Project

avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation
Downloads

Results for SOX1

Z-value: 0.33

Motif logo

logo of

Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
SOX1
ENSG00000182968.5 SRY-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX1hg38_v1_chr13_+_112067143_112067160-0.226.0e-01Click!

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_130421086 0.57 ENST00000545622.5
TMEM200A
transmembrane protein 200A
chr3_-_190122317 0.56 ENST00000427335.6
P3H2
prolyl 3-hydroxylase 2
chr16_+_11965193 0.39 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr3_+_136957948 0.34 ENST00000329582.9
IL20RB
interleukin 20 receptor subunit beta
chr1_+_152985231 0.28 ENST00000368762.1
SPRR1A
small proline rich protein 1A
chr1_-_12616762 0.27 ENST00000464917.5
DHRS3
dehydrogenase/reductase 3
chr2_+_101998955 0.26 ENST00000393414.6
IL1R2
interleukin 1 receptor type 2
chr8_-_109680812 0.24 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
SYBU
syntabulin
chr1_+_70411241 0.20 ENST00000370938.8
ENST00000346806.2
CTH
cystathionine gamma-lyase
chr8_-_109608055 0.19 ENST00000529690.5
SYBU
syntabulin
chr13_+_108596152 0.19 ENST00000356711.7
ENST00000251041.10
MYO16
myosin XVI
chr17_-_41489907 0.18 ENST00000328119.11
KRT36
keratin 36
chr13_+_32316063 0.18 ENST00000680887.1
BRCA2
BRCA2 DNA repair associated
chr20_-_14337602 0.18 ENST00000378053.3
ENST00000341420.5
FLRT3
fibronectin leucine rich transmembrane protein 3
chrX_+_106168297 0.16 ENST00000337685.6
ENST00000357175.6
PWWP3B
PWWP domain containing 3B
chr11_-_133845495 0.13 ENST00000299140.8
ENST00000532889.1
SPATA19
spermatogenesis associated 19
chr1_+_32209074 0.12 ENST00000409358.2
DCDC2B
doublecortin domain containing 2B
chr9_-_101487120 0.12 ENST00000374848.8
PGAP4
post-GPI attachment to proteins GalNAc transferase 4
chr4_-_73620629 0.12 ENST00000342081.7
RASSF6
Ras association domain family member 6
chr8_+_144078590 0.12 ENST00000525936.1
EXOSC4
exosome component 4
chr5_-_16916400 0.12 ENST00000513882.5
MYO10
myosin X
chr17_-_31297231 0.11 ENST00000247271.5
OMG
oligodendrocyte myelin glycoprotein
chr8_+_144078661 0.11 ENST00000316052.6
EXOSC4
exosome component 4
chr9_-_2844058 0.11 ENST00000397885.3
PUM3
pumilio RNA binding family member 3
chr12_-_120325936 0.11 ENST00000549767.1
PLA2G1B
phospholipase A2 group IB
chrX_-_32412220 0.11 ENST00000619831.5
DMD
dystrophin
chr3_-_33645433 0.11 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2
chr1_-_200410001 0.10 ENST00000367353.2
ZNF281
zinc finger protein 281
chr4_+_69995958 0.10 ENST00000381060.2
ENST00000246895.9
STATH
statherin
chr11_-_57410113 0.09 ENST00000529411.1
ENSG00000254979.5
novel protein
chrX_+_129906146 0.09 ENST00000394422.8
UTP14A
UTP14A small subunit processome component
chr6_+_26183750 0.08 ENST00000614097.3
H2BC6
H2B clustered histone 6
chr17_-_69150062 0.08 ENST00000522787.5
ENST00000521538.5
ABCA10
ATP binding cassette subfamily A member 10
chr6_-_70957029 0.08 ENST00000230053.11
B3GAT2
beta-1,3-glucuronyltransferase 2
chr3_-_58214671 0.08 ENST00000460422.1
ENST00000483681.5
DNASE1L3
deoxyribonuclease 1 like 3
chr2_-_162318129 0.08 ENST00000679938.1
IFIH1
interferon induced with helicase C domain 1
chrX_+_129906118 0.07 ENST00000425117.6
UTP14A
UTP14A small subunit processome component
chr1_-_200409976 0.07 ENST00000367352.3
ZNF281
zinc finger protein 281
chr11_+_6863057 0.07 ENST00000641461.1
OR10A2
olfactory receptor family 10 subfamily A member 2
chr3_+_158644510 0.07 ENST00000486715.6
ENST00000478576.5
ENST00000264263.9
ENST00000464732.1
GFM1
G elongation factor mitochondrial 1
chr4_-_74794514 0.07 ENST00000395743.8
BTC
betacellulin
chr11_+_4704782 0.07 ENST00000380390.6
MMP26
matrix metallopeptidase 26
chr1_-_200410052 0.07 ENST00000294740.3
ZNF281
zinc finger protein 281
chr12_-_9999176 0.07 ENST00000298527.10
ENST00000348658.4
CLEC1B
C-type lectin domain family 1 member B
chr2_-_208190001 0.06 ENST00000451346.5
ENST00000341287.9
C2orf80
chromosome 2 open reading frame 80
chr1_-_169485931 0.06 ENST00000367804.4
ENST00000646596.1
ENST00000236137.10
SLC19A2
solute carrier family 19 member 2
chr19_+_17719471 0.06 ENST00000600186.5
ENST00000597735.5
ENST00000324096.9
MAP1S
microtubule associated protein 1S
chr11_-_47378494 0.06 ENST00000533030.1
SPI1
Spi-1 proto-oncogene
chr6_+_123804141 0.06 ENST00000368416.5
NKAIN2
sodium/potassium transporting ATPase interacting 2
chr9_-_127847117 0.06 ENST00000480266.5
ENG
endoglin
chr11_-_47378391 0.06 ENST00000227163.8
SPI1
Spi-1 proto-oncogene
chr1_+_174799895 0.06 ENST00000489615.5
RABGAP1L
RAB GTPase activating protein 1 like
chrX_-_72877864 0.06 ENST00000596389.5
DMRTC1
DMRT like family C1
chr1_-_183653307 0.06 ENST00000308641.6
APOBEC4
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr20_+_33217325 0.05 ENST00000375452.3
ENST00000375454.8
BPIFA3
BPI fold containing family A member 3
chr10_-_43397220 0.05 ENST00000477108.5
ENST00000544000.5
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_-_43172504 0.05 ENST00000431635.6
EBNA1BP2
EBNA1 binding protein 2
chr1_-_19251509 0.05 ENST00000375199.7
ENST00000375208.7
ENST00000477853.6
EMC1
ER membrane protein complex subunit 1
chr17_+_36064265 0.04 ENST00000616054.2
CCL18
C-C motif chemokine ligand 18
chr19_+_35351552 0.04 ENST00000246553.3
FFAR1
free fatty acid receptor 1
chr11_+_103109398 0.04 ENST00000648198.1
ENST00000375735.7
ENST00000650373.2
DYNC2H1
dynein cytoplasmic 2 heavy chain 1
chr2_-_162318475 0.04 ENST00000648433.1
IFIH1
interferon induced with helicase C domain 1
chr13_-_60163764 0.04 ENST00000377908.6
ENST00000400319.5
ENST00000400320.5
ENST00000267215.8
DIAPH3
diaphanous related formin 3
chr10_+_76318330 0.04 ENST00000496424.2
LRMDA
leucine rich melanocyte differentiation associated
chr1_-_52033772 0.04 ENST00000371614.2
KTI12
KTI12 chromatin associated homolog
chr19_+_49085433 0.04 ENST00000221448.9
ENST00000598441.6
SNRNP70
small nuclear ribonucleoprotein U1 subunit 70
chr11_-_113706330 0.04 ENST00000540540.5
ENST00000538955.5
ENST00000545579.6
TMPRSS5
transmembrane serine protease 5
chr15_+_40382715 0.04 ENST00000416151.6
ENST00000249776.12
KNSTRN
kinetochore localized astrin (SPAG5) binding protein
chr22_-_30266839 0.03 ENST00000403463.1
ENST00000215781.3
OSM
oncostatin M
chr4_-_170003738 0.03 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chr2_+_170178136 0.03 ENST00000409044.7
ENST00000408978.9
MYO3B
myosin IIIB
chr3_+_178558700 0.03 ENST00000432997.5
ENST00000455865.5
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr15_-_45114149 0.03 ENST00000603300.1
ENST00000389039.11
DUOX2
dual oxidase 2
chr10_-_72217126 0.03 ENST00000317126.8
ASCC1
activating signal cointegrator 1 complex subunit 1
chr15_+_59611776 0.03 ENST00000396065.3
ENST00000560585.5
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr6_+_63635792 0.03 ENST00000262043.8
ENST00000506783.5
ENST00000481385.6
ENST00000515594.5
ENST00000494284.6
PHF3
PHD finger protein 3
chr7_-_105389365 0.03 ENST00000482897.5
SRPK2
SRSF protein kinase 2
chr7_-_26200734 0.03 ENST00000354667.8
ENST00000618183.5
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr17_-_17281232 0.03 ENST00000417352.5
ENST00000268717.10
COPS3
COP9 signalosome subunit 3
chr8_-_85378105 0.02 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
CA1
carbonic anhydrase 1
chr7_-_93219564 0.02 ENST00000341723.8
HEPACAM2
HEPACAM family member 2
chr7_-_93219545 0.02 ENST00000440868.5
HEPACAM2
HEPACAM family member 2
chr3_+_128051610 0.02 ENST00000464451.5
SEC61A1
SEC61 translocon subunit alpha 1
chrX_+_49171889 0.02 ENST00000376327.6
PLP2
proteolipid protein 2
chr11_-_113706292 0.02 ENST00000544634.5
ENST00000539732.5
ENST00000538770.1
ENST00000536856.5
ENST00000299882.11
ENST00000544476.1
TMPRSS5
transmembrane serine protease 5
chr15_-_73753308 0.02 ENST00000569673.3
INSYN1
inhibitory synaptic factor 1
chr19_-_10380454 0.02 ENST00000530829.1
ENST00000529370.5
TYK2
tyrosine kinase 2
chr7_-_86965872 0.02 ENST00000398276.6
ENST00000416314.5
ENST00000425689.1
ELAPOR2
endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr1_+_240091866 0.02 ENST00000319653.14
FMN2
formin 2
chr1_+_84479239 0.02 ENST00000370656.5
ENST00000370654.6
RPF1
ribosome production factor 1 homolog
chr10_-_72216267 0.02 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
ASCC1
activating signal cointegrator 1 complex subunit 1
chr18_+_24139053 0.02 ENST00000463087.5
ENST00000585037.5
ENST00000399496.8
ENST00000486759.6
ENST00000577705.1
ENST00000415309.6
ENST00000621648.4
ENST00000581397.5
CABYR
calcium binding tyrosine phosphorylation regulated
chr9_-_111328520 0.02 ENST00000374428.1
OR2K2
olfactory receptor family 2 subfamily K member 2
chr17_-_4641670 0.02 ENST00000293761.8
ALOX15
arachidonate 15-lipoxygenase
chr1_-_86383078 0.02 ENST00000460698.6
ODF2L
outer dense fiber of sperm tails 2 like
chr2_-_162318613 0.02 ENST00000649979.2
ENST00000421365.2
IFIH1
interferon induced with helicase C domain 1
chr18_-_54224578 0.02 ENST00000583046.1
ENST00000398398.6
ENST00000256429.8
MBD2
methyl-CpG binding domain protein 2
chr3_+_11011640 0.02 ENST00000643396.1
SLC6A1
solute carrier family 6 member 1
chr19_+_51761167 0.02 ENST00000340023.7
ENST00000599326.1
ENST00000598953.1
FPR2
formyl peptide receptor 2
chr17_+_77185210 0.02 ENST00000431431.6
SEC14L1
SEC14 like lipid binding 1
chr17_-_40665121 0.01 ENST00000394052.5
KRT222
keratin 222
chr11_-_26572130 0.01 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chrX_-_56995508 0.01 ENST00000374919.6
ENST00000639007.1
ENST00000639583.1
ENST00000638289.1
ENST00000639525.1
ENST00000638386.1
SPIN3
spindlin family member 3
chr11_+_125626229 0.01 ENST00000532449.6
ENST00000534070.5
CHEK1
checkpoint kinase 1
chr1_+_65147514 0.01 ENST00000545314.5
AK4
adenylate kinase 4
chrX_-_56995426 0.01 ENST00000640768.1
ENST00000638619.1
SPIN3
spindlin family member 3
chr1_+_203795614 0.01 ENST00000367210.3
ENST00000432282.5
ENST00000453771.5
ENST00000367214.5
ENST00000639812.1
ENST00000367212.7
ENST00000332127.8
ENST00000550078.2
ZC3H11A
ZBED6
zinc finger CCCH-type containing 11A
zinc finger BED-type containing 6
chr12_-_109996291 0.01 ENST00000320063.10
ENST00000457474.6
ENST00000547815.5
ENST00000361006.9
ENST00000355312.8
ENST00000354574.8
ENST00000553118.5
GIT2
GIT ArfGAP 2
chr4_+_155758990 0.00 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
chr12_+_92702843 0.00 ENST00000397833.3
PLEKHG7
pleckstrin homology and RhoGEF domain containing G7
chr14_-_60165363 0.00 ENST00000557185.6
DHRS7
dehydrogenase/reductase 7
chr19_+_54874218 0.00 ENST00000355524.8
ENST00000391726.7
FCAR
Fc fragment of IgA receptor
chrX_+_11111291 0.00 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
HCCS
holocytochrome c synthase

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease