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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZNF8

Z-value: 0.61

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Transcription factors associated with ZNF8

Gene Symbol Gene ID Gene Info
ENSG00000278129.2 zinc finger protein 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF8hg38_v1_chr19_+_58278948_58278992-0.743.5e-02Click!

Activity profile of ZNF8 motif

Sorted Z-values of ZNF8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_35248994 0.63 ENST00000427250.5
ENST00000605618.6
lipolysis stimulated lipoprotein receptor
chr19_+_35248879 0.60 ENST00000347609.8
lipolysis stimulated lipoprotein receptor
chr3_-_57079287 0.48 ENST00000338458.8
ENST00000468727.5
Rho guanine nucleotide exchange factor 3
chr19_-_55140922 0.39 ENST00000589745.5
troponin T1, slow skeletal type
chr1_-_54801290 0.23 ENST00000371276.9
tetratricopeptide repeat domain 22
chr6_+_18155399 0.17 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
lysine demethylase 1B
chrX_+_129779930 0.15 ENST00000356892.4
SAM and SH3 domain containing 3
chr17_+_50508384 0.12 ENST00000436259.6
ENST00000652471.1
ENST00000323776.11
ENST00000419930.2
MYCBP associated protein
chr6_+_29723340 0.10 ENST00000334668.8
major histocompatibility complex, class I, F
chr7_+_48035511 0.09 ENST00000420324.5
ENST00000539619.5
ENST00000435376.5
ENST00000430738.5
ENST00000348904.4
chromosome 7 open reading frame 57
chr12_-_46268989 0.09 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
solute carrier family 38 member 1
chr6_+_29723421 0.09 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr2_-_171433950 0.08 ENST00000375258.9
ENST00000442541.1
ENST00000392599.6
methyltransferase like 8
chr1_-_235128819 0.07 ENST00000366607.5
translocase of outer mitochondrial membrane 20
chr11_+_13668653 0.06 ENST00000354817.8
fatty acyl-CoA reductase 1
chr9_+_32552305 0.06 ENST00000451672.2
ENST00000644531.1
small integral membrane protein 27
chr8_-_108248700 0.06 ENST00000220849.10
ENST00000678937.1
ENST00000678901.1
ENST00000678243.1
ENST00000677674.1
ENST00000521297.2
ENST00000677272.1
ENST00000522352.6
ENST00000678042.1
ENST00000519627.2
ENST00000521440.6
ENST00000678773.1
ENST00000676698.1
ENST00000518345.2
ENST00000677447.1
ENST00000676548.1
ENST00000519030.6
ENST00000518442.5
eukaryotic translation initiation factor 3 subunit E
chr11_+_13668702 0.06 ENST00000532701.1
fatty acyl-CoA reductase 1
chr6_+_116280098 0.05 ENST00000643175.1
ENST00000452085.7
dermatan sulfate epimerase
chr6_-_107459504 0.05 ENST00000369037.9
ENST00000369031.4
decaprenyl diphosphate synthase subunit 2
chr2_+_119431846 0.05 ENST00000306406.5
transmembrane protein 37
chr2_+_197500371 0.04 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr9_-_32552553 0.04 ENST00000379858.1
ENST00000360538.7
ENST00000681750.1
ENST00000680198.1
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
novel protein
chr1_-_54801161 0.04 ENST00000371274.8
tetratricopeptide repeat domain 22
chr17_+_35809474 0.04 ENST00000604879.5
ENST00000603427.5
ENST00000603777.5
ENST00000605844.6
ENST00000604841.5
TATA-box binding protein associated factor 15
chr13_+_36819214 0.03 ENST00000255476.3
regulatory factor X associated protein
chr15_+_84980440 0.03 ENST00000310298.8
ENST00000557957.5
phosphodiesterase 8A
chr6_+_87407965 0.03 ENST00000369562.9
cilia and flagella associated protein 206
chr1_-_100249815 0.03 ENST00000370131.3
ENST00000681617.1
ENST00000681780.1
ENST00000370132.8
dihydrolipoamide branched chain transacylase E2
chr7_+_118184105 0.03 ENST00000424702.1
LSM8 homolog, U6 small nuclear RNA associated
chr6_+_44246166 0.02 ENST00000620073.4
heat shock protein 90 alpha family class B member 1
chr4_+_185426234 0.02 ENST00000511138.5
ENST00000511581.5
ENST00000378850.5
chromosome 4 open reading frame 47
chr7_+_100706061 0.02 ENST00000303151.5
POP7 homolog, ribonuclease P/MRP subunit
chr16_+_21953341 0.02 ENST00000268379.9
ENST00000561553.5
ENST00000565331.5
ubiquinol-cytochrome c reductase core protein 2
chr6_-_26056460 0.02 ENST00000343677.4
H1.2 linker histone, cluster member
chr10_+_988425 0.02 ENST00000360803.9
GTP binding protein 4
chr13_+_52455429 0.02 ENST00000468284.1
ENST00000378034.7
ENST00000378037.9
ENST00000258607.10
cytoskeleton associated protein 2
chr3_+_113838772 0.02 ENST00000358160.9
GRAM domain containing 1C
chr6_-_116279837 0.01 ENST00000368608.4
TSPY like 1
chr2_-_105329685 0.01 ENST00000393359.7
transforming growth factor beta receptor associated protein 1
chr7_+_45574358 0.01 ENST00000297323.12
adenylate cyclase 1
chr1_+_25338294 0.01 ENST00000374358.5
transmembrane protein 50A
chr7_+_1709162 0.01 ENST00000561626.3
extracellular leucine rich repeat and fibronectin type III domain containing 1
chr13_-_21176540 0.01 ENST00000400018.7
ENST00000314759.6
spindle and kinetochore associated complex subunit 3
chr7_-_75073844 0.01 ENST00000614461.4
ENST00000618035.4
RCC1 like
chr9_+_32551670 0.01 ENST00000450093.3
small integral membrane protein 27
chrX_+_130401962 0.01 ENST00000305536.11
ENST00000370947.1
RNA binding motif protein X-linked 2
chr9_+_93263948 0.01 ENST00000448251.5
WNK lysine deficient protein kinase 2
chr2_+_189441460 0.01 ENST00000314761.9
ENST00000631047.1
WD repeat domain 75
chr2_+_171434196 0.00 ENST00000375255.8
ENST00000539783.5
DDB1 and CUL4 associated factor 17
chr12_-_122266410 0.00 ENST00000451053.3
VPS33A core subunit of CORVET and HOPS complexes
chr8_+_26291758 0.00 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr4_-_76148382 0.00 ENST00000264883.8
ENST00000514987.5
ENST00000514901.5
nucleoporin 54
chr17_-_28842727 0.00 ENST00000583307.6
ENST00000581229.6
ENST00000582266.6
ENST00000577376.6
ENST00000577682.6
ENST00000581407.6
ENST00000341217.7
ENST00000583522.6
family with sequence similarity 222 member B
chr2_-_239400949 0.00 ENST00000345617.7
histone deacetylase 4
chr12_+_52069967 0.00 ENST00000336854.9
ENST00000550604.1
ENST00000553049.5
ENST00000548915.1
autophagy related 101

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway