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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZBTB3

Z-value: 0.74

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Transcription factors associated with ZBTB3

Gene Symbol Gene ID Gene Info
ENSG00000185670.9 zinc finger and BTB domain containing 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB3hg38_v1_chr11_-_62754141_627541840.591.3e-01Click!

Activity profile of ZBTB3 motif

Sorted Z-values of ZBTB3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_159171607 0.98 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
cell adhesion molecule 3
chr14_-_91946989 0.93 ENST00000556154.5
fibulin 5
chr14_-_91947654 0.89 ENST00000342058.9
fibulin 5
chr14_-_91947383 0.84 ENST00000267620.14
fibulin 5
chr11_-_83071819 0.26 ENST00000524635.1
ENST00000526205.5
ENST00000533486.5
ENST00000533276.6
ENST00000527633.6
RAB30, member RAS oncogene family
chr12_+_54854505 0.25 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr11_-_83071917 0.22 ENST00000534141.5
RAB30, member RAS oncogene family
chr12_-_119803383 0.20 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr19_+_35030626 0.19 ENST00000638536.1
sodium voltage-gated channel beta subunit 1
chr19_+_35030438 0.19 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chr19_-_39532809 0.18 ENST00000326282.5
EP300 interacting inhibitor of differentiation 2B
chr12_-_119804298 0.17 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr19_-_6670151 0.16 ENST00000675206.1
TNF superfamily member 14
chr19_-_6670117 0.15 ENST00000245912.7
TNF superfamily member 14
chr8_+_22567038 0.15 ENST00000523348.1
sorbin and SH3 domain containing 3
chr5_+_170861990 0.14 ENST00000523189.6
RAN binding protein 17
chr16_+_53130921 0.14 ENST00000564845.5
chromodomain helicase DNA binding protein 9
chr4_-_5893075 0.14 ENST00000324989.12
collapsin response mediator protein 1
chr4_-_17781613 0.13 ENST00000265018.4
family with sequence similarity 184 member B
chr6_+_44158807 0.13 ENST00000532171.5
ENST00000398776.2
calpain 11
chr5_+_112738331 0.12 ENST00000512211.6
APC regulator of WNT signaling pathway
chr12_+_48183602 0.11 ENST00000316554.5
coiled-coil domain containing 184
chrX_+_135032346 0.10 ENST00000257013.9
retrotransposon Gag like 8C
chr8_-_42768602 0.10 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr17_-_41467386 0.10 ENST00000225899.4
keratin 32
chr11_-_130916437 0.10 ENST00000533214.1
ENST00000528555.5
ENST00000530356.5
ENST00000265909.9
sorting nexin 19
chr1_-_169586471 0.09 ENST00000367797.9
coagulation factor V
chr10_+_68560317 0.09 ENST00000373644.5
tet methylcytosine dioxygenase 1
chr5_+_141135199 0.09 ENST00000231134.8
ENST00000623915.1
protocadherin beta 5
chr12_+_53097656 0.09 ENST00000301464.4
insulin like growth factor binding protein 6
chr1_-_169586539 0.09 ENST00000367796.3
coagulation factor V
chr8_-_42768781 0.09 ENST00000276410.7
cholinergic receptor nicotinic alpha 6 subunit
chr7_+_134891566 0.08 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chr15_-_74367637 0.08 ENST00000268053.11
ENST00000416978.1
cytochrome P450 family 11 subfamily A member 1
chr17_+_77127865 0.08 ENST00000586429.5
SEC14 like lipid binding 1
chr2_+_42169434 0.08 ENST00000401738.3
EMAP like 4
chr2_+_240691851 0.06 ENST00000429564.1
ENST00000337801.9
aquaporin 12A
chr2_+_42169332 0.06 ENST00000402711.6
ENST00000318522.10
EMAP like 4
chr5_+_139273752 0.06 ENST00000509990.5
ENST00000506147.5
ENST00000512107.5
matrin 3
chr6_-_119349754 0.06 ENST00000368468.4
mannosidase alpha class 1A member 1
chr3_-_195442853 0.06 ENST00000635383.1
ENST00000439666.1
ENST00000618471.4
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr18_+_34493289 0.05 ENST00000682923.1
ENST00000596745.5
ENST00000283365.14
ENST00000315456.10
ENST00000598774.6
ENST00000684266.1
ENST00000683092.1
ENST00000683379.1
ENST00000684359.1
dystrobrevin alpha
chr2_-_153478753 0.05 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr2_-_2326378 0.05 ENST00000647618.1
myelin transcription factor 1 like
chr5_+_77086682 0.05 ENST00000643365.1
ENST00000645183.1
ENST00000645374.1
ENST00000647364.1
ENST00000643848.1
ENST00000643603.1
ENST00000645459.1
ENST00000643269.1
ENST00000503969.6
ENST00000646262.1
ZBED3 antisense RNA 1
phosphodiesterase 8B
chr7_+_134891400 0.05 ENST00000393118.6
caldesmon 1
chr6_-_41154326 0.05 ENST00000426005.6
ENST00000437044.2
ENST00000373127.8
triggering receptor expressed on myeloid cells like 1
chr16_+_89720980 0.05 ENST00000289816.9
ENST00000568064.5
zinc finger protein 276
chr6_+_29306626 0.05 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr15_+_64136330 0.05 ENST00000560861.1
sorting nexin 1
chr3_-_195442977 0.05 ENST00000326793.11
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr1_+_244835616 0.04 ENST00000366528.3
ENST00000411948.7
cytochrome c oxidase assembly factor COX20
chr16_-_2135898 0.04 ENST00000262304.9
ENST00000423118.5
polycystin 1, transient receptor potential channel interacting
chr1_-_149936816 0.04 ENST00000439741.4
myotubularin related protein 11
chr10_-_116273606 0.04 ENST00000682743.1
GDNF family receptor alpha 1
chr20_-_56497608 0.04 ENST00000617620.1
glucosaminyl (N-acetyl) transferase family member 7
chr1_-_120051714 0.04 ENST00000579475.7
notch receptor 2
chrX_-_86047527 0.04 ENST00000615443.1
ENST00000357749.7
CHM Rab escort protein
chr5_+_76083398 0.04 ENST00000322285.7
synaptic vesicle glycoprotein 2C
chr20_+_63658286 0.04 ENST00000360203.11
ENST00000508582.7
ENST00000318100.9
ENST00000356810.5
regulator of telomere elongation helicase 1
chr11_+_123358416 0.04 ENST00000638157.1
GRAM domain containing 1B
chr2_-_151971750 0.04 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr14_+_60249387 0.04 ENST00000325658.3
protein phosphatase, Mg2+/Mn2+ dependent 1A
chr1_+_171257930 0.03 ENST00000354841.4
flavin containing dimethylaniline monoxygenase 1
chr5_+_76083360 0.03 ENST00000502798.7
synaptic vesicle glycoprotein 2C
chr1_+_154257071 0.03 ENST00000428595.1
ubiquitin associated protein 2 like
chr2_-_85668172 0.03 ENST00000428225.5
ENST00000519937.7
surfactant protein B
chr5_+_75512058 0.03 ENST00000514296.5
DNA polymerase kappa
chr9_+_71911468 0.03 ENST00000377031.7
chromosome 9 open reading frame 85
chr15_+_32030481 0.03 ENST00000454250.7
ENST00000675428.1
ENST00000637552.1
cholinergic receptor nicotinic alpha 7 subunit
chr11_+_67240047 0.03 ENST00000530342.2
lysine demethylase 2A
chr10_+_44911316 0.03 ENST00000544540.5
ENST00000389583.5
transmembrane protein 72
chr21_+_43789522 0.02 ENST00000497547.2
ribosomal RNA processing 1
chr17_-_7627803 0.02 ENST00000573566.1
ENST00000269298.10
spermidine/spermine N1-acetyltransferase family member 2
chr7_+_23680130 0.02 ENST00000409192.7
ENST00000409653.5
ENST00000409994.3
ENST00000344962.9
family with sequence similarity 221 member A
chr12_+_54325120 0.02 ENST00000549043.5
ENST00000552218.5
ENST00000262061.7
ENST00000553231.5
ENST00000552362.5
ENST00000455864.6
ENST00000549116.5
ENST00000551779.5
COPI coat complex subunit zeta 1
chr15_+_69160620 0.02 ENST00000261858.7
glucuronic acid epimerase
chr1_+_160190567 0.02 ENST00000368078.8
calsequestrin 1
chr16_-_19884828 0.02 ENST00000300571.7
ENST00000570142.5
ENST00000562469.5
G protein-coupled receptor class C group 5 member B
chr21_-_46605073 0.02 ENST00000291700.9
ENST00000367071.4
S100 calcium binding protein B
chr2_-_2326210 0.02 ENST00000647755.1
myelin transcription factor 1 like
chr11_+_64924673 0.02 ENST00000164133.7
ENST00000532850.1
protein phosphatase 2 regulatory subunit B'beta
chr17_-_10421944 0.02 ENST00000403437.2
myosin heavy chain 8
chr1_-_155300979 0.01 ENST00000392414.7
pyruvate kinase L/R
chr14_-_106803221 0.01 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr9_+_122370523 0.01 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr19_-_39435936 0.01 ENST00000339471.8
ENST00000601655.5
ENST00000251453.8
ribosomal protein S16
chr19_+_52274443 0.01 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
zinc finger protein 766
chr5_+_75511756 0.01 ENST00000241436.8
DNA polymerase kappa
chr19_-_39435910 0.01 ENST00000599539.5
ribosomal protein S16
chr15_+_32030506 0.01 ENST00000306901.9
ENST00000636440.1
cholinergic receptor nicotinic alpha 7 subunit
chr19_-_39435627 0.01 ENST00000599705.1
ribosomal protein S16
chr3_+_178558700 0.01 ENST00000432997.5
ENST00000455865.5
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr19_-_55038256 0.01 ENST00000417454.5
ENST00000310373.7
ENST00000333884.2
glycoprotein VI platelet
chr3_+_98531965 0.01 ENST00000284311.5
G protein-coupled receptor 15
chr18_+_12407896 0.01 ENST00000590956.5
ENST00000336990.8
ENST00000440960.6
ENST00000588729.5
PRELI domain containing 3A
chrX_+_153072454 0.01 ENST00000421798.5
PNMA family member 6A
chr3_-_52826834 0.01 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chr12_-_62192762 0.01 ENST00000416284.8
TAFA chemokine like family member 2
chr6_-_46170939 0.00 ENST00000230565.3
ENST00000371383.7
ectonucleotide pyrophosphatase/phosphodiesterase family member 5
chr5_+_114362043 0.00 ENST00000673685.1
potassium calcium-activated channel subfamily N member 2
chrX_+_71144818 0.00 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
neuroligin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0072218 ascending thin limb development(GO:0072021) distal tubule morphogenesis(GO:0072156) metanephric ascending thin limb development(GO:0072218) metanephric proximal tubule development(GO:0072237)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway