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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SPIB

Z-value: 1.98

Motif logo

Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
ENSG00000269404.7 Spi-B transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIBhg38_v1_chr19_+_50418930_50418958-0.098.3e-01Click!

Activity profile of SPIB motif

Sorted Z-values of SPIB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_43593054 1.57 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr15_+_43692886 1.55 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr2_-_70553638 1.33 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr9_+_90801909 1.23 ENST00000375747.5
spleen associated tyrosine kinase
chr9_+_90801757 1.19 ENST00000375751.8
ENST00000375754.9
spleen associated tyrosine kinase
chr20_-_47786553 1.13 ENST00000467815.5
ENST00000359930.8
ENST00000484875.5
sulfatase 2
chr13_+_36431510 0.99 ENST00000630422.2
cyclin A1
chr16_+_30183595 0.93 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr12_-_51391398 0.93 ENST00000356317.8
ENST00000603188.5
ENST00000604847.5
ENST00000604506.5
polypeptide N-acetylgalactosaminyltransferase 6
chrX_+_106693838 0.92 ENST00000324342.7
ring finger protein 128
chr11_+_1840168 0.89 ENST00000381905.3
troponin I2, fast skeletal type
chr11_+_1839602 0.87 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr2_-_70553440 0.87 ENST00000450929.5
transforming growth factor alpha
chr2_+_113127588 0.86 ENST00000409930.4
interleukin 1 receptor antagonist
chr10_-_96271508 0.85 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr17_-_58415628 0.84 ENST00000583753.5
ring finger protein 43
chr1_+_205504644 0.81 ENST00000429964.7
ENST00000443813.6
cyclin dependent kinase 18
chr1_-_175192769 0.79 ENST00000423313.6
KIAA0040
chr13_+_36431898 0.73 ENST00000440264.5
cyclin A1
chr1_+_205504592 0.72 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chr10_-_96271553 0.71 ENST00000224337.10
B cell linker
chr6_-_47042306 0.67 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr5_+_35856883 0.67 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr2_+_113173950 0.64 ENST00000245796.11
ENST00000441564.7
pleckstrin and Sec7 domain containing 4
chr11_-_125592448 0.63 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr15_+_45129933 0.63 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr17_-_45410414 0.57 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr4_+_102501885 0.56 ENST00000505458.5
nuclear factor kappa B subunit 1
chr15_+_76995118 0.56 ENST00000558012.6
ENST00000379595.7
proline-serine-threonine phosphatase interacting protein 1
chr1_+_161706949 0.51 ENST00000350710.3
ENST00000367949.6
ENST00000367959.6
ENST00000540521.5
ENST00000546024.5
ENST00000674251.1
ENST00000674323.1
Fc receptor like A
chr22_+_36913620 0.51 ENST00000403662.8
ENST00000262825.9
colony stimulating factor 2 receptor subunit beta
chr6_+_116461364 0.50 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr19_+_53867874 0.49 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
myeloid associated differentiation marker
chr1_+_161707205 0.48 ENST00000367957.7
Fc receptor like A
chr19_-_50968125 0.48 ENST00000594641.1
kallikrein related peptidase 6
chr6_+_130018565 0.48 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr1_+_161707222 0.48 ENST00000236938.12
Fc receptor like A
chr8_+_22059169 0.47 ENST00000358242.5
dematin actin binding protein
chr2_+_233060295 0.46 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr4_+_102501298 0.46 ENST00000394820.8
ENST00000226574.9
ENST00000511926.5
ENST00000507079.5
nuclear factor kappa B subunit 1
chr1_+_161707244 0.45 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
Fc receptor like A
chr3_-_116444983 0.45 ENST00000333617.8
limbic system associated membrane protein
chr8_+_22059198 0.44 ENST00000523266.5
ENST00000519907.5
dematin actin binding protein
chr2_+_233059838 0.44 ENST00000359570.9
inositol polyphosphate-5-phosphatase D
chr3_+_98763331 0.44 ENST00000485391.5
ENST00000492254.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr1_+_89821921 0.42 ENST00000394593.7
leucine rich repeat containing 8 VRAC subunit D
chrX_-_40735476 0.42 ENST00000324817.6
mediator complex subunit 14
chr10_-_97401277 0.42 ENST00000315563.10
ENST00000370992.9
ENST00000414986.5
ribosomal RNA processing 12 homolog
chr3_+_122077850 0.42 ENST00000482356.5
ENST00000393627.6
CD86 molecule
chr8_-_103501890 0.41 ENST00000649416.1
novel protein
chr10_+_95755737 0.40 ENST00000543964.6
ectonucleoside triphosphate diphosphohydrolase 1
chr16_+_3046552 0.39 ENST00000336577.9
matrix metallopeptidase 25
chr21_-_32813679 0.39 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr19_-_51531790 0.38 ENST00000359982.8
ENST00000436458.5
ENST00000391797.3
ENST00000343300.8
sialic acid binding Ig like lectin 6
chr3_+_46242453 0.38 ENST00000452454.1
ENST00000395940.3
ENST00000457243.1
C-C motif chemokine receptor 3
chr11_-_123654939 0.38 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr1_+_43974902 0.37 ENST00000532642.5
ENST00000236067.8
ENST00000471859.6
ENST00000472174.7
ATPase H+ transporting V0 subunit b
chr8_-_94436926 0.37 ENST00000481490.3
fibrinogen silencer binding protein
chr12_+_8950036 0.37 ENST00000539240.5
killer cell lectin like receptor G1
chr2_+_102355881 0.35 ENST00000409599.5
interleukin 18 receptor 1
chr3_+_46242371 0.35 ENST00000545097.1
C-C motif chemokine receptor 3
chr21_-_44920918 0.35 ENST00000522688.5
integrin subunit beta 2
chr6_-_47042260 0.34 ENST00000371243.2
adhesion G protein-coupled receptor F1
chr3_+_122055355 0.34 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr12_+_6951345 0.34 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
protein tyrosine phosphatase non-receptor type 6
chr7_+_141776674 0.34 ENST00000247881.4
taste 2 receptor member 4
chr4_-_102345469 0.34 ENST00000356736.5
ENST00000682932.1
solute carrier family 39 member 8
chr12_+_6951271 0.34 ENST00000456013.5
protein tyrosine phosphatase non-receptor type 6
chr6_+_15246054 0.33 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr4_-_86360010 0.33 ENST00000641911.1
ENST00000641072.1
ENST00000359221.8
ENST00000640490.1
mitogen-activated protein kinase 10
chr3_-_143848442 0.33 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr1_-_156705575 0.32 ENST00000368222.8
cellular retinoic acid binding protein 2
chr7_+_139829153 0.32 ENST00000652056.1
thromboxane A synthase 1
chr3_-_116445458 0.31 ENST00000490035.7
limbic system associated membrane protein
chr7_+_139829242 0.31 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chr1_-_160711803 0.31 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48 molecule
chr18_+_58362467 0.31 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chrX_-_153724044 0.31 ENST00000423827.5
ENST00000458587.8
B cell receptor associated protein 31
chr6_+_150683593 0.30 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr2_+_147844601 0.30 ENST00000404590.1
activin A receptor type 2A
chr10_+_100987529 0.30 ENST00000370228.2
ENST00000311916.8
ENST00000473656.5
twinkle mtDNA helicase
chr22_-_37519528 0.29 ENST00000403299.5
caspase recruitment domain family member 10
chr17_-_40937445 0.29 ENST00000436344.7
ENST00000485751.1
keratin 23
chr3_-_20186127 0.28 ENST00000425061.5
ENST00000443724.5
ENST00000421451.5
ENST00000452020.5
ENST00000417364.1
ENST00000306698.6
ENST00000419233.6
ENST00000263753.8
ENST00000437051.5
ENST00000442720.5
ENST00000412997.6
shugoshin 1
chr17_+_7558774 0.28 ENST00000396545.4
TNF superfamily member 13
chr22_-_37519349 0.28 ENST00000251973.10
caspase recruitment domain family member 10
chr2_+_134254065 0.28 ENST00000281923.4
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr1_-_26354080 0.28 ENST00000308182.10
crystallin beta-gamma domain containing 2
chr1_-_161038907 0.28 ENST00000318289.14
ENST00000368023.7
ENST00000423014.3
ENST00000368024.5
thiosulfate sulfurtransferase like domain containing 1
chrX_-_153724343 0.27 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
B cell receptor associated protein 31
chr9_-_34397800 0.27 ENST00000297623.7
chromosome 9 open reading frame 24
chr10_-_60389833 0.27 ENST00000280772.7
ankyrin 3
chr20_+_59163810 0.26 ENST00000371030.4
zinc finger protein 831
chr3_+_122077776 0.26 ENST00000264468.9
CD86 molecule
chr17_-_40937641 0.26 ENST00000209718.8
keratin 23
chr7_+_151114597 0.26 ENST00000335367.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_153946652 0.26 ENST00000361217.9
DENN domain containing 4B
chr19_+_17747737 0.26 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCH and mu domain containing endocytic adaptor 1
chr19_-_38426195 0.25 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr19_-_3786408 0.25 ENST00000395040.6
megakaryocyte-associated tyrosine kinase
chrX_-_75156272 0.25 ENST00000620875.5
ENST00000669573.1
ENST00000339447.8
ENST00000645829.3
ENST00000529949.5
ENST00000373394.8
ENST00000253577.9
ENST00000644766.1
ENST00000534524.5
ATP binding cassette subfamily B member 7
chr5_-_140633690 0.25 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr2_+_64524299 0.24 ENST00000238855.11
ENST00000238856.8
aftiphilin
chr10_-_90857983 0.24 ENST00000336152.8
5-hydroxytryptamine receptor 7
chr5_+_10250216 0.24 ENST00000515390.5
chaperonin containing TCP1 subunit 5
chr3_+_32391871 0.24 ENST00000465248.1
CKLF like MARVEL transmembrane domain containing 7
chr17_-_31314040 0.24 ENST00000330927.5
ecotropic viral integration site 2B
chr19_-_3479088 0.24 ENST00000587847.1
small integral membrane protein 24
chr2_+_168456215 0.23 ENST00000392687.4
ENST00000305747.11
ceramide synthase 6
chr11_-_59212869 0.23 ENST00000361050.4
macrophage expressed 1
chr17_+_7558465 0.23 ENST00000349228.8
TNF superfamily member 13
chr6_+_124983356 0.22 ENST00000519799.5
ENST00000368414.6
ENST00000359704.2
ring finger protein 217
chr12_-_14961256 0.22 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr2_-_70835808 0.22 ENST00000410009.5
CD207 molecule
chr19_-_38426162 0.22 ENST00000587738.2
ENST00000586305.5
RAS guanyl releasing protein 4
chr2_-_207167220 0.22 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr17_+_7558712 0.22 ENST00000338784.9
ENST00000625791.2
TNF superfamily member 13
chr1_-_206202419 0.22 ENST00000607379.1
ENST00000341209.9
family with sequence similarity 72 member A
chr7_+_74773962 0.22 ENST00000289473.10
neutrophil cytosolic factor 1
chr3_-_9249623 0.22 ENST00000383836.8
SLIT-ROBO Rho GTPase activating protein 3
chr13_-_110561668 0.22 ENST00000267328.5
RAB20, member RAS oncogene family
chr19_-_3478478 0.22 ENST00000591708.1
small integral membrane protein 24
chr8_+_66430185 0.22 ENST00000523113.5
novel protein
chr2_+_147844488 0.22 ENST00000535787.5
activin A receptor type 2A
chr10_+_95756150 0.21 ENST00000371205.5
ectonucleoside triphosphate diphosphohydrolase 1
chr19_-_46787278 0.21 ENST00000412532.6
solute carrier family 1 member 5
chr2_-_113235443 0.21 ENST00000465084.1
paired box 8
chr15_-_33067884 0.21 ENST00000334528.13
formin 1
chr8_-_100722174 0.21 ENST00000677380.1
ENST00000677478.1
poly(A) binding protein cytoplasmic 1
chr1_-_121183911 0.21 ENST00000355228.8
family with sequence similarity 72 member B
chr20_+_64080129 0.21 ENST00000355631.8
opioid related nociceptin receptor 1
chr3_-_112975018 0.21 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr1_-_43172244 0.21 ENST00000236051.3
EBNA1 binding protein 2
chr10_+_104268852 0.21 ENST00000450629.6
glutathione S-transferase omega 2
chr7_+_23597373 0.21 ENST00000307471.8
ENST00000409765.5
coiled-coil domain containing 126
chr8_+_124973288 0.21 ENST00000319286.6
zinc finger protein 572
chr1_+_89821003 0.20 ENST00000525774.5
ENST00000337338.9
leucine rich repeat containing 8 VRAC subunit D
chr8_-_100722036 0.20 ENST00000518196.5
ENST00000519004.5
ENST00000519363.1
ENST00000318607.10
ENST00000520142.2
poly(A) binding protein cytoplasmic 1
chr19_-_3786363 0.20 ENST00000310132.11
megakaryocyte-associated tyrosine kinase
chr21_-_32813695 0.20 ENST00000479548.2
ENST00000490358.5
chromosome 21 open reading frame 62
chr16_-_70801131 0.20 ENST00000261776.10
VAC14 component of PIKFYVE complex
chr9_-_2844058 0.20 ENST00000397885.3
pumilio RNA binding family member 3
chr1_+_145095967 0.20 ENST00000400889.3
family with sequence similarity 72 member D
chr14_+_75069577 0.20 ENST00000238686.8
zinc finger C2HC-type containing 1C
chr8_+_124539097 0.20 ENST00000606244.2
ENST00000276689.8
ENST00000518008.5
ENST00000517367.1
NADH:ubiquinone oxidoreductase subunit B9
chr3_-_155745016 0.20 ENST00000460012.7
phospholipase C eta 1
chr20_+_64080074 0.20 ENST00000336866.7
opioid related nociceptin receptor 1
chr8_-_100721851 0.20 ENST00000522658.6
poly(A) binding protein cytoplasmic 1
chr1_-_46604214 0.19 ENST00000371946.9
ENST00000428112.7
ENST00000529170.6
ENST00000371945.10
MAPK interacting serine/threonine kinase 1
chr1_-_121184292 0.19 ENST00000452190.2
ENST00000619376.4
ENST00000369390.7
family with sequence similarity 72 member B
chr1_-_46604283 0.19 ENST00000341183.9
ENST00000649800.1
ENST00000650026.1
ENST00000650508.1
ENST00000496619.6
MAPK interacting serine/threonine kinase 1
chr1_-_143971965 0.19 ENST00000369175.4
ENST00000584486.6
family with sequence similarity 72 member C
chr21_-_44920855 0.19 ENST00000397854.7
integrin subunit beta 2
chr14_+_32076939 0.19 ENST00000556611.5
ENST00000539826.6
Rho GTPase activating protein 5
chr17_+_43483949 0.19 ENST00000540306.5
ENST00000262415.8
DEAH-box helicase 8
chr1_-_206202827 0.19 ENST00000431655.2
ENST00000367128.8
family with sequence similarity 72 member A
chr1_-_202958258 0.18 ENST00000367254.7
ENST00000426229.1
ENST00000340990.10
adiponectin receptor 1
chr9_+_124862098 0.18 ENST00000353214.6
actin related protein 2/3 complex subunit 5 like
chr1_+_111473792 0.18 ENST00000343534.9
chromosome 1 open reading frame 162
chr5_+_40909490 0.18 ENST00000313164.10
complement C7
chr12_+_123602085 0.18 ENST00000238146.9
ENST00000538744.5
DEAD-box helicase 55
chr11_+_63839173 0.18 ENST00000502399.7
ENST00000425897.3
ENST00000513765.7
ENST00000679216.1
microtubule affinity regulating kinase 2
chr1_-_23559490 0.17 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr12_-_8066331 0.17 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr8_-_100721583 0.17 ENST00000610907.2
ENST00000677140.1
ENST00000677787.1
ENST00000679197.1
ENST00000519100.6
poly(A) binding protein cytoplasmic 1
chr7_-_36724543 0.17 ENST00000612871.4
acyloxyacyl hydrolase
chr6_-_142946312 0.17 ENST00000367604.6
HIVEP zinc finger 2
chr11_-_60952067 0.17 ENST00000681275.1
solute carrier family 15 member 3
chr12_-_14961559 0.17 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr7_-_122304738 0.17 ENST00000442488.7
FEZ family zinc finger 1
chr22_-_37484505 0.17 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_100721942 0.17 ENST00000522387.5
poly(A) binding protein cytoplasmic 1
chr7_+_23597499 0.16 ENST00000448353.5
coiled-coil domain containing 126
chr2_-_180007254 0.16 ENST00000410053.8
CWC22 spliceosome associated protein homolog
chr12_+_25052512 0.16 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr1_-_110963936 0.16 ENST00000485275.2
ligand dependent nuclear receptor interacting factor 1
chr1_+_46247731 0.16 ENST00000371975.9
ENST00000469835.6
RAD54 like
chr5_-_159330481 0.16 ENST00000231228.3
interleukin 12B
chr1_+_46247684 0.16 ENST00000463715.5
ENST00000442598.5
ENST00000493985.5
ENST00000671528.1
RAD54 like
chr4_+_8199363 0.16 ENST00000382521.7
ENST00000457650.7
SH3 domain and tetratricopeptide repeats 1
chr11_-_64744993 0.16 ENST00000377485.5
RAS guanyl releasing protein 2
chr1_-_110963897 0.16 ENST00000369763.5
ligand dependent nuclear receptor interacting factor 1
chr19_+_18193192 0.16 ENST00000599612.3
MPV17 mitochondrial inner membrane protein like 2
chr7_-_36724380 0.16 ENST00000617267.4
acyloxyacyl hydrolase
chr12_+_80716906 0.16 ENST00000228644.4
myogenic factor 5
chr4_+_8199239 0.16 ENST00000245105.8
SH3 domain and tetratricopeptide repeats 1
chr14_+_75069632 0.16 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr13_-_35476682 0.15 ENST00000379919.6
mab-21 like 1
chr16_+_11965193 0.15 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr9_-_112333603 0.15 ENST00000450374.1
ENST00000374257.6
ENST00000374255.6
ENST00000334318.10
polypyrimidine tract binding protein 3
chr19_+_51225059 0.15 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr4_-_86360039 0.15 ENST00000515650.2
ENST00000641724.1
ENST00000641607.1
ENST00000641324.1
ENST00000641903.1
ENST00000395157.9
ENST00000641823.1
ENST00000641873.1
ENST00000641102.1
ENST00000641462.2
ENST00000641217.1
ENST00000642006.1
ENST00000641020.1
ENST00000641110.1
ENST00000639175.1
ENST00000641485.1
ENST00000641864.1
ENST00000641954.1
ENST00000641647.1
ENST00000641459.1
ENST00000641762.1
ENST00000641777.1
ENST00000641208.1
ENST00000642015.1
ENST00000641493.1
ENST00000642032.1
ENST00000641010.1
ENST00000641287.1
ENST00000641943.1
ENST00000642103.1
ENST00000641047.1
ENST00000641166.1
ENST00000641207.1
mitogen-activated protein kinase 10
chr7_-_36724457 0.15 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr15_-_33068143 0.15 ENST00000558197.1
formin 1
chr11_-_60952559 0.15 ENST00000538739.2
solute carrier family 15 member 3
chr12_+_54053815 0.15 ENST00000430889.3
homeobox C4
chr6_+_26251607 0.15 ENST00000619466.2
H2B clustered histone 9
chr3_-_195876635 0.15 ENST00000672669.1
ENST00000672886.1
ENST00000672098.1
ENST00000671767.1
ENST00000672548.1
tyrosine kinase non receptor 2
chr11_+_70398404 0.15 ENST00000346329.7
ENST00000301843.13
ENST00000376561.7
cortactin
chr8_-_124539037 0.15 ENST00000519232.5
ENST00000523888.5
ENST00000522810.5
ENST00000519548.5
ENST00000517678.5
ENST00000605953.5
ENST00000276692.11
ENST00000630259.1
TatD DNase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0071226 response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
0.4 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.0 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.2 0.9 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.6 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 0.6 GO:0042335 cuticle development(GO:0042335)
0.2 0.9 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.6 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 2.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 1.6 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.9 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.2 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.2 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.4 GO:1904058 positive regulation of gastric acid secretion(GO:0060454) positive regulation of sensory perception of pain(GO:1904058)
0.0 0.3 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.7 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.7 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.6 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0051232 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.1 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.5 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.3 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:1904045 cellular response to aldosterone(GO:1904045)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) positive regulation of protein lipidation(GO:1903061)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 1.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.2 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.4 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0019815 B cell receptor complex(GO:0019815)
0.4 1.7 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 0.6 GO:0032449 CBM complex(GO:0032449)
0.1 0.7 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.8 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 2.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.6 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.6 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.6 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.9 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.4 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 2.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.8 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.4 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 0.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 1.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.7 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.2 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.3 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 2.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.9 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0061599 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives