ISMARA results: AACACUG

Motif ID: AACACUG

Z-value: 0.494

Mature miRNA associated with seed AACACUG:

Name	miRBase Accession
hsa-miR-141-3p	MIMAT0000432
hsa-miR-200a-3p	MIMAT0000682

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Showing 1 to 20 of 200 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_72375167	0.884	ENST00000001146.2	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr5_-_43313574	0.544	ENST00000325110.6 ENST00000433297.2	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr1_-_150208291	0.525	ENST00000533654.1	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_-_115375107	0.516	ENST00000545380.1 ENST00000452722.3 ENST00000537058.1 ENST00000536727.1 ENST00000542447.2 ENST00000331581.6	CADM1	cell adhesion molecule 1
chr1_-_6453399	0.504	ENST00000608083.1	ACOT7	acyl-CoA thioesterase 7
chr7_-_111846435	0.445	ENST00000437633.1 ENST00000428084.1	DOCK4	dedicator of cytokinesis 4
chr12_+_4382917	0.406	ENST00000261254.3	CCND2	cyclin D2
chr11_-_87908600	0.389	ENST00000531138.1 ENST00000526372.1 ENST00000243662.6	RAB38	RAB38, member RAS oncogene family
chr1_-_179198702	0.387	ENST00000502732.1	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase
chr11_-_2158507	0.376	ENST00000381392.1 ENST00000381395.1 ENST00000418738.2	IGF2	insulin-like growth factor 2 (somatomedin A)
chr20_+_3776371	0.361	ENST00000245960.5	CDC25B	cell division cycle 25B
chr1_+_84543734	0.316	ENST00000370689.2	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr10_+_11865347	0.302	ENST00000277570.5	PROSER2	proline and serine-rich protein 2
chr13_-_30881621	0.295	ENST00000380615.3	KATNAL1	katanin p60 subunit A-like 1
chr10_-_33623564	0.283	ENST00000374875.1 ENST00000374822.4	NRP1	neuropilin 1
chr17_-_8534067	0.279	ENST00000360416.3 ENST00000269243.4	MYH10	myosin, heavy chain 10, non-muscle
chr9_+_116638562	0.275	ENST00000374126.5 ENST00000288466.7	ZNF618	zinc finger protein 618
chr3_+_158991025	0.273	ENST00000337808.6	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chr8_-_95908902	0.273	ENST00000520509.1	CCNE2	cyclin E2
chr13_+_98605902	0.263	ENST00000460070.1 ENST00000481455.1 ENST00000261574.5 ENST00000493281.1 ENST00000463157.1 ENST00000471898.1 ENST00000489058.1 ENST00000481689.1	IPO5	importin 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 75 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:2001037	tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1	0.5	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.5	GO:1900533	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0	0.5	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	0.4	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1	0.4	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.4	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.4	GO:0007144	female meiosis I(GO:0007144)
0.0	0.4	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.3	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.3	GO:0021592	fourth ventricle development(GO:0021592)
0.1	0.3	GO:1902378	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0	0.3	GO:0097338	response to clozapine(GO:0097338)
0.0	0.3	GO:1903575	cornified envelope assembly(GO:1903575)
0.0	0.3	GO:0051013	microtubule severing(GO:0051013)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.2	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0	0.2	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0	0.2	GO:0036510	trimming of terminal mannose on C branch(GO:0036510)
0.0	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)

Gene overrepresentation in cellular_component category:

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Showing 1 to 19 of 19 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	GO:0000812	Swr1 complex(GO:0000812)
0.1	0.4	GO:0031905	early endosome lumen(GO:0031905)
0.1	0.4	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.4	GO:0016600	flotillin complex(GO:0016600)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.3	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	0.3	GO:0097513	myosin II filament(GO:0097513)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0070876	SOSS complex(GO:0070876)
0.0	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.2	GO:0030914	SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0	0.1	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.0	GO:0071203	WASH complex(GO:0071203)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 48 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.5	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.4	GO:0035651	AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.4	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.3	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.3	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	0.2	GO:0008457	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0	0.2	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0	0.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:1904047	S-adenosyl-L-methionine binding(GO:1904047)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)

Gene overrepresentation in C2:CP category:

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Showing 1 to 8 of 8 entries

Total log-likelihood	Term	Description
0.8	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.7	PID_EPHA2_FWD_PATHWAY	EPHA2 forward signaling
0.5	SA_G2_AND_M_PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5	PID_IL2_STAT5_PATHWAY	IL2 signaling events mediated by STAT5
0.4	PID_IL3_PATHWAY	IL3-mediated signaling events
0.3	PID_VEGF_VEGFR_PATHWAY	VEGF and VEGFR signaling network
0.3	PID_S1P_S1P4_PATHWAY	S1P4 pathway
0.3	SA_REG_CASCADE_OF_CYCLIN_EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 14 of 14 entries

Total log-likelihood	Term	Description
0.9	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.6	REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6	REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING	Genes involved in Spry regulation of FGF signaling
0.6	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.6	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.5	REACTOME_CHOLESTEROL_BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.4	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.4	REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	REACTOME_G0_AND_EARLY_G1	Genes involved in G0 and Early G1
0.3	REACTOME_GLUCURONIDATION	Genes involved in Glucuronidation
0.3	REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	REACTOME_ERKS_ARE_INACTIVATED	Genes involved in ERKs are inactivated
0.2	REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins