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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)
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Results for ZNF143
Z-value: 1.64
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Transcription factors associated with ZNF143
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF143 | hg38_v1_chr11_+_9461003_9461057 | -0.61 | 1.1e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF143
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.2 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.1 | 2.0 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.4 | 1.7 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 0.0 | 1.3 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 1.1 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.0 | 1.1 | GO:1901099 | negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240) |
| 0.3 | 1.0 | GO:0098935 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.2 | 1.0 | GO:1904566 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.2 | 1.0 | GO:0035624 | receptor transactivation(GO:0035624) |
| 0.2 | 1.0 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 2.2 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 2.0 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.0 | 1.9 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 1.6 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 1.2 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 1.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 1.1 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 1.0 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 1.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 1.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.4 | 1.7 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.0 | 1.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 1.1 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 1.0 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.1 | 1.0 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.9 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.1 | 0.8 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.1 | 0.8 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 2.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 1.8 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.1 | 1.7 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 1.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.1 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 1.1 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.0 | 0.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.6 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.0 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 2.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 1.7 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 1.3 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.1 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 1.0 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.7 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.7 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |