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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for UBP1

Z-value: 0.96

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Transcription factors associated with UBP1

Gene Symbol Gene ID Gene Info
ENSG00000153560.12 upstream binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
UBP1hg38_v1_chr3_-_33440343_33440413-0.502.1e-01Click!

Activity profile of UBP1 motif

Sorted Z-values of UBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_151141631 0.95 ENST00000523714.5
ENST00000521749.5
annexin A6
chr14_-_91946989 0.94 ENST00000556154.5
fibulin 5
chr14_-_91947383 0.85 ENST00000267620.14
fibulin 5
chr5_-_111757549 0.65 ENST00000419114.6
neuronal regeneration related protein
chr5_-_111758061 0.65 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chr5_-_111757643 0.61 ENST00000508870.5
neuronal regeneration related protein
chr5_-_111757704 0.55 ENST00000379671.7
neuronal regeneration related protein
chr1_-_168729187 0.50 ENST00000367817.4
dermatopontin
chr16_+_29812150 0.33 ENST00000647876.1
ENST00000567551.2
ENST00000567659.3
ENST00000637565.1
ENST00000358758.12
ENST00000636619.1
proline rich transmembrane protein 2
chr2_-_178478541 0.33 ENST00000424785.7
FKBP prolyl isomerase 7
chr16_+_29812230 0.33 ENST00000300797.7
ENST00000637403.1
ENST00000572820.2
ENST00000637064.1
ENST00000636246.1
proline rich transmembrane protein 2
chr8_+_76681208 0.24 ENST00000651372.2
zinc finger homeobox 4
chr3_+_29281552 0.24 ENST00000452462.5
ENST00000456853.1
RNA binding motif single stranded interacting protein 3
chr22_+_22375984 0.24 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr12_+_99647749 0.24 ENST00000324341.2
family with sequence similarity 71 member C
chr9_-_35685462 0.23 ENST00000607559.1
tropomyosin 2
chrX_+_54920796 0.21 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr10_+_80132591 0.19 ENST00000372267.6
placenta associated 9
chr10_+_21524627 0.18 ENST00000651097.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr5_-_94111627 0.17 ENST00000505869.5
ENST00000395965.8
ENST00000509163.5
family with sequence similarity 172 member A
chr4_-_119300546 0.17 ENST00000504110.2
chromosome 4 open reading frame 3
chr3_-_56468346 0.16 ENST00000288221.11
ELKS/RAB6-interacting/CAST family member 2
chrX_+_71254781 0.14 ENST00000677446.1
non-POU domain containing octamer binding
chr9_-_21482313 0.14 ENST00000448696.4
interferon epsilon
chr1_+_45012691 0.14 ENST00000469548.5
uroporphyrinogen decarboxylase
chr16_-_89719369 0.13 ENST00000561976.5
VPS9 domain containing 1
chr9_-_127873462 0.13 ENST00000223836.10
adenylate kinase 1
chr1_-_182672232 0.13 ENST00000508450.5
regulator of G protein signaling 8
chr1_-_182400660 0.12 ENST00000367565.2
transmembrane epididymal protein 1
chr7_+_142800957 0.12 ENST00000466254.1
T cell receptor beta constant 2
chrX_-_66033664 0.12 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr21_+_42403874 0.12 ENST00000319294.11
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr2_+_227813834 0.12 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr12_+_8914525 0.11 ENST00000543824.5
polyhomeotic homolog 1
chr7_+_143132069 0.11 ENST00000291009.4
prolactin induced protein
chr5_+_150671588 0.11 ENST00000523553.1
myozenin 3
chr12_-_123233097 0.11 ENST00000541437.5
ENST00000606320.6
M-phase phosphoprotein 9
chr22_-_36817510 0.10 ENST00000443735.1
parvalbumin
chrX_-_71255060 0.10 ENST00000373988.5
ENST00000373998.5
zinc finger MYM-type containing 3
chr2_+_169694434 0.10 ENST00000616481.4
ENST00000616524.4
ENST00000617738.4
ENST00000359744.8
ENST00000438838.5
ENST00000438710.5
ENST00000449906.5
ENST00000498202.6
ENST00000272797.8
phosphatase, orphan 2
kelch like family member 23
chr11_+_7485492 0.10 ENST00000534244.1
ENST00000329293.4
olfactomedin like 1
chr5_-_59430600 0.10 ENST00000636120.1
phosphodiesterase 4D
chr17_-_5234801 0.10 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr19_+_49361783 0.10 ENST00000594268.1
dickkopf like acrosomal protein 1
chr17_-_3292600 0.10 ENST00000615105.1
olfactory receptor family 3 subfamily A member 1
chr16_+_31108294 0.10 ENST00000287507.7
ENST00000394950.7
ENST00000219794.11
ENST00000561755.1
branched chain keto acid dehydrogenase kinase
chr5_+_123512087 0.09 ENST00000345990.8
casein kinase 1 gamma 3
chrX_-_19970298 0.09 ENST00000379687.7
ENST00000379682.8
BCLAF1 and THRAP3 family member 3
chr1_+_148889403 0.09 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
phosphodiesterase 4D interacting protein
chr1_+_53014926 0.09 ENST00000430330.6
ENST00000408941.7
ENST00000478274.6
ENST00000484100.5
ENST00000435345.6
ENST00000488965.1
sterol carrier protein 2
chr10_-_49134021 0.09 ENST00000311787.6
family with sequence similarity 170 member B
chr3_+_37990768 0.09 ENST00000383759.7
villin like
chr2_+_161231078 0.08 ENST00000439442.1
TRAF family member associated NFKB activator
chr21_+_44646414 0.07 ENST00000334670.9
keratin associated protein 10-11
chr22_+_22811737 0.07 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr11_-_60855943 0.07 ENST00000332539.5
prostaglandin D2 receptor 2
chr4_-_82430192 0.07 ENST00000621267.4
ENST00000614627.4
heterogeneous nuclear ribonucleoprotein D like
chr5_-_131994225 0.06 ENST00000543479.5
ENST00000431707.5
acyl-CoA synthetase long chain family member 6
chr1_-_182672882 0.06 ENST00000367557.8
ENST00000258302.8
regulator of G protein signaling 8
chr13_-_23375431 0.06 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
sacsin molecular chaperone
chr1_+_17580474 0.06 ENST00000375415.5
Rho guanine nucleotide exchange factor 10 like
chr1_+_48222685 0.06 ENST00000533824.5
ENST00000236495.9
ENST00000438567.7
solute carrier family 5 member 9
chr1_-_152360004 0.05 ENST00000388718.5
filaggrin family member 2
chr12_+_123233420 0.05 ENST00000253233.6
ENST00000366329.7
ENST00000546132.2
ENST00000536130.2
chromosome 12 open reading frame 65
chr16_+_28846674 0.05 ENST00000322610.12
SH2B adaptor protein 1
chr1_-_150697128 0.05 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chrX_+_75274060 0.05 ENST00000373383.9
ENST00000373379.5
uracil phosphoribosyltransferase homolog
chr6_+_31587185 0.04 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
leukocyte specific transcript 1
chr2_-_2331336 0.04 ENST00000648933.1
ENST00000644820.1
myelin transcription factor 1 like
chr2_-_2331225 0.04 ENST00000648627.1
ENST00000649663.1
ENST00000650560.1
ENST00000428368.7
ENST00000648316.1
ENST00000648665.1
ENST00000649313.1
ENST00000399161.7
ENST00000647738.2
myelin transcription factor 1 like
chr17_-_50373173 0.04 ENST00000225969.9
ENST00000503633.5
ENST00000442592.3
mitochondrial ribosomal protein L27
chr6_+_31587268 0.04 ENST00000396101.7
ENST00000490742.5
leukocyte specific transcript 1
chr19_-_54100792 0.03 ENST00000391761.5
ENST00000356532.7
ENST00000616447.4
ENST00000359649.8
ENST00000358375.8
ENST00000391760.1
ENST00000351806.8
osteoclast associated Ig-like receptor
chr1_-_155244684 0.03 ENST00000428024.3
glucosylceramidase beta
chr14_+_75522427 0.03 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chrX_-_41923547 0.03 ENST00000378163.7
calcium/calmodulin dependent serine protein kinase
chr1_+_40709316 0.03 ENST00000372652.5
nuclear transcription factor Y subunit gamma
chr2_-_227379297 0.03 ENST00000304568.4
transmembrane 4 L six family member 20
chr9_-_6015607 0.03 ENST00000485372.1
ENST00000259569.6
ENST00000623170.1
RAN binding protein 6
chr6_+_6588082 0.03 ENST00000379953.6
lymphocyte antigen 86
chr7_+_133253064 0.03 ENST00000393161.6
ENST00000253861.5
exocyst complex component 4
chr2_-_89143133 0.02 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr1_-_150236150 0.02 ENST00000629042.2
acidic nuclear phosphoprotein 32 family member E
chr12_-_14938508 0.02 ENST00000266397.7
endoplasmic reticulum protein 27
chr12_-_122422662 0.02 ENST00000620786.5
CAP-Gly domain containing linker protein 1
chr11_-_31803620 0.02 ENST00000639006.1
paired box 6
chr1_-_150236064 0.02 ENST00000532744.2
ENST00000369114.9
ENST00000369115.3
ENST00000583931.6
acidic nuclear phosphoprotein 32 family member E
chr11_-_31803663 0.01 ENST00000638802.1
ENST00000638878.1
paired box 6
chr1_-_150235972 0.01 ENST00000534220.1
acidic nuclear phosphoprotein 32 family member E
chr19_-_51372269 0.01 ENST00000593572.5
ENST00000595157.1
natural killer cell granule protein 7
chr5_+_80035341 0.01 ENST00000350881.6
thrombospondin 4
chr4_+_155666963 0.01 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr3_+_111542134 0.00 ENST00000438817.6
CD96 molecule
chr17_+_42853232 0.00 ENST00000617500.4
amine oxidase copper containing 3
chr3_-_48563774 0.00 ENST00000273610.4
urocortin 2
chr1_-_150235943 0.00 ENST00000533654.5
acidic nuclear phosphoprotein 32 family member E
chr1_+_155135807 0.00 ENST00000368401.6
ENST00000622581.4
solute carrier family 50 member 1
chr1_-_150235995 0.00 ENST00000436748.6
acidic nuclear phosphoprotein 32 family member E

Network of associatons between targets according to the STRING database.

First level regulatory network of UBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.7 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.0 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)