ISMARA results: TFDP1

Project

avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation

Downloads

Results for TFDP1

Z-value: 0.79

Motif logo

Transcription factors associated with TFDP1

Gene Symbol	Gene ID	Gene Info
TFDP1 Ensembl NCBI GeneCards UniProt	ENSG00000198176.13	transcription factor Dp-1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TFDP1	hg38_v1_chr13_+_113584683_113584762	0.03	9.4e-01	Click!

Activity profile of TFDP1 motif

Sorted Z-values of TFDP1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_+_37170133 Show fit	1.40	ENST00000373509.6	PIM1 Ensembl NCBI GeneCards UniProt Show fit	Pim-1 proto-oncogene, serine/threonine kinase
chr15_+_80695277 Show fit	1.21	ENST00000258884.5 ENST00000558464.1	ABHD17C Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 17C, depalmitoylase
chr5_+_53480619 Show fit	1.16	ENST00000396947.7 ENST00000256759.8	FST Ensembl NCBI GeneCards UniProt Show fit	follistatin
chr1_+_4654732 Show fit	1.15	ENST00000378190.7	AJAP1 Ensembl NCBI GeneCards UniProt Show fit	adherens junctions associated protein 1
chr12_+_122021850 Show fit	1.08	ENST00000261822.5	BCL7A Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL7A
chr19_+_33796268 Show fit	1.02	ENST00000587559.5 ENST00000588637.5	KCTD15 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 15
chr8_+_60678705 Show fit	1.00	ENST00000423902.7	CHD7 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 7
chr7_+_69598465 Show fit	0.86	ENST00000342771.10	AUTS2 Ensembl NCBI GeneCards UniProt Show fit	activator of transcription and developmental regulator AUTS2
chr1_+_26529745 Show fit	0.84	ENST00000374168.7 ENST00000374166.8	RPS6KA1 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A1
chr7_-_44325653 Show fit	0.83	ENST00000440254.6	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II beta

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of TFDP1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.5	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.4	2.4	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.0	2.4	GO:0051028	mRNA transport(GO:0051028)
0.3	1.6	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.2	1.6	GO:2000620	innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5	1.4	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
0.2	1.4	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1	1.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.3	1.3	GO:0003408	optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344)
0.2	1.3	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)

Showing 1 to 10 of 556 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.2	2.4	GO:0061689	tricellular tight junction(GO:0061689)
0.0	2.3	GO:0070160	occluding junction(GO:0070160)
0.1	2.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.3	1.6	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2	1.5	GO:0097452	GAIT complex(GO:0097452)
0.0	1.5	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	1.3	GO:0031143	pseudopodium(GO:0031143)
0.0	1.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	1.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)

Showing 1 to 10 of 180 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.1	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	2.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	1.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	1.8	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	1.6	GO:0008143	poly(A) binding(GO:0008143)
0.0	1.6	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	1.4	GO:0045499	chemorepellent activity(GO:0045499)
0.0	1.4	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	1.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	1.4	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)

Showing 1 to 10 of 309 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.5	PID LKB1 PATHWAY	LKB1 signaling events
0.0	2.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	2.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	2.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	2.1	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.9	PID ATR PATHWAY	ATR signaling pathway
0.1	1.8	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.7	PID BMP PATHWAY	BMP receptor signaling
0.0	1.6	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	1.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein

Showing 1 to 10 of 48 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	1.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	1.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	1.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets

Showing 1 to 10 of 93 entries

Results for TFDP1

Z-value: 0.79

Motif logo

Transcription factors associated with TFDP1

Activity-expression correlation:

Activity profile of TFDP1 motif

Sorted Z-values of TFDP1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TFDP1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: