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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TFAP2B

Z-value: 1.51

Motif logo

Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.13 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg38_v1_chr6_+_50818857_508188770.695.6e-02Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153615858 1.90 ENST00000476873.5
S100 calcium binding protein A14
chr1_+_160400543 1.72 ENST00000368061.3
VANGL planar cell polarity protein 2
chr17_-_41521719 1.63 ENST00000393976.6
keratin 15
chr16_+_22814154 1.23 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr16_+_68644988 1.20 ENST00000429102.6
cadherin 3
chr16_+_68645290 1.10 ENST00000264012.9
cadherin 3
chr12_-_52520371 1.09 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
keratin 5
chr6_+_54846735 1.08 ENST00000306858.8
family with sequence similarity 83 member B
chr20_+_63696643 0.97 ENST00000369996.3
TNF receptor superfamily member 6b
chr19_-_19628197 0.94 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr19_-_55149193 0.82 ENST00000587758.5
ENST00000588981.6
ENST00000356783.9
ENST00000291901.12
ENST00000588426.5
ENST00000536926.5
ENST00000588147.5
troponin T1, slow skeletal type
chr14_+_64704380 0.82 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr2_+_85133376 0.80 ENST00000282111.4
transcription factor 7 like 1
chr8_-_22131043 0.79 ENST00000312841.9
HR lysine demethylase and nuclear receptor corepressor
chr1_+_233327710 0.76 ENST00000366624.8
mitogen-activated protein kinase kinase kinase 21
chr11_-_120138104 0.76 ENST00000341846.10
tripartite motif containing 29
chr8_-_22131003 0.76 ENST00000381418.9
HR lysine demethylase and nuclear receptor corepressor
chr19_+_7645895 0.73 ENST00000602355.1
syntaxin binding protein 2
chr14_+_94174284 0.65 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chr7_+_16753731 0.62 ENST00000262067.5
tetraspanin 13
chr12_-_101830671 0.61 ENST00000549165.1
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr6_-_138107412 0.61 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr1_+_65147830 0.61 ENST00000395334.6
adenylate kinase 4
chr16_+_67199509 0.60 ENST00000477898.5
engulfment and cell motility 3
chr1_+_65148169 0.60 ENST00000327299.8
adenylate kinase 4
chr21_+_17513003 0.59 ENST00000284878.12
ENST00000400166.5
CXADR Ig-like cell adhesion molecule
chr16_+_67199104 0.58 ENST00000360833.6
ENST00000652269.1
ENST00000393997.8
engulfment and cell motility 3
chr1_+_206507520 0.58 ENST00000579436.7
Ras association domain family member 5
chr16_+_67431112 0.57 ENST00000326152.6
hydroxysteroid 11-beta dehydrogenase 2
chr15_+_40252888 0.57 ENST00000559139.5
ENST00000560669.5
ENST00000542403.3
p21 (RAC1) activated kinase 6
chr7_-_143408848 0.57 ENST00000275815.4
EPH receptor A1
chr1_-_26960413 0.55 ENST00000320567.6
keratinocyte differentiation factor 1
chr1_-_26960369 0.54 ENST00000616918.1
keratinocyte differentiation factor 1
chr1_+_206507546 0.54 ENST00000580449.5
ENST00000581503.6
Ras association domain family member 5
chr1_+_31576485 0.53 ENST00000457433.6
ENST00000271064.12
tubulointerstitial nephritis antigen like 1
chr2_+_120013111 0.53 ENST00000331393.8
ENST00000443124.5
erythrocyte membrane protein band 4.1 like 5
chr3_+_141231770 0.53 ENST00000286353.9
ENST00000502783.5
ENST00000393010.6
ENST00000514680.5
2-phosphoxylose phosphatase 1
chr1_+_65147514 0.53 ENST00000545314.5
adenylate kinase 4
chr8_+_119208322 0.52 ENST00000614891.5
mal, T cell differentiation protein 2
chr16_+_2964216 0.52 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
kringle containing transmembrane protein 2
chr5_+_36608146 0.51 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr20_+_9069076 0.51 ENST00000378473.9
phospholipase C beta 4
chr20_-_52191697 0.51 ENST00000361387.6
ZFP64 zinc finger protein
chr10_-_47384261 0.49 ENST00000591025.1
ENST00000585316.3
zinc finger protein 488
chr22_+_44677044 0.49 ENST00000006251.11
proline rich 5
chr22_+_44677077 0.49 ENST00000403581.5
proline rich 5
chr22_+_44676808 0.49 ENST00000624862.3
proline rich 5
chr12_-_89352487 0.48 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr19_+_7637099 0.48 ENST00000595950.5
ENST00000221283.10
ENST00000441779.6
ENST00000414284.6
syntaxin binding protein 2
chr21_+_42219123 0.48 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr21_+_42219111 0.45 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr1_+_32741779 0.44 ENST00000401073.7
KIAA1522
chr14_+_93927259 0.44 ENST00000556222.1
ENST00000554404.1
family with sequence similarity 181 member A
chr1_+_152908538 0.44 ENST00000368764.4
involucrin
chr5_-_151224069 0.43 ENST00000355417.7
coiled-coil domain containing 69
chr13_-_75482151 0.43 ENST00000377636.8
TBC1 domain family member 4
chr17_-_4560564 0.43 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
gamma-glutamyltransferase 6
chr12_-_89352395 0.43 ENST00000308385.6
dual specificity phosphatase 6
chr16_+_81444799 0.43 ENST00000537098.8
c-Maf inducing protein
chr13_-_75482114 0.42 ENST00000377625.6
ENST00000431480.6
TBC1 domain family member 4
chr14_+_92513766 0.42 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chr1_+_149899618 0.40 ENST00000369150.1
bolA family member 1
chr8_-_142786530 0.40 ENST00000301263.5
lymphocyte antigen 6 family member D
chr19_-_11578937 0.40 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
acid phosphatase 5, tartrate resistant
chr16_+_2817230 0.40 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr8_+_122781621 0.39 ENST00000314393.6
zinc fingers and homeoboxes 2
chr4_+_151409169 0.39 ENST00000435205.6
family with sequence similarity 160 member A1
chr1_+_81800906 0.38 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr20_+_6767678 0.38 ENST00000378827.5
bone morphogenetic protein 2
chrX_-_79367307 0.38 ENST00000373298.7
integral membrane protein 2A
chr22_+_50674879 0.38 ENST00000262795.6
SH3 and multiple ankyrin repeat domains 3
chr9_+_121651594 0.38 ENST00000408936.7
DAB2 interacting protein
chr11_-_7674206 0.36 ENST00000533558.5
ENST00000527542.5
cytochrome b5 reductase 2
chr8_-_143572748 0.36 ENST00000529971.1
ENST00000398882.8
maestro heat like repeat family member 6
chr19_+_1067493 0.36 ENST00000586866.5
Rho GTPase activating protein 45
chr11_-_7673485 0.35 ENST00000299498.11
cytochrome b5 reductase 2
chrX_-_154805386 0.35 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
membrane palmitoylated protein 1
chr19_+_35138993 0.35 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr2_-_73284431 0.35 ENST00000521871.5
ENST00000520530.3
F-box protein 41
chr12_-_101830799 0.35 ENST00000549940.5
ENST00000392919.4
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr1_-_23559490 0.34 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr5_-_175444132 0.34 ENST00000393752.3
dopamine receptor D1
chr1_+_45326869 0.34 ENST00000334815.6
4-hydroxyphenylpyruvate dioxygenase like
chr12_+_6951345 0.33 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
protein tyrosine phosphatase non-receptor type 6
chr19_+_1067144 0.33 ENST00000313093.7
Rho GTPase activating protein 45
chr7_-_151632330 0.33 ENST00000418337.6
protein kinase AMP-activated non-catalytic subunit gamma 2
chrX_-_154805516 0.33 ENST00000413259.7
membrane palmitoylated protein 1
chr12_+_6951271 0.33 ENST00000456013.5
protein tyrosine phosphatase non-receptor type 6
chr17_-_41786688 0.32 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr16_+_2817180 0.32 ENST00000450020.7
serine protease 21
chr3_+_13549117 0.32 ENST00000404922.8
fibulin 2
chr5_+_142771119 0.32 ENST00000642734.1
Rho GTPase activating protein 26
chr19_+_1067272 0.32 ENST00000590214.5
Rho GTPase activating protein 45
chr1_+_54548217 0.32 ENST00000343744.7
ENST00000371316.3
acyl-CoA thioesterase 11
chr17_+_1742836 0.31 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
serpin family F member 2
chr1_-_147773341 0.30 ENST00000430508.1
ENST00000621517.1
gap junction protein alpha 5
chr11_+_59172116 0.30 ENST00000227451.4
deltex E3 ubiquitin ligase 4
chr12_-_31729010 0.30 ENST00000537562.5
ENST00000537960.5
ENST00000281471.11
ENST00000536761.5
ENST00000542781.5
ENST00000457428.6
antagonist of mitotic exit network 1 homolog
chr1_+_153774210 0.30 ENST00000271857.6
solute carrier family 27 member 3
chr3_-_185499022 0.30 ENST00000421852.6
transmembrane protein 41A
chr3_+_13549136 0.29 ENST00000295760.11
fibulin 2
chr5_-_135034212 0.29 ENST00000265340.12
paired like homeodomain 1
chr16_+_81645352 0.29 ENST00000398040.8
c-Maf inducing protein
chr1_+_32251239 0.29 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK proto-oncogene, Src family tyrosine kinase
chr12_+_6199715 0.29 ENST00000382518.6
ENST00000642746.1
ENST00000538834.6
CD9 molecule
chr14_-_93115812 0.28 ENST00000553452.5
inositol-tetrakisphosphate 1-kinase
chr11_+_63839086 0.28 ENST00000350490.11
ENST00000402010.8
microtubule affinity regulating kinase 2
chr11_+_63839173 0.28 ENST00000502399.7
ENST00000425897.3
ENST00000513765.7
ENST00000679216.1
microtubule affinity regulating kinase 2
chr3_-_197029775 0.28 ENST00000439320.1
ENST00000296351.8
ENST00000296350.10
melanotransferrin
chr1_+_149899561 0.28 ENST00000369152.6
bolA family member 1
chrX_-_386900 0.27 ENST00000390665.9
protein phosphatase 2 regulatory subunit B''beta
chr15_-_79090760 0.27 ENST00000419573.7
ENST00000558480.7
Ras protein specific guanine nucleotide releasing factor 1
chr1_+_7784411 0.27 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chrX_+_132023294 0.27 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr1_-_24964984 0.27 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr19_-_42220109 0.27 ENST00000595337.5
death effector domain containing 2
chr19_+_37907200 0.26 ENST00000222345.11
signal induced proliferation associated 1 like 3
chr19_+_39498938 0.26 ENST00000356433.10
ENST00000596614.5
ENST00000205143.4
delta like canonical Notch ligand 3
chr3_-_125120813 0.26 ENST00000430155.6
solute carrier family 12 member 8
chr9_+_114155526 0.26 ENST00000356083.8
collagen type XXVII alpha 1 chain
chr22_+_31082860 0.26 ENST00000619644.4
smoothelin
chr12_+_112418976 0.25 ENST00000635625.1
protein tyrosine phosphatase non-receptor type 11
chr1_+_15153698 0.25 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
transmembrane protein 51
chr6_-_3457018 0.25 ENST00000436008.6
ENST00000406686.8
solute carrier family 22 member 23
chr2_-_207165923 0.25 ENST00000309446.11
Kruppel like factor 7
chr22_-_46537593 0.24 ENST00000262738.9
ENST00000674500.2
cadherin EGF LAG seven-pass G-type receptor 1
chr5_+_132073782 0.24 ENST00000296871.4
colony stimulating factor 2
chr2_+_96760857 0.24 ENST00000377075.3
cyclin and CBS domain divalent metal cation transport mediator 4
chr20_+_1894733 0.24 ENST00000356025.7
signal regulatory protein alpha
chrX_-_15854743 0.24 ENST00000450644.2
adaptor related protein complex 1 subunit sigma 2
chr12_-_95548213 0.24 ENST00000537435.2
ubiquitin specific peptidase 44
chr16_+_88706458 0.24 ENST00000312060.9
ENST00000453996.7
ENST00000567949.5
ENST00000564921.1
cytosolic thiouridylase subunit 2
chr4_+_1721470 0.23 ENST00000612220.5
ENST00000313288.9
transforming acidic coiled-coil containing protein 3
chr6_+_33621313 0.23 ENST00000605930.3
inositol 1,4,5-trisphosphate receptor type 3
chr14_+_24070837 0.23 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr6_-_34696733 0.23 ENST00000374023.8
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr19_+_10718114 0.23 ENST00000408974.8
dynamin 2
chr8_-_8893548 0.23 ENST00000276282.7
malignant fibrous histiocytoma amplified sequence 1
chr5_+_150357629 0.23 ENST00000650162.1
ENST00000377797.7
ENST00000445265.6
ENST00000323668.11
ENST00000643257.2
ENST00000646961.1
ENST00000513538.2
ENST00000439160.6
ENST00000394269.7
ENST00000427724.7
ENST00000504761.6
ENST00000513346.5
ENST00000515516.1
treacle ribosome biogenesis factor 1
chr16_-_66925526 0.23 ENST00000299759.11
ENST00000420652.5
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr20_+_1894462 0.22 ENST00000622179.4
signal regulatory protein alpha
chr1_+_155208727 0.22 ENST00000316721.8
metaxin 1
chr2_+_200440649 0.22 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr3_-_52409783 0.22 ENST00000470173.1
ENST00000296288.9
ENST00000460680.6
BRCA1 associated protein 1
chr4_-_83109843 0.22 ENST00000411416.6
placenta associated 8
chr14_+_94174334 0.22 ENST00000328839.3
protein phosphatase 4 regulatory subunit 4
chr4_-_1721313 0.22 ENST00000382936.8
ENST00000536901.1
ENST00000303277.6
transmembrane protein 129, E3 ubiquitin ligase
chr17_-_7857461 0.22 ENST00000575771.6
ENST00000575071.5
N-alpha-acetyltransferase 38, NatC auxiliary subunit
chr3_+_125969172 0.21 ENST00000514116.6
ENST00000513830.5
rhophilin associated tail protein 1B
chr5_+_141637398 0.21 ENST00000518856.1
RELT like 2
chrX_+_132023580 0.21 ENST00000496850.1
serine/threonine kinase 26
chr12_-_101830926 0.21 ENST00000299314.12
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr16_-_88706262 0.21 ENST00000562544.1
ring finger protein 166
chr8_+_144104512 0.21 ENST00000534585.5
MAF1 homolog, negative regulator of RNA polymerase III
chr7_+_98211431 0.21 ENST00000609256.2
basic helix-loop-helix family member a15
chr22_+_21632751 0.21 ENST00000292779.4
coiled-coil domain containing 116
chr16_-_88706353 0.20 ENST00000567844.1
ENST00000312838.9
ring finger protein 166
chr22_-_42270587 0.20 ENST00000677622.1
transcription factor 20
chr5_+_141636941 0.20 ENST00000444782.5
ENST00000297164.8
ENST00000521367.5
RELT like 2
chr2_+_202634960 0.20 ENST00000392238.3
family with sequence similarity 117 member B
chr1_-_1919258 0.20 ENST00000378598.4
ENST00000416272.1
ENST00000310991.8
transmembrane protein 52
chr16_+_23678863 0.20 ENST00000300093.9
polo like kinase 1
chr5_+_56815534 0.20 ENST00000399503.4
mitogen-activated protein kinase kinase kinase 1
chr1_+_155209213 0.20 ENST00000609421.1
metaxin 1
chr1_+_155208690 0.20 ENST00000368376.8
metaxin 1
chr21_-_46155567 0.20 ENST00000291670.9
ENST00000397748.5
ENST00000397743.1
ENST00000397746.8
formimidoyltransferase cyclodeaminase
chr12_-_95548837 0.19 ENST00000393091.6
ubiquitin specific peptidase 44
chr8_-_141001217 0.19 ENST00000522684.5
ENST00000524357.5
ENST00000521332.5
ENST00000524040.5
ENST00000519881.5
ENST00000520045.5
protein tyrosine kinase 2
chr3_+_125969152 0.19 ENST00000251776.8
ENST00000504401.1
rhophilin associated tail protein 1B
chr14_-_21025000 0.19 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr2_+_101252867 0.19 ENST00000289382.8
CCR4-NOT transcription complex subunit 11
chr1_+_17249088 0.19 ENST00000375460.3
peptidyl arginine deiminase 3
chr1_+_19644284 0.19 ENST00000375136.8
NBL1, DAN family BMP antagonist
chr12_-_113471851 0.19 ENST00000261731.4
LIM homeobox 5
chr12_-_14961610 0.18 ENST00000542276.1
Rho GDP dissociation inhibitor beta
chr1_+_19643708 0.18 ENST00000439664.5
ENST00000621723.4
NBL1, DAN family BMP antagonist
chr12_-_14961256 0.18 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr12_+_19129779 0.18 ENST00000539256.5
ENST00000299275.10
ENST00000538714.5
pleckstrin homology domain containing A5
chr8_+_31640358 0.18 ENST00000523534.5
neuregulin 1
chrX_+_49058966 0.18 ENST00000496529.6
ENST00000606812.5
ENST00000603986.6
ENST00000536628.3
coiled-coil domain containing 120
chr7_+_150801695 0.18 ENST00000475536.5
ENST00000468689.2
transmembrane protein 176A
chr1_+_42456090 0.18 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr11_-_68213577 0.17 ENST00000402789.5
ENST00000402185.6
ENST00000458496.1
lysine methyltransferase 5B
chr12_-_14961559 0.17 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chrX_+_153411472 0.17 ENST00000338647.7
ZFP92 zinc finger protein
chr10_-_97633485 0.17 ENST00000370635.3
ENST00000478953.1
ENST00000307450.11
MORN repeat containing 4
chr5_+_62412755 0.17 ENST00000325324.11
importin 11
chr19_+_5805018 0.17 ENST00000303212.3
neurturin
chr7_+_150801522 0.17 ENST00000461345.5
transmembrane protein 176A
chr19_-_16627943 0.17 ENST00000611692.4
mediator complex subunit 26
chr6_-_33298909 0.17 ENST00000497454.6
ral guanine nucleotide dissociation stimulator like 2
chr18_+_3449817 0.17 ENST00000407501.6
TGFB induced factor homeobox 1
chr1_+_28887072 0.17 ENST00000647103.1
ENST00000642937.2
ENST00000646189.1
ENST00000644342.1
ENST00000373800.7
ENST00000649717.1
erythrocyte membrane protein band 4.1
chr12_+_112418928 0.16 ENST00000351677.7
ENST00000639857.1
protein tyrosine phosphatase non-receptor type 11
chr7_-_150801325 0.16 ENST00000447204.6
transmembrane protein 176B
chr19_+_19033575 0.16 ENST00000392335.6
ENST00000537263.5
ENST00000540707.5
ENST00000535612.6
ENST00000541725.5
ENST00000269932.10
ENST00000546344.5
ENST00000540792.5
ENST00000536098.5
ENST00000541898.5
armadillo repeat containing 6
chr3_+_41199462 0.16 ENST00000647264.1
ENST00000645900.1
ENST00000646174.1
ENST00000643992.1
ENST00000647390.1
ENST00000642886.1
catenin beta 1
chr17_-_45425620 0.16 ENST00000376922.6
Rho GTPase activating protein 27
chr2_-_236168376 0.16 ENST00000306318.5
gastrulation brain homeobox 2
chr17_-_17496387 0.16 ENST00000225688.4
ENST00000579152.1
ras related dexamethasone induced 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.6 1.7 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.3 0.9 GO:0009720 detection of hormone stimulus(GO:0009720)
0.3 1.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 0.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.9 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.2 1.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 0.9 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 1.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.4 GO:0060128 regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.5 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.5 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.9 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0035106 operant conditioning(GO:0035106)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.3 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.4 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.2 GO:1900166 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 0.2 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0002934 desmosome organization(GO:0002934)
0.1 0.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.4 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.5 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 1.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:1900163 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.0 0.1 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0046684 corticospinal neuron axon guidance(GO:0021966) response to pyrethroid(GO:0046684)
0.0 0.7 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.5 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.0 GO:1903537 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 2.1 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.3 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0001827 inner cell mass cell fate commitment(GO:0001827) germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0060187 cell pole(GO:0060187)
0.1 1.2 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 3.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 1.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.9 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0052835 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.3 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.1 1.1 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.9 GO:0071253 connexin binding(GO:0071253)
0.1 0.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.1 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.2 GO:0070404 NADH binding(GO:0070404)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 2.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 1.9 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176) ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor