ISMARA results: SREBF2

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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SREBF2

Z-value: 0.10

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Transcription factors associated with SREBF2

Gene Symbol	Gene ID	Gene Info
SREBF2 Ensembl NCBI GeneCards UniProt	ENSG00000198911.12	sterol regulatory element binding transcription factor 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SREBF2	hg38_v1_chr22_+_41833079_41833142	0.35	4.0e-01	Click!

Activity profile of SREBF2 motif

Sorted Z-values of SREBF2 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_103500696 Show fit	0.22	ENST00000666250.1 ENST00000668113.1 ENST00000504942.6 ENST00000632716.1	RIMS2 Ensembl NCBI GeneCards UniProt Show fit	regulating synaptic membrane exocytosis 2
chr1_+_55039511 Show fit	0.17	ENST00000302118.5	PCSK9 Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 9
chr10_-_114684612 Show fit	0.08	ENST00000533213.6 ENST00000369252.8	ABLIM1 Ensembl NCBI GeneCards UniProt Show fit	actin binding LIM protein 1
chr10_-_114684457 Show fit	0.08	ENST00000392955.7	ABLIM1 Ensembl NCBI GeneCards UniProt Show fit	actin binding LIM protein 1
chr3_+_50269140 Show fit	0.07	ENST00000616701.5 ENST00000433753.4 ENST00000611067.4	SEMA3B Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3B
chr8_-_123416327 Show fit	0.06	ENST00000521903.5	ATAD2 Ensembl NCBI GeneCards UniProt Show fit	ATPase family AAA domain containing 2
chr17_-_41118369 Show fit	0.06	ENST00000391413.4	KRTAP4-11 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 4-11
chrX_-_153971169 Show fit	0.06	ENST00000369984.4	HCFC1 Ensembl NCBI GeneCards UniProt Show fit	host cell factor C1
chrX_-_153971810 Show fit	0.06	ENST00000310441.12	HCFC1 Ensembl NCBI GeneCards UniProt Show fit	host cell factor C1
chr8_-_17722217 Show fit	0.05	ENST00000381861.7	MTUS1 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated scaffold protein 1

Showing 1 to 10 of 81 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
0.0	0.2	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0019046	release from viral latency(GO:0019046)
0.0	0.1	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.0	0.0	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)

Showing 1 to 5 of 5 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:1990666	PCSK9-LDLR complex(GO:1990666)

Showing 1 to 1 of 1 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.2	GO:0034189	very-low-density lipoprotein particle binding(GO:0034189)
0.0	GO:0047256	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0	GO:0016419	[acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)

Showing 1 to 3 of 3 entries

Results for SREBF2

Z-value: 0.10

Motif logo

Transcription factors associated with SREBF2

Activity-expression correlation:

Activity profile of SREBF2 motif

Sorted Z-values of SREBF2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: