+_40953463 0.01 ENST00000617768.5
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr3_-_87276462 0.01 ENST00000561167.5
ENST00000560656.1
POU class 1 homeobox 1
chr11_+_125592826 0.01 ENST00000529196.5
ENST00000392708.9
ENST00000649491.1
ENST00000531491.5
STT3 oligosaccharyltransferase complex catalytic subunit A
chr3_-_87276577 0.00 ENST00000344265.8
ENST00000350375.7
POU class 1 homeobox 1
chr17_+_50561010 0.00 ENST00000360761.8
ENST00000354983.8
ENST00000352832.9
calcium voltage-gated channel subunit alpha1 G
chr6_-_27872334 0.00 ENST00000616365.2
H3 clustered histone 11
chr1_+_156642108 0.00 ENST00000457777.6
ENST00000329117.10
ENST00000424639.5
brevican
chr6_+_41072939 0.00 ENST00000341376.11
ENST00000353205.5
nuclear transcription factor Y subunit alpha
chr2_-_179562576 0.00 ENST00000336917.9
zinc finger protein 385B
chr12_-_10130241 0.00 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr12_-_10130143 0.00 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr3_-_122993232 0.00 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
semaphorin 5B
chr15_-_21742799 0.00 ENST00000622410.2
novel protein, identical to IGHV4-4
chr11_-_130314575 0.00 ENST00000397753.5
zinc finger and BTB domain containing 44
chr3_-_49120785 0.00 ENST00000417901.5
ENST00000306026.5
ENST00000434032.6
ubiquitin specific peptidase 19
chr11_+_119067774 0.00 ENST00000621676.5
ENST00000614944.4
VPS11 core subunit of CORVET and HOPS complexes
chr1_-_247172002 0.00 ENST00000491356.5
ENST00000472531.5
ENST00000340684.10
ENST00000543802.3
zinc finger protein 124
chrX_-_120629936 0.00 ENST00000371313.2
ENST00000304661.6
C1GALT1 specific chaperone 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)