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GSE43616: Time-course of wild-type Arabidopsis leaf

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Results for AT1G14350

Z-value: 0.38

Transcription factors associated with AT1G14350

Gene Symbol Gene ID Gene Info
AT1G14350
AT1G14350 Duplicated homeodomain-like superfamily protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FLParTal_v1_Chr1_+_4907887_4907917-0.212.9e-01Click!

Activity profile of AT1G14350 motif

Sorted Z-values of AT1G14350 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
arTal_v1_Chr1_-_19336072_19336135 0.99 AT1G52000.2
AT1G52000.1
AT1G52000
Mannose-binding lectin superfamily protein
arTal_v1_Chr2_-_1800472_1800472 0.72 AT2G05070.1
LHCB2.2
photosystem II light harvesting complex protein 2.2
arTal_v1_Chr3_-_8229619_8229619 0.59 AT3G23120.1
RLP38
receptor like protein 38
arTal_v1_Chr3_+_22373013_22373013 0.52 AT3G60530.1
GATA4
GATA transcription factor 4
arTal_v1_Chr4_-_7992429_7992429 0.51 AT4G13770.1
CYP83A1
cytochrome P450, family 83, subfamily A, polypeptide 1
arTal_v1_Chr4_-_7153571_7153681 0.51 AT4G11900.10
AT4G11900.8
AT4G11900.9
AT4G11900.7
AT4G11900.6
AT4G11900.3
AT4G11900.5
AT4G11900.2
AT4G11900.4
AT4G11900.1
AT4G11900
S-locus lectin protein kinase family protein
arTal_v1_Chr1_-_498539_498539 0.46 AT1G02450.1
NIMIN1
NIM1-interacting 1
arTal_v1_Chr2_+_14783254_14783254 0.42 AT2G35070.1
AT2G35070.2
AT2G35070
transmembrane protein
arTal_v1_Chr2_+_6947096_6947096 0.38 AT2G15960.1
AT2G15960
stress-induced protein
arTal_v1_Chr3_+_9769634_9769666 0.35 AT3G26600.2
AT3G26600.1
ARO4
armadillo repeat only 4
arTal_v1_Chr5_-_22230500_22230500 0.34 AT5G54710.1
AT5G54710
Ankyrin repeat family protein
arTal_v1_Chr1_+_2238017_2238154 0.33 AT1G07280.1
AT1G07280.2
AT1G07280.4
AT1G07280.3
AT1G07280
Tetratricopeptide repeat (TPR)-like superfamily protein
arTal_v1_Chr5_-_22230663_22230663 0.33 AT5G54710.2
AT5G54710
Ankyrin repeat family protein
arTal_v1_Chr1_+_21746354_21746373 0.33 AT1G58602.2
AT1G58602.1
AT1G58602
LRR and NB-ARC domains-containing disease resistance protein
arTal_v1_Chr5_-_15859911_15859911 0.33 AT5G39610.1
NAC6
NAC domain containing protein 6
arTal_v1_Chr4_-_1230164_1230164 0.30 AT4G02770.1
PSAD-1
photosystem I subunit D-1
arTal_v1_Chr1_+_20112141_20112149 0.28 AT1G53870.2
AT1G53870.1
AT1G53870.3
AT1G53870.4
AT1G53870
LURP-one-like protein (DUF567)
arTal_v1_Chr1_-_17898804_17898813 0.26 AT1G48420.3
AT1G48420.2
AT1G48420.1
D-CDES
D-cysteine desulfhydrase
arTal_v1_Chr1_-_3590928_3590928 0.26 AT1G10760.1
AT1G10760.3
SEX1
Pyruvate phosphate dikinase, PEP/pyruvate binding domain-containing protein
arTal_v1_Chr1_-_3590701_3590701 0.25 AT1G10760.2
SEX1
Pyruvate phosphate dikinase, PEP/pyruvate binding domain-containing protein
arTal_v1_Chr4_-_367274_367274 0.23 AT4G00880.1
AT4G00880
SAUR-like auxin-responsive protein family
arTal_v1_Chr1_-_17706460_17706460 0.23 AT1G48000.1
MYB112
myb domain protein 112
arTal_v1_Chr3_-_9765570_9765570 0.21 AT3G26590.1
AT3G26590
MATE efflux family protein
arTal_v1_Chr3_-_10047453_10047453 0.20 AT3G27210.1
AT3G27210
hypothetical protein
arTal_v1_Chr1_+_12366810_12366831 0.20 AT1G34020.2
AT1G34020.1
AT1G34020.3
AT1G34020
Nucleotide-sugar transporter family protein
arTal_v1_Chr2_+_18498909_18499053 0.19 AT2G44850.2
AT2G44850.3
AT2G44850
hypothetical protein
arTal_v1_Chr2_+_15568926_15568986 0.19 AT2G37050.4
AT2G37050.3
AT2G37050.1
AT2G37050.2
AT2G37050
Leucine-rich repeat protein kinase family protein
arTal_v1_Chr3_+_18071454_18071454 0.18 AT3G48750.1
CDC2
cell division control 2
arTal_v1_Chr1_+_4788463_4788550 0.18 AT1G13980.2
AT1G13980.1
GN
sec7 domain-containing protein
arTal_v1_Chr5_-_15385247_15385320 0.18 AT5G38430.2
AT5G38430.1
RBCS1B
Ribulose bisphosphate carboxylase (small chain) family protein
arTal_v1_Chr5_-_6072334_6072334 0.17 AT5G18340.1
AT5G18340
ARM repeat superfamily protein
arTal_v1_Chr3_-_9764614_9764614 0.17 AT3G26590.2
AT3G26590
MATE efflux family protein
arTal_v1_Chr1_-_20979395_20979448 0.16 AT1G56090.1
AT1G56090.2
AT1G56090
Tetratricopeptide repeat (TPR)-like superfamily protein
arTal_v1_Chr5_-_2070378_2070378 0.16 AT5G06710.3
AT5G06710.4
HAT14
homeobox leucine zipper protein
arTal_v1_Chr5_-_2070566_2070566 0.15 AT5G06710.1
AT5G06710.2
HAT14
homeobox leucine zipper protein
arTal_v1_Chr5_+_3253122_3253122 0.15 AT5G10340.1
AT5G10340
F-box family protein
arTal_v1_Chr1_-_19851435_19851435 0.15 AT1G53230.2
TCP3
TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3
arTal_v1_Chr5_+_8354637_8354637 0.15 AT5G24460.1
AT5G24460
RING-H2 zinc finger protein
arTal_v1_Chr1_+_10654800_10654857 0.15 AT1G30270.1
AT1G30270.2
AT1G30270.3
CIPK23
CBL-interacting protein kinase 23
arTal_v1_Chr2_+_18661460_18661464 0.15 AT2G45250.1
AT2G45250.3
AT2G45250.2
AT2G45250
integral membrane hemolysin-III-like protein
arTal_v1_Chr1_-_3823088_3823088 0.14 AT1G11360.4
AT1G11360.1
AT1G11360.3
AT1G11360.2
AT1G11360
Adenine nucleotide alpha hydrolases-like superfamily protein
arTal_v1_Chr5_+_25181296_25181296 0.14 AT5G62690.1
TUB2
tubulin beta chain 2
arTal_v1_Chr1_+_21732566_21732636 0.14 AT1G58520.2
AT1G58520.4
AT1G58520.5
AT1G58520.1
AT1G58520.6
RXW8
GDSL-like lipase/acylhydrolase superfamily protein
arTal_v1_Chr1_-_19851725_19851725 0.14 AT1G53230.1
TCP3
TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3
arTal_v1_Chr3_+_20870000_20870000 0.14 AT3G56270.1
AT3G56270
WEB family protein (DUF827)
arTal_v1_Chr1_+_5702153_5702153 0.13 AT1G16680.1
AT1G16680
Chaperone DnaJ-domain superfamily protein
arTal_v1_Chr2_+_505375_505375 0.13 AT2G02070.1
AT2G02070.2
IDD5
indeterminate(ID)-domain 5
arTal_v1_Chr2_+_18498672_18498672 0.12 AT2G44850.1
AT2G44850
hypothetical protein
arTal_v1_Chr4_+_8195881_8195881 0.12 AT4G14220.1
RHF1A
RING-H2 group F1A
arTal_v1_Chr3_-_4824913_4824913 0.12 AT3G14430.1
AT3G14430
GRIP/coiled-coil protein
arTal_v1_Chr1_+_7963813_7963813 0.12 AT1G22540.1
AT1G22540
Major facilitator superfamily protein
arTal_v1_Chr4_-_18563981_18563987 0.12 AT4G40050.2
AT4G40050.1
AT4G40050
signal transducer, putative (DUF3550/UPF0682)
arTal_v1_Chr4_+_12714624_12714624 0.10 AT4G24630.1
AT4G24630
DHHC-type zinc finger family protein
arTal_v1_Chr1_+_21733493_21733493 0.10 AT1G58520.7
RXW8
GDSL-like lipase/acylhydrolase superfamily protein
arTal_v1_Chr1_-_12566615_12566615 0.10 AT1G34400.1
AT1G34400
hypothetical protein
arTal_v1_Chr3_+_20671115_20671115 0.09 AT3G55700.1
AT3G55700
UDP-Glycosyltransferase superfamily protein
arTal_v1_Chr2_-_12978868_12978949 0.09 AT2G30460.4
AT2G30460.3
AT2G30460.5
AT2G30460.2
AT2G30460.1
AT2G30460
Nucleotide/sugar transporter family protein
arTal_v1_Chr5_-_7152876_7152922 0.08 AT5G21060.3
AT5G21060.2
AT5G21060.1
AT5G21060
Glyceraldehyde-3-phosphate dehydrogenase-like family protein
arTal_v1_Chr1_+_6744353_6744405 0.08 AT1G19480.1
AT1G19480.2
AT1G19480
DNA glycosylase superfamily protein
arTal_v1_Chr2_+_567873_567873 0.08 AT2G02190.1
AT2G02190

arTal_v1_Chr1_-_24026209_24026209 0.07 AT1G64650.2
AT1G64650
Major facilitator superfamily protein
arTal_v1_Chr1_+_22208089_22208089 0.07 AT1G60220.1
ULP1D
UB-like protease 1D
arTal_v1_Chr3_+_10576961_10576961 0.07 AT3G28310.1
AT3G28310
hypothetical protein (DUF677)
arTal_v1_Chr1_-_24026530_24026530 0.06 AT1G64650.1
AT1G64650
Major facilitator superfamily protein
arTal_v1_Chr3_+_16569051_16569051 0.06 AT3G45230.1
AT3G45230
hydroxyproline-rich glycoprotein family protein
arTal_v1_Chr1_-_30249305_30249337 0.06 AT1G80460.2
AT1G80460.1
NHO1
Actin-like ATPase superfamily protein
arTal_v1_Chr1_+_11391199_11391199 0.06 AT1G31780.1
AT1G31780
oligomeric golgi complex subunit
arTal_v1_Chr5_-_15575712_15575712 0.05 AT5G38900.1
AT5G38900
Thioredoxin superfamily protein
arTal_v1_Chr3_+_20958563_20958584 0.05 AT3G56570.1
AT3G56570.2
AT3G56570
SET domain-containing protein
arTal_v1_Chr1_-_9864779_9864779 0.05 AT1G28230.1
PUP1
purine permease 1
arTal_v1_Chr2_-_12978194_12978194 0.05 AT2G30460.6
AT2G30460
Nucleotide/sugar transporter family protein
arTal_v1_Chr3_+_16421045_16421045 0.05 AT3G44950.1
AT3G44950
glycine-rich protein
arTal_v1_Chr5_-_15575437_15575437 0.05 AT5G38900.2
AT5G38900
Thioredoxin superfamily protein
arTal_v1_Chr3_-_20785885_20785885 0.05 AT3G56000.1
CSLA14
cellulose synthase like A14
arTal_v1_Chr5_+_9189425_9189440 0.04 AT5G26240.1
AT5G26240.2
CLC-D
chloride channel D
arTal_v1_Chr3_-_11086003_11086003 0.04 AT3G29110.1
AT3G29110
Terpenoid cyclases/Protein prenyltransferases superfamily protein
arTal_v1_Chr1_+_22192758_22192758 0.04 AT1G60170.1
emb1220
pre-mRNA processing ribonucleoprotein binding region-containing protein
arTal_v1_Chr2_+_13508493_13508493 0.04 AT2G31760.1
ARI10
RING/U-box superfamily protein
arTal_v1_Chr1_-_6155796_6155804 0.04 AT1G17890.2
AT1G17890.1
AT1G17890.3
GER2
NAD(P)-binding Rossmann-fold superfamily protein
arTal_v1_Chr2_+_16627216_16627216 0.04 AT2G39840.1
TOPP4
type one serine/threonine protein phosphatase 4
arTal_v1_Chr2_+_1798155_1798155 0.04 AT2G05060.1
AT2G05060
Protein kinase superfamily protein
arTal_v1_Chr4_+_5295756_5295756 0.04 AT4G08360.1
AT4G08360
KOW domain-containing protein
arTal_v1_Chr1_+_23121_23121 0.03 AT1G01040.1
DCL1
dicer-like 1
arTal_v1_Chr5_+_17409524_17409524 0.03 AT5G43360.1
PHT1%3B3
phosphate transporter 1;3
arTal_v1_Chr1_+_23416_23416 0.03 AT1G01040.2
DCL1
dicer-like 1
arTal_v1_Chr1_-_21334727_21334790 0.03 AT1G57600.1
AT1G57600.2
AT1G57600.3
AT1G57600
MBOAT (membrane bound O-acyl transferase) family protein
arTal_v1_Chr1_+_16999446_16999446 0.03 AT1G44960.1
AT1G44960
SNARE associated Golgi protein family
arTal_v1_Chr1_+_12426700_12426778 0.03 AT1G34120.1
AT1G34120.4
AT1G34120.2
AT1G34120.3
IP5PI
inositol polyphosphate 5-phosphatase I
arTal_v1_Chr1_-_11406809_11406809 0.03 AT1G31810.1
AFH14
Formin Homology 14
arTal_v1_Chr4_-_16862420_16862420 0.03 AT4G35510.1
AT4G35510
PHD finger-like protein
arTal_v1_Chr3_+_8014809_8014809 0.02 AT3G22650.1
AT3G22650.2
CEG
F-box and associated interaction domains-containing protein
arTal_v1_Chr2_+_9315204_9315204 0.02 AT2G21850.1
AT2G21850
Cysteine/Histidine-rich C1 domain family protein
arTal_v1_Chr4_+_7105136_7105136 0.02 AT4G11810.3
AT4G11810
Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein
arTal_v1_Chr5_+_9596766_9596766 0.02 AT5G27240.1
AT5G27240
DNAJ heat shock N-terminal domain-containing protein
arTal_v1_Chr2_+_12689581_12689581 0.02 AT2G29680.1
CDC6
cell division control 6
arTal_v1_Chr1_-_21334018_21334018 0.02 AT1G57600.4
AT1G57600
MBOAT (membrane bound O-acyl transferase) family protein
arTal_v1_Chr5_+_9597307_9597307 0.02 AT5G27240.2
AT5G27240
DNAJ heat shock N-terminal domain-containing protein
arTal_v1_Chr1_+_4197396_4197396 0.02 AT1G12340.1
AT1G12340
Cornichon family protein
arTal_v1_Chr2_-_1206249_1206249 0.02 AT2G03930.2
AT2G03930
hypothetical protein (DUF239)
arTal_v1_Chr1_-_19767334_19767507 0.02 AT1G53040.1
AT1G53040.4
AT1G53040.6
AT1G53040.5
AT1G53040.2
AT1G53040.3
AT1G53040
tRNA (met) cytidine acetyltransferase, putative (DUF616)
arTal_v1_Chr1_+_22452573_22452573 0.02 AT1G60980.1
GA20OX4
gibberellin 20-oxidase 4
arTal_v1_Chr5_+_9597552_9597552 0.02 AT5G27240.3
AT5G27240
DNAJ heat shock N-terminal domain-containing protein
arTal_v1_Chr4_+_7104510_7104510 0.02 AT4G11810.1
AT4G11810.2
AT4G11810
Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein
arTal_v1_Chr2_-_13056384_13056384 0.02 AT2G30650.2
AT2G30650.1
AT2G30650
ATP-dependent caseinolytic (Clp) protease/crotonase family protein
arTal_v1_Chr5_+_14690436_14690436 0.02 AT5G37140.1
AT5G37140
P-loop containing nucleoside triphosphate hydrolases superfamily protein
arTal_v1_Chr2_+_12689171_12689171 0.02 AT2G29680.2
CDC6
cell division control 6
arTal_v1_Chr1_+_8117286_8117286 0.02 AT1G22930.1
AT1G22930
T-complex protein 11
arTal_v1_Chr1_+_8117732_8117732 0.02 AT1G22930.2
AT1G22930
T-complex protein 11
arTal_v1_Chr3_+_17385161_17385161 0.01 AT3G47210.1
AT3G47210
hypothetical protein (DUF247)
arTal_v1_Chr5_+_14783436_14783436 0.01 AT5G37330.1
AT5G37330

arTal_v1_Chr1_+_12427475_12427475 0.01 AT1G34120.5
IP5PI
inositol polyphosphate 5-phosphatase I
arTal_v1_Chr5_-_9382331_9382331 0.01 AT5G26590.1
AT5G26590

arTal_v1_Chr1_-_18632039_18632039 0.01 AT1G50300.1
AT1G50300.2
TAF15
TBP-associated factor 15
arTal_v1_Chr1_-_11406017_11406017 0.01 AT1G31810.2
AFH14
Formin Homology 14
arTal_v1_Chr1_-_5898728_5898728 0.01 AT1G17240.1
RLP2
receptor like protein 2
arTal_v1_Chr1_+_761261_761282 0.01 AT1G03160.3
AT1G03160.1
AT1G03160.2
AT1G03160.4
FZL
FZO-like protein
arTal_v1_Chr4_-_5271148_5271148 0.01 AT4G08340.1
AT4G08340

arTal_v1_Chr1_+_13018289_13018289 0.01 AT1G35400.1
AT1G35400
hypothetical protein (DUF1184)
arTal_v1_Chr1_+_21729913_21729913 0.01 AT1G58525.1
AT1G58520.3
AT1G58525
RXW8
GDSL-like lipase/acylhydrolase superfamily protein
GDSL-like lipase/acylhydrolase superfamily protein
arTal_v1_Chr5_+_9343785_9343785 0.01 AT5G26650.1
AGL36
AGAMOUS-like 36
arTal_v1_Chr1_+_10531831_10531831 0.01 AT1G30030.1
AT1G30030

arTal_v1_Chr1_-_5898931_5898931 0.01 AT1G17240.2
RLP2
receptor like protein 2
arTal_v1_Chr1_-_18764367_18764367 0.01 AT1G50650.1
AT1G50650
Stigma-specific Stig1 family protein
arTal_v1_Chr1_-_8266048_8266048 0.01 AT1G23300.1
AT1G23300
MATE efflux family protein
arTal_v1_Chr3_+_21884426_21884520 0.00 AT3G59190.2
AT3G59190.1
AT3G59190
F-box/RNI-like superfamily protein
arTal_v1_Chr1_-_17683629_17683719 0.00 AT1G47960.1
AT1G47960.2
C/VIF1
cell wall / vacuolar inhibitor of fructosidase 1
arTal_v1_Chr2_-_6728183_6728183 0.00 AT2G15420.1
AT2G15420
myosin heavy chain-like protein
arTal_v1_Chr1_+_25701770_25701770 0.00 AT1G68500.1
AT1G68500
hypothetical protein
arTal_v1_Chr3_+_11177290_11177290 0.00 AT3G29210.1
AT3G29210

arTal_v1_Chr1_+_24909178_24909178 0.00 AT1G66780.1
AT1G66780
MATE efflux family protein
arTal_v1_Chr2_-_1037675_1037675 0.00 AT2G03430.1
AT2G03430
Ankyrin repeat family protein
arTal_v1_Chr3_+_22492811_22492811 0.00 AT3G60870.1
AHL18
AT-hook motif nuclear-localized protein 18
arTal_v1_Chr3_+_17278542_17278542 0.00 AT3G46910.1
AT3G46910
Cullin family protein

Network of associatons between targets according to the STRING database.

First level regulatory network of AT1G14350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0009769 photosynthesis, light harvesting in photosystem II(GO:0009769) positive regulation of reactive oxygen species biosynthetic process(GO:1903428)
0.1 0.3 GO:0009093 cysteine catabolic process(GO:0009093)
0.1 0.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 0.2 GO:0002009 establishment of planar polarity(GO:0001736) morphogenesis of a polarized epithelium(GO:0001738) morphogenesis of an epithelium(GO:0002009) tissue morphogenesis(GO:0048729)
0.0 0.5 GO:0009610 response to symbiotic fungus(GO:0009610)
0.0 0.2 GO:0010444 G1/S transition of mitotic cell cycle(GO:0000082) guard mother cell cytokinesis(GO:0010235) guard mother cell differentiation(GO:0010444)
0.0 0.3 GO:0045962 positive regulation of development, heterochronic(GO:0045962)
0.0 0.5 GO:0010112 regulation of systemic acquired resistance(GO:0010112)
0.0 0.1 GO:0015689 molybdate ion transport(GO:0015689)
0.0 0.1 GO:0010184 cytokinin transport(GO:0010184)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0009090 homoserine biosynthetic process(GO:0009090)
0.0 0.1 GO:0098795 production of lsiRNA involved in RNA interference(GO:0010599) mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.5 GO:0019761 S-glycoside biosynthetic process(GO:0016144) glycosinolate biosynthetic process(GO:0019758) glucosinolate biosynthetic process(GO:0019761)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0030076 thylakoid light-harvesting complex(GO:0009503) PSII associated light-harvesting complex II(GO:0009517) light-harvesting complex(GO:0030076)
0.0 0.3 GO:0009538 photosystem I reaction center(GO:0009538)
0.0 0.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0010005 cortical microtubule, transverse to long axis(GO:0010005)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016781 phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0016984 ribulose-bisphosphate carboxylase activity(GO:0016984)
0.0 0.7 GO:0016168 chlorophyll binding(GO:0016168)
0.0 0.1 GO:0004412 homoserine dehydrogenase activity(GO:0004412)
0.0 0.1 GO:0032131 alkylated DNA binding(GO:0032131)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0015098 molybdate ion transmembrane transporter activity(GO:0015098)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0070138 ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.0 0.3 GO:0019239 deaminase activity(GO:0019239)
0.0 0.0 GO:0050577 GDP-L-fucose synthase activity(GO:0050577)
0.0 0.2 GO:0022839 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism