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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TBP

Z-value: 2.92

Motif logo

Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
ENSG00000112592.14 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg38_v1_chr6_+_170554333_1705543960.324.4e-01Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52452139 3.93 ENST00000252252.4
keratin 6B
chr12_-_52473798 3.13 ENST00000252250.7
keratin 6C
chr1_+_153031195 2.83 ENST00000307098.5
small proline rich protein 1B
chr11_+_18266254 2.39 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr17_-_41518878 2.24 ENST00000254043.8
keratin 15
chr11_-_18248662 2.18 ENST00000256733.9
serum amyloid A2
chr19_-_6720641 2.17 ENST00000245907.11
complement C3
chr12_-_52493250 2.04 ENST00000330722.7
keratin 6A
chr1_-_153390976 2.00 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr20_-_45254556 1.88 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr1_+_153357846 1.80 ENST00000368738.4
S100 calcium binding protein A9
chr11_-_18248632 1.71 ENST00000524555.3
ENST00000528349.5
ENST00000526900.1
ENST00000529528.5
ENST00000414546.6
SAA2-SAA4 readthrough
serum amyloid A2
chr11_-_102780620 1.67 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr6_-_136526472 1.53 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr19_-_50984028 1.47 ENST00000597707.5
kallikrein related peptidase 7
chr9_-_33447553 1.46 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr6_-_136526654 1.40 ENST00000611373.1
microtubule associated protein 7
chr1_-_58577244 1.36 ENST00000371225.4
tumor associated calcium signal transducer 2
chr18_+_36544544 1.35 ENST00000591635.5
formin homology 2 domain containing 3
chr1_+_152908538 1.31 ENST00000368764.4
involucrin
chr14_+_75278820 1.29 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr7_-_41703062 1.26 ENST00000242208.5
inhibin subunit beta A
chr4_+_20251896 1.21 ENST00000504154.6
slit guidance ligand 2
chr11_+_62856149 1.20 ENST00000535296.5
solute carrier family 3 member 2
chr15_-_63381835 1.20 ENST00000344366.7
ENST00000178638.8
ENST00000422263.2
carbonic anhydrase 12
chr16_+_57372465 1.14 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr12_-_52291515 1.14 ENST00000615839.1
ENST00000327741.9
keratin 81
chr16_+_57372481 1.13 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr18_+_11752041 1.10 ENST00000423027.8
G protein subunit alpha L
chr1_-_156705742 1.06 ENST00000368221.1
cellular retinoic acid binding protein 2
chr1_-_99766620 1.06 ENST00000646001.2
ferric chelate reductase 1
chr1_-_156705764 1.04 ENST00000621784.4
ENST00000368220.1
cellular retinoic acid binding protein 2
chr6_+_26124161 1.03 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr2_-_121285194 1.03 ENST00000263707.6
transcription factor CP2 like 1
chr22_+_29480211 1.02 ENST00000310624.7
neurofilament heavy
chr12_+_12891554 1.02 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr12_-_53220229 1.01 ENST00000338561.9
retinoic acid receptor gamma
chr5_+_148203024 1.00 ENST00000325630.3
serine peptidase inhibitor Kazal type 6
chr1_-_153041111 0.98 ENST00000360379.4
small proline rich protein 2D
chr1_-_209652329 0.95 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chr1_-_156705575 0.90 ENST00000368222.8
cellular retinoic acid binding protein 2
chr11_+_62856072 0.87 ENST00000377890.6
ENST00000681467.1
ENST00000538084.2
ENST00000681569.1
ENST00000377891.6
ENST00000680725.1
ENST00000377889.6
solute carrier family 3 member 2
chr8_-_133297092 0.87 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr16_+_82035245 0.85 ENST00000199936.9
hydroxysteroid 17-beta dehydrogenase 2
chr15_-_52295792 0.85 ENST00000261839.12
myosin VC
chr19_+_10271093 0.84 ENST00000423829.2
ENST00000588645.1
ENST00000264832.8
intercellular adhesion molecule 1
chr17_-_50468871 0.83 ENST00000508540.6
ENST00000258969.4
chondroadherin
chr15_+_45430579 0.83 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr11_+_62856004 0.82 ENST00000680729.1
solute carrier family 3 member 2
chr17_-_41624541 0.81 ENST00000540235.5
ENST00000311208.13
keratin 17
chr6_-_26216673 0.80 ENST00000541790.3
H2B clustered histone 8
chr17_+_41226648 0.80 ENST00000377721.3
keratin associated protein 9-2
chr1_-_216805367 0.80 ENST00000360012.7
estrogen related receptor gamma
chr1_+_207053229 0.80 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr17_-_41505597 0.79 ENST00000336861.7
ENST00000246635.8
ENST00000587544.5
ENST00000587435.1
keratin 13
chr9_-_122227525 0.75 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr1_-_23559490 0.75 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr3_+_142623386 0.73 ENST00000337777.7
ENST00000497199.5
plastin 1
chr17_+_41237998 0.73 ENST00000254072.7
keratin associated protein 9-8
chr17_+_29246852 0.73 ENST00000225387.8
crystallin beta A1
chr9_+_128149447 0.72 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr17_-_40867200 0.71 ENST00000647902.1
ENST00000251643.5
keratin 12
chr14_-_54902807 0.70 ENST00000543643.6
ENST00000536224.2
ENST00000395514.5
ENST00000491895.7
GTP cyclohydrolase 1
chr6_-_27132750 0.70 ENST00000607124.1
ENST00000339812.3
H2B clustered histone 11
chr3_+_194136138 0.68 ENST00000232424.4
hes family bHLH transcription factor 1
chrX_-_134658450 0.67 ENST00000359237.9
placenta enriched 1
chr4_+_73869385 0.67 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr6_+_112054075 0.65 ENST00000230529.9
ENST00000604763.5
ENST00000368666.7
ENST00000674325.1
ENST00000483439.1
ENST00000409166.5
cellular communication network factor 6
chr4_+_154743993 0.65 ENST00000336356.4
lecithin retinol acyltransferase
chr8_-_24956604 0.62 ENST00000610854.2
neurofilament light
chr3_+_127915469 0.59 ENST00000407609.7
kelch repeat and BTB domain containing 12
chr4_+_75556048 0.55 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr6_-_26123910 0.54 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr12_-_53220377 0.54 ENST00000543726.1
retinoic acid receptor gamma
chrX_+_41688967 0.52 ENST00000378142.9
G protein-coupled receptor 34
chrX_+_41689006 0.52 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr19_+_1071194 0.52 ENST00000543365.5
Rho GTPase activating protein 45
chr13_-_103066411 0.52 ENST00000245312.5
solute carrier family 10 member 2
chrX_-_120311533 0.51 ENST00000440464.5
ENST00000519908.1
transmembrane protein 255A
chr12_-_48570046 0.51 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr9_-_114806031 0.50 ENST00000374045.5
TNF superfamily member 15
chr5_-_58460076 0.49 ENST00000274289.8
ENST00000617412.1
polo like kinase 2
chr17_+_58238426 0.48 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
lactoperoxidase
chr5_-_74866779 0.47 ENST00000510496.5
family with sequence similarity 169 member A
chr5_-_74866958 0.47 ENST00000389156.9
family with sequence similarity 169 member A
chr1_-_59926724 0.47 ENST00000371204.4
cytochrome P450 family 2 subfamily J member 2
chr10_+_119029711 0.47 ENST00000425699.3
nanos C2HC-type zinc finger 1
chr6_+_26021641 0.47 ENST00000617569.2
H4 clustered histone 1
chr6_-_26246996 0.46 ENST00000611444.2
H4 clustered histone 7
chr19_+_16829387 0.46 ENST00000248054.10
ENST00000596802.5
ENST00000379803.5
SIN3 transcription regulator family member B
chr17_-_41124178 0.45 ENST00000394014.2
keratin associated protein 4-12
chr6_-_132714045 0.45 ENST00000367928.5
vanin 1
chr7_+_75395063 0.44 ENST00000450434.5
tripartite motif containing 73
chr1_+_31413187 0.44 ENST00000373709.8
serine incorporator 2
chr16_+_78022538 0.44 ENST00000651443.1
ENST00000299642.10
C-type lectin domain family 3 member A
chr18_-_63661884 0.43 ENST00000332821.8
ENST00000283752.10
serpin family B member 3
chr19_+_12938598 0.43 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr4_-_83114715 0.43 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr16_-_2980282 0.43 ENST00000572619.1
ENST00000574415.5
ENST00000440027.6
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr6_+_7726089 0.42 ENST00000283147.7
bone morphogenetic protein 6
chr16_-_2980406 0.41 ENST00000431515.6
ENST00000574385.5
ENST00000576268.1
ENST00000574730.5
ENST00000262300.13
ENST00000575632.5
ENST00000573944.5
protein kinase, membrane associated tyrosine/threonine 1
chr1_-_6491664 0.41 ENST00000377728.8
ENST00000675093.1
pleckstrin homology and RhoGEF domain containing G5
chr6_+_25726767 0.40 ENST00000274764.5
H2B clustered histone 1
chr19_+_1524068 0.40 ENST00000642079.2
ENST00000454744.7
ENST00000588430.3
polo like kinase 5 (inactive)
chr1_-_27155118 0.40 ENST00000263980.8
solute carrier family 9 member A1
chr2_-_207166818 0.40 ENST00000423015.5
Kruppel like factor 7
chr1_-_165355746 0.39 ENST00000367893.4
LIM homeobox transcription factor 1 alpha
chr12_+_101594849 0.39 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr1_-_42958836 0.39 ENST00000372500.4
ENST00000674765.1
ENST00000460369.3
ENST00000426263.10
solute carrier family 2 member 1
chr7_+_116953482 0.39 ENST00000323984.8
ENST00000417919.5
suppression of tumorigenicity 7
chr2_-_68871382 0.38 ENST00000295379.2
bone morphogenetic protein 10
chr11_+_68684534 0.38 ENST00000265643.4
galanin and GMAP prepropeptide
chr7_+_116953306 0.38 ENST00000265437.9
ENST00000393451.7
suppression of tumorigenicity 7
chr4_+_76074701 0.38 ENST00000355810.9
ENST00000349321.7
ADP-ribosyltransferase 3 (inactive)
chr4_-_109801978 0.38 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr6_-_27831557 0.38 ENST00000611927.2
H4 clustered histone 12
chr7_+_116953238 0.37 ENST00000393446.6
suppression of tumorigenicity 7
chr8_-_17002327 0.37 ENST00000180166.6
fibroblast growth factor 20
chr4_-_152679984 0.37 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr11_-_67647577 0.36 ENST00000529256.1
aminoacylase 3
chr19_-_2051224 0.36 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MAPK interacting serine/threonine kinase 2
chr7_+_116953379 0.36 ENST00000393449.5
suppression of tumorigenicity 7
chr18_+_58196736 0.35 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr11_-_5227063 0.35 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr8_+_2045058 0.34 ENST00000523438.1
myomesin 2
chr7_+_116953514 0.34 ENST00000446490.5
suppression of tumorigenicity 7
chr3_+_127915226 0.34 ENST00000405109.5
kelch repeat and BTB domain containing 12
chr8_+_2045037 0.33 ENST00000262113.9
myomesin 2
chr4_+_122378966 0.33 ENST00000446706.5
ENST00000296513.7
adenosine deaminase domain containing 1
chr14_-_106012390 0.33 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr1_+_152686123 0.33 ENST00000368780.4
late cornified envelope 2B
chr1_-_206921867 0.33 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr7_-_25228485 0.33 ENST00000222674.2
neuropeptide VF precursor
chr22_+_39520553 0.33 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chrX_-_133097095 0.33 ENST00000511190.5
ubiquitin specific peptidase 26
chr17_+_34285734 0.32 ENST00000305869.4
C-C motif chemokine ligand 11
chr3_-_24494875 0.32 ENST00000644321.1
thyroid hormone receptor beta
chr3_+_148865288 0.32 ENST00000296046.4
carboxypeptidase A3
chr19_+_572586 0.32 ENST00000333511.9
ENST00000353555.9
ENST00000680326.1
ENST00000618006.4
ENST00000614867.2
basigin (Ok blood group)
chr3_-_130746760 0.32 ENST00000356763.8
phosphoinositide-3-kinase regulatory subunit 4
chr6_-_41747390 0.31 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
progastricsin
chr8_-_23404076 0.31 ENST00000524168.1
ENST00000389131.8
ENST00000523833.2
ENST00000519243.1
lysyl oxidase like 2
chr1_+_37474572 0.31 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr6_+_110874775 0.31 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr17_-_41382298 0.31 ENST00000394001.3
keratin 34
chr9_+_68302867 0.31 ENST00000342833.4
forkhead box D4 like 3
chr11_+_61362355 0.31 ENST00000542946.1
ENST00000278826.11
transmembrane protein 138
chr8_+_81280527 0.30 ENST00000297258.11
fatty acid binding protein 5
chr7_+_116222804 0.29 ENST00000393481.6
testin LIM domain protein
chr19_+_572529 0.29 ENST00000679472.1
ENST00000680552.1
ENST00000680065.1
ENST00000573216.5
basigin (Ok blood group)
chr17_+_81035122 0.29 ENST00000321280.11
ENST00000575989.5
ENST00000428708.7
ENST00000575712.5
ENST00000575245.5
ENST00000435091.7
ENST00000321300.10
BAR/IMD domain containing adaptor protein 2
chr21_+_33025927 0.28 ENST00000430860.1
ENST00000382357.4
ENST00000333337.3
oligodendrocyte transcription factor 2
chrX_+_85244075 0.28 ENST00000276123.7
zinc finger protein 711
chr3_-_24494791 0.28 ENST00000431815.5
ENST00000356447.9
ENST00000418247.1
ENST00000416420.5
ENST00000396671.7
thyroid hormone receptor beta
chr4_-_99435134 0.28 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_190449782 0.27 ENST00000354905.3
transmembrane protein 207
chr1_-_149842736 0.27 ENST00000369159.2
H2A clustered histone 18
chr5_-_54310545 0.27 ENST00000504924.6
ENST00000620747.4
ENST00000507646.2
ENST00000502271.5
ADP ribosylation factor like GTPase 15
chr7_-_30026617 0.27 ENST00000222803.10
FKBP prolyl isomerase 14
chr7_+_112480853 0.27 ENST00000439068.6
ENST00000312849.4
leucine rich single-pass membrane protein 1
chr1_-_8026283 0.27 ENST00000474874.5
ENST00000469499.5
ENST00000377482.10
ERBB receptor feedback inhibitor 1
chr10_+_116545907 0.26 ENST00000369221.2
pancreatic lipase
chr9_+_273026 0.26 ENST00000682249.1
ENST00000453981.5
ENST00000487230.5
ENST00000469391.5
dedicator of cytokinesis 8
chr7_+_75395629 0.26 ENST00000323819.7
ENST00000430211.5
tripartite motif containing 73
chr19_-_40882226 0.26 ENST00000301146.9
cytochrome P450 family 2 subfamily A member 7
chr8_+_49909783 0.26 ENST00000518864.5
syntrophin gamma 1
chr7_-_72969466 0.25 ENST00000285805.3
tripartite motif containing 74
chr6_+_26216928 0.25 ENST00000303910.4
H2A clustered histone 8
chr10_-_67696115 0.25 ENST00000433211.7
catenin alpha 3
chr4_-_46389351 0.25 ENST00000503806.5
ENST00000356504.5
ENST00000514090.5
ENST00000506961.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr12_-_113966306 0.25 ENST00000545145.6
ENST00000392561.7
ENST00000261741.10
RNA binding motif protein 19
chr3_-_49104745 0.25 ENST00000635194.1
ENST00000306125.12
ENST00000634602.1
ENST00000414533.5
ENST00000635443.1
ENST00000452739.5
ENST00000635231.1
glutaminyl-tRNA synthetase 1
chr10_-_49269 0.25 ENST00000562809.1
ENST00000568866.5
ENST00000561967.1
ENST00000568584.6
tubulin beta 8 class VIII
chr3_+_178419123 0.25 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr11_-_5234475 0.24 ENST00000292901.7
ENST00000650601.1
ENST00000417377.1
hemoglobin subunit delta
chr14_+_21030201 0.24 ENST00000321760.11
ENST00000460647.6
ENST00000530140.6
ENST00000472458.5
tubulin polymerization promoting protein family member 2
chr3_-_197298558 0.24 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr6_-_2903300 0.24 ENST00000380698.5
serpin family B member 9
chr18_-_46964408 0.24 ENST00000676383.1
elongin A3 family member D
chr6_-_27146841 0.24 ENST00000356950.2
H2B clustered histone 12
chr16_-_67483541 0.24 ENST00000290953.3
agouti related neuropeptide
chr1_+_42153399 0.24 ENST00000372581.2
guanylate cyclase activator 2B
chr5_-_43040311 0.24 ENST00000616064.2
annexin A2 receptor
chr1_-_43453792 0.24 ENST00000372434.5
ENST00000486909.1
hydroxypyruvate isomerase (putative)
chr1_-_40862354 0.23 ENST00000372638.4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr19_+_6887560 0.23 ENST00000250572.12
ENST00000381407.9
ENST00000450315.7
ENST00000312053.9
ENST00000381404.8
adhesion G protein-coupled receptor E1
chr1_-_152325232 0.23 ENST00000368799.2
filaggrin
chr17_+_41105332 0.23 ENST00000391415.1
ENST00000617453.1
keratin associated protein 4-9
chr1_-_88891496 0.23 ENST00000448623.5
ENST00000370500.10
ENST00000418217.1
general transcription factor IIB
chr10_-_125881282 0.23 ENST00000284690.4
DEAH-box helicase 32 (putative)
chr14_-_24576240 0.22 ENST00000216336.3
cathepsin G
chr15_-_62165274 0.22 ENST00000380392.4
C2 calcium dependent domain containing 4B
chr2_-_75199511 0.22 ENST00000305249.10
tachykinin receptor 1
chr20_+_23035312 0.22 ENST00000255008.5
somatostatin receptor 4
chr1_+_17249088 0.22 ENST00000375460.3
peptidyl arginine deiminase 3
chr12_+_25052512 0.22 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr1_-_153565535 0.22 ENST00000368707.5
S100 calcium binding protein A2
chr3_-_24494842 0.21 ENST00000646209.2
thyroid hormone receptor beta
chr21_-_30829755 0.21 ENST00000621162.1
keratin associated protein 7-1
chr16_+_71358713 0.21 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.7 2.2 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.5 2.0 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.5 2.9 GO:0060356 leucine import(GO:0060356)
0.4 1.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.4 1.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 1.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.4 1.2 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.4 1.6 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 0.7 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.3 1.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 0.9 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.3 1.8 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.3 1.5 GO:0070295 renal water absorption(GO:0070295)
0.3 0.8 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.3 1.4 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2 3.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 0.7 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.3 GO:0030185 nitric oxide transport(GO:0030185)
0.2 1.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 0.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 0.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 2.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.7 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 1.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.1 GO:1904434 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.4 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 0.4 GO:1903281 regulation of the force of heart contraction by cardiac conduction(GO:0086092) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.1 0.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 16.9 GO:0070268 cornification(GO:0070268)
0.1 0.4 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.8 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.3 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.4 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) regulation of lung blood pressure(GO:0014916) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.4 GO:0002357 defense response to tumor cell(GO:0002357)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 6.4 GO:0006953 acute-phase response(GO:0006953)
0.1 1.0 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.1 GO:0060460 left lung morphogenesis(GO:0060460)
0.1 0.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.2 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.1 0.3 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.3 GO:0035962 response to interleukin-13(GO:0035962)
0.1 0.4 GO:0010612 regulation of cardiac muscle adaptation(GO:0010612) positive regulation of sarcomere organization(GO:0060298) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.2 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.6 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.8 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 1.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.7 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.2 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 1.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.2 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.2 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.0 2.9 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0036404 conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.0 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0002881 microglial cell activation involved in immune response(GO:0002282) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.0 GO:0048058 compound eye corneal lens development(GO:0048058)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 1.3 GO:0035976 AP1 complex(GO:0035976)
0.2 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 0.5 GO:0030849 X chromosome(GO:0000805) autosome(GO:0030849)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 11.0 GO:0045095 keratin filament(GO:0045095)
0.1 3.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.3 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 5.6 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 1.0 GO:0005883 neurofilament(GO:0005883)
0.1 2.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0001939 female pronucleus(GO:0001939)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 3.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0043219 lateral loop(GO:0043219)
0.0 2.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.3 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 3.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0033167 ARC complex(GO:0033167)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 2.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.0 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 0.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 1.5 GO:0015254 glycerol channel activity(GO:0015254)
0.2 4.2 GO:0019841 retinol binding(GO:0019841)
0.2 2.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 6.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.2 GO:0048495 laminin-1 binding(GO:0043237) Roundabout binding(GO:0048495)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 2.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.2 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.1 0.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.9 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.7 GO:0008009 chemokine activity(GO:0008009)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 8.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.7 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 1.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 5.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 12.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 6.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin