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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for XBP1

Z-value: 1.88

Motif logo

Transcription factors associated with XBP1

Gene Symbol Gene ID Gene Info
ENSG00000100219.16 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
XBP1hg38_v1_chr22_-_28800042_28800133,
hg38_v1_chr22_-_28800558_28800597
-0.108.2e-01Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_94394886 5.05 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr5_-_9546066 2.44 ENST00000382496.10
ENST00000652226.1
semaphorin 5A
chr19_+_49527988 2.03 ENST00000270645.8
reticulocalbin 3
chr5_+_120464236 1.71 ENST00000407149.7
ENST00000379551.2
proline rich 16
chr5_-_122078249 1.32 ENST00000231004.5
lysyl oxidase
chr22_+_38468036 1.17 ENST00000409006.3
ENST00000216014.9
KDEL endoplasmic reticulum protein retention receptor 3
chr8_+_103372388 0.89 ENST00000520337.1
collagen triple helix repeat containing 1
chr14_+_99793375 0.84 ENST00000262233.11
ENST00000556714.5
EMAP like 1
chr10_+_87659839 0.80 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chrX_+_9463272 0.74 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr14_+_99793329 0.72 ENST00000334192.8
EMAP like 1
chr5_+_127517611 0.56 ENST00000296666.13
ENST00000442138.6
ENST00000512635.2
proline rich coiled-coil 1
chr5_-_10761156 0.56 ENST00000432074.2
ENST00000230895.11
death associated protein
chr3_+_105367212 0.56 ENST00000472644.6
activated leukocyte cell adhesion molecule
chr20_+_45416551 0.54 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chr20_+_45416084 0.52 ENST00000279035.14
ENST00000543458.7
ENST00000372689.9
ENST00000639499.1
ENST00000279036.12
ENST00000638594.1
ENST00000638489.1
ENST00000638353.1
ENST00000639382.1
ENST00000640210.1
ENST00000639235.1
ENST00000638478.1
ENST00000432270.2
ENST00000545755.3
ENST00000640324.1
phosphatidylinositol glycan anchor biosynthesis class T
chr20_-_17682060 0.48 ENST00000455029.3
ribosome binding protein 1
chr22_-_31107517 0.48 ENST00000400299.6
ENST00000611680.1
selenoprotein M
chr6_+_83193331 0.47 ENST00000369724.5
RWD domain containing 2A
chr12_-_98644733 0.43 ENST00000299157.5
ENST00000393042.3
IKBKB interacting protein
chr12_+_6944009 0.42 ENST00000229281.6
chromosome 12 open reading frame 57
chr12_+_6943811 0.42 ENST00000544681.1
ENST00000537087.5
chromosome 12 open reading frame 57
chr20_+_58891981 0.40 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS complex locus
chr6_+_131808011 0.40 ENST00000647893.1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr17_+_75110021 0.39 ENST00000584947.1
armadillo repeat containing 7
chr3_-_128052166 0.37 ENST00000648300.1
monoglyceride lipase
chr12_+_6944065 0.37 ENST00000540506.2
chromosome 12 open reading frame 57
chr17_+_66302606 0.36 ENST00000413366.8
protein kinase C alpha
chr6_-_83193207 0.36 ENST00000652468.1
ENST00000512866.5
ENST00000616566.5
ENST00000510258.1
ENST00000650642.1
ENST00000513973.6
ENST00000503094.1
ENST00000283977.9
ENST00000509219.2
ENST00000651425.1
ENST00000508748.5
phosphoglucomutase 3
chr5_+_154858594 0.36 ENST00000519430.5
ENST00000520671.5
ENST00000521583.5
ENST00000285896.11
ENST00000518028.5
ENST00000519404.5
ENST00000519394.5
ENST00000518775.5
CCR4-NOT transcription complex subunit 8
chr19_-_57947675 0.36 ENST00000598928.1
ENST00000282308.4
zinc finger protein 256
chr15_-_55588337 0.35 ENST00000563719.4
pygopus family PHD finger 1
chr10_-_126388455 0.35 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM metallopeptidase domain 12
chr7_-_27143672 0.34 ENST00000222726.4
homeobox A5
chr9_-_35689913 0.34 ENST00000329305.6
ENST00000645482.3
ENST00000647435.1
ENST00000378292.9
tropomyosin 2
chr9_+_35732649 0.33 ENST00000353704.3
cAMP responsive element binding protein 3
chr12_+_98645218 0.32 ENST00000551964.6
ENST00000333991.5
ENST00000357310.5
ENST00000359972.6
apoptotic peptidase activating factor 1
chr15_-_60397964 0.32 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
annexin A2
chr4_-_118836067 0.31 ENST00000280551.11
SEC24 homolog D, COPII coat complex component
chr3_-_183825513 0.31 ENST00000318631.8
ENST00000431348.1
MAP6 domain containing 1
chr20_+_25248036 0.30 ENST00000216962.9
glycogen phosphorylase B
chr12_-_55729660 0.30 ENST00000546457.1
ENST00000549117.5
CD63 molecule
chr3_-_105868964 0.29 ENST00000394030.8
Cbl proto-oncogene B
chr20_-_17682234 0.29 ENST00000377813.6
ENST00000377807.6
ENST00000360807.8
ENST00000398782.2
ribosome binding protein 1
chr6_+_33200860 0.29 ENST00000374677.8
solute carrier family 39 member 7
chr12_+_106955719 0.28 ENST00000548125.5
transmembrane protein 263
chr6_+_33200820 0.27 ENST00000374675.7
solute carrier family 39 member 7
chr5_-_177303675 0.27 ENST00000393611.6
ENST00000303270.6
ENST00000303251.11
RAB24, member RAS oncogene family
chr20_-_35092783 0.27 ENST00000451813.6
ENST00000252015.3
transient receptor potential cation channel subfamily C member 4 associated protein
chr5_-_94111627 0.26 ENST00000505869.5
ENST00000395965.8
ENST00000509163.5
family with sequence similarity 172 member A
chr2_+_241315092 0.26 ENST00000391973.6
septin 2
chr11_+_61828280 0.26 ENST00000521849.5
ENST00000278840.9
fatty acid desaturase 2
chr1_+_161153968 0.26 ENST00000368003.6
ubiquitin-fold modifier conjugating enzyme 1
chr17_-_44199206 0.26 ENST00000589805.1
ataxin 7 like 3
chr13_+_34942263 0.25 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr19_-_52095704 0.25 ENST00000594440.6
ENST00000426391.6
zinc finger protein 841
chr5_+_112861188 0.25 ENST00000503445.5
ENST00000505459.6
ENST00000282999.7
ENST00000391338.3
ENST00000515463.1
ENST00000621420.5
ENST00000445150.3
signal recognition particle 19
chr5_-_109409938 0.24 ENST00000361189.7
praja ring finger ubiquitin ligase 2
chr3_+_172040554 0.23 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr9_+_124015397 0.23 ENST00000488674.2
LIM homeobox 2
chr5_+_154858482 0.23 ENST00000519211.5
ENST00000522458.5
ENST00000519903.5
ENST00000521450.5
ENST00000403027.6
CCR4-NOT transcription complex subunit 8
chr20_+_33007695 0.23 ENST00000170150.4
BPI fold containing family B member 2
chr8_-_38269157 0.23 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
phospholipid phosphatase 5
chr3_-_139389604 0.23 ENST00000515006.5
ENST00000510181.6
ENST00000333188.10
ENST00000513274.5
ENST00000514508.2
ENST00000503326.6
ENST00000507777.6
ENST00000512242.6
ENST00000512153.5
ENST00000512309.2
COPI coat complex subunit beta 2
chr18_+_35241027 0.22 ENST00000330501.12
ENST00000601719.1
ENST00000591206.5
ENST00000261333.10
ENST00000355632.8
ENST00000585800.1
zinc finger protein 397
chr22_-_42857194 0.22 ENST00000437119.6
ENST00000454099.5
ENST00000263245.10
ADP ribosylation factor GTPase activating protein 3
chr11_+_17276708 0.21 ENST00000531172.5
ENST00000529010.6
ENST00000533738.6
ENST00000323688.10
nucleobindin 2
chr16_-_30534819 0.21 ENST00000395094.3
zinc finger protein 747
chr17_-_42423246 0.21 ENST00000357037.6
caveolae associated protein 1
chr8_-_38269116 0.21 ENST00000529359.5
phospholipid phosphatase 5
chr5_+_154858218 0.20 ENST00000523698.5
ENST00000517876.5
ENST00000520472.5
CCR4-NOT transcription complex subunit 8
chr10_-_22003678 0.20 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr15_-_60398733 0.20 ENST00000559818.6
annexin A2
chr2_+_241315223 0.20 ENST00000428282.5
ENST00000360051.7
septin 2
chr4_-_75724362 0.18 ENST00000677583.1
G3BP stress granule assembly factor 2
chr1_+_109090726 0.18 ENST00000338272.9
ENST00000651489.1
transmembrane protein 167B
chr3_-_28348805 0.18 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr1_-_21783134 0.18 ENST00000308271.14
ubiquitin specific peptidase 48
chr2_-_33599269 0.18 ENST00000431950.1
ENST00000403368.1
ENST00000238823.13
family with sequence similarity 98 member A
chr21_+_43719095 0.18 ENST00000468090.5
ENST00000291565.9
pyridoxal kinase
chr9_-_34522968 0.17 ENST00000399775.3
energy homeostasis associated
chr11_-_102705737 0.17 ENST00000260229.5
matrix metallopeptidase 27
chr14_+_69484722 0.17 ENST00000322564.9
pleckstrin homology and coiled-coil domain containing D1
chr19_+_54966343 0.17 ENST00000537859.5
ENST00000585500.5
ENST00000427260.6
ENST00000448584.7
ENST00000263437.10
NLR family pyrin domain containing 2
chr1_+_148952120 0.17 ENST00000313431.13
phosphodiesterase 4D interacting protein
chr9_-_35732122 0.17 ENST00000314888.10
talin 1
chr20_-_8019744 0.17 ENST00000246024.7
thioredoxin related transmembrane protein 4
chr4_-_75724386 0.16 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP stress granule assembly factor 2
chr2_-_69387188 0.16 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr15_-_55498317 0.16 ENST00000568310.1
ENST00000565113.5
ENST00000448430.6
ENST00000457155.6
DNAAF4-CCPG1 readthrough (NMD candidate)
dynein axonemal assembly factor 4
chr16_-_75536071 0.16 ENST00000336257.8
carbohydrate sulfotransferase 5
chr7_-_64982021 0.16 ENST00000610793.1
ENST00000620222.4
zinc finger protein 117
chr5_-_172454487 0.16 ENST00000311601.6
SH3 and PX domains 2B
chr4_+_75724569 0.16 ENST00000514213.7
ENST00000264904.8
USO1 vesicle transport factor
chr14_-_92040027 0.16 ENST00000267622.8
thyroid hormone receptor interactor 11
chr19_+_36115439 0.16 ENST00000629269.2
ENST00000221855.8
ENST00000651435.1
ENST00000589996.5
ENST00000591296.1
tubulin folding cofactor B
chr1_+_6785518 0.15 ENST00000467404.6
calmodulin binding transcription activator 1
chr12_+_56230652 0.15 ENST00000266980.8
ENST00000437277.1
solute carrier family 39 member 5
chr2_-_15561305 0.15 ENST00000281513.10
NBAS subunit of NRZ tethering complex
chr17_+_75109939 0.15 ENST00000581078.1
ENST00000245543.6
ENST00000582136.5
armadillo repeat containing 7
chr2_-_69387241 0.15 ENST00000361060.5
glutamine--fructose-6-phosphate transaminase 1
chr14_+_49620750 0.15 ENST00000305386.4
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr1_+_6785437 0.15 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
calmodulin binding transcription activator 1
chr2_-_241315180 0.15 ENST00000441124.5
ENST00000391976.6
high density lipoprotein binding protein
chr4_+_127730386 0.14 ENST00000281154.6
solute carrier family 25 member 31
chr3_+_33114007 0.14 ENST00000320954.11
cartilage associated protein
chr2_+_84905644 0.14 ENST00000233143.6
thymosin beta 10
chr1_-_21783189 0.13 ENST00000400301.5
ENST00000532737.1
ubiquitin specific peptidase 48
chr1_+_21509415 0.13 ENST00000374840.8
ENST00000539907.5
ENST00000540617.5
alkaline phosphatase, biomineralization associated
chr20_+_45791978 0.13 ENST00000449078.5
ENST00000456939.5
deoxynucleotidyltransferase terminal interacting protein 1
chr14_-_24195570 0.13 ENST00000530468.5
ENST00000528010.1
ENST00000396854.8
ENST00000524835.5
ENST00000525592.1
transmembrane 9 superfamily member 1
chr14_+_39267055 0.13 ENST00000396158.6
ENST00000280083.7
ENST00000341502.9
MIA SH3 domain ER export factor 2
chr17_+_38870050 0.13 ENST00000318008.11
ENST00000435347.7
LIM and SH3 protein 1
chr1_+_148952341 0.12 ENST00000529945.2
phosphodiesterase 4D interacting protein
chr20_+_45791930 0.12 ENST00000372622.8
deoxynucleotidyltransferase terminal interacting protein 1
chr1_+_26432299 0.12 ENST00000427245.6
ENST00000236342.12
ENST00000525682.6
ENST00000526219.5
ENST00000374185.7
ENST00000360009.6
ENST00000533087.5
ENST00000531312.5
ENST00000525165.5
ENST00000525326.5
ENST00000525546.5
ENST00000436153.6
ENST00000530781.5
dehydrodolichyl diphosphate synthase subunit
chr14_+_101964561 0.11 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
dynein cytoplasmic 1 heavy chain 1
chr6_-_89352706 0.11 ENST00000435041.3
ubiquitin conjugating enzyme E2 J1
chr3_+_50246888 0.11 ENST00000451956.1
G protein subunit alpha i2
chr9_+_15553002 0.11 ENST00000380701.8
coiled-coil domain containing 171
chr15_+_79311137 0.11 ENST00000424155.6
ENST00000536821.5
transmembrane p24 trafficking protein 3
chr9_+_111631354 0.11 ENST00000374294.3
DNAJC25-GNG10 readthrough
chr15_-_90102448 0.10 ENST00000330062.8
ENST00000559482.5
isocitrate dehydrogenase (NADP(+)) 2
chr20_+_32819942 0.10 ENST00000375571.6
microtubule associated protein RP/EB family member 1
chr4_+_8269744 0.10 ENST00000307358.7
ENST00000382512.3
HtrA serine peptidase 3
chr12_-_108731505 0.10 ENST00000261401.8
ENST00000552871.5
coronin 1C
chr7_+_128739395 0.10 ENST00000479257.5
calumenin
chr9_+_111631300 0.10 ENST00000313525.4
DnaJ heat shock protein family (Hsp40) member C25
chr4_+_8592750 0.10 ENST00000315782.6
ENST00000360986.9
carboxypeptidase Z
chr12_-_13981544 0.10 ENST00000609686.4
glutamate ionotropic receptor NMDA type subunit 2B
chr11_-_66289125 0.10 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
Yip1 interacting factor homolog A, membrane trafficking protein
chr3_-_10321041 0.10 ENST00000397109.7
ENST00000428626.5
ENST00000445064.1
ENST00000431352.1
ENST00000397117.5
ENST00000337354.8
ENST00000383801.6
ENST00000432213.1
ENST00000350697.8
SEC13 homolog, nuclear pore and COPII coat complex component
chr11_-_62832033 0.09 ENST00000377897.8
ENST00000394690.5
ENST00000294179.8
syntaxin 5
chr14_-_24195334 0.09 ENST00000530563.1
ENST00000528895.5
ENST00000528669.5
ENST00000532632.1
ENST00000261789.9
transmembrane 9 superfamily member 1
chr1_-_145859043 0.09 ENST00000369298.5
protein inhibitor of activated STAT 3
chr4_-_46390273 0.09 ENST00000515082.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr1_-_155173245 0.09 ENST00000497317.5
ENST00000482246.5
ENST00000295682.6
keratinocyte associated protein 2
chr1_-_145859061 0.09 ENST00000393045.7
protein inhibitor of activated STAT 3
chr1_-_21782991 0.09 ENST00000529637.5
ubiquitin specific peptidase 48
chr3_-_105869035 0.09 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr19_+_46601237 0.09 ENST00000597743.5
calmodulin 3
chr19_-_18919348 0.08 ENST00000349893.8
ENST00000351079.8
ENST00000600932.5
ENST00000262812.9
COPI coat complex subunit epsilon
chr17_+_47971105 0.08 ENST00000338399.9
ENST00000578018.5
ENST00000579175.5
CDK5 regulatory subunit associated protein 3
chr3_-_28348924 0.08 ENST00000414162.5
ENST00000420543.6
5-azacytidine induced 2
chr11_-_64878612 0.08 ENST00000320631.8
EH domain containing 1
chr8_-_63026179 0.08 ENST00000677919.1
gamma-glutamyl hydrolase
chr2_-_118014125 0.08 ENST00000319432.9
coiled-coil domain containing 93
chr2_-_118014035 0.08 ENST00000376300.7
coiled-coil domain containing 93
chr2_-_241315652 0.07 ENST00000310931.10
ENST00000413241.5
ENST00000423693.5
ENST00000428482.5
ENST00000420451.5
ENST00000417540.5
high density lipoprotein binding protein
chr2_-_69387130 0.07 ENST00000674438.1
glutamine--fructose-6-phosphate transaminase 1
chr1_+_222618075 0.07 ENST00000344922.10
MIA SH3 domain ER export factor 3
chr4_+_42397473 0.07 ENST00000319234.5
shisa family member 3
chr19_+_16077006 0.07 ENST00000586833.7
ENST00000642221.1
tropomyosin 4
chr19_-_54115626 0.07 ENST00000391759.6
TCF3 fusion partner
chrX_+_154398890 0.07 ENST00000406022.6
ribosomal protein L10
chr19_-_54115271 0.07 ENST00000391757.1
TCF3 fusion partner
chr2_-_20051610 0.07 ENST00000175091.5
lysosomal protein transmembrane 4 alpha
chr11_-_66289007 0.07 ENST00000431556.6
ENST00000528575.1
Yip1 interacting factor homolog A, membrane trafficking protein
chr15_-_74873310 0.07 ENST00000562363.5
ENST00000564529.1
ENST00000268099.13
secretory carrier membrane protein 2
chr3_-_177196451 0.06 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chrX_-_41922992 0.06 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
calcium/calmodulin dependent serine protein kinase
chr18_+_36829111 0.06 ENST00000280020.10
ENST00000592521.5
ENST00000587139.5
KIAA1328
chr11_+_47408582 0.06 ENST00000531974.5
ENST00000362021.9
ENST00000531419.5
ENST00000531865.5
ENST00000354884.8
solute carrier family 39 member 13
chr19_+_49851205 0.06 ENST00000601675.5
PTOV1 extended AT-hook containing adaptor protein
chr12_+_62466791 0.06 ENST00000641654.1
ENST00000546600.5
ENST00000393630.8
ENST00000552738.5
ENST00000393629.6
ENST00000552115.5
MON2 homolog, regulator of endosome-to-Golgi trafficking
chr7_+_128739292 0.06 ENST00000535011.6
ENST00000542996.6
ENST00000249364.9
ENST00000449187.6
calumenin
chr16_-_11797208 0.06 ENST00000571198.5
ENST00000572781.5
ENST00000355758.9
zinc finger CCCH-type containing 7A
chr12_-_132828823 0.06 ENST00000545875.4
ENST00000456883.6
ENST00000450791.7
ENST00000204726.8
golgin A3
chr11_-_40294089 0.05 ENST00000278198.2
leucine rich repeat containing 4C
chr9_+_99222258 0.05 ENST00000223641.5
SEC61 translocon subunit beta
chrX_-_153794494 0.05 ENST00000370092.7
ENST00000619865.4
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
chr6_-_109381739 0.05 ENST00000504373.2
CD164 molecule
chr7_-_6484057 0.05 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr2_+_27032938 0.05 ENST00000238788.14
ENST00000404032.7
transmembrane protein 214
chr22_-_30326877 0.05 ENST00000403477.7
TBC1 domain family member 10A
chr5_+_115841878 0.05 ENST00000316788.12
adaptor related protein complex 3 subunit sigma 1
chr17_-_15563428 0.05 ENST00000584811.5
ENST00000419890.3
ENST00000518321.6
ENST00000438826.7
ENST00000225576.7
ENST00000428082.6
ENST00000522212.6
trans-golgi network vesicle protein 23 homolog C
TVP23C-CDRT4 readthrough
chr7_+_100949525 0.05 ENST00000379458.9
ENST00000483366.5
mucin 3A, cell surface associated
chr18_-_36828939 0.05 ENST00000593035.5
ENST00000383056.7
ENST00000588909.1
ENST00000590337.5
ENST00000334295.9
tubulin polyglutamylase complex subunit 2
chr6_+_63211446 0.04 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr2_+_170929198 0.04 ENST00000234160.5
golgi reassembly stacking protein 2
chrX_+_153794635 0.04 ENST00000370086.8
ENST00000370085.3
signal sequence receptor subunit 4
chr4_-_120922648 0.04 ENST00000264808.8
PR/SET domain 5
chr19_+_48965304 0.04 ENST00000331825.11
ferritin light chain
chr22_-_30326923 0.04 ENST00000215790.12
TBC1 domain family member 10A
chr3_+_132659897 0.04 ENST00000493720.6
ubiquitin like modifier activating enzyme 5
chr18_-_36828771 0.04 ENST00000589049.5
ENST00000587129.5
ENST00000590842.5
tubulin polyglutamylase complex subunit 2
chr19_+_49851136 0.04 ENST00000391842.5
PTOV1 extended AT-hook containing adaptor protein
chr4_-_47914596 0.04 ENST00000381538.7
ENST00000329043.7
nuclear transcription factor, X-box binding like 1
chr3_+_128052390 0.03 ENST00000481210.5
ENST00000243253.8
SEC61 translocon subunit alpha 1
chr14_+_95876385 0.03 ENST00000504119.1
TCL1 upstream neural differentiation-associated RNA
chr11_-_207221 0.03 ENST00000486280.1
ENST00000332865.10
ENST00000529614.6
ENST00000325147.13
ENST00000410108.5
ENST00000382762.7
Bet1 golgi vesicular membrane trafficking protein like
chr19_+_49851173 0.03 ENST00000599732.5
PTOV1 extended AT-hook containing adaptor protein
chr9_+_35749274 0.03 ENST00000378078.5
RGP1 homolog, RAB6A GEF complex partner 1
chr3_-_28348629 0.03 ENST00000334100.10
5-azacytidine induced 2
chr2_-_99336306 0.03 ENST00000264255.8
ENST00000409434.5
ENST00000434323.5
thioredoxin domain containing 9
chrX_+_70062457 0.03 ENST00000338352.3
OTU deubiquitinase 6A
chr12_+_48328980 0.02 ENST00000335017.1
H1.7 linker histone
chr13_-_45341086 0.02 ENST00000309246.9
ENST00000379060.8
ENST00000379055.5
ENST00000527226.2
ENST00000530705.6
ENST00000379056.5
ENST00000616577.4
tumor protein, translationally-controlled 1
chr19_+_49850687 0.02 ENST00000594151.5
ENST00000600603.5
ENST00000601638.5
PTOV1 extended AT-hook containing adaptor protein

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 GO:0043589 skin morphogenesis(GO:0043589)
0.3 0.8 GO:0000103 sulfate assimilation(GO:0000103)
0.2 2.4 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 1.2 GO:0021678 third ventricle development(GO:0021678)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.3 GO:0060435 bronchiole development(GO:0060435)
0.1 1.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.5 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 1.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.5 GO:0035934 corticosterone secretion(GO:0035934)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.4 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.3 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.6 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385) regulation of metaphase plate congression(GO:0090235)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.4 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 0.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 1.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0002081 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 5.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 1.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.1 0.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.2 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis