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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SOX7

Z-value: 0.37

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
SOX7
ENSG00000171056.8 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PINX1hg38_v1_chr8_-_10839818_108398550.811.6e-02Click!
SOX7hg38_v1_chr8_-_10730498_107305250.801.8e-02Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_68447453 0.25 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr19_-_38426195 0.20 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RASGRP4
RAS guanyl releasing protein 4
chr1_-_206003442 0.20 ENST00000623893.1
RAB7B
RAB7B, member RAS oncogene family
chr19_-_38426162 0.17 ENST00000587738.2
ENST00000586305.5
RASGRP4
RAS guanyl releasing protein 4
chr1_-_206003385 0.13 ENST00000617070.5
RAB7B
RAB7B, member RAS oncogene family
chr10_+_24449426 0.13 ENST00000307544.10
KIAA1217
KIAA1217
chr6_+_116399395 0.12 ENST00000644499.1
ENSG00000285446.1
novel protein
chr8_-_86069662 0.11 ENST00000276616.3
PSKH2
protein serine kinase H2
chr1_+_86993009 0.11 ENST00000370548.3
ENSG00000267561.2
novel protein
chr12_-_10998304 0.11 ENST00000538986.2
TAS2R20
taste 2 receptor member 20
chr6_+_143843316 0.10 ENST00000367576.6
LTV1
LTV1 ribosome biogenesis factor
chr6_-_85594063 0.10 ENST00000684150.1
SNX14
sorting nexin 14
chr5_+_162067858 0.10 ENST00000361925.9
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_-_85594101 0.10 ENST00000682171.1
ENST00000505648.5
SNX14
sorting nexin 14
chr5_+_162067764 0.08 ENST00000639213.2
ENST00000414552.6
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr4_+_74308463 0.08 ENST00000413830.6
EPGN
epithelial mitogen
chr12_-_39340963 0.08 ENST00000552961.5
KIF21A
kinesin family member 21A
chr1_-_26067622 0.08 ENST00000374272.4
TRIM63
tripartite motif containing 63
chr4_+_76074701 0.07 ENST00000355810.9
ENST00000349321.7
ART3
ADP-ribosyltransferase 3 (inactive)
chr12_+_63779894 0.07 ENST00000261234.11
RXYLT1
ribitol xylosyltransferase 1
chr5_+_162067500 0.07 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr10_+_4963406 0.06 ENST00000380872.9
ENST00000442997.5
AKR1C1
aldo-keto reductase family 1 member C1
chr11_+_35186820 0.06 ENST00000531110.6
ENST00000525685.6
CD44
CD44 molecule (Indian blood group)
chrX_+_131083706 0.06 ENST00000370921.1
ARHGAP36
Rho GTPase activating protein 36
chr5_+_162067458 0.05 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_+_42563981 0.05 ENST00000372899.6
ENST00000372901.2
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_+_100133135 0.05 ENST00000370143.5
ENST00000370141.7
TRMT13
tRNA methyltransferase 13 homolog
chr10_-_12042771 0.05 ENST00000357604.10
UPF2
UPF2 regulator of nonsense mediated mRNA decay
chr1_+_207325629 0.05 ENST00000618707.2
CD55
CD55 molecule (Cromer blood group)
chr13_+_94601830 0.04 ENST00000376958.5
GPR180
G protein-coupled receptor 180
chrX_-_135781729 0.04 ENST00000617203.1
CT45A5
cancer/testis antigen family 45 member A5
chrX_+_51710512 0.03 ENST00000602548.2
CENPVL1
centromere protein V like 1
chr15_+_75347030 0.03 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
NEIL1
nei like DNA glycosylase 1
chr1_+_158931539 0.03 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
PYHIN1
pyrin and HIN domain family member 1
chr7_-_138755892 0.03 ENST00000644341.1
ENST00000478480.2
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr4_-_122456725 0.03 ENST00000226730.5
IL2
interleukin 2
chr21_-_14546297 0.03 ENST00000400566.6
ENST00000400564.5
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_200027605 0.02 ENST00000236914.7
NR5A2
nuclear receptor subfamily 5 group A member 2
chr2_+_86907953 0.02 ENST00000409776.6
RGPD1
RANBP2 like and GRIP domain containing 1
chr2_-_89100352 0.02 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr19_-_5784599 0.02 ENST00000390672.2
ENST00000419421.3
PRR22
proline rich 22
chr17_-_35880350 0.02 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
CCL5
C-C motif chemokine ligand 5
chr19_-_2783241 0.02 ENST00000676943.1
ENST00000589251.5
ENST00000221566.7
ENST00000676984.1
SGTA
small glutamine rich tetratricopeptide repeat containing alpha
chr6_+_150368997 0.02 ENST00000392255.7
ENST00000500320.7
ENST00000344419.8
IYD
iodotyrosine deiodinase
chr1_+_200027702 0.02 ENST00000367362.8
NR5A2
nuclear receptor subfamily 5 group A member 2
chr19_-_2783308 0.01 ENST00000677562.1
ENST00000677754.1
SGTA
small glutamine rich tetratricopeptide repeat containing alpha
chr6_+_150368892 0.01 ENST00000229447.9
ENST00000392256.6
IYD
iodotyrosine deiodinase
chr8_+_127409026 0.01 ENST00000465342.4
POU5F1B
POU class 5 homeobox 1B
chr1_-_158426237 0.01 ENST00000641042.1
OR10K2
olfactory receptor family 10 subfamily K member 2
chr3_-_36993103 0.01 ENST00000322716.8
EPM2AIP1
EPM2A interacting protein 1
chr8_+_12945667 0.00 ENST00000524591.7
TRMT9B
tRNA methyltransferase 9B (putative)
chr19_+_34926892 0.00 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
ZNF30
zinc finger protein 30
chr4_-_176269213 0.00 ENST00000296525.7
ASB5
ankyrin repeat and SOCS box containing 5
chr9_+_102995308 0.00 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
CYLC2
cylicin 2
chr3_+_107599309 0.00 ENST00000406780.5
BBX
BBX high mobility group box domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034448 EGO complex(GO:0034448)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)