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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SIX5_SMARCC2_HCFC1

Z-value: 1.90

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
ENSG00000177045.10 SIX homeobox 5
ENSG00000139613.12 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
ENSG00000172534.14 host cell factor C1

Activity-expression correlation:

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_64063481 5.80 ENST00000415602.5
transcription elongation factor A2
chr20_+_64063105 4.95 ENST00000395053.7
ENST00000343484.10
ENST00000339217.8
transcription elongation factor A2
chr1_+_47333863 3.25 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr22_-_29766934 3.17 ENST00000344318.4
zinc finger matrin-type 5
chr2_-_231781268 3.04 ENST00000287600.9
ENST00000409772.5
phosphodiesterase 6D
chr11_-_83071819 3.00 ENST00000524635.1
ENST00000526205.5
ENST00000533486.5
ENST00000533276.6
ENST00000527633.6
RAB30, member RAS oncogene family
chr3_+_69739425 2.99 ENST00000352241.9
ENST00000642352.1
melanocyte inducing transcription factor
chr19_+_49527988 2.88 ENST00000270645.8
reticulocalbin 3
chr16_-_3023932 2.79 ENST00000248089.8
ENST00000574151.5
host cell factor C1 regulator 1
chr14_-_65102339 2.78 ENST00000555419.5
MYC associated factor X
chr16_-_3024230 2.72 ENST00000572355.5
ENST00000574980.5
ENST00000354679.3
ENST00000573842.1
host cell factor C1 regulator 1
chr14_-_65102383 2.56 ENST00000341653.6
MYC associated factor X
chr1_+_156054761 2.53 ENST00000368305.9
ENST00000368304.9
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr11_-_73598183 2.43 ENST00000064778.8
family with sequence similarity 168 member A
chr11_-_74398378 2.38 ENST00000298198.5
phosphoglucomutase 2 like 1
chr14_-_73027117 2.38 ENST00000318876.9
zinc finger FYVE-type containing 1
chr14_-_73027077 2.35 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr16_-_636253 2.28 ENST00000565163.5
methyltransferase like 26
chr10_-_43648704 2.16 ENST00000395797.1
zinc finger protein 32
chr10_-_43648845 2.15 ENST00000374433.7
zinc finger protein 32
chr19_+_37078411 2.12 ENST00000337995.4
ENST00000304239.11
ENST00000589245.5
zinc finger protein 420
chr7_-_151057848 2.10 ENST00000297518.4
cyclin dependent kinase 5
chr12_-_53727428 2.08 ENST00000548263.5
ENST00000430117.6
ENST00000549173.5
ENST00000550804.6
ENST00000551900.5
ENST00000546619.5
ENST00000548177.5
ENST00000549349.5
calcium binding and coiled-coil domain 1
chr12_-_53727476 2.03 ENST00000549784.5
ENST00000262059.8
calcium binding and coiled-coil domain 1
chr19_+_44113385 2.03 ENST00000262894.11
ENST00000588926.5
ENST00000592780.5
zinc finger protein 225
chr11_-_73598067 1.99 ENST00000450446.6
ENST00000356467.5
family with sequence similarity 168 member A
chr7_-_151057880 1.96 ENST00000485972.6
cyclin dependent kinase 5
chr11_-_134253248 1.96 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
thymocyte nuclear protein 1
chr22_+_29767351 1.94 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_-_156741124 1.94 ENST00000368211.8
mitochondrial ribosomal protein L24
chr1_-_156741067 1.86 ENST00000361531.6
ENST00000412846.5
mitochondrial ribosomal protein L24
chr12_-_132956280 1.86 ENST00000536932.5
ENST00000360187.9
ENST00000392321.3
checkpoint with forkhead and ring finger domains
zinc finger protein 605
chr11_-_83285965 1.84 ENST00000529073.5
ENST00000529611.5
coiled-coil domain containing 90B
chr19_+_17420029 1.83 ENST00000317040.12
ENST00000529939.5
ENST00000528515.5
ENST00000543795.5
multivesicular body subunit 12A
chr11_+_72080595 1.83 ENST00000647530.1
ENST00000539271.6
ENST00000642510.1
leucine rich transmembrane and O-methyltransferase domain containing
chr16_-_636230 1.82 ENST00000568773.1
methyltransferase like 26
chr11_-_83071917 1.81 ENST00000534141.5
RAB30, member RAS oncogene family
chr10_+_110225955 1.81 ENST00000239007.11
MAX interactor 1, dimerization protein
chr16_-_636270 1.79 ENST00000397665.6
ENST00000397666.6
ENST00000301686.13
ENST00000338401.8
ENST00000397664.8
ENST00000568830.1
ENST00000614890.4
methyltransferase like 26
chr10_+_102854251 1.79 ENST00000339834.10
ENST00000369883.3
BLOC-1 related complex subunit 7
chr11_+_72080803 1.73 ENST00000423494.6
ENST00000539587.6
ENST00000536917.2
ENST00000538478.5
ENST00000324866.11
ENST00000643715.1
ENST00000439209.5
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr15_+_55408479 1.73 ENST00000569691.2
chromosome 15 open reading frame 65
chr12_+_106774630 1.70 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr16_-_15055969 1.69 ENST00000566419.1
ENST00000568320.5
N-terminal asparagine amidase
chr16_-_15056060 1.69 ENST00000287706.8
ENST00000624579.3
ENST00000622833.4
N-terminal asparagine amidase
chr8_-_38468601 1.68 ENST00000341462.9
ENST00000683765.1
ENST00000356207.9
ENST00000326324.10
ENST00000335922.9
ENST00000532791.5
fibroblast growth factor receptor 1
chr16_-_4538819 1.68 ENST00000564828.5
cell death inducing p53 target 1
chr11_-_83286328 1.65 ENST00000525503.5
coiled-coil domain containing 90B
chr14_-_77457554 1.63 ENST00000343765.6
ENST00000327028.8
ENST00000556412.4
ENST00000557466.1
ENST00000448935.6
ENST00000557658.6
ENST00000553888.5
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr8_-_38468627 1.63 ENST00000683815.1
ENST00000684654.1
ENST00000447712.7
ENST00000397091.9
fibroblast growth factor receptor 1
chr19_-_44356664 1.62 ENST00000354340.9
ENST00000337401.8
ENST00000587909.1
zinc finger protein 112
chr19_+_44165127 1.61 ENST00000590089.5
ENST00000454662.6
zinc finger protein 226
chr20_+_33811287 1.61 ENST00000217402.3
charged multivesicular body protein 4B
chr11_+_72080313 1.60 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr15_-_40807450 1.58 ENST00000220496.9
ENST00000627802.1
DnaJ heat shock protein family (Hsp40) member C17
chr2_+_201451711 1.58 ENST00000194530.8
ENST00000392249.6
STE20 related adaptor beta
chr19_-_6604083 1.54 ENST00000597430.2
CD70 molecule
chr11_-_78188588 1.53 ENST00000526208.5
ENST00000529350.1
ENST00000530018.5
ENST00000528776.1
ENST00000340067.4
potassium channel tetramerization domain containing 21
chr11_-_83286377 1.50 ENST00000455220.6
ENST00000529689.5
coiled-coil domain containing 90B
chr2_-_85418421 1.50 ENST00000409275.1
capping actin protein, gelsolin like
chr14_-_65102468 1.49 ENST00000555932.5
ENST00000284165.10
ENST00000358402.8
ENST00000246163.2
ENST00000358664.9
ENST00000556979.5
ENST00000555667.5
ENST00000557746.5
ENST00000556443.5
ENST00000618858.4
ENST00000557277.5
ENST00000556892.5
MYC associated factor X
chrX_-_64976435 1.49 ENST00000374839.8
zinc finger C4H2-type containing
chr12_+_12611839 1.48 ENST00000228865.3
cAMP responsive element binding protein like 2
chrX_-_64976500 1.47 ENST00000447788.6
zinc finger C4H2-type containing
chr10_-_37976589 1.46 ENST00000302609.8
zinc finger protein 25
chr4_+_2963580 1.43 ENST00000398051.8
ENST00000503518.2
G protein-coupled receptor kinase 4
chr4_-_8158689 1.42 ENST00000505872.5
ENST00000341937.9
ENST00000361581.9
ENST00000407564.7
ENST00000361737.9
ENST00000447017.7
ENST00000428004.6
actin binding LIM protein family member 2
chr17_-_18682262 1.42 ENST00000454745.2
ENST00000395675.7
forkhead box O3B
chr19_-_36489553 1.41 ENST00000392170.7
zinc finger protein 566
chr9_+_101398841 1.41 ENST00000339664.7
ENST00000374861.7
ENST00000259395.4
ENST00000615466.1
zinc finger protein 189
chrX_-_108091520 1.41 ENST00000340200.5
ENST00000217958.8
ENST00000372296.5
ENST00000372295.5
ENST00000361815.9
proteasome 26S subunit, non-ATPase 10
chr19_-_36489435 1.41 ENST00000434377.6
ENST00000424129.7
ENST00000452939.6
ENST00000427002.2
zinc finger protein 566
chr17_-_28335421 1.41 ENST00000578122.5
ENST00000579419.5
ENST00000585313.5
ENST00000578985.5
ENST00000577498.1
ENST00000585089.5
ENST00000357896.7
ENST00000395418.8
ENST00000588477.5
intraflagellar transport 20
chr6_-_41735557 1.40 ENST00000373033.6
transcription factor EB
chr19_+_37371092 1.38 ENST00000436120.7
zinc finger protein 527
chr5_+_179023794 1.37 ENST00000519896.5
ENST00000522442.1
ENST00000444149.7
zinc finger protein 879
chr1_-_25906457 1.36 ENST00000426559.6
stathmin 1
chr19_-_38899529 1.35 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr7_-_101245056 1.31 ENST00000223136.5
fission, mitochondrial 1
chr16_+_3024000 1.30 ENST00000326266.13
ENST00000574549.5
ENST00000575576.5
ENST00000253952.9
THO complex 6
chr20_-_50115935 1.29 ENST00000340309.7
ENST00000415862.6
ENST00000371677.7
ubiquitin conjugating enzyme E2 V1
chr16_-_4538761 1.29 ENST00000567695.6
ENST00000562334.5
ENST00000562579.5
ENST00000563507.5
cell death inducing p53 target 1
chr8_+_109334317 1.27 ENST00000521662.5
ENST00000520147.5
ENST00000521688.6
ENY2 transcription and export complex 2 subunit
chr16_-_4538469 1.27 ENST00000588381.1
ENST00000563332.6
cell death inducing p53 target 1
chr19_-_38899800 1.27 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr7_-_101245032 1.27 ENST00000442303.1
fission, mitochondrial 1
chr19_-_54115626 1.26 ENST00000391759.6
TCF3 fusion partner
chr19_-_50511203 1.25 ENST00000595669.5
Josephin domain containing 2
chr5_-_172006567 1.25 ENST00000517395.6
ENST00000265094.9
ENST00000393802.6
F-box and WD repeat domain containing 11
chr19_-_54115271 1.24 ENST00000391757.1
TCF3 fusion partner
chr10_+_122374685 1.22 ENST00000368990.7
ENST00000368989.6
ENST00000463663.6
pleckstrin homology domain containing A1
chr19_-_37467185 1.21 ENST00000592490.5
ENST00000392149.6
zinc finger protein 569
chr19_-_50025936 1.21 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr19_-_37467380 1.21 ENST00000316950.11
ENST00000591710.5
zinc finger protein 569
chr19_-_36489854 1.19 ENST00000493391.6
zinc finger protein 566
chr17_-_39927549 1.19 ENST00000579695.5
ENST00000304046.7
ORMDL sphingolipid biosynthesis regulator 3
chr11_+_134253531 1.19 ENST00000374752.6
ENST00000281182.9
acyl-CoA dehydrogenase family member 8
chr7_+_33129530 1.18 ENST00000671890.1
ENST00000350941.7
ENST00000396127.6
ENST00000355070.6
ENST00000671871.1
ENST00000673431.1
ENST00000671963.1
ENST00000242067.11
Bardet-Biedl syndrome 9
chr5_-_178730651 1.18 ENST00000335815.7
zinc finger protein 354A
chr1_-_54053192 1.17 ENST00000371337.3
ENST00000234831.10
transmembrane protein 59
chr19_-_5680488 1.14 ENST00000587589.1
ENST00000309324.9
mitochondrial contact site and cristae organizing system subunit 13
chr5_+_176388731 1.14 ENST00000274787.3
HIG1 hypoxia inducible domain family member 2A
chr12_+_133080875 1.14 ENST00000412146.6
ENST00000544426.5
ENST00000355557.7
ENST00000319849.7
ENST00000440550.6
zinc finger protein 140
chr1_+_244653081 1.13 ENST00000263831.11
ENST00000302550.16
desumoylating isopeptidase 2
chr1_+_202348687 1.13 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr19_+_507487 1.13 ENST00000359315.6
tubulin polyglutamylase complex subunit 1
chr5_-_172006817 1.12 ENST00000296933.10
F-box and WD repeat domain containing 11
chr14_-_91946989 1.12 ENST00000556154.5
fibulin 5
chr19_-_18919348 1.11 ENST00000349893.8
ENST00000351079.8
ENST00000600932.5
ENST00000262812.9
COPI coat complex subunit epsilon
chr19_+_54102838 1.10 ENST00000391762.5
ENST00000471292.5
ENST00000485876.6
ENST00000391763.3
ENST00000391764.7
ENST00000303553.5
NADH:ubiquinone oxidoreductase subunit A3
chr12_+_56152579 1.10 ENST00000551834.5
ENST00000552568.5
myosin light chain 6B
chr12_+_56152439 1.09 ENST00000550443.5
myosin light chain 6B
chr19_+_4304588 1.09 ENST00000221856.11
fibronectin type III and SPRY domain containing 1
chr3_+_184174846 1.08 ENST00000427072.5
ENST00000411763.6
ENST00000292807.9
ENST00000448139.5
ENST00000455925.1
adaptor related protein complex 2 subunit mu 1
chr15_+_63189554 1.07 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr14_-_24232332 1.06 ENST00000534348.5
ENST00000524927.1
ENST00000250495.10
NEDD8-MDP1 readthrough
NEDD8 ubiquitin like modifier
chr20_-_18497218 1.06 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr19_+_34734155 1.06 ENST00000599244.5
ENST00000392232.7
ENST00000492450.3
ENST00000595708.5
ENST00000593781.5
zinc finger protein 181
chr15_-_55408245 1.05 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr19_-_50511146 1.03 ENST00000594350.1
ENST00000601423.5
Josephin domain containing 2
chr2_-_201451446 1.03 ENST00000332624.8
ENST00000430254.1
trafficking kinesin protein 2
chr19_+_4304632 1.03 ENST00000597590.5
fibronectin type III and SPRY domain containing 1
chr5_-_40755885 1.03 ENST00000636863.1
ENST00000637375.1
ENST00000337702.5
ENST00000636106.1
tetratricopeptide repeat domain 33
chr17_-_45060988 1.03 ENST00000342350.9
dephospho-CoA kinase domain containing
chr5_-_139439488 1.02 ENST00000302060.10
DnaJ heat shock protein family (Hsp40) member C18
chr6_-_110815152 1.02 ENST00000413605.6
cyclin dependent kinase 19
chr19_+_44025326 1.01 ENST00000587846.5
ENST00000187879.12
ENST00000391960.4
zinc finger protein 222
chr19_-_50511173 1.01 ENST00000598418.6
Josephin domain containing 2
chr4_+_158672266 1.01 ENST00000684622.1
ENST00000683483.1
ENST00000684641.1
ENST00000682456.1
ENST00000684627.1
ENST00000511912.6
ENST00000684505.1
ENST00000683305.1
ENST00000684036.1
ENST00000683751.1
ENST00000684129.1
ENST00000307738.5
electron transfer flavoprotein dehydrogenase
chr6_-_27473058 1.01 ENST00000683788.1
ENST00000211936.10
zinc finger protein 184
chr11_+_114439515 1.01 ENST00000539119.5
RNA exonuclease 2
chr19_-_44304968 1.00 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
zinc finger protein 235
chr20_+_47501929 0.99 ENST00000371997.3
nuclear receptor coactivator 3
chr4_+_158672237 0.97 ENST00000682734.1
electron transfer flavoprotein dehydrogenase
chr19_+_34677639 0.97 ENST00000627982.2
ENST00000613363.4
ENST00000502743.5
ENST00000509528.5
ENST00000506901.5
ENST00000457781.6
ENST00000505163.5
ENST00000505242.6
ENST00000423823.6
ENST00000507959.5
ENST00000446502.6
zinc finger protein 302
chr19_+_37469337 0.97 ENST00000330173.6
zinc finger protein 570
chr1_+_149899561 0.96 ENST00000369152.6
bolA family member 1
chr19_+_44212525 0.95 ENST00000391961.6
ENST00000621083.4
ENST00000313040.12
ENST00000586228.5
ENST00000588219.5
ENST00000589707.5
ENST00000588394.5
ENST00000589005.5
zinc finger protein 227
chr2_+_135741717 0.94 ENST00000415164.5
UBX domain protein 4
chr11_+_86302211 0.93 ENST00000533986.5
ENST00000278483.8
heat shock protein nuclear import factor hikeshi
chr19_-_43935234 0.93 ENST00000269973.10
zinc finger protein 45
chr2_-_241508318 0.93 ENST00000439101.5
ENST00000424537.5
ENST00000401869.5
ENST00000436402.5
serine/threonine kinase 25
chr21_+_7744971 0.92 ENST00000622934.3
ENST00000619874.4
ENST00000612624.4
ENST00000624304.3
ENST00000624758.3
small integral membrane protein 11B
chr19_+_43984167 0.91 ENST00000611002.4
ENST00000270014.7
ENST00000591532.5
ENST00000407951.6
ENST00000590615.5
ENST00000586454.1
zinc finger protein 155
chr3_-_49429252 0.91 ENST00000615713.4
nicolin 1
chr5_-_132777866 0.91 ENST00000448933.5
septin 8
chr19_+_37218174 0.91 ENST00000590503.5
ENST00000684119.1
ENST00000589413.5
zinc finger protein 383
chr19_+_58305319 0.91 ENST00000413518.5
ENST00000427361.5
ENST00000610038.5
ENST00000608070.5
ENST00000609864.5
endogenous retrovirus group K3 member 1
chr19_+_34677723 0.91 ENST00000505365.2
zinc finger protein 302
chr9_+_69820827 0.90 ENST00000527647.5
ENST00000480564.1
chromosome 9 open reading frame 135
chr6_-_110815408 0.90 ENST00000368911.8
cyclin dependent kinase 19
chr5_-_65624288 0.90 ENST00000381018.7
ENST00000274327.11
ENST00000231524.14
tripartite motif containing 23
chrX_+_106802660 0.90 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1 domain family member 8B
chr19_-_13906062 0.89 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr17_-_45061092 0.89 ENST00000310604.8
dephospho-CoA kinase domain containing
chr6_+_109095110 0.88 ENST00000521277.5
ENST00000407272.5
ENST00000519286.5
centrosomal protein 57 like 1
chr19_+_44259875 0.87 ENST00000592581.5
ENST00000590668.5
ENST00000683810.1
zinc finger protein 233
chr5_-_132777404 0.87 ENST00000296873.11
septin 8
chr1_+_47333774 0.87 ENST00000371873.10
cytidine/uridine monophosphate kinase 1
chr11_+_36594369 0.86 ENST00000678060.1
ENST00000446510.6
ENST00000676979.1
ENST00000677808.1
ENST00000617650.5
ENST00000334307.10
ENST00000531554.6
ENST00000679022.1
ENST00000347206.8
ENST00000534635.5
ENST00000676921.1
ENST00000678950.1
ENST00000530697.6
ENST00000527108.6
ENST00000532470.3
intraflagellar transport associated protein
chr10_-_43574555 0.86 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
zinc finger protein 239
chr19_-_5680220 0.86 ENST00000587950.5
mitochondrial contact site and cristae organizing system subunit 13
chr8_+_144104943 0.86 ENST00000532522.5
ENST00000527572.5
ENST00000527058.1
MAF1 homolog, negative regulator of RNA polymerase III
chr5_-_132777344 0.86 ENST00000378706.5
septin 8
chr5_-_132777371 0.84 ENST00000620483.4
septin 8
chrX_-_72572794 0.84 ENST00000421523.6
ENST00000648036.1
ENST00000373559.8
ENST00000648139.1
ENST00000650636.1
ENST00000648962.1
ENST00000373560.7
ENST00000373568.7
ENST00000373573.9
ENST00000647654.1
ENST00000647859.1
ENST00000415409.6
ENST00000648298.1
ENST00000649752.1
ENST00000373571.6
ENST00000647980.1
ENST00000650126.1
ENST00000373554.6
ENST00000648870.1
ENST00000373556.8
ENST00000647886.1
ENST00000648452.1
ENST00000647594.1
ENST00000373583.6
ENST00000648922.1
histone deacetylase 8
novel protein
chr14_+_24232921 0.84 ENST00000557854.5
ENST00000399440.7
ENST00000559104.5
ENST00000456667.7
guanosine monophosphate reductase 2
chr16_-_75433391 0.84 ENST00000566254.1
ENST00000283882.4
craniofacial development protein 1
chr16_+_4624811 0.84 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
mahogunin ring finger 1
chr8_-_98117110 0.84 ENST00000520507.5
reactive intermediate imine deaminase A homolog
chr14_+_23555983 0.84 ENST00000404535.3
thiamine triphosphatase
chr14_-_67674583 0.84 ENST00000554659.6
vesicle transport through interaction with t-SNAREs 1B
chr3_-_100993409 0.83 ENST00000471714.6
ABI family member 3 binding protein
chr19_+_44259903 0.83 ENST00000588489.5
ENST00000391958.6
zinc finger protein 233
chr19_+_56404314 0.83 ENST00000333201.13
ENST00000391778.3
zinc finger protein 583
chr6_-_43014254 0.83 ENST00000642748.1
male-enhanced antigen 1
chr15_-_78077657 0.83 ENST00000300584.8
ENST00000409931.7
TBC1 domain family member 2B
chrX_-_49073989 0.83 ENST00000376386.3
ENST00000553851.3
PRA1 domain family member 2
chr15_+_75023576 0.82 ENST00000564923.5
ENST00000569562.5
ENST00000342932.8
ENST00000568649.5
phosphopantothenoylcysteine decarboxylase
chr5_-_82278341 0.82 ENST00000510210.5
ENST00000512493.5
ENST00000296674.13
ENST00000507980.1
ENST00000511844.1
ENST00000651545.1
ribosomal protein S23
chr11_+_114439424 0.81 ENST00000544196.5
ENST00000265881.10
ENST00000539754.5
ENST00000539275.5
RNA exonuclease 2
chr1_+_149899618 0.81 ENST00000369150.1
bolA family member 1
chr19_+_44165067 0.81 ENST00000590578.5
ENST00000589160.5
ENST00000586286.5
ENST00000337433.10
ENST00000585560.5
ENST00000586914.5
ENST00000588883.5
ENST00000413984.6
ENST00000588742.5
ENST00000300823.10
ENST00000585678.5
ENST00000586203.5
ENST00000590467.5
ENST00000588795.5
ENST00000588127.5
zinc finger protein 226
chr12_+_120534697 0.81 ENST00000675818.1
ENST00000413266.6
novel protein
ring finger protein 10
chr2_+_202912214 0.80 ENST00000402905.7
ENST00000320443.12
ENST00000414490.5
ENST00000431787.5
ENST00000444724.5
ENST00000414857.5
ENST00000438828.4
ENST00000430899.5
ENST00000445120.5
ENST00000441569.5
ENST00000432024.5
ENST00000443740.5
ENST00000414439.5
ENST00000428585.5
ENST00000447539.5
ENST00000434998.5
calcium responsive transcription factor
chr13_-_32538683 0.80 ENST00000674456.1
ENST00000504114.5
NEDD4 binding protein 2 like 2
chr7_+_140696665 0.80 ENST00000476279.5
ENST00000461457.1
ENST00000465506.5
NADH:ubiquinone oxidoreductase subunit B2
chr20_+_47501875 0.80 ENST00000371998.8
ENST00000372004.7
nuclear receptor coactivator 3
chr1_+_156767526 0.80 ENST00000271526.9
proline rich mitotic checkpoint control factor
chr14_+_24232892 0.79 ENST00000420554.6
guanosine monophosphate reductase 2
chr19_-_35745391 0.79 ENST00000378975.8
ENST00000587886.2
ENST00000412391.6
ENST00000292879.9
U2 small nuclear RNA auxiliary factor 1 like 4
chr7_+_100119607 0.79 ENST00000262932.5
canopy FGF signaling regulator 4
chr3_-_49429304 0.79 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
novel protein
nicolin 1
chr13_-_30306997 0.78 ENST00000380617.7
ENST00000441394.1
katanin catalytic subunit A1 like 1
chr19_+_44094380 0.78 ENST00000336976.10
zinc finger protein 224
chr15_+_64094060 0.78 ENST00000560829.5
sorting nexin 1
chr11_+_76445001 0.78 ENST00000533988.5
ENST00000524490.5
ENST00000334736.7
ENST00000533972.5
EMSY transcriptional repressor, BRCA2 interacting
chr14_+_77320996 0.77 ENST00000361389.8
ENST00000554279.5
ENST00000557639.5
ENST00000349555.7
ENST00000216465.10
ENST00000556627.5
ENST00000557053.5
glutathione S-transferase zeta 1
chr19_+_36850358 0.77 ENST00000589046.1
zinc finger protein 345
chr5_-_173616588 0.77 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
biorientation of chromosomes in cell division 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
1.1 3.3 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.9 2.6 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.5 1.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.5 1.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.5 4.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.5 4.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.4 1.9 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.4 1.8 GO:0019075 virus maturation(GO:0019075)
0.3 1.7 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 1.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.3 1.6 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.3 1.0 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.3 0.9 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.3 5.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.3 1.8 GO:0035624 receptor transactivation(GO:0035624)
0.3 1.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.3 5.3 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.3 1.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.3 1.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 1.4 GO:0051697 protein delipidation(GO:0051697)
0.2 0.7 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.2 0.7 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.7 GO:0036292 DNA rewinding(GO:0036292)
0.2 0.6 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 0.6 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.2 1.2 GO:0006574 valine catabolic process(GO:0006574)
0.2 2.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 2.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.2 0.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 1.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 1.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 2.4 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 3.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 1.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 1.1 GO:0044211 CTP salvage(GO:0044211)
0.1 9.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 1.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 1.3 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 2.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 1.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.5 GO:0006172 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.4 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 1.0 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0015847 putrescine transport(GO:0015847)
0.1 1.8 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 1.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.3 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.3 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.3 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 2.9 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 1.5 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.8 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 2.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1 0.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 2.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 3.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 3.0 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 0.5 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 6.4 GO:0048678 response to axon injury(GO:0048678)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.6 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.6 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0060661 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.5 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 4.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.5 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.2 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 1.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.9 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.7 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.8 GO:1901661 quinone metabolic process(GO:1901661)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 5.8 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.0 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 3.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 5.3 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.5 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.5 GO:0035878 nail development(GO:0035878)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.9 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 1.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0045008 depyrimidination(GO:0045008)
0.0 0.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.9 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 1.6 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 2.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.8 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.2 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 1.3 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.4 GO:0098792 xenophagy(GO:0098792)
0.0 0.1 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.0 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.2 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.8 GO:0044458 motile cilium assembly(GO:0044458)
0.0 2.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 1.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0032401 establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.0 0.4 GO:1903671 negative regulation of sprouting angiogenesis(GO:1903671)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 1.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.4 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 3.3 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 1.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 5.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.5 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.6 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.8 4.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 2.9 GO:1902560 GMP reductase complex(GO:1902560)
0.6 1.7 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.5 4.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.5 1.4 GO:1902636 kinociliary basal body(GO:1902636)
0.3 2.6 GO:0072687 meiotic spindle(GO:0072687)
0.2 1.2 GO:0035339 SPOTS complex(GO:0035339)
0.2 0.6 GO:0097224 sperm connecting piece(GO:0097224)
0.2 1.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 1.2 GO:0031417 NatC complex(GO:0031417)
0.2 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.2 0.7 GO:0035517 PR-DUB complex(GO:0035517)
0.2 3.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 0.5 GO:0008623 CHRAC(GO:0008623)
0.2 0.3 GO:0055087 Ski complex(GO:0055087)
0.2 7.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 1.1 GO:0002177 manchette(GO:0002177)
0.2 1.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.2 GO:0071986 Ragulator complex(GO:0071986)
0.1 2.0 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 2.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.0 GO:0030897 HOPS complex(GO:0030897)
0.1 1.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 0.5 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 1.8 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0089701 U2AF(GO:0089701)
0.1 1.7 GO:0071203 WASH complex(GO:0071203)
0.1 8.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.3 GO:0000124 SAGA complex(GO:0000124)
0.1 2.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.3 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 2.3 GO:0036020 endolysosome membrane(GO:0036020)
0.1 1.1 GO:0051286 cell tip(GO:0051286)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.8 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 2.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 5.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.1 GO:0034464 BBSome(GO:0034464)
0.1 1.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 1.2 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.1 0.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 4.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.1 GO:0070469 respiratory chain(GO:0070469)
0.1 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 0.4 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.4 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 2.2 GO:0016592 mediator complex(GO:0016592)
0.0 1.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 2.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0044447 axoneme part(GO:0044447)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.9 2.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.8 4.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.7 2.0 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.6 1.7 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.6 5.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.6 2.9 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.4 2.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 1.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.4 1.4 GO:0002046 opsin binding(GO:0002046)
0.3 1.6 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3 1.0 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.3 2.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 1.7 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 1.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 3.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.8 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 0.6 GO:0035514 DNA demethylase activity(GO:0035514)
0.2 1.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.9 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 0.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.2 5.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.8 GO:1990460 leptin receptor binding(GO:1990460)
0.2 3.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 0.5 GO:0047025 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 9.9 GO:0070888 E-box binding(GO:0070888)
0.1 3.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.0 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.5 GO:0032089 NACHT domain binding(GO:0032089)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.9 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 2.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 3.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.6 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 1.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.3 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.1 GO:0030911 TPR domain binding(GO:0030911)
0.1 1.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.7 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.3 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 1.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 1.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 4.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 1.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.7 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 1.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 4.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 6.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 2.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 6.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 2.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 30.8 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 21.6 GO:0003677 DNA binding(GO:0003677)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.1 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.8 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.2 PID MYC PATHWAY C-MYC pathway
0.1 3.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 3.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 3.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 1.3 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 4.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 7.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 42.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 8.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 2.4 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 1.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 3.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.3 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases