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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZBTB18

Z-value: 1.84

Motif logo

Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ENSG00000179456.10 zinc finger and BTB domain containing 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB18hg38_v1_chr1_+_244051275_244051291-0.186.7e-01Click!

Activity profile of ZBTB18 motif

Sorted Z-values of ZBTB18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_188974364 3.43 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr1_-_168729187 1.91 ENST00000367817.4
dermatopontin
chr2_+_151357583 1.78 ENST00000243347.5
TNF alpha induced protein 6
chr2_+_33134579 1.62 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr2_+_33134620 1.58 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr12_+_1629197 1.28 ENST00000397196.7
Wnt family member 5B
chr2_-_162242998 1.11 ENST00000627638.2
ENST00000447386.5
fibroblast activation protein alpha
chr11_+_15114912 1.09 ENST00000379556.8
INSC spindle orientation adaptor protein
chr2_-_162243375 1.07 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr15_-_89815332 1.06 ENST00000559874.2
alanyl aminopeptidase, membrane
chr15_-_89814845 1.05 ENST00000679248.1
ENST00000300060.7
ENST00000560137.2
alanyl aminopeptidase, membrane
chrX_+_9912434 1.02 ENST00000418909.6
shroom family member 2
chrX_+_150361559 0.93 ENST00000262858.8
mastermind like domain containing 1
chr17_-_19748341 0.91 ENST00000395555.7
aldehyde dehydrogenase 3 family member A1
chr17_-_19748285 0.91 ENST00000570414.1
ENST00000225740.11
aldehyde dehydrogenase 3 family member A1
chr17_-_69141878 0.91 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr1_-_16980607 0.90 ENST00000375535.4
microfibril associated protein 2
chrX_-_102516714 0.89 ENST00000289373.5
thymosin beta 15A
chr17_-_19748355 0.88 ENST00000494157.6
aldehyde dehydrogenase 3 family member A1
chr1_-_153545793 0.82 ENST00000354332.8
ENST00000368716.9
S100 calcium binding protein A4
chr13_-_33205997 0.81 ENST00000399365.7
StAR related lipid transfer domain containing 13
chr17_-_15265230 0.70 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
peripheral myelin protein 22
chr1_+_77888490 0.69 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr1_+_77888612 0.67 ENST00000334785.12
nexilin F-actin binding protein
chr18_+_6834473 0.67 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
Rho GTPase activating protein 28
chr11_+_5389377 0.60 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chrX_+_65588368 0.60 ENST00000609672.5
moesin
chr7_+_101127095 0.54 ENST00000223095.5
serpin family E member 1
chr7_+_90596281 0.53 ENST00000380050.8
cyclin dependent kinase 14
chr3_-_160449721 0.50 ENST00000479460.5
tripartite motif containing 59
chrX_+_103776493 0.46 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
proteolipid protein 1
chrX_+_103776831 0.46 ENST00000621218.5
ENST00000619236.1
proteolipid protein 1
chr19_+_58305319 0.45 ENST00000413518.5
ENST00000427361.5
ENST00000610038.5
ENST00000608070.5
ENST00000609864.5
endogenous retrovirus group K3 member 1
chrX_+_43656289 0.43 ENST00000338702.4
monoamine oxidase A
chr12_-_104050112 0.42 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
glycosyltransferase 8 domain containing 2
chr2_-_229232039 0.42 ENST00000354069.6
phosphotyrosine interaction domain containing 1
chr1_+_37556913 0.42 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr19_+_38390055 0.39 ENST00000587947.5
ENST00000338502.8
sprouty related EVH1 domain containing 3
chr9_+_94726657 0.39 ENST00000375315.8
ENST00000277198.6
ENST00000297979.9
aminopeptidase O (putative)
chr3_-_160449530 0.39 ENST00000494486.1
tripartite motif containing 59
chr6_-_30556477 0.38 ENST00000376621.8
G protein nucleolar 1 (putative)
chr12_-_55728640 0.38 ENST00000551173.5
ENST00000420846.7
CD63 molecule
chr1_-_33182030 0.36 ENST00000291416.10
tripartite motif containing 62
chr16_-_31065011 0.33 ENST00000539836.3
ENST00000535577.5
ENST00000442862.2
zinc finger protein 668
chr1_-_156677400 0.32 ENST00000368223.4
nestin
chr12_+_25973748 0.30 ENST00000542865.5
Ras association domain family member 8
chr1_+_211259932 0.30 ENST00000367005.8
REST corepressor 3
chr2_+_201129318 0.30 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr11_-_69013233 0.29 ENST00000309099.7
ENST00000320913.6
MAS related GPR family member F
chr15_+_75043263 0.29 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr12_-_55727796 0.28 ENST00000550776.5
CD63 molecule
chrX_+_154542194 0.28 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr11_-_62556230 0.27 ENST00000530285.5
AHNAK nucleoprotein
chr8_+_39107529 0.27 ENST00000399831.7
ENST00000437682.6
ENST00000519315.5
ADAM metallopeptidase domain 32
chr12_-_55727828 0.27 ENST00000546939.5
CD63 molecule
chr12_-_53727476 0.27 ENST00000549784.5
ENST00000262059.8
calcium binding and coiled-coil domain 1
chr16_-_67150951 0.27 ENST00000449549.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr17_-_78360066 0.26 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chr19_+_40613416 0.26 ENST00000599724.5
ENST00000597071.5
latent transforming growth factor beta binding protein 4
chr9_-_13165442 0.25 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr22_-_19881369 0.24 ENST00000462330.5
thioredoxin reductase 2
chr12_-_53499444 0.24 ENST00000547488.6
mitogen-activated protein kinase kinase kinase 12
chr12_-_53499615 0.24 ENST00000267079.6
mitogen-activated protein kinase kinase kinase 12
chr11_-_123195208 0.24 ENST00000448775.4
CXADR like membrane protein
chr5_+_119354771 0.24 ENST00000503646.1
TNF alpha induced protein 8
chr3_+_49007062 0.24 ENST00000395474.7
ENST00000610967.4
ENST00000429900.6
WD repeat domain 6
chr9_+_128920966 0.23 ENST00000428610.5
ENST00000372592.8
phytanoyl-CoA dioxygenase domain containing 1
chr11_-_69013356 0.23 ENST00000441623.1
MAS related GPR family member F
chrX_+_100644183 0.23 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr2_-_85602681 0.23 ENST00000334462.10
ENST00000306353.7
transmembrane protein 150A
chr19_-_10231293 0.23 ENST00000646641.1
sphingosine-1-phosphate receptor 2
chr17_-_63972918 0.22 ENST00000435607.3
sodium voltage-gated channel alpha subunit 4
chr1_+_53062052 0.22 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
podocan
chr3_+_100492548 0.20 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
transmembrane protein 45A
chr3_+_184176778 0.20 ENST00000439647.5
adaptor related protein complex 2 subunit mu 1
chr15_-_56918571 0.20 ENST00000559000.6
novel protein
chr15_+_51377247 0.20 ENST00000396399.6
gliomedin
chr16_-_49664225 0.20 ENST00000535559.5
zinc finger protein 423
chr6_-_152983031 0.20 ENST00000229758.8
F-box protein 5
chr22_+_41976760 0.19 ENST00000396426.7
ENST00000406029.5
septin 3
chr10_-_103153609 0.19 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr22_+_41976933 0.19 ENST00000396425.7
septin 3
chr19_+_39412650 0.19 ENST00000425673.6
pleckstrin homology and RhoGEF domain containing G2
chr3_+_184176949 0.19 ENST00000432591.5
ENST00000431779.5
ENST00000621863.4
adaptor related protein complex 2 subunit mu 1
chr16_-_29899532 0.18 ENST00000308713.9
ENST00000617533.5
seizure related 6 homolog like 2
chr16_-_30382805 0.18 ENST00000321367.7
ENST00000652617.1
septin 1
chr18_+_54828406 0.18 ENST00000262094.10
RAB27B, member RAS oncogene family
chr22_-_19881163 0.18 ENST00000485358.5
thioredoxin reductase 2
chr20_+_59300402 0.18 ENST00000311585.11
ENST00000371028.6
endothelin 3
chr14_+_64503943 0.18 ENST00000556965.1
ENST00000554015.5
zinc finger and BTB domain containing 1
chr5_-_149944744 0.17 ENST00000255266.10
ENST00000617647.4
ENST00000613228.1
phosphodiesterase 6A
chr17_+_62627628 0.17 ENST00000303375.10
mannose receptor C type 2
chr16_-_29899245 0.17 ENST00000537485.5
seizure related 6 homolog like 2
chr2_-_85602351 0.17 ENST00000409668.1
transmembrane protein 150A
chr20_+_58907981 0.17 ENST00000656419.1
GNAS complex locus
chr17_+_50561010 0.16 ENST00000360761.8
ENST00000354983.8
ENST00000352832.9
calcium voltage-gated channel subunit alpha1 G
chr16_-_87334273 0.16 ENST00000568879.1
novel protein
chr17_+_50560703 0.16 ENST00000359106.10
calcium voltage-gated channel subunit alpha1 G
chr20_+_59300589 0.16 ENST00000337938.7
ENST00000371025.7
endothelin 3
chr20_+_59300703 0.16 ENST00000395654.3
endothelin 3
chr12_-_55728339 0.15 ENST00000552754.5
CD63 molecule
chr3_-_160449752 0.15 ENST00000496222.1
ENST00000471396.1
ENST00000471155.5
ENST00000309784.9
tripartite motif containing 59
chr10_-_22003678 0.15 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr14_-_23057530 0.15 ENST00000397359.7
ENST00000610348.1
cadherin 24
chr19_+_50432885 0.15 ENST00000357701.6
myosin binding protein C2
chr17_-_33293247 0.15 ENST00000225823.7
acid sensing ion channel subunit 2
chr12_+_52079700 0.15 ENST00000546390.2
small integral membrane protein 41
chr14_-_23057506 0.15 ENST00000487137.7
cadherin 24
chr12_-_49828394 0.15 ENST00000335999.7
NCK associated protein 5 like
chr3_-_52239082 0.15 ENST00000499914.2
ENST00000678838.1
ENST00000305533.10
ENST00000678330.1
twinfilin actin binding protein 2
chr14_+_64504574 0.14 ENST00000358738.3
zinc finger and BTB domain containing 1
chr4_+_155903688 0.14 ENST00000536354.3
tryptophan 2,3-dioxygenase
chr18_+_24155938 0.14 ENST00000582229.1
calcium binding tyrosine phosphorylation regulated
chr2_-_98731063 0.14 ENST00000393487.6
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr5_-_151924824 0.14 ENST00000455880.2
glycine receptor alpha 1
chr2_-_1744442 0.13 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr9_+_97412062 0.13 ENST00000355295.5
tudor domain containing 7
chr5_+_119476530 0.13 ENST00000645099.1
ENST00000513628.5
hydroxysteroid 17-beta dehydrogenase 4
chr5_-_151924846 0.13 ENST00000274576.9
glycine receptor alpha 1
chr7_-_135748712 0.13 ENST00000415751.1
family with sequence similarity 180 member A
chr1_-_112618204 0.13 ENST00000369664.1
suppression of tumorigenicity 7 like
chr17_+_34255274 0.13 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2
chr20_+_59300547 0.12 ENST00000644821.1
endothelin 3
chr1_-_151909555 0.12 ENST00000489410.1
thioesterase superfamily member 4
chr9_+_70043840 0.12 ENST00000377182.5
MAM domain containing 2
chr14_+_78170336 0.12 ENST00000634499.2
ENST00000335750.7
neurexin 3
chr16_+_6019663 0.12 ENST00000422070.8
RNA binding fox-1 homolog 1
chr14_+_67240713 0.12 ENST00000677382.1
membrane palmitoylated protein 5
chr4_-_151227881 0.11 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr14_-_77271200 0.11 ENST00000298352.5
neuroglobin
chr12_-_47725483 0.11 ENST00000422538.8
endonuclease, poly(U) specific
chr7_-_120857124 0.11 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr1_-_224330121 0.11 ENST00000469968.5
ENST00000436927.5
ENST00000469075.5
ENST00000488718.5
ENST00000340871.8
ENST00000492281.5
ENST00000391875.6
ENST00000281701.11
ENST00000461546.2
ENST00000482491.5
nuclear VCP like
chr6_+_160121859 0.10 ENST00000324965.8
ENST00000457470.6
solute carrier family 22 member 1
chr1_-_151909501 0.09 ENST00000368814.8
thioesterase superfamily member 4
chr11_+_73289403 0.09 ENST00000535931.2
ENST00000544437.6
pyrimidinergic receptor P2Y6
chr12_-_47725558 0.09 ENST00000229003.7
endonuclease, poly(U) specific
chr11_+_72189659 0.08 ENST00000393681.6
folate receptor alpha
chr1_+_8945858 0.08 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
carbonic anhydrase 6
chr15_+_56918763 0.07 ENST00000557843.5
transcription factor 12
chr14_+_67241278 0.07 ENST00000676464.1
membrane palmitoylated protein 5
chr6_+_160121809 0.07 ENST00000366963.9
solute carrier family 22 member 1
chr21_-_34511243 0.07 ENST00000399284.1
potassium voltage-gated channel subfamily E regulatory subunit 1
chr21_-_34511317 0.07 ENST00000611936.1
ENST00000337385.7
potassium voltage-gated channel subfamily E regulatory subunit 1
chr14_+_64504743 0.06 ENST00000683701.1
zinc finger and BTB domain containing 1
chr11_+_94493963 0.06 ENST00000540349.1
ENST00000544612.6
ENST00000535502.1
ENST00000545130.5
ENST00000544253.1
ENST00000541144.1
ankyrin repeat domain 49
chr18_+_3448456 0.06 ENST00000549780.5
TGFB induced factor homeobox 1
chr19_+_9140377 0.06 ENST00000360385.7
ENST00000247956.11
zinc finger protein 317
chr15_+_31326807 0.06 ENST00000307145.4
Kruppel like factor 13
chr3_+_159852933 0.06 ENST00000482804.1
schwannomin interacting protein 1
chr20_-_63361337 0.05 ENST00000370263.9
cholinergic receptor nicotinic alpha 4 subunit
chr9_+_122375286 0.05 ENST00000373698.7
prostaglandin-endoperoxide synthase 1
chr1_+_186296267 0.05 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
proteoglycan 4
chr11_-_63917129 0.05 ENST00000301459.5
REST corepressor 2
chr16_-_29863117 0.05 ENST00000566113.5
ENST00000569956.5
ENST00000570016.5
ENST00000219789.11
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr13_+_113122791 0.04 ENST00000375559.8
ENST00000409306.5
ENST00000375551.7
coagulation factor X
chr6_+_112236806 0.04 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chr20_+_31879798 0.03 ENST00000620043.4
tubulin tyrosine ligase like 9
chr2_-_157874976 0.03 ENST00000682025.1
ENST00000683487.1
ENST00000682300.1
ENST00000683441.1
ENST00000684595.1
ENST00000683426.1
ENST00000683820.1
ENST00000263640.7
activin A receptor type 1
chr3_-_44510602 0.02 ENST00000436261.6
zinc finger protein 852
chr4_+_164877164 0.02 ENST00000507152.6
ENST00000515275.1
apelin receptor early endogenous ligand
chr19_+_42302098 0.02 ENST00000598490.1
ENST00000341747.8
proline rich 19
chr8_+_24384275 0.02 ENST00000256412.8
ADAM like decysin 1
chr10_-_7787946 0.02 ENST00000379562.9
Kin17 DNA and RNA binding protein
chr6_+_162727941 0.02 ENST00000366888.6
parkin coregulated
chr8_+_24384455 0.02 ENST00000522298.1
ADAM like decysin 1
chr10_+_70052582 0.02 ENST00000676699.1
macroH2A.2 histone
chr17_+_44957907 0.01 ENST00000678938.1
N-myristoyltransferase 1
chr15_-_74209019 0.01 ENST00000323940.9
signaling receptor and transporter of retinol STRA6
chrX_-_48196763 0.01 ENST00000311798.5
ENST00000347757.6
SSX family member 5
chr14_-_91244669 0.01 ENST00000650645.1
G protein-coupled receptor 68
chr15_-_31161157 0.01 ENST00000542188.5
transient receptor potential cation channel subfamily M member 1
chr20_+_3732675 0.01 ENST00000254963.7
ENST00000399701.1
heat shock protein family A (Hsp70) member 12B
chr10_-_93482194 0.00 ENST00000358334.9
ENST00000371488.3
myoferlin
chr3_+_30606574 0.00 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chr13_-_60013178 0.00 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr17_-_43022350 0.00 ENST00000587173.5
ENST00000355653.8
vesicle amine transport 1
chr11_+_65638085 0.00 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.5 3.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 3.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.9 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.4 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.4 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.3 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 2.1 GO:0043476 pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482)
0.1 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 1.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.2 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.8 GO:0030728 ovulation(GO:0030728)
0.0 0.7 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 2.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 1.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.7 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 2.7 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.3 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.1 GO:0042989 regulation of microvillus length(GO:0032532) sequestering of actin monomers(GO:0042989)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0061445 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 4.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0097229 sperm end piece(GO:0097229)
0.0 1.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0050436 microfibril binding(GO:0050436)
0.4 2.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 3.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 2.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 7.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription