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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TLX2

Z-value: 1.08

Motif logo

Transcription factors associated with TLX2

Gene Symbol Gene ID Gene Info
ENSG00000115297.11 T cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TLX2hg38_v1_chr2_+_74513441_74513559,
hg38_v1_chr2_+_74514442_74514494
-0.581.3e-01Click!

Activity profile of TLX2 motif

Sorted Z-values of TLX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_121873152 1.35 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
protein tyrosine phosphatase receptor type Z1
chr7_+_121873089 1.30 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr1_+_86424154 1.25 ENST00000370565.5
chloride channel accessory 2
chr10_+_80413817 1.01 ENST00000372187.9
peroxiredoxin like 2A
chr1_-_153390976 0.89 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr10_+_46375645 0.89 ENST00000622769.4
annexin A8 like 1
chr8_+_31640358 0.87 ENST00000523534.5
neuregulin 1
chr19_-_14979676 0.81 ENST00000598504.5
ENST00000597262.1
solute carrier family 1 member 6
chr6_-_138107412 0.77 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr10_-_47484081 0.76 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
annexin A8
chr16_-_68236069 0.74 ENST00000473183.7
ENST00000565858.5
epithelial splicing regulatory protein 2
chr10_-_47484133 0.67 ENST00000583911.5
ENST00000611843.4
annexin A8
chr12_+_100794769 0.65 ENST00000392977.8
ENST00000546991.1
ENST00000392979.7
anoctamin 4
chr1_+_153357846 0.64 ENST00000368738.4
S100 calcium binding protein A9
chr18_+_31376777 0.64 ENST00000308128.9
ENST00000359747.4
desmoglein 4
chr10_+_46375619 0.63 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr16_+_57372481 0.63 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr12_-_95217373 0.63 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FYVE, RhoGEF and PH domain containing 6
chr5_+_132073782 0.63 ENST00000296871.4
colony stimulating factor 2
chr14_+_64704380 0.62 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr12_+_12891554 0.62 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr1_+_94820595 0.62 ENST00000467909.5
ENST00000422520.6
ENST00000532427.5
solute carrier family 44 member 3
chr9_+_69325168 0.62 ENST00000303068.14
family with sequence similarity 189 member A2
chr16_+_57372465 0.62 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr2_+_112095189 0.62 ENST00000649734.1
transmembrane protein 87B
chr5_+_69415382 0.60 ENST00000512803.5
MARVEL domain containing 2
chr5_+_69415065 0.59 ENST00000647531.1
ENST00000645446.1
ENST00000325631.10
ENST00000454295.6
MARVEL domain containing 2
chr20_-_14337602 0.58 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3
chr11_+_62856004 0.58 ENST00000680729.1
solute carrier family 3 member 2
chr5_+_36606355 0.57 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr1_+_61952283 0.55 ENST00000307297.8
PATJ crumbs cell polarity complex component
chr1_-_24143112 0.55 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr8_+_55879818 0.54 ENST00000520220.6
ENST00000519728.6
LYN proto-oncogene, Src family tyrosine kinase
chr1_+_61952036 0.54 ENST00000646453.1
ENST00000635137.1
PATJ crumbs cell polarity complex component
chr1_+_151511376 0.53 ENST00000427934.2
ENST00000271636.12
cingulin
chr2_-_215138603 0.52 ENST00000272895.12
ATP binding cassette subfamily A member 12
chr7_-_32071397 0.50 ENST00000396184.7
ENST00000396189.2
ENST00000321453.12
phosphodiesterase 1C
chr1_-_6466138 0.50 ENST00000356876.8
ENST00000377782.7
ENST00000351959.9
TNF receptor superfamily member 25
chr16_+_5071806 0.50 ENST00000684335.1
ENST00000684190.1
ENST00000586840.1
ENST00000262374.10
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
chr1_+_152908538 0.50 ENST00000368764.4
involucrin
chr12_+_56338873 0.49 ENST00000228534.6
interleukin 23 subunit alpha
chr3_-_149333407 0.49 ENST00000470080.5
transmembrane 4 L six family member 18
chr1_+_152514474 0.48 ENST00000368790.4
cysteine rich C-terminal 1
chr18_+_31498168 0.47 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr17_-_48590231 0.47 ENST00000476342.1
ENST00000460160.5
ENST00000498678.6
ENST00000472863.5
homeobox B3
chr19_+_49581304 0.46 ENST00000246794.10
proline rich and Gla domain 2
chr11_+_1839452 0.45 ENST00000381906.5
troponin I2, fast skeletal type
chr12_-_70637405 0.44 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr6_+_106098933 0.43 ENST00000369089.3
PR/SET domain 1
chr22_+_31082860 0.43 ENST00000619644.4
smoothelin
chr11_+_35139162 0.42 ENST00000415148.6
ENST00000263398.11
ENST00000428726.8
ENST00000526669.6
ENST00000433892.6
ENST00000525211.6
ENST00000278386.10
ENST00000434472.6
ENST00000352818.8
ENST00000442151.6
CD44 molecule (Indian blood group)
chrX_-_31178220 0.42 ENST00000681026.1
dystrophin
chr7_-_22500152 0.42 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr3_+_122077850 0.42 ENST00000482356.5
ENST00000393627.6
CD86 molecule
chrX_-_31178149 0.42 ENST00000679437.1
dystrophin
chr2_+_17540670 0.42 ENST00000451533.5
ENST00000295156.9
visinin like 1
chr3_-_183162726 0.41 ENST00000265598.8
lysosomal associated membrane protein 3
chr16_+_82035245 0.40 ENST00000199936.9
hydroxysteroid 17-beta dehydrogenase 2
chrX_-_15664798 0.40 ENST00000380342.4
collectrin, amino acid transport regulator
chr12_+_48978313 0.37 ENST00000293549.4
Wnt family member 1
chr2_+_102311502 0.37 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr15_-_34210011 0.36 ENST00000557877.5
katanin regulatory subunit B1 like 1
chr1_-_6466107 0.36 ENST00000348333.7
ENST00000351748.7
TNF receptor superfamily member 25
chr12_+_6385119 0.35 ENST00000541102.1
lymphotoxin beta receptor
chr17_-_78132407 0.35 ENST00000322914.7
transmembrane channel like 6
chr1_+_9651723 0.35 ENST00000377346.9
ENST00000536656.5
ENST00000628140.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr4_+_41935423 0.34 ENST00000504986.6
transmembrane protein 33
chr8_-_104589241 0.33 ENST00000276654.10
LDL receptor related protein 12
chr8_-_104588998 0.33 ENST00000424843.6
LDL receptor related protein 12
chr7_-_105522264 0.33 ENST00000469408.6
pseudouridine synthase 7
chr11_+_67391975 0.33 ENST00000307980.7
RAD9 checkpoint clamp component A
chr19_+_676385 0.33 ENST00000166139.9
follistatin like 3
chr1_+_24319511 0.32 ENST00000356046.6
grainyhead like transcription factor 3
chr19_+_38930916 0.32 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
mitochondrial ribosomal protein S12
chr12_-_120325936 0.32 ENST00000549767.1
phospholipase A2 group IB
chr7_-_105522204 0.32 ENST00000356362.6
pseudouridine synthase 7
chr6_-_11044275 0.32 ENST00000354666.4
ELOVL fatty acid elongase 2
chr9_+_35673917 0.32 ENST00000617161.1
ENST00000378357.9
carbonic anhydrase 9
chr10_-_102120246 0.32 ENST00000425280.2
LIM domain binding 1
chr12_+_8992029 0.32 ENST00000543895.1
killer cell lectin like receptor G1
chr1_-_202967229 0.32 ENST00000367249.9
cytochrome b5 reductase 1
chr6_+_116370938 0.31 ENST00000644252.3
ENST00000646710.1
ENST00000359564.3
dermatan sulfate epimerase
chr12_+_34022462 0.31 ENST00000538927.1
ENST00000266483.7
ALG10 alpha-1,2-glucosyltransferase
chr3_+_50155024 0.31 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr1_+_24319342 0.31 ENST00000361548.9
grainyhead like transcription factor 3
chr5_-_177409535 0.31 ENST00000253496.4
coagulation factor XII
chr4_+_41935114 0.30 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
transmembrane protein 33
chr7_+_24573415 0.30 ENST00000409761.5
ENST00000222644.10
ENST00000396475.6
membrane palmitoylated protein 6
chr22_+_31081310 0.30 ENST00000426927.5
ENST00000482444.5
ENST00000440425.5
ENST00000333137.12
ENST00000358743.5
ENST00000347557.6
smoothelin
chr6_-_118935146 0.29 ENST00000619706.5
ENST00000316316.10
minichromosome maintenance 9 homologous recombination repair factor
chr1_-_153057504 0.29 ENST00000392653.3
small proline rich protein 2A
chr16_-_88785210 0.29 ENST00000301015.14
piezo type mechanosensitive ion channel component 1
chr1_-_10982037 0.29 ENST00000377004.8
chromosome 1 open reading frame 127
chr13_-_49691434 0.29 ENST00000378270.5
ENST00000378284.6
ENST00000378272.9
ENST00000378268.1
ENST00000242827.11
EBP like
chr9_+_2622053 0.29 ENST00000681306.1
ENST00000681618.1
very low density lipoprotein receptor
chr12_+_19205294 0.29 ENST00000424268.5
pleckstrin homology domain containing A5
chr8_+_79611727 0.29 ENST00000518491.1
stathmin 2
chr4_-_164383986 0.29 ENST00000507270.5
ENST00000514618.5
ENST00000503008.5
membrane associated ring-CH-type finger 1
chr4_-_67545464 0.29 ENST00000273853.11
centromere protein C
chr22_-_30529163 0.28 ENST00000437871.1
SEC14 like lipid binding 6
chr3_+_122077776 0.28 ENST00000264468.9
CD86 molecule
chr2_-_62506136 0.28 ENST00000335390.6
transmembrane protein 17
chr3_+_122055355 0.28 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr11_-_65134429 0.28 ENST00000526060.5
ENST00000307289.10
ENST00000528487.1
synoviolin 1
chr11_-_65134507 0.27 ENST00000377190.8
ENST00000294256.12
synoviolin 1
chr9_+_2621766 0.27 ENST00000382100.8
very low density lipoprotein receptor
chr7_+_31687208 0.26 ENST00000409146.3
ENST00000342032.8
protein phosphatase 1 regulatory subunit 17
chr10_+_46375721 0.26 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
novel transcript
annexin A8 like 1
chr2_-_238288600 0.26 ENST00000254657.8
period circadian regulator 2
chr7_+_75915148 0.26 ENST00000461988.6
ENST00000421059.1
ENST00000394893.5
ENST00000412521.5
ENST00000414186.5
cytochrome p450 oxidoreductase
chr11_-_1036706 0.26 ENST00000421673.7
mucin 6, oligomeric mucus/gel-forming
chr4_+_17810945 0.26 ENST00000251496.7
non-SMC condensin I complex subunit G
chr15_-_82262660 0.25 ENST00000557844.1
ENST00000359445.7
ENST00000268206.12
elongation factor like GTPase 1
chr12_+_31959406 0.25 ENST00000540924.5
ENST00000312561.9
retroelement silencing factor 1
chr3_+_119173564 0.25 ENST00000264234.8
ENST00000479520.5
ENST00000494855.5
uroplakin 1B
chr1_+_205504592 0.25 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chr12_-_54391270 0.25 ENST00000352268.10
ENST00000549962.5
ENST00000338010.9
ENST00000550774.5
zinc finger protein 385A
chr7_-_33040893 0.25 ENST00000643244.1
ENST00000409467.6
ENST00000449201.5
5'-nucleotidase, cytosolic IIIA
chr12_-_109833373 0.25 ENST00000261740.7
transient receptor potential cation channel subfamily V member 4
chr3_+_184380207 0.24 ENST00000450923.5
ENST00000348986.3
chordin
chr2_+_203936755 0.24 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr21_+_42219123 0.24 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr5_-_16916400 0.24 ENST00000513882.5
myosin X
chr16_-_72172135 0.24 ENST00000537465.5
ENST00000237353.15
polyamine modulated factor 1 binding protein 1
chr1_+_207454230 0.24 ENST00000367058.7
ENST00000367059.3
ENST00000367057.8
complement C3d receptor 2
chr12_+_38316753 0.24 ENST00000551464.1
ENST00000308742.9
ALG10 alpha-1,2-glucosyltransferase B
chr10_-_102120318 0.24 ENST00000673968.1
LIM domain binding 1
chr1_-_165355746 0.23 ENST00000367893.4
LIM homeobox transcription factor 1 alpha
chr1_+_160190567 0.23 ENST00000368078.8
calsequestrin 1
chr11_-_57322197 0.23 ENST00000532437.1
tankyrase 1 binding protein 1
chr9_-_34397800 0.23 ENST00000297623.7
chromosome 9 open reading frame 24
chr1_+_18630839 0.23 ENST00000420770.7
paired box 7
chr8_+_97887903 0.23 ENST00000520016.5
matrilin 2
chr10_-_44385043 0.22 ENST00000374426.6
ENST00000395794.2
ENST00000374429.6
ENST00000395793.7
ENST00000343575.10
ENST00000395795.5
C-X-C motif chemokine ligand 12
chr21_-_15064934 0.22 ENST00000400199.5
ENST00000400202.5
ENST00000318948.7
nuclear receptor interacting protein 1
chr11_-_93741479 0.22 ENST00000448108.7
ENST00000532455.1
TATA-box binding protein associated factor, RNA polymerase I subunit D
chr20_-_49278416 0.22 ENST00000371754.8
zinc finger NFX1-type containing 1
chr4_-_74794514 0.22 ENST00000395743.8
betacellulin
chr19_+_1067493 0.22 ENST00000586866.5
Rho GTPase activating protein 45
chr11_+_8682782 0.22 ENST00000531978.5
ENST00000524496.5
ENST00000532359.5
ENST00000314138.11
ENST00000530022.5
ribosomal protein L27a
chr10_-_49762276 0.22 ENST00000374103.9
oxoglutarate dehydrogenase L
chr17_-_4545065 0.21 ENST00000572759.1
MYB binding protein 1a
chr6_-_31582415 0.21 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr12_+_103930600 0.21 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr10_-_49762335 0.21 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr1_-_24964984 0.21 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr9_-_125241327 0.21 ENST00000324460.7
ENST00000680272.1
ENST00000680032.1
heat shock protein family A (Hsp70) member 5
chr21_+_42219111 0.21 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr14_+_92513766 0.21 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chr6_+_83853576 0.21 ENST00000369687.2
ripply transcriptional repressor 2
chr1_+_32209074 0.20 ENST00000409358.2
doublecortin domain containing 2B
chr20_+_43916142 0.20 ENST00000423191.6
ENST00000372999.5
TOX high mobility group box family member 2
chr14_+_93927259 0.20 ENST00000556222.1
ENST00000554404.1
family with sequence similarity 181 member A
chr19_+_1067144 0.20 ENST00000313093.7
Rho GTPase activating protein 45
chr14_-_21269451 0.20 ENST00000336053.10
heterogeneous nuclear ribonucleoprotein C
chr18_+_58195390 0.20 ENST00000456173.6
ENST00000676226.1
ENST00000675865.1
NEDD4 like E3 ubiquitin protein ligase
chr2_+_218568865 0.20 ENST00000295701.9
CCR4-NOT transcription complex subunit 9
chr4_-_146521891 0.20 ENST00000394059.8
ENST00000502607.1
ENST00000335472.12
ENST00000432059.6
solute carrier family 10 member 7
chr2_+_159712457 0.20 ENST00000539065.5
ENST00000259050.8
ENST00000409175.6
ENST00000421037.1
membrane associated ring-CH-type finger 7
chr10_+_71964373 0.20 ENST00000373115.5
carbohydrate sulfotransferase 3
chr3_-_42773215 0.19 ENST00000310232.11
coiled-coil domain containing 13
chrX_-_31266925 0.19 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr1_+_169106681 0.19 ENST00000367815.9
ATPase Na+/K+ transporting subunit beta 1
chr1_-_156601435 0.19 ENST00000438976.6
ENST00000368232.9
ENST00000415314.6
G-patch domain containing 4
chr12_+_103930332 0.19 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
heat shock protein 90 beta family member 1
chr9_+_136952896 0.19 ENST00000371632.7
lipocalin 12
chr2_+_10122730 0.19 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr12_-_213338 0.19 ENST00000424061.6
solute carrier family 6 member 12
chr11_-_107858777 0.19 ENST00000525815.6
solute carrier family 35 member F2
chr1_+_200027605 0.18 ENST00000236914.7
nuclear receptor subfamily 5 group A member 2
chr11_+_57667974 0.18 ENST00000528177.5
ENST00000287169.8
zinc finger DHHC-type palmitoyltransferase 5
chr17_-_82840010 0.18 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr19_+_1067272 0.18 ENST00000590214.5
Rho GTPase activating protein 45
chr3_-_149333619 0.18 ENST00000296059.7
transmembrane 4 L six family member 18
chr2_+_219597838 0.18 ENST00000456909.6
serine/threonine kinase 11 interacting protein
chr20_-_13784880 0.18 ENST00000202816.5
ENST00000617257.2
ESF1 nucleolar pre-rRNA processing protein homolog
chr1_+_15847698 0.18 ENST00000375759.8
spen family transcriptional repressor
chr12_-_89524734 0.18 ENST00000529983.3
polypeptide N-acetylgalactosaminyltransferase 4
chr11_+_20599602 0.18 ENST00000525748.6
solute carrier family 6 member 5
chr6_+_44342684 0.18 ENST00000288390.2
spermatogenesis associated serine rich 1
chr3_-_108090971 0.17 ENST00000355354.13
ENST00000361309.6
CD47 molecule
chr7_+_77840122 0.17 ENST00000450574.5
ENST00000248550.7
putative homeodomain transcription factor 2
chr11_+_3797819 0.17 ENST00000396986.6
ENST00000300730.10
ENST00000396993.8
ENST00000532523.5
ENST00000459679.5
ENST00000464229.5
ENST00000464261.5
ENST00000490830.5
ENST00000464906.6
ENST00000464441.5
post-GPI attachment to proteins 2
chr19_-_18438150 0.17 ENST00000581800.5
ENST00000583534.1
ENST00000457269.8
inositol-3-phosphate synthase 1
chr9_+_129036614 0.17 ENST00000684074.1
mitoguardin 2
chr12_+_112791933 0.17 ENST00000551052.5
ENST00000415485.7
rabphilin 3A
chr6_-_43528867 0.17 ENST00000455285.2
exportin 5
chr6_+_110982028 0.17 ENST00000441448.7
ribosome production factor 2 homolog
chr3_-_129893551 0.17 ENST00000505616.5
ENST00000426664.6
ENST00000648771.1
ENST00000393238.8
transmembrane and coiled-coil domain family 1
chr10_+_5412542 0.17 ENST00000355029.9
neuroepithelial cell transforming 1
chr6_+_44342639 0.17 ENST00000674044.1
ENST00000515220.5
ENST00000323108.12
spermatogenesis associated serine rich 1
chr5_-_180802790 0.17 ENST00000504671.1
ENST00000507384.1
ENST00000307826.5
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr19_+_4402615 0.17 ENST00000301280.10
chromatin assembly factor 1 subunit A
chr6_+_24774925 0.17 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chr9_+_136665745 0.16 ENST00000371698.3
EGF like domain multiple 7
chr16_+_31393329 0.16 ENST00000389202.3
integrin subunit alpha D
chr10_-_119872832 0.16 ENST00000369077.4
minichromosome maintenance complex binding protein
chr1_+_236795254 0.16 ENST00000366577.10
ENST00000674797.2
5-methyltetrahydrofolate-homocysteine methyltransferase
chr8_-_67746348 0.16 ENST00000297770.10
carboxypeptidase A6
chr18_-_50287570 0.16 ENST00000586837.1
ENST00000412036.6
ENST00000589940.5
ENST00000587396.1
ENST00000591474.5
ENST00000285106.11
CXXC finger protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.4 1.4 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.3 1.0 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.2 3.2 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 0.7 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 0.6 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 0.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.3 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.4 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 0.4 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.8 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.3 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 0.5 GO:0035627 ceramide transport(GO:0035627)
0.1 0.6 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.4 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.1 0.5 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.6 GO:0034436 glycoprotein transport(GO:0034436)
0.1 1.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.2 GO:0002934 desmosome organization(GO:0002934)
0.1 0.5 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.7 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.3 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.9 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.9 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.1 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.1 0.6 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.2 GO:0070378 positive regulation of ERK5 cascade(GO:0070378)
0.1 0.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.1 0.3 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.2 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.1 0.2 GO:1903891 regulation of ATF6-mediated unfolded protein response(GO:1903891)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.0 1.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0048377 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 0.6 GO:0090178 regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.6 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) floor plate development(GO:0033504)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:1903237 positive regulation of dopamine secretion(GO:0033603) negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.2 GO:0036018 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:1903611 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.0 0.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 2.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) regulation of forebrain neuron differentiation(GO:2000977)
0.0 0.1 GO:0072526 quinolinate metabolic process(GO:0046874) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.2 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0072534 perineuronal net(GO:0072534)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 1.2 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.5 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.4 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.4 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 2.0 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.6 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 0.6 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.2 0.7 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.2 0.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.8 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0047750 cholestenol delta-isomerase activity(GO:0047750)
0.1 3.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.3 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 1.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.5 GO:0008009 chemokine activity(GO:0008009)
0.0 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)