Motif ID: AACAGUC

Z-value: 0.420


Mature miRNA associated with seed AACAGUC:

NamemiRBase Accession
hsa-miR-132-3p MIMAT0000426
hsa-miR-212-3p MIMAT0000269



Activity profile for motif AACAGUC.

activity profile for motif AACAGUC


Sorted Z-values histogram for motif AACAGUC

Sorted Z-values for motif AACAGUC



Network of associatons between targets according to the STRING database.



First level regulatory network of AACAGUC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_14813160 1.393 ENST00000338981.3
 USP9Y
ubiquitin specific peptidase 9, Y-linked
chr6_-_132272504 0.707 ENST00000367976.3
 CTGF
connective tissue growth factor
chr9_-_3525968 0.688 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
 RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr1_-_217262969 0.619 ENST00000361525.3
 ESRRG
estrogen-related receptor gamma
chr14_-_95786200 0.579 ENST00000298912.4
 CLMN
calmin (calponin-like, transmembrane)
chr3_-_114790179 0.532 ENST00000462705.1
 ZBTB20
zinc finger and BTB domain containing 20
chr18_-_74207146 0.521 ENST00000443185.2
 ZNF516
zinc finger protein 516
chr5_+_42423872 0.519 ENST00000230882.4
ENST00000357703.3
 GHR

growth hormone receptor

chr1_+_244214577 0.517 ENST00000358704.4
 ZBTB18
zinc finger and BTB domain containing 18
chr5_+_50678921 0.512 ENST00000230658.7
 ISL1
ISL LIM homeobox 1
chr14_-_90085458 0.466 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
 FOXN3


forkhead box N3


chr5_-_111093406 0.432 ENST00000379671.3
 NREP
neuronal regeneration related protein
chr5_-_146833485 0.402 ENST00000398514.3
 DPYSL3
dihydropyrimidinase-like 3
chr11_-_111175739 0.379 ENST00000532918.1
 COLCA1
colorectal cancer associated 1
chr5_+_153825510 0.365 ENST00000297109.6
 SAP30L
SAP30-like
chr20_-_7921090 0.363 ENST00000378789.3
 HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr3_+_197687071 0.311 ENST00000482695.1
ENST00000330198.4
ENST00000419117.1
ENST00000420910.2
ENST00000332636.5
 LMLN




leishmanolysin-like (metallopeptidase M8 family)




chr20_-_4982132 0.283 ENST00000338244.1
ENST00000424750.2
 SLC23A2

solute carrier family 23 (ascorbic acid transporter), member 2

chr17_+_61699766 0.255 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
 MAP3K3



mitogen-activated protein kinase kinase kinase 3



chr8_-_103876965 0.251 ENST00000337198.5
 AZIN1
antizyme inhibitor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:0034059 response to anoxia(GO:0034059)
0.2 0.7 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.2 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.2 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.2 0.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID_ALK1_PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA