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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZFHX3

Z-value: 0.16

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Transcription factors associated with ZFHX3

Gene Symbol Gene ID Gene Info
ENSG00000140836.17 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZFHX3hg38_v1_chr16_-_73048104_73048136-0.216.3e-01Click!

Activity profile of ZFHX3 motif

Sorted Z-values of ZFHX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_73481737 0.14 ENST00000226355.5
afamin
chr3_-_114758940 0.13 ENST00000464560.5
zinc finger and BTB domain containing 20
chr4_-_154590735 0.12 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr7_+_130486171 0.08 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr7_+_130486324 0.08 ENST00000427521.6
ENST00000378576.9
mesoderm specific transcript
chrX_-_32155462 0.08 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr14_-_100569780 0.08 ENST00000355173.7
brain enriched guanylate kinase associated
chr1_-_247758680 0.07 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr8_+_103819244 0.07 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr8_-_69833338 0.07 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr9_-_121050264 0.06 ENST00000223642.3
complement C5
chr3_-_165078480 0.06 ENST00000264382.8
sucrase-isomaltase
chr6_-_29045175 0.05 ENST00000377175.2
olfactory receptor family 2 subfamily W member 1
chr5_-_35195236 0.05 ENST00000509839.5
prolactin receptor
chr6_+_29111560 0.05 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr19_-_58353482 0.05 ENST00000263100.8
alpha-1-B glycoprotein
chr12_+_53954870 0.05 ENST00000243103.4
homeobox C12
chr14_+_94561435 0.05 ENST00000557004.6
ENST00000555095.5
ENST00000298841.5
ENST00000554220.5
ENST00000553780.5
serpin family A member 4
serpin family A member 5
chr1_+_159587817 0.05 ENST00000255040.3
amyloid P component, serum
chr18_-_55422306 0.04 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr7_-_100428657 0.04 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr2_-_60553409 0.04 ENST00000358510.6
ENST00000643004.1
BAF chromatin remodeling complex subunit BCL11A
chr6_-_154430495 0.04 ENST00000424998.3
CNKSR family member 3
chr8_-_144529048 0.04 ENST00000527462.1
ENST00000313465.5
ENST00000524821.6
chromosome 8 open reading frame 82
chr15_+_76336755 0.04 ENST00000290759.9
ISL LIM homeobox 2
chr2_-_60553558 0.04 ENST00000642439.1
ENST00000356842.9
BAF chromatin remodeling complex subunit BCL11A
chr4_-_99435134 0.04 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_157503339 0.04 ENST00000392833.6
ventricular zone expressed PH domain containing 1
chr3_-_157503375 0.04 ENST00000362010.7
ventricular zone expressed PH domain containing 1
chr22_+_38705922 0.03 ENST00000216044.10
GTP binding protein 1
chrX_+_103376389 0.03 ENST00000372645.3
ENST00000372635.1
brain expressed X-linked 3
chr5_+_119354771 0.03 ENST00000503646.1
TNF alpha induced protein 8
chr14_+_39233908 0.03 ENST00000280082.4
MIA SH3 domain ER export factor 2
chr12_+_130953898 0.03 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr2_-_87021844 0.03 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr4_-_151227881 0.03 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr4_-_148444674 0.03 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr4_+_3441960 0.03 ENST00000382774.8
ENST00000511533.1
HGF activator
chr15_+_58431985 0.03 ENST00000433326.2
ENST00000299022.10
lipase C, hepatic type
chr11_+_8019193 0.03 ENST00000534099.5
TUB bipartite transcription factor
chr2_+_184598520 0.03 ENST00000302277.7
zinc finger protein 804A
chr6_-_116060859 0.03 ENST00000606080.2
fyn related Src family tyrosine kinase
chr2_-_2324642 0.02 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chr3_+_35680994 0.02 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr14_+_64704380 0.02 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr5_+_141245384 0.02 ENST00000623671.1
ENST00000231173.6
protocadherin beta 15
chr17_+_17782108 0.02 ENST00000395774.1
retinoic acid induced 1
chr9_-_123184233 0.02 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr1_-_160579439 0.02 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84 molecule
chr18_+_34976928 0.02 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr3_-_157503574 0.02 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr3_-_39280021 0.02 ENST00000399220.3
C-X3-C motif chemokine receptor 1
chr17_+_7407838 0.02 ENST00000302926.7
neuroligin 2
chr4_+_70592253 0.02 ENST00000322937.10
ENST00000613447.4
ameloblastin
chr12_-_101407727 0.02 ENST00000539055.5
ENST00000551688.1
ENST00000551671.5
ENST00000261636.13
ADP ribosylation factor like GTPase 1
chr2_-_60553618 0.02 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BAF chromatin remodeling complex subunit BCL11A
chr11_+_5389377 0.02 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr6_+_47781982 0.02 ENST00000489301.6
ENST00000638973.1
ENST00000371211.6
ENST00000393699.2
opsin 5
chr20_+_43558968 0.02 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
serum/glucocorticoid regulated kinase 2
chr2_+_233712905 0.02 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr12_-_7665897 0.02 ENST00000229304.5
apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr12_-_68159732 0.02 ENST00000229135.4
interferon gamma
chr2_+_87748087 0.02 ENST00000359481.9
plasminogen like B2
chr6_-_127918604 0.01 ENST00000537166.5
thymocyte selection associated
chr6_+_28349907 0.01 ENST00000252211.7
ENST00000341464.9
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr2_-_2324323 0.01 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr17_-_40999903 0.01 ENST00000391587.3
keratin associated protein 3-2
chr6_-_127918540 0.01 ENST00000368250.5
thymocyte selection associated
chr11_-_61920267 0.01 ENST00000531922.2
ENST00000301773.9
RAB3A interacting protein like 1
chr2_+_233729042 0.01 ENST00000482026.6
UDP glucuronosyltransferase family 1 member A3
chr22_-_30246739 0.01 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr6_+_160702238 0.01 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr2_+_233718734 0.01 ENST00000373409.8
UDP glucuronosyltransferase family 1 member A4
chr1_-_66801276 0.01 ENST00000304526.3
insulin like 5
chr6_+_157036315 0.01 ENST00000637904.1
AT-rich interaction domain 1B
chr4_+_99574812 0.01 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chrX_-_15601077 0.01 ENST00000680121.1
angiotensin I converting enzyme 2
chr20_-_7940444 0.01 ENST00000378789.4
hydroxyacid oxidase 1
chr12_+_53441724 0.01 ENST00000551003.5
ENST00000429243.7
ENST00000549068.5
ENST00000549740.5
ENST00000546581.5
ENST00000549581.5
ENST00000547368.5
ENST00000379786.8
ENST00000551945.5
ENST00000547717.1
proline rich 13
novel transcript
chr6_-_32407123 0.01 ENST00000374993.4
ENST00000544175.2
ENST00000454136.7
ENST00000446536.2
butyrophilin like 2
chr3_-_49029378 0.01 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr8_-_140764386 0.01 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr6_-_30932147 0.01 ENST00000359086.4
surfactant associated 2
chrX_+_16650155 0.01 ENST00000380200.3
S100 calcium binding protein G
chr11_+_74748831 0.01 ENST00000299563.5
ring finger protein 169
chrX_+_85003863 0.01 ENST00000373173.7
apolipoprotein O like
chr6_-_160664270 0.00 ENST00000316300.10
lipoprotein(a)
chr22_-_30574572 0.00 ENST00000402369.5
galactose-3-O-sulfotransferase 1
chr6_-_2971048 0.00 ENST00000612421.3
serpin family B member 6
chr12_+_64497968 0.00 ENST00000676593.1
ENST00000677093.1
TANK binding kinase 1
novel transcript
chr16_+_56191476 0.00 ENST00000262493.12
G protein subunit alpha o1
chr18_+_58341038 0.00 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr16_-_69351778 0.00 ENST00000288025.4
transmembrane p24 trafficking protein 6
chr6_-_116126120 0.00 ENST00000452729.1
ENST00000651968.1
ENST00000243222.8
collagen type X alpha 1 chain
chr1_-_153613095 0.00 ENST00000368706.9
S100 calcium binding protein A16
chr19_-_45730861 0.00 ENST00000317683.4
F-box protein 46

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.0 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0036029 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)