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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TP53

Z-value: 1.40

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
ENSG00000141510.18 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg38_v1_chr17_-_7687427_76875380.294.9e-01Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51001138 1.48 ENST00000593490.1
kallikrein related peptidase 8
chr10_-_47484133 1.12 ENST00000583911.5
ENST00000611843.4
annexin A8
chr10_+_46375645 1.11 ENST00000622769.4
annexin A8 like 1
chr10_+_46375619 1.10 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr18_-_31042808 1.04 ENST00000434452.5
desmocollin 3
chr10_-_47484081 1.02 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
annexin A8
chr18_-_31042733 0.98 ENST00000360428.9
desmocollin 3
chr6_+_36130484 0.95 ENST00000373766.9
ENST00000211287.9
mitogen-activated protein kinase 13
chr15_+_40239857 0.93 ENST00000260404.8
p21 (RAC1) activated kinase 6
chr3_-_12759224 0.86 ENST00000314124.12
ENST00000435218.6
ENST00000435575.5
transmembrane protein 40
chr8_-_10730498 0.76 ENST00000304501.2
SRY-box transcription factor 7
chr11_-_108593738 0.64 ENST00000525344.5
ENST00000265843.9
exophilin 5
chr19_+_17795129 0.62 ENST00000600777.1
ENST00000318683.7
ENST00000595387.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr16_+_57620077 0.62 ENST00000567835.5
ENST00000569372.5
ENST00000563548.5
ENST00000562003.5
adhesion G protein-coupled receptor G1
chr16_+_57619942 0.62 ENST00000568908.5
ENST00000568909.5
ENST00000566778.5
ENST00000561988.5
adhesion G protein-coupled receptor G1
chr10_-_121596117 0.61 ENST00000351936.11
fibroblast growth factor receptor 2
chr11_+_1834804 0.57 ENST00000341958.3
synaptotagmin 8
chr9_-_133121148 0.56 ENST00000372047.7
ral guanine nucleotide dissociation stimulator
chr1_-_209652329 0.53 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chr9_-_133121228 0.49 ENST00000372050.8
ral guanine nucleotide dissociation stimulator
chr1_-_12618198 0.48 ENST00000616661.5
dehydrogenase/reductase 3
chr13_+_36432487 0.47 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr10_+_46375721 0.46 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
novel transcript
annexin A8 like 1
chr11_+_1834415 0.45 ENST00000381968.7
ENST00000381978.7
synaptotagmin 8
chr2_-_234497035 0.45 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr6_-_138107412 0.43 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr16_+_57372481 0.41 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr16_+_57372465 0.40 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr10_-_103452356 0.39 ENST00000260743.10
calcium homeostasis modulator family member 2
chr4_+_48986268 0.38 ENST00000226432.9
cell wall biogenesis 43 C-terminal homolog
chr19_+_3136026 0.37 ENST00000262958.4
G protein subunit alpha 15
chr1_+_13584262 0.36 ENST00000376061.8
ENST00000513143.5
podoplanin
chr8_-_23225061 0.36 ENST00000613472.1
ENST00000221132.8
TNF receptor superfamily member 10a
chr1_-_54406385 0.36 ENST00000610401.5
single stranded DNA binding protein 3
chr1_+_13583762 0.34 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr10_-_103452384 0.34 ENST00000369788.7
calcium homeostasis modulator family member 2
chr1_-_10472475 0.33 ENST00000377036.2
ENST00000377038.8
DNA fragmentation factor subunit alpha
chr8_-_23069012 0.31 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr4_-_48906788 0.31 ENST00000273860.8
OCIA domain containing 2
chr6_-_30744537 0.31 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr22_+_37906275 0.30 ENST00000215957.10
ENST00000445494.6
ENST00000680578.1
ENST00000424008.2
MICAL like 1
chr1_-_201469151 0.30 ENST00000367311.5
ENST00000367309.1
pleckstrin homology like domain family A member 3
chr4_-_48906720 0.29 ENST00000381464.6
ENST00000508632.6
OCIA domain containing 2
chr9_+_136952256 0.28 ENST00000371633.8
lipocalin 12
chr11_-_44950839 0.28 ENST00000395648.7
ENST00000531928.6
tumor protein p53 inducible protein 11
chr1_+_1033987 0.28 ENST00000651234.1
ENST00000652369.1
agrin
chr4_-_48906805 0.27 ENST00000620187.4
OCIA domain containing 2
chr9_+_136952896 0.27 ENST00000371632.7
lipocalin 12
chr11_+_706595 0.27 ENST00000531348.5
ENST00000530636.5
EPS8 like 2
chr2_-_25982471 0.26 ENST00000264712.8
kinesin family member 3C
chr16_+_527698 0.26 ENST00000219611.7
ENST00000562370.5
ENST00000568988.5
calpain 15
chr20_+_44355692 0.24 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr11_+_64291992 0.23 ENST00000394525.6
potassium two pore domain channel subfamily K member 4
chr22_+_46674593 0.23 ENST00000408031.1
GRAM domain containing 4
chr1_-_37947010 0.23 ENST00000458109.6
ENST00000373024.8
ENST00000373023.6
inositol polyphosphate-5-phosphatase B
chr2_+_232870284 0.22 ENST00000331342.4
secondary ossification center associated regulator of chondrocyte maturation
chr1_+_9997220 0.21 ENST00000294435.8
retinol binding protein 7
chr4_-_152536045 0.21 ENST00000603548.6
ENST00000281708.10
F-box and WD repeat domain containing 7
chr11_-_65540610 0.20 ENST00000532661.5
latent transforming growth factor beta binding protein 3
chr14_-_103522696 0.20 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr9_-_135961310 0.20 ENST00000371756.4
UBA domain containing 1
chr1_+_11736068 0.20 ENST00000376637.7
angiotensin II receptor associated protein
chr19_-_42242526 0.19 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr6_-_132714045 0.18 ENST00000367928.5
vanin 1
chr5_-_95961830 0.18 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr14_+_92513766 0.18 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chr19_+_56141317 0.18 ENST00000592949.5
zinc finger protein 444
chr19_+_56141277 0.17 ENST00000337080.8
ENST00000586123.5
zinc finger protein 444
chr6_+_36676455 0.17 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr6_+_24402908 0.17 ENST00000274747.11
ENST00000443868.6
ENST00000378386.8
ENST00000378353.5
magnesium transporter MRS2
chr8_+_42338454 0.17 ENST00000532157.5
ENST00000520008.5
DNA polymerase beta
chr8_+_42338477 0.16 ENST00000518925.5
ENST00000265421.9
DNA polymerase beta
chr1_+_11736120 0.16 ENST00000400895.6
ENST00000314340.10
ENST00000376629.8
ENST00000376627.6
ENST00000452018.6
ENST00000510878.1
angiotensin II receptor associated protein
chr19_-_47232649 0.16 ENST00000449228.5
ENST00000300880.11
ENST00000341983.8
BCL2 binding component 3
chr19_-_51027662 0.16 ENST00000594768.5
kallikrein related peptidase 11
chr1_-_156082412 0.15 ENST00000532414.3
mex-3 RNA binding family member A
chr1_+_25272492 0.15 ENST00000454452.6
Rh blood group D antigen
chr16_-_4614876 0.15 ENST00000591401.5
ENST00000283474.12
ENST00000591897.5
UBA like domain containing 1
chr1_-_156248084 0.15 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr6_+_36676489 0.15 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr1_-_156248038 0.15 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr1_-_156248013 0.14 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr11_+_64306227 0.13 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr2_+_168456215 0.13 ENST00000392687.4
ENST00000305747.11
ceramide synthase 6
chr1_+_107139996 0.13 ENST00000370073.6
ENST00000370074.8
netrin G1
chr1_+_3772722 0.13 ENST00000642557.4
ENST00000561886.2
ENST00000444870.7
small integral membrane protein 1 (Vel blood group)
chr1_+_25272439 0.13 ENST00000648012.1
Rh blood group D antigen
chrX_+_100644183 0.13 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr20_-_23637933 0.13 ENST00000398411.5
cystatin C
chr7_+_43583091 0.13 ENST00000319357.6
serine/threonine kinase 17a
chr1_-_248859067 0.13 ENST00000496231.1
ENST00000306601.9
ENST00000366471.7
zinc finger protein 692
chr11_+_119168705 0.12 ENST00000409109.6
ENST00000409991.5
ENST00000292199.6
NLR family member X1
chr22_+_19718390 0.12 ENST00000383045.7
ENST00000438754.6
septin 5
chr8_-_108787563 0.12 ENST00000297459.4
transmembrane protein 74
chr1_-_1421248 0.12 ENST00000442470.1
ENST00000537107.6
ankyrin repeat domain 65
chr5_-_73565602 0.11 ENST00000296785.8
ankyrin repeat family A member 2
chr1_+_43991588 0.11 ENST00000372318.8
coiled-coil domain containing 24
chr1_-_1421302 0.11 ENST00000520296.5
ankyrin repeat domain 65
chr11_-_47378494 0.11 ENST00000533030.1
Spi-1 proto-oncogene
chr10_-_125158704 0.11 ENST00000531469.5
C-terminal binding protein 2
chr7_+_48088596 0.10 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr20_-_1393045 0.10 ENST00000400137.9
ENST00000381715.4
FKBP prolyl isomerase 1A
chr19_-_6481769 0.10 ENST00000381480.7
ENST00000543576.5
ENST00000590173.5
DENN domain containing 1C
chr12_-_64390691 0.10 ENST00000333722.9
chromosome 12 open reading frame 56
chr22_-_17774482 0.10 ENST00000399765.5
ENST00000614949.4
ENST00000399767.6
BH3 interacting domain death agonist
chr17_+_27456393 0.10 ENST00000644974.1
kinase suppressor of ras 1
chr9_-_113275560 0.09 ENST00000374206.4
cell division cycle 26
chr22_-_17774412 0.09 ENST00000342111.9
ENST00000622694.5
BH3 interacting domain death agonist
chr19_-_42217667 0.09 ENST00000336034.8
ENST00000596251.6
ENST00000598200.1
ENST00000598727.5
death effector domain containing 2
chr17_+_18225672 0.09 ENST00000621229.1
LLGL scribble cell polarity complex component 1
chr11_+_119168188 0.09 ENST00000454811.5
ENST00000409265.8
ENST00000449394.5
NLR family member X1
chr7_-_72969466 0.09 ENST00000285805.3
tripartite motif containing 74
chr4_-_158723355 0.09 ENST00000307720.4
peptidylprolyl isomerase D
chr3_+_44338452 0.09 ENST00000396078.7
T cell activation inhibitor, mitochondrial
chr7_+_75395629 0.09 ENST00000323819.7
ENST00000430211.5
tripartite motif containing 73
chr19_-_1605425 0.09 ENST00000589880.1
ENST00000591899.8
ENST00000585671.2
ubiquinol-cytochrome c reductase, complex III subunit XI
chr12_+_108562579 0.09 ENST00000311893.14
ENST00000535729.5
ENST00000431221.6
ENST00000547005.5
ENST00000392807.8
ENST00000539593.1
iron-sulfur cluster assembly enzyme
chr11_+_65181687 0.09 ENST00000527739.5
ENST00000526966.5
ENST00000533129.5
ENST00000524773.5
calpain 1
chr17_+_76376581 0.09 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr1_-_1246722 0.09 ENST00000330388.2
C1q and TNF related 12
chr15_-_65185299 0.09 ENST00000300107.7
caseinolytic mitochondrial matrix peptidase chaperone subunit X
chr2_+_95025700 0.09 ENST00000309988.9
ENST00000353004.7
ENST00000354078.7
ENST00000349807.3
mal, T cell differentiation protein
chr11_-_75306688 0.09 ENST00000532525.1
arrestin beta 1
chr11_-_129192291 0.08 ENST00000682385.1
Rho GTPase activating protein 32
chr1_-_25420792 0.08 ENST00000346452.8
ENST00000340849.8
ENST00000349438.8
ENST00000413854.5
ENST00000294413.13
Rh blood group CcEe antigens
chr8_-_123241336 0.08 ENST00000276704.6
chromosome 8 open reading frame 76
chr19_+_44671722 0.08 ENST00000403660.3
CEA cell adhesion molecule 19
chr19_+_50790415 0.08 ENST00000270593.2
acid phosphatase 4
chr2_-_74529670 0.08 ENST00000377526.4
AUP1 lipid droplet regulating VLDL assembly factor
chr12_+_12813316 0.08 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DEAD-box helicase 47
chr18_+_9913979 0.08 ENST00000400000.7
ENST00000340541.4
VAMP associated protein A
chr11_-_129192198 0.08 ENST00000310343.13
Rho GTPase activating protein 32
chr12_+_123602085 0.08 ENST00000238146.9
ENST00000538744.5
DEAD-box helicase 55
chr7_+_157139195 0.08 ENST00000389103.4
ubiquitin protein ligase E3C
chr17_-_63446260 0.08 ENST00000448884.6
ENST00000582297.5
ENST00000360793.8
ENST00000582034.5
ENST00000578072.1
cytochrome b561
chr6_-_100881281 0.08 ENST00000369143.2
ENST00000369162.7
ENST00000324723.10
ENST00000522650.5
activating signal cointegrator 1 complex subunit 3
chr19_+_44671452 0.08 ENST00000358777.9
CEA cell adhesion molecule 19
chr4_+_41935423 0.08 ENST00000504986.6
transmembrane protein 33
chr8_-_12194067 0.08 ENST00000524571.6
ENST00000533852.6
ENST00000533513.1
ENST00000448228.6
ENST00000534520.5
family with sequence similarity 86 member B1
chr12_+_53500885 0.08 ENST00000456234.6
TARBP2 subunit of RISC loading complex
chr18_-_36829154 0.08 ENST00000614939.4
ENST00000610723.4
tubulin polyglutamylase complex subunit 2
chr11_+_33257265 0.07 ENST00000303296.9
ENST00000379016.7
homeodomain interacting protein kinase 3
chr17_-_14236862 0.07 ENST00000420162.7
ENST00000431716.2
CMT1A duplicated region transcript 15
chr22_+_40370578 0.07 ENST00000457767.5
ENST00000248929.14
small G protein signaling modulator 3
chr12_+_53501578 0.07 ENST00000552817.5
ENST00000394357.6
TARBP2 subunit of RISC loading complex
chr5_+_122312229 0.07 ENST00000261368.13
synuclein alpha interacting protein
chr7_-_100168602 0.07 ENST00000423751.2
ENST00000360039.9
galactose-3-O-sulfotransferase 4
chr22_+_28772664 0.07 ENST00000448492.6
ENST00000421503.6
ENST00000249064.9
ENST00000444523.1
coiled-coil domain containing 117
chr18_+_59899988 0.07 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr5_-_113488415 0.07 ENST00000408903.7
MCC regulator of WNT signaling pathway
chr17_+_18183803 0.07 ENST00000399138.5
alkB homolog 5, RNA demethylase
chr12_+_53501272 0.07 ENST00000552857.5
ENST00000266987.7
ENST00000547064.5
TARBP2 subunit of RISC loading complex
chr20_+_4148779 0.07 ENST00000621355.4
ENST00000339123.10
ENST00000278795.7
ENST00000305958.9
ENST00000346595.6
spermine oxidase
chr5_+_122312164 0.07 ENST00000514497.6
ENST00000261367.11
synuclein alpha interacting protein
chr20_-_1393074 0.07 ENST00000614856.2
ENST00000678408.1
ENST00000618612.5
ENST00000439640.5
ENST00000381719.8
ENST00000677533.1
FKBP prolyl isomerase 1A
chr20_-_62427528 0.07 ENST00000252998.2
RBBP8 N-terminal like
chr20_+_58692767 0.07 ENST00000356091.11
aminopeptidase like 1
chr11_-_77411883 0.07 ENST00000528203.5
ENST00000528592.5
ENST00000528633.1
ENST00000529248.5
p21 (RAC1) activated kinase 1
chr11_-_69819410 0.06 ENST00000334134.4
fibroblast growth factor 3
chr2_-_241508630 0.06 ENST00000403346.7
ENST00000535007.5
serine/threonine kinase 25
chr1_-_150765735 0.06 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr11_-_3057386 0.06 ENST00000529772.5
ENST00000278224.13
ENST00000380525.9
cysteinyl-tRNA synthetase 1
chr19_+_35371290 0.06 ENST00000597214.1
G protein-coupled receptor 42
chr12_+_56104527 0.06 ENST00000552766.5
ENST00000303305.11
proliferation-associated 2G4
chr19_-_51646800 0.06 ENST00000599649.5
ENST00000429354.3
ENST00000360844.6
sialic acid binding Ig like lectin 5
sialic acid binding Ig like lectin 14
chr1_+_54053573 0.06 ENST00000234827.6
transcription elongation factor A N-terminal and central domain containing 2
chr12_+_101666203 0.06 ENST00000549608.1
myosin binding protein C1
chr1_+_243256034 0.06 ENST00000366541.8
SHH signaling and ciliogenesis regulator SDCCAG8
chr12_+_12070932 0.06 ENST00000308721.9
BCL2 like 14
chr3_-_39281663 0.06 ENST00000358309.3
C-X3-C motif chemokine receptor 1
chr7_+_157138912 0.06 ENST00000611269.4
ENST00000348165.10
ubiquitin protein ligase E3C
chr18_-_36828771 0.06 ENST00000589049.5
ENST00000587129.5
ENST00000590842.5
tubulin polyglutamylase complex subunit 2
chr9_-_101398590 0.06 ENST00000374865.5
mitochondrial ribosomal protein L50
chr20_-_23826721 0.06 ENST00000304725.3
cystatin SA
chr1_+_26159071 0.05 ENST00000374268.5
family with sequence similarity 110 member D
chr19_+_13877123 0.05 ENST00000339133.6
ENST00000397555.3
nanos C2HC-type zinc finger 3
chr9_-_127122623 0.05 ENST00000373417.1
ENST00000373425.8
angiopoietin like 2
chr19_-_54364983 0.05 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr7_-_45088888 0.05 ENST00000490531.3
NAC alpha domain containing
chr16_-_58198059 0.05 ENST00000262506.8
casein kinase 2 alpha 2
chr1_-_150765785 0.05 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr5_-_176610104 0.05 ENST00000303991.5
G protein regulated inducer of neurite outgrowth 1
chr7_-_44490609 0.05 ENST00000355451.8
NudC domain containing 3
chr19_+_43576800 0.05 ENST00000612042.4
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr5_+_10564064 0.05 ENST00000296657.7
ankyrin repeat domain 33B
chr9_+_114611206 0.05 ENST00000374049.4
ENST00000288502.9
transmembrane protein 268
chr10_-_71851313 0.05 ENST00000394934.4
ENST00000610929.3
prosaposin
chr12_+_51591216 0.05 ENST00000668547.1
ENST00000354534.11
ENST00000627620.5
ENST00000545061.5
sodium voltage-gated channel alpha subunit 8
chr19_-_55179390 0.05 ENST00000590851.5
synaptotagmin 5
chr11_+_45805108 0.05 ENST00000530471.1
ENST00000314134.4
solute carrier family 35 member C1
chr17_+_18225582 0.05 ENST00000316843.9
LLGL scribble cell polarity complex component 1
chr19_+_19385815 0.04 ENST00000494516.6
ENST00000360315.7
GATA zinc finger domain containing 2A
chr11_+_64359142 0.04 ENST00000528057.5
ENST00000334205.9
ribosomal protein S6 kinase A4
chr2_-_241508547 0.04 ENST00000405883.7
serine/threonine kinase 25
chr5_+_218241 0.04 ENST00000617470.4
ENST00000504309.5
ENST00000510361.5
ENST00000264932.11
succinate dehydrogenase complex flavoprotein subunit A
chr1_+_26826682 0.04 ENST00000374142.9
zinc finger DHHC-type palmitoyltransferase 18
chr14_-_36521149 0.04 ENST00000518149.5
NK2 homeobox 1
chr1_+_42846573 0.04 ENST00000372502.5
ENST00000372508.7
ENST00000651192.1
ENST00000372507.5
ENST00000372506.5
ENST00000372504.5
zinc finger protein 691
chr3_-_52445085 0.04 ENST00000475739.1
ENST00000231721.7
semaphorin 3G
chr3_-_45995807 0.04 ENST00000535325.5
ENST00000296137.7
FYVE and coiled-coil domain autophagy adaptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.3 0.8 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.2 0.7 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.6 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.6 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 1.5 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.3 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 1.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.3 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.3 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.4 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.4 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.4 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 2.1 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.0 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.0 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) Golgi reassembly(GO:0090168)
0.0 0.8 GO:0001706 endoderm formation(GO:0001706)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.5 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 2.4 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 0.5 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 2.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 3.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.0 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 4.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway