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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZNF740_ZNF219

Z-value: 0.96

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Transcription factors associated with ZNF740_ZNF219

Gene Symbol Gene ID Gene Info
ZNF740
ENSG00000139651.11 zinc finger protein 740
ZNF219
ENSG00000165804.16 zinc finger protein 219

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF219hg38_v1_chr14_-_21094488_210945000.961.4e-04Click!
ZNF740hg38_v1_chr12_+_53180679_531807550.961.5e-04Click!

Activity profile of ZNF740_ZNF219 motif

Sorted Z-values of ZNF740_ZNF219 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_94641145 1.68 ENST00000433389.8
ENST00000358397.9
ESRP1
epithelial splicing regulatory protein 1
chr20_+_59604527 1.67 ENST00000371015.6
PHACTR3
phosphatase and actin regulator 3
chr8_+_94641074 1.65 ENST00000423620.6
ESRP1
epithelial splicing regulatory protein 1
chr8_+_94641199 1.64 ENST00000646773.1
ENST00000454170.7
ESRP1
epithelial splicing regulatory protein 1
chr11_-_64166102 0.80 ENST00000255681.7
ENST00000675777.1
MACROD1
mono-ADP ribosylhydrolase 1
chr17_+_7884783 0.74 ENST00000380358.9
CHD3
chromodomain helicase DNA binding protein 3
chr14_-_105168753 0.61 ENST00000331782.8
ENST00000347004.2
JAG2
jagged canonical Notch ligand 2
chr3_+_189789643 0.59 ENST00000354600.10
TP63
tumor protein p63
chr3_-_185825029 0.59 ENST00000382199.7
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr14_+_93430927 0.56 ENST00000393151.6
UNC79
unc-79 homolog, NALCN channel complex subunit
chr3_-_185824966 0.54 ENST00000457616.6
ENST00000346192.7
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr20_-_22584547 0.53 ENST00000419308.7
FOXA2
forkhead box A2
chr6_-_33317728 0.49 ENST00000431845.3
ZBTB22
zinc finger and BTB domain containing 22
chr6_-_32190170 0.48 ENST00000375050.6
PBX2
PBX homeobox 2
chr14_-_21526391 0.47 ENST00000611430.4
SALL2
spalt like transcription factor 2
chr14_-_21526312 0.40 ENST00000537235.2
SALL2
spalt like transcription factor 2
chr1_-_32964685 0.40 ENST00000373456.11
ENST00000356990.9
ENST00000235150.5
RNF19B
ring finger protein 19B
chr17_+_7439504 0.40 ENST00000575331.1
ENST00000293829.9
ENSG00000272884.1
FGF11
novel transcript
fibroblast growth factor 11
chr7_+_21428184 0.40 ENST00000649633.1
SP4
Sp4 transcription factor
chr17_+_57256727 0.37 ENST00000675656.1
MSI2
musashi RNA binding protein 2
chr12_+_57755060 0.37 ENST00000266643.6
MARCHF9
membrane associated ring-CH-type finger 9
chr19_+_45251363 0.35 ENST00000620044.4
MARK4
microtubule affinity regulating kinase 4
chr12_-_54391270 0.34 ENST00000352268.10
ENST00000549962.5
ENST00000338010.9
ENST00000550774.5
ZNF385A
zinc finger protein 385A
chr2_-_60550900 0.34 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr16_+_81444799 0.34 ENST00000537098.8
CMIP
c-Maf inducing protein
chr19_+_45251249 0.34 ENST00000262891.9
ENST00000300843.8
MARK4
microtubule affinity regulating kinase 4
chr12_-_53220377 0.34 ENST00000543726.1
RARG
retinoic acid receptor gamma
chr20_-_52191697 0.31 ENST00000361387.6
ZFP64
ZFP64 zinc finger protein
chr1_+_26529745 0.31 ENST00000374168.7
ENST00000374166.8
RPS6KA1
ribosomal protein S6 kinase A1
chr8_+_32548303 0.31 ENST00000650967.1
NRG1
neuregulin 1
chrX_-_129654946 0.31 ENST00000429967.3
APLN
apelin
chr9_-_23821275 0.30 ENST00000380110.8
ELAVL2
ELAV like RNA binding protein 2
chr6_-_106974721 0.30 ENST00000606017.2
ENST00000620405.1
CD24
CD24 molecule
chr3_+_189789734 0.29 ENST00000437221.5
ENST00000392463.6
ENST00000392461.7
ENST00000449992.5
ENST00000456148.1
TP63
tumor protein p63
chr11_+_64234569 0.28 ENST00000309422.7
ENST00000426086.3
VEGFB
vascular endothelial growth factor B
chr7_+_21428023 0.28 ENST00000432066.2
ENST00000222584.8
SP4
Sp4 transcription factor
chr17_-_41518878 0.28 ENST00000254043.8
KRT15
keratin 15
chr11_+_68312542 0.27 ENST00000294304.12
LRP5
LDL receptor related protein 5
chr8_-_22133356 0.27 ENST00000680789.1
HR
HR lysine demethylase and nuclear receptor corepressor
chr18_-_76495191 0.27 ENST00000443185.7
ZNF516
zinc finger protein 516
chr14_-_23183641 0.27 ENST00000469263.5
ENST00000525062.1
ENST00000316902.12
ENST00000524758.1
SLC7A8
solute carrier family 7 member 8
chrX_+_153687918 0.27 ENST00000253122.10
SLC6A8
solute carrier family 6 member 8
chr7_+_69598465 0.26 ENST00000342771.10
AUTS2
activator of transcription and developmental regulator AUTS2
chr9_-_122228845 0.26 ENST00000394319.8
ENST00000340587.7
LHX6
LIM homeobox 6
chr6_-_142945160 0.26 ENST00000367603.8
HIVEP2
HIVEP zinc finger 2
chr20_-_32483438 0.26 ENST00000359676.9
NOL4L
nucleolar protein 4 like
chr17_+_57256514 0.26 ENST00000284073.7
ENST00000674964.1
MSI2
musashi RNA binding protein 2
chr16_+_29806078 0.25 ENST00000545521.5
MAZ
MYC associated zinc finger protein
chr19_+_46602050 0.25 ENST00000599839.5
ENST00000596362.1
CALM3
calmodulin 3
chr6_-_142945028 0.25 ENST00000012134.7
HIVEP2
HIVEP zinc finger 2
chr6_+_149317530 0.25 ENST00000636456.1
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
chr8_+_32548210 0.25 ENST00000523079.5
ENST00000650919.1
NRG1
neuregulin 1
chr20_+_36573458 0.24 ENST00000373874.6
TGIF2
TGFB induced factor homeobox 2
chr19_+_33796268 0.24 ENST00000587559.5
ENST00000588637.5
KCTD15
potassium channel tetramerization domain containing 15
chr6_-_32192630 0.23 ENST00000375040.8
GPSM3
G protein signaling modulator 3
chr6_-_34696839 0.23 ENST00000374026.7
ILRUN
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr6_-_34696733 0.23 ENST00000374023.8
ILRUN
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr20_+_36573589 0.22 ENST00000373872.9
ENST00000650844.1
TGIF2
TGFB induced factor homeobox 2
chr3_-_171460368 0.21 ENST00000436636.7
ENST00000465393.1
ENST00000341852.10
TNIK
TRAF2 and NCK interacting kinase
chr6_+_149317695 0.21 ENST00000637181.2
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
chr6_-_32192845 0.21 ENST00000487761.5
GPSM3
G protein signaling modulator 3
chr16_+_74999312 0.20 ENST00000566250.5
ENST00000567962.5
ZNRF1
zinc and ring finger 1
chr13_-_40666600 0.20 ENST00000379561.6
FOXO1
forkhead box O1
chrX_+_71095838 0.20 ENST00000374259.8
FOXO4
forkhead box O4
chr19_-_43639788 0.20 ENST00000222374.3
CADM4
cell adhesion molecule 4
chr12_+_57522801 0.20 ENST00000355673.8
ENST00000546632.1
ENST00000549623.1
MBD6
methyl-CpG binding domain protein 6
chr12_-_57846686 0.20 ENST00000548823.1
ENST00000398073.7
CTDSP2
CTD small phosphatase 2
chr19_-_18542971 0.19 ENST00000596558.6
FKBP8
FKBP prolyl isomerase 8
chr17_+_59220446 0.19 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr19_-_18543556 0.19 ENST00000544835.7
ENST00000608443.6
ENST00000597960.7
FKBP8
FKBP prolyl isomerase 8
chr19_-_18543483 0.19 ENST00000597547.1
ENST00000222308.8
FKBP8
FKBP prolyl isomerase 8
chr12_-_54385727 0.19 ENST00000551109.5
ENST00000546970.5
ZNF385A
zinc finger protein 385A
chr19_-_48511793 0.19 ENST00000600059.6
LMTK3
lemur tyrosine kinase 3
chr10_-_101775974 0.18 ENST00000346714.7
ENST00000347978.2
FGF8
fibroblast growth factor 8
chr8_+_122781621 0.18 ENST00000314393.6
ZHX2
zinc fingers and homeoboxes 2
chr6_-_42451261 0.18 ENST00000372917.8
ENST00000340840.6
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr19_-_40716869 0.18 ENST00000677018.1
ENST00000324464.8
ENST00000594720.6
ENST00000677496.1
COQ8B
coenzyme Q8B
chr3_-_64687992 0.18 ENST00000498707.5
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr3_-_171460063 0.18 ENST00000284483.12
ENST00000475336.5
ENST00000357327.9
ENST00000460047.5
ENST00000488470.5
ENST00000470834.5
TNIK
TRAF2 and NCK interacting kinase
chr20_+_6767678 0.18 ENST00000378827.5
BMP2
bone morphogenetic protein 2
chr19_+_11346556 0.17 ENST00000587531.5
CCDC159
coiled-coil domain containing 159
chr13_+_46553157 0.17 ENST00000311191.10
ENST00000389797.8
ENST00000389798.7
LRCH1
leucine rich repeats and calponin homology domain containing 1
chr17_-_7404039 0.17 ENST00000576017.1
ENST00000302422.4
TMEM256
transmembrane protein 256
chr1_-_242524687 0.17 ENST00000442594.6
ENST00000536534.7
PLD5
phospholipase D family member 5
chr1_+_212285383 0.17 ENST00000261461.7
PPP2R5A
protein phosphatase 2 regulatory subunit B'alpha
chr1_-_18956669 0.17 ENST00000455833.7
IFFO2
intermediate filament family orphan 2
chr17_-_76537699 0.16 ENST00000293230.10
CYGB
cytoglobin
chr3_-_133895453 0.16 ENST00000486858.5
ENST00000477759.5
RAB6B
RAB6B, member RAS oncogene family
chr1_-_40665654 0.16 ENST00000372684.8
RIMS3
regulating synaptic membrane exocytosis 3
chr15_-_42920638 0.16 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
TTBK2
tau tubulin kinase 2
chr19_+_33796846 0.16 ENST00000590771.5
ENST00000589786.5
ENST00000284006.10
ENST00000683859.1
ENST00000588881.5
KCTD15
potassium channel tetramerization domain containing 15
chr17_-_44199834 0.15 ENST00000587097.6
ATXN7L3
ataxin 7 like 3
chr1_+_13584262 0.15 ENST00000376061.8
ENST00000513143.5
PDPN
podoplanin
chr20_-_32483507 0.15 ENST00000326071.8
NOL4L
nucleolar protein 4 like
chr1_+_65147830 0.15 ENST00000395334.6
AK4
adenylate kinase 4
chr2_+_180981108 0.15 ENST00000602710.5
UBE2E3
ubiquitin conjugating enzyme E2 E3
chr17_-_7217206 0.15 ENST00000447163.6
ENST00000647975.1
DLG4
discs large MAGUK scaffold protein 4
chr22_+_46150590 0.15 ENST00000262735.9
ENST00000420804.5
PPARA
peroxisome proliferator activated receptor alpha
chr14_+_95876385 0.15 ENST00000504119.1
TUNAR
TCL1 upstream neural differentiation-associated RNA
chrX_-_47650488 0.14 ENST00000247161.7
ENST00000376983.8
ENST00000343894.8
ELK1
ETS transcription factor ELK1
chr1_-_6261053 0.14 ENST00000377893.3
GPR153
G protein-coupled receptor 153
chr19_-_51646800 0.14 ENST00000599649.5
ENST00000429354.3
ENST00000360844.6
SIGLEC5
SIGLEC14
sialic acid binding Ig like lectin 5
sialic acid binding Ig like lectin 14
chr7_+_107168961 0.14 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HBP1
HMG-box transcription factor 1
chr12_-_6689359 0.14 ENST00000683879.1
ZNF384
zinc finger protein 384
chr18_-_26549402 0.14 ENST00000408011.7
KCTD1
potassium channel tetramerization domain containing 1
chr7_-_105691637 0.14 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr12_+_7189845 0.14 ENST00000412720.6
ENST00000396637.7
PEX5
peroxisomal biogenesis factor 5
chr3_-_142028597 0.14 ENST00000467667.5
TFDP2
transcription factor Dp-2
chr18_-_55588184 0.14 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
TCF4
transcription factor 4
chr3_+_51983438 0.14 ENST00000476351.5
ENST00000476854.5
ENST00000494103.5
ENST00000404366.7
ENST00000635797.1
ENST00000636358.2
ENST00000469863.1
ACY1
aminoacylase 1
chr1_+_95117324 0.14 ENST00000370203.9
ENST00000456991.5
TLCD4
TLC domain containing 4
chr3_-_18424533 0.14 ENST00000417717.6
SATB1
SATB homeobox 1
chr2_+_24049673 0.14 ENST00000380991.8
FKBP1B
FKBP prolyl isomerase 1B
chr10_+_119207560 0.13 ENST00000392870.3
GRK5
G protein-coupled receptor kinase 5
chr18_-_51197671 0.13 ENST00000406189.4
MEX3C
mex-3 RNA binding family member C
chr14_+_64704380 0.13 ENST00000247226.13
ENST00000394691.7
PLEKHG3
pleckstrin homology and RhoGEF domain containing G3
chr12_-_26125023 0.13 ENST00000242728.5
BHLHE41
basic helix-loop-helix family member e41
chr16_-_4614859 0.13 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
UBALD1
UBA like domain containing 1
chr1_-_37808168 0.13 ENST00000373044.3
YRDC
yrdC N6-threonylcarbamoyltransferase domain containing
chr7_+_151086466 0.13 ENST00000397238.7
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr6_+_27824084 0.13 ENST00000355057.3
H4C11
H4 clustered histone 11
chr7_+_20330893 0.13 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr16_+_29806519 0.13 ENST00000322945.11
ENST00000562337.5
ENST00000566906.6
ENST00000563402.1
ENST00000219782.10
MAZ
MYC associated zinc finger protein
chr2_+_219460719 0.13 ENST00000396688.5
SPEG
striated muscle enriched protein kinase
chr1_-_204152010 0.13 ENST00000367202.9
ETNK2
ethanolamine kinase 2
chr1_+_13583762 0.13 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
PDPN
podoplanin
chr12_-_53220229 0.13 ENST00000338561.9
RARG
retinoic acid receptor gamma
chr14_+_95876762 0.13 ENST00000503525.2
TUNAR
TCL1 upstream neural differentiation-associated RNA
chr1_-_243850070 0.13 ENST00000366539.6
ENST00000672578.1
AKT3
AKT serine/threonine kinase 3
chr4_+_145482761 0.13 ENST00000507367.1
ENST00000394092.6
ENST00000515385.1
SMAD1
SMAD family member 1
chr3_+_194136138 0.13 ENST00000232424.4
HES1
hes family bHLH transcription factor 1
chr9_+_33817126 0.13 ENST00000263228.4
UBE2R2
ubiquitin conjugating enzyme E2 R2
chr17_+_56593685 0.12 ENST00000332822.6
NOG
noggin
chr8_+_123416735 0.12 ENST00000524254.5
NTAQ1
N-terminal glutamine amidase 1
chr17_-_7251691 0.12 ENST00000574322.6
CTDNEP1
CTD nuclear envelope phosphatase 1
chrX_+_77447387 0.12 ENST00000439435.3
FGF16
fibroblast growth factor 16
chr15_-_42920798 0.12 ENST00000622375.4
ENST00000567840.5
TTBK2
tau tubulin kinase 2
chr14_-_77141777 0.12 ENST00000319374.4
ZDHHC22
zinc finger DHHC-type palmitoyltransferase 22
chr18_+_58862904 0.12 ENST00000591083.5
ZNF532
zinc finger protein 532
chr12_-_6689244 0.12 ENST00000361959.7
ENST00000436774.6
ENST00000544482.1
ZNF384
zinc finger protein 384
chr1_-_204151884 0.12 ENST00000367201.7
ETNK2
ethanolamine kinase 2
chr6_-_42451910 0.12 ENST00000372922.8
ENST00000541110.5
TRERF1
transcriptional regulating factor 1
chr22_-_39244969 0.12 ENST00000331163.11
PDGFB
platelet derived growth factor subunit B
chr10_-_118754956 0.12 ENST00000369151.8
CACUL1
CDK2 associated cullin domain 1
chr2_+_24049705 0.12 ENST00000380986.9
ENST00000452109.1
FKBP1B
FKBP prolyl isomerase 1B
chr16_+_67029359 0.12 ENST00000565389.1
CBFB
core-binding factor subunit beta
chr3_+_50155305 0.12 ENST00000002829.8
ENST00000426511.5
SEMA3F
semaphorin 3F
chr1_+_167936818 0.12 ENST00000367840.3
DCAF6
DDB1 and CUL4 associated factor 6
chr10_-_84241538 0.12 ENST00000372105.4
LRIT1
leucine rich repeat, Ig-like and transmembrane domains 1
chr19_-_45973863 0.12 ENST00000263257.6
NOVA2
NOVA alternative splicing regulator 2
chr1_+_161159450 0.12 ENST00000492950.5
ENST00000289865.12
ENST00000368002.8
ENST00000479344.1
ENST00000368001.1
USP21
ubiquitin specific peptidase 21
chr17_+_35809474 0.12 ENST00000604879.5
ENST00000603427.5
ENST00000603777.5
ENST00000605844.6
ENST00000604841.5
TAF15
TATA-box binding protein associated factor 15
chr10_+_97572771 0.12 ENST00000370655.6
ENST00000455090.1
ANKRD2
ankyrin repeat domain 2
chr8_+_123416718 0.12 ENST00000523984.5
NTAQ1
N-terminal glutamine amidase 1
chr12_+_51239278 0.11 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr17_-_44199206 0.11 ENST00000589805.1
ATXN7L3
ataxin 7 like 3
chr2_+_28751802 0.11 ENST00000296122.10
ENST00000395366.3
PPP1CB
protein phosphatase 1 catalytic subunit beta
chr10_-_101776104 0.11 ENST00000320185.7
ENST00000344255.8
FGF8
fibroblast growth factor 8
chr3_+_50155024 0.11 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
SEMA3F
semaphorin 3F
chr15_-_88256158 0.11 ENST00000317501.7
ENST00000629765.2
ENST00000557856.5
ENST00000558676.5
NTRK3
neurotrophic receptor tyrosine kinase 3
chr17_-_29589606 0.11 ENST00000225394.8
GIT1
GIT ArfGAP 1
chr16_+_11668414 0.11 ENST00000329565.6
SNN
stannin
chrX_+_136148440 0.11 ENST00000627383.2
ENST00000630084.2
FHL1
four and a half LIM domains 1
chr19_-_14090695 0.11 ENST00000533683.7
SAMD1
sterile alpha motif domain containing 1
chr6_-_170291053 0.11 ENST00000366756.4
DLL1
delta like canonical Notch ligand 1
chr11_-_123654581 0.11 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
SCN3B
sodium voltage-gated channel beta subunit 3
chr5_-_95961830 0.11 ENST00000513343.1
ENST00000237853.9
ELL2
elongation factor for RNA polymerase II 2
chr16_+_3024000 0.11 ENST00000326266.13
ENST00000574549.5
ENST00000575576.5
ENST00000253952.9
THOC6
THO complex 6
chr16_-_3024230 0.11 ENST00000572355.5
ENST00000574980.5
ENST00000354679.3
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1
chrX_-_48971829 0.11 ENST00000218176.4
KCND1
potassium voltage-gated channel subfamily D member 1
chr6_+_18155399 0.11 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
KDM1B
lysine demethylase 1B
chr2_-_148021490 0.11 ENST00000416719.5
ENST00000264169.6
ORC4
origin recognition complex subunit 4
chr18_+_3449817 0.11 ENST00000407501.6
TGIF1
TGFB induced factor homeobox 1
chr17_-_65056659 0.10 ENST00000439174.7
GNA13
G protein subunit alpha 13
chr14_+_93430853 0.10 ENST00000553484.5
UNC79
unc-79 homolog, NALCN channel complex subunit
chr8_+_123416766 0.10 ENST00000287387.7
ENST00000650311.1
ENST00000523356.1
NTAQ1
N-terminal glutamine amidase 1
chr17_+_82032182 0.10 ENST00000584341.1
RAC3
Rac family small GTPase 3
chr12_+_7189675 0.10 ENST00000675855.1
ENST00000434354.6
ENST00000544456.5
ENST00000545574.5
ENST00000420616.6
PEX5
peroxisomal biogenesis factor 5
chr18_+_79964629 0.10 ENST00000451882.3
HSBP1L1
heat shock factor binding protein 1 like 1
chr15_-_45187955 0.10 ENST00000560471.5
ENST00000560540.5
SHF
Src homology 2 domain containing F
chr7_-_151814636 0.10 ENST00000652047.1
ENST00000650858.1
PRKAG2
protein kinase AMP-activated non-catalytic subunit gamma 2
chr17_+_82032061 0.10 ENST00000580965.5
RAC3
Rac family small GTPase 3
chr14_-_22982544 0.10 ENST00000262713.7
AJUBA
ajuba LIM protein
chr17_-_76537630 0.10 ENST00000589342.1
CYGB
cytoglobin
chr12_-_57520480 0.10 ENST00000642841.1
ENST00000547303.5
ENST00000552740.5
ENST00000547526.1
ENST00000346473.8
ENST00000551116.5
ENSG00000285133.1
DDIT3
novel protein
DNA damage inducible transcript 3
chr9_-_37465402 0.10 ENST00000307750.5
ZBTB5
zinc finger and BTB domain containing 5
chr19_-_17245889 0.10 ENST00000291442.4
NR2F6
nuclear receptor subfamily 2 group F member 6
chr8_+_26383043 0.10 ENST00000380629.7
BNIP3L
BCL2 interacting protein 3 like
chr6_+_42782020 0.10 ENST00000314073.9
BICRAL
BRD4 interacting chromatin remodeling complex associated protein like
chr16_+_67029093 0.10 ENST00000561924.6
CBFB
core-binding factor subunit beta
chr7_+_26201705 0.10 ENST00000396386.7
ENST00000456948.5
ENST00000409747.5
CBX3
chromobox 3
chr12_-_6689450 0.10 ENST00000355772.8
ENST00000417772.7
ENST00000319770.7
ENST00000396801.7
ZNF384
zinc finger protein 384
chr14_-_21094488 0.10 ENST00000555270.5
ZNF219
zinc finger protein 219
chr1_-_156500723 0.10 ENST00000368240.6
MEF2D
myocyte enhancer factor 2D
chr1_-_156500763 0.10 ENST00000348159.9
ENST00000489057.1
MEF2D
myocyte enhancer factor 2D
chr19_-_45973986 0.10 ENST00000676183.1
NOVA2
NOVA alternative splicing regulator 2
chr17_+_45161070 0.10 ENST00000593138.6
ENST00000586681.6
HEXIM2
HEXIM P-TEFb complex subunit 2
chr6_+_33428223 0.09 ENST00000682587.1
SYNGAP1
synaptic Ras GTPase activating protein 1
chr15_-_45187947 0.09 ENST00000560734.5
SHF
Src homology 2 domain containing F
chr19_-_41397256 0.09 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.9
EXOSC5
exosome component 5

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF740_ZNF219

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 0.5 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 0.5 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.5 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.3 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.3 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.2 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 0.3 GO:0032599 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.1 0.7 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.2 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.2 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.2 GO:1902617 response to fluoride(GO:1902617)
0.0 0.2 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:2000489 regulation of hepatic stellate cell activation(GO:2000489)
0.0 0.7 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.5 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.2 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 5.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:2000798 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.0 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.0 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.5 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.0 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.0 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.8 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 5.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0051184 cofactor transporter activity(GO:0051184)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.0 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation