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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZNF350

Z-value: 0.49

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.7 zinc finger protein 350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg38_v1_chr19_-_51986670_51986859-0.601.1e-01Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_43935807 0.60 ENST00000438616.3
ARTN
artemin
chr11_-_11621991 0.40 ENST00000227756.5
GALNT18
polypeptide N-acetylgalactosaminyltransferase 18
chr2_-_70553638 0.32 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
TGFA
transforming growth factor alpha
chr14_+_96204679 0.31 ENST00000542454.2
ENST00000539359.1
ENST00000554311.2
ENST00000553811.1
BDKRB2
ENSG00000258691.1
bradykinin receptor B2
novel protein
chr11_-_112164080 0.27 ENST00000528832.1
ENST00000280357.12
IL18
interleukin 18
chr11_-_112164056 0.27 ENST00000524595.5
IL18
interleukin 18
chr1_+_109249530 0.25 ENST00000271332.4
CELSR2
cadherin EGF LAG seven-pass G-type receptor 2
chr5_-_16617085 0.23 ENST00000684521.1
RETREG1
reticulophagy regulator 1
chr2_-_70553440 0.21 ENST00000450929.5
TGFA
transforming growth factor alpha
chr5_-_16616972 0.20 ENST00000682564.1
ENST00000306320.10
ENST00000682229.1
RETREG1
reticulophagy regulator 1
chr12_+_112938523 0.18 ENST00000679483.1
ENST00000679493.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr11_+_33376077 0.18 ENST00000658780.2
KIAA1549L
KIAA1549 like
chr12_+_112938284 0.17 ENST00000681346.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr9_+_12693327 0.16 ENST00000388918.10
TYRP1
tyrosinase related protein 1
chr1_+_156150008 0.14 ENST00000355014.6
SEMA4A
semaphorin 4A
chr12_+_112938422 0.12 ENST00000680044.1
ENST00000680966.1
ENST00000548514.2
ENST00000681497.1
ENST00000551007.1
ENST00000228928.12
ENST00000680438.1
ENST00000681147.1
ENST00000679354.1
ENST00000681085.1
ENST00000680161.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr10_+_49614037 0.10 ENST00000395562.2
ENST00000337653.7
CHAT
choline O-acetyltransferase
chr4_+_119212636 0.10 ENST00000274030.10
USP53
ubiquitin specific peptidase 53
chr9_+_121567057 0.10 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr11_+_118956289 0.10 ENST00000264031.3
UPK2
uroplakin 2
chr1_-_200410001 0.09 ENST00000367353.2
ZNF281
zinc finger protein 281
chr11_-_9091546 0.09 ENST00000450649.6
SCUBE2
signal peptide, CUB domain and EGF like domain containing 2
chr4_-_25862979 0.09 ENST00000399878.8
SEL1L3
SEL1L family member 3
chr21_-_28992815 0.09 ENST00000361371.10
LTN1
listerin E3 ubiquitin protein ligase 1
chr6_-_40587314 0.09 ENST00000338305.7
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr1_-_246931892 0.09 ENST00000648844.2
AHCTF1
AT-hook containing transcription factor 1
chr2_-_9003657 0.08 ENST00000462696.1
ENST00000305997.8
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr11_-_75525925 0.08 ENST00000336898.8
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr20_+_19758245 0.08 ENST00000255006.12
RIN2
Ras and Rab interactor 2
chr21_-_28992947 0.07 ENST00000389194.7
ENST00000389195.7
ENST00000614971.4
LTN1
listerin E3 ubiquitin protein ligase 1
chr1_-_200410052 0.07 ENST00000294740.3
ZNF281
zinc finger protein 281
chr1_-_200409976 0.07 ENST00000367352.3
ZNF281
zinc finger protein 281
chr8_+_143213192 0.07 ENST00000622500.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr13_+_95677107 0.07 ENST00000602402.6
ENST00000376795.6
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3
chr12_-_47079926 0.07 ENST00000429635.1
ENST00000550413.2
AMIGO2
adhesion molecule with Ig like domain 2
chr17_-_76453142 0.07 ENST00000319380.12
UBE2O
ubiquitin conjugating enzyme E2 O
chr16_+_2429427 0.07 ENST00000397066.9
CCNF
cyclin F
chr12_+_47079586 0.06 ENST00000432328.2
ENST00000546455.6
PCED1B
PC-esterase domain containing 1B
chr12_-_47079859 0.06 ENST00000266581.4
AMIGO2
adhesion molecule with Ig like domain 2
chr1_-_204685353 0.06 ENST00000367176.7
LRRN2
leucine rich repeat neuronal 2
chr3_+_114056728 0.06 ENST00000485050.5
ENST00000281273.8
ENST00000479882.5
ENST00000493014.1
QTRT2
queuine tRNA-ribosyltransferase accessory subunit 2
chr11_+_706222 0.05 ENST00000318562.13
ENST00000533500.5
EPS8L2
EPS8 like 2
chr5_-_784691 0.05 ENST00000508859.8
ENST00000652055.1
ENST00000651083.1
ZDHHC11B
zinc finger DHHC-type containing 11B
chr20_+_4686320 0.05 ENST00000430350.2
PRNP
prion protein
chr13_-_99086611 0.05 ENST00000427887.2
DOCK9
dedicator of cytokinesis 9
chr11_+_706117 0.05 ENST00000533256.5
ENST00000614442.4
EPS8L2
EPS8 like 2
chr5_+_7396099 0.05 ENST00000338316.9
ADCY2
adenylate cyclase 2
chr17_+_19127535 0.05 ENST00000577213.1
ENST00000344415.9
GRAPL
GRB2 related adaptor protein like
chr20_+_4686448 0.05 ENST00000379440.9
ENST00000424424.2
ENST00000457586.2
PRNP
prion protein
chr12_-_92929236 0.05 ENST00000322349.13
EEA1
early endosome antigen 1
chr1_-_45623967 0.05 ENST00000445048.2
ENST00000421127.6
ENST00000528266.6
CCDC17
coiled-coil domain containing 17
chr11_+_706196 0.04 ENST00000534755.5
ENST00000650127.1
EPS8L2
EPS8 like 2
chr16_+_4476340 0.04 ENST00000458134.7
ENST00000619528.4
ENST00000619913.4
ENST00000219700.10
ENST00000570646.6
ENST00000575120.5
ENST00000572812.5
ENST00000574466.5
ENST00000576827.5
ENST00000570445.5
HMOX2
heme oxygenase 2
chr1_-_246931326 0.04 ENST00000366508.5
ENST00000326225.3
AHCTF1
AT-hook containing transcription factor 1
chr20_-_56005466 0.04 ENST00000064571.3
CBLN4
cerebellin 4 precursor
chr9_+_129665603 0.04 ENST00000372469.6
PRRX2
paired related homeobox 2
chr17_-_41440983 0.04 ENST00000246646.4
KRT38
keratin 38
chr19_-_48740573 0.04 ENST00000222145.9
RASIP1
Ras interacting protein 1
chr15_-_65185299 0.04 ENST00000300107.7
CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit X
chr1_+_63322558 0.04 ENST00000371116.4
FOXD3
forkhead box D3
chr3_-_129183874 0.04 ENST00000422453.7
ENST00000451728.6
ENST00000446936.6
ENST00000502976.5
ENST00000500450.6
ENST00000441626.6
ENST00000504813.5
ENST00000512338.1
CNBP
CCHC-type zinc finger nucleic acid binding protein
chr5_+_177087412 0.04 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr10_-_12042771 0.04 ENST00000357604.10
UPF2
UPF2 regulator of nonsense mediated mRNA decay
chr4_+_74933095 0.04 ENST00000513238.5
PARM1
prostate androgen-regulated mucin-like protein 1
chr11_-_61920267 0.04 ENST00000531922.2
ENST00000301773.9
RAB3IL1
RAB3A interacting protein like 1
chr2_-_218659592 0.04 ENST00000411696.7
ZNF142
zinc finger protein 142
chr11_-_9091589 0.04 ENST00000649792.2
ENST00000520467.5
ENST00000309263.7
SCUBE2
signal peptide, CUB domain and EGF like domain containing 2
chr2_-_218659468 0.04 ENST00000450560.1
ENST00000449707.5
ENST00000440934.2
ZNF142
zinc finger protein 142
chr17_+_70075215 0.03 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr17_+_70075317 0.03 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr11_-_535514 0.03 ENST00000451590.5
ENST00000311189.8
ENST00000417302.6
HRAS
HRas proto-oncogene, GTPase
chr12_+_55932028 0.03 ENST00000394147.5
ENST00000551156.5
ENST00000553783.5
ENST00000557080.5
ENST00000432422.7
ENST00000556001.5
DGKA
diacylglycerol kinase alpha
chr3_-_128493173 0.03 ENST00000498200.1
ENST00000341105.7
GATA2
GATA binding protein 2
chr15_+_42402375 0.03 ENST00000397200.8
ENST00000569827.5
CAPN3
calpain 3
chr2_+_237692144 0.03 ENST00000289175.10
ENST00000244815.9
LRRFIP1
LRR binding FLII interacting protein 1
chr3_+_50191604 0.03 ENST00000232461.8
ENST00000433068.5
GNAT1
G protein subunit alpha transducin 1
chr12_-_113135710 0.03 ENST00000446861.7
RASAL1
RAS protein activator like 1
chr10_-_15719885 0.03 ENST00000378076.4
ITGA8
integrin subunit alpha 8
chr12_+_81078035 0.03 ENST00000261206.7
ENST00000548058.6
ACSS3
acyl-CoA synthetase short chain family member 3
chr3_+_37861849 0.03 ENST00000273179.10
CTDSPL
CTD small phosphatase like
chr3_+_93980203 0.03 ENST00000679607.1
ENST00000679587.1
ARL13B
ADP ribosylation factor like GTPase 13B
chr22_+_39077264 0.03 ENST00000407997.4
APOBEC3G
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr17_-_41812586 0.03 ENST00000355468.7
ENST00000590496.1
P3H4
prolyl 3-hydroxylase family member 4 (inactive)
chr15_-_58933668 0.03 ENST00000380516.7
SLTM
SAFB like transcription modulator
chr15_-_42737054 0.03 ENST00000563260.1
ENST00000356231.4
CDAN1
codanin 1
chr11_+_64555956 0.02 ENST00000377581.7
SLC22A11
solute carrier family 22 member 11
chr3_+_37861926 0.02 ENST00000443503.6
CTDSPL
CTD small phosphatase like
chr21_+_34668986 0.02 ENST00000349499.3
CLIC6
chloride intracellular channel 6
chr5_-_93741587 0.02 ENST00000606183.4
POU5F2
POU domain class 5, transcription factor 2
chr1_+_156642108 0.02 ENST00000457777.6
ENST00000329117.10
ENST00000424639.5
BCAN
brevican
chr11_+_57763820 0.02 ENST00000674106.1
CTNND1
catenin delta 1
chr19_+_55339867 0.02 ENST00000255613.8
KMT5C
lysine methyltransferase 5C
chr17_-_44014946 0.02 ENST00000587529.1
ENST00000206380.8
TMEM101
transmembrane protein 101
chr2_+_237692290 0.02 ENST00000420665.5
ENST00000392000.4
LRRFIP1
LRR binding FLII interacting protein 1
chr1_+_228208054 0.02 ENST00000284548.16
ENST00000422127.5
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr19_+_2249317 0.02 ENST00000221496.5
AMH
anti-Mullerian hormone
chr3_+_93980130 0.02 ENST00000535334.5
ENST00000681380.1
ENST00000303097.11
ENST00000486562.2
ENST00000471138.5
ENST00000394222.8
ENST00000679872.1
ENST00000679404.1
ENST00000681655.1
ENST00000679657.1
ENST00000679666.1
ARL13B
ADP ribosylation factor like GTPase 13B
chr10_+_75431605 0.02 ENST00000611255.5
LRMDA
leucine rich melanocyte differentiation associated
chr14_+_73136418 0.02 ENST00000557356.5
ENST00000556864.5
ENST00000556533.5
ENST00000556951.5
ENST00000557293.5
ENST00000553719.5
ENST00000553599.5
ENST00000556011.5
ENST00000394157.7
ENST00000357710.8
ENST00000560005.6
ENST00000555254.5
ENST00000554131.5
ENST00000324501.10
ENST00000557037.5
PSEN1
presenilin 1
chr10_+_123154414 0.02 ENST00000368858.9
BUB3
BUB3 mitotic checkpoint protein
chr12_-_108826161 0.02 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr11_+_706595 0.02 ENST00000531348.5
ENST00000530636.5
EPS8L2
EPS8 like 2
chr2_+_167248638 0.02 ENST00000295237.10
XIRP2
xin actin binding repeat containing 2
chr19_+_1450113 0.02 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC2
APC regulator of WNT signaling pathway 2
chr9_-_136304084 0.01 ENST00000638797.2
ENST00000624277.3
CCDC187
coiled-coil domain containing 187
chr22_+_50600783 0.01 ENST00000329492.6
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr8_-_138497254 0.01 ENST00000395297.6
FAM135B
family with sequence similarity 135 member B
chrX_-_120956600 0.01 ENST00000434883.3
CT47A7
cancer/testis antigen family 47 member A7
chr1_-_168136707 0.01 ENST00000539777.5
GPR161
G protein-coupled receptor 161
chr4_-_173334249 0.01 ENST00000506267.1
ENST00000296503.10
HMGB2
high mobility group box 2
chr3_+_141228721 0.01 ENST00000505013.5
PXYLP1
2-phosphoxylose phosphatase 1
chr10_-_92243246 0.01 ENST00000412050.8
ENST00000614585.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr2_-_156342348 0.01 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr2_+_241702027 0.01 ENST00000313552.11
ENST00000406941.5
ING5
inhibitor of growth family member 5
chr8_-_99893135 0.01 ENST00000524245.5
COX6C
cytochrome c oxidase subunit 6C
chr19_-_14517425 0.01 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr16_+_71845958 0.01 ENST00000427980.7
ENST00000568581.5
ATXN1L
IST1
ataxin 1 like
IST1 factor associated with ESCRT-III
chr4_-_173334385 0.01 ENST00000446922.6
HMGB2
high mobility group box 2
chr16_+_67248966 0.01 ENST00000299798.16
SLC9A5
solute carrier family 9 member A5
chr1_+_19664859 0.01 ENST00000289753.2
HTR6
5-hydroxytryptamine receptor 6
chr11_+_68903849 0.01 ENST00000675615.1
ENST00000255078.8
IGHMBP2
immunoglobulin mu DNA binding protein 2
chr11_+_64555924 0.01 ENST00000301891.9
SLC22A11
solute carrier family 22 member 11
chr1_+_156642148 0.01 ENST00000361588.5
BCAN
brevican
chr19_+_5681000 0.00 ENST00000581893.5
ENST00000411793.6
ENST00000301382.8
ENST00000581773.5
ENST00000339423.7
ENST00000423665.6
ENST00000583928.5
ENST00000342970.6
ENST00000422535.6
ENST00000581521.5
HSD11B1L
hydroxysteroid 11-beta dehydrogenase 1 like
chr17_+_50547089 0.00 ENST00000619622.4
ENST00000356488.8
ENST00000006658.11
SPATA20
spermatogenesis associated 20
chr17_+_7583828 0.00 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr3_-_45842066 0.00 ENST00000445698.1
ENST00000296135.11
LZTFL1
leucine zipper transcription factor like 1
chr16_+_31214088 0.00 ENST00000613872.1
TRIM72
tripartite motif containing 72
chr10_+_123154364 0.00 ENST00000368859.6
ENST00000368865.9
BUB3
BUB3 mitotic checkpoint protein
chr19_+_5681140 0.00 ENST00000579559.1
ENST00000577222.5
HSD11B1L
RPL36
hydroxysteroid 11-beta dehydrogenase 1 like
ribosomal protein L36
chr2_+_202376301 0.00 ENST00000374580.10
BMPR2
bone morphogenetic protein receptor type 2
chrX_+_23783163 0.00 ENST00000379254.5
ENST00000379270.5
ENST00000683890.1
SAT1
ENSG00000288706.1
spermidine/spermine N1-acetyltransferase 1
novel protein
chr10_-_119178791 0.00 ENST00000298510.4
PRDX3
peroxiredoxin 3
chr9_-_95509241 0.00 ENST00000331920.11
PTCH1
patched 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.6 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.4 GO:0061709 reticulophagy(GO:0061709)
0.0 0.5 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network