Motif ID: AAGGCAC

Z-value: 1.242


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124-3p.1 MIMAT0000422



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_149365827 5.419 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr21_+_36041688 3.644 ENST00000360731.3
ENST00000349499.2
CLIC6

chloride intracellular channel 6

chr1_+_228870824 3.451 ENST00000366691.3
RHOU
ras homolog family member U
chr18_-_45663666 3.267 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr6_-_90121938 3.021 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr4_+_25657444 2.976 ENST00000504570.1
ENST00000382051.3
SLC34A2

solute carrier family 34 (type II sodium/phosphate contransporter), member 2

chr19_+_709101 2.896 ENST00000338448.5
PALM
paralemmin
chr14_+_67999999 2.826 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr19_-_7990991 2.704 ENST00000318978.4
CTXN1
cortexin 1
chr5_-_101632153 2.548 ENST00000310954.6
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr17_+_68165657 2.528 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr14_+_77648167 2.430 ENST00000554346.1
ENST00000298351.4
TMEM63C

transmembrane protein 63C

chr15_+_45315302 2.334 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr5_-_100238956 2.326 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr15_-_49255632 2.320 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr3_+_160473996 2.277 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr19_+_32896697 2.224 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr6_+_17281573 2.206 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr9_-_89562104 2.167 ENST00000298743.7
GAS1
growth arrest-specific 1
chr7_+_121513143 2.121 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr4_+_95679072 2.073 ENST00000515059.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr13_-_86373536 1.993 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_87794150 1.990 ENST00000370544.5
LMO4
LIM domain only 4
chr6_-_134639180 1.902 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr6_+_16129308 1.889 ENST00000356840.3
ENST00000349606.4
MYLIP

myosin regulatory light chain interacting protein

chr19_-_14316980 1.875 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr19_+_17581253 1.850 ENST00000252595.7
ENST00000598424.1
SLC27A1

solute carrier family 27 (fatty acid transporter), member 1

chr1_+_57110972 1.843 ENST00000371244.4
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr3_-_66551351 1.840 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr6_+_135502466 1.826 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr13_+_24734844 1.809 ENST00000382108.3
SPATA13
spermatogenesis associated 13
chr5_-_124080203 1.796 ENST00000504926.1
ZNF608
zinc finger protein 608
chr12_-_89919965 1.777 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr5_-_16509101 1.764 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr16_+_28303804 1.748 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr12_-_89918522 1.722 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr9_-_3525968 1.702 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr8_+_120885949 1.685 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr5_-_9546180 1.671 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr8_+_67976593 1.599 ENST00000262210.5
ENST00000412460.1
CSPP1

centrosome and spindle pole associated protein 1

chr7_-_124405681 1.575 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_151483855 1.485 ENST00000427934.2
ENST00000271636.7
CGN

cingulin

chr20_+_51588873 1.474 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chr3_+_49449636 1.431 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr5_+_75699040 1.422 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr1_-_204329013 1.414 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr1_+_210406121 1.410 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr20_-_32031680 1.401 ENST00000217381.2
SNTA1
syntrophin, alpha 1
chr4_+_41362796 1.384 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1




LIM and calponin homology domains 1




chr1_+_61547894 1.383 ENST00000403491.3
NFIA
nuclear factor I/A
chr1_+_114472222 1.383 ENST00000369558.1
ENST00000369561.4
HIPK1

homeodomain interacting protein kinase 1

chr6_-_154831779 1.370 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr3_+_183353356 1.366 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24








kelch-like family member 24








chr9_+_136325089 1.330 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1


calcium channel flower domain containing 1


chrX_-_132549506 1.321 ENST00000370828.3
GPC4
glypican 4
chr8_+_17354587 1.305 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr10_+_72164135 1.288 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr6_+_28109703 1.282 ENST00000457389.2
ENST00000330236.6
ZKSCAN8

zinc finger with KRAB and SCAN domains 8

chr16_+_69599861 1.277 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr8_-_29120580 1.264 ENST00000524189.1
KIF13B
kinesin family member 13B
chr18_-_30050395 1.255 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr14_-_61190754 1.235 ENST00000216513.4
SIX4
SIX homeobox 4
chr11_-_95522907 1.227 ENST00000358780.5
ENST00000542135.1
FAM76B

family with sequence similarity 76, member B

chr12_+_93771659 1.222 ENST00000337179.5
ENST00000415493.2
NUDT4

nudix (nucleoside diphosphate linked moiety X)-type motif 4

chr14_-_95786200 1.209 ENST00000298912.4
CLMN
calmin (calponin-like, transmembrane)
chr6_+_138483058 1.204 ENST00000251691.4
KIAA1244
KIAA1244
chr5_+_149340282 1.202 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr5_+_127419449 1.198 ENST00000262461.2
ENST00000343225.4
SLC12A2

solute carrier family 12 (sodium/potassium/chloride transporter), member 2

chr9_-_20622478 1.194 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr7_+_3340989 1.193 ENST00000404826.2
ENST00000389531.3
SDK1

sidekick cell adhesion molecule 1

chr4_+_81951957 1.180 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr3_-_114790179 1.169 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_39760783 1.161 ENST00000398904.2
ENST00000538976.1
DAAM2

dishevelled associated activator of morphogenesis 2

chr2_+_231729615 1.160 ENST00000326427.6
ENST00000335005.6
ENST00000326407.6
ITM2C


integral membrane protein 2C


chr9_-_139922631 1.148 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr2_+_219536749 1.147 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
STK36



serine/threonine kinase 36



chr6_+_1312675 1.140 ENST00000296839.2
FOXQ1
forkhead box Q1
chr7_+_89841000 1.130 ENST00000287908.3
STEAP2
STEAP family member 2, metalloreductase
chr19_+_10527449 1.119 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chr3_+_69812877 1.117 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr6_+_148663729 1.115 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr22_+_25465786 1.093 ENST00000401395.1
KIAA1671
KIAA1671
chr2_-_216946500 1.089 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr16_-_68482440 1.076 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr19_+_13135386 1.067 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX


nuclear factor I/X (CCAAT-binding transcription factor)


chrX_-_112084043 1.066 ENST00000304758.1
AMOT
angiomotin
chr7_+_17338239 1.066 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr12_+_124196865 1.054 ENST00000330342.3
ATP6V0A2
ATPase, H+ transporting, lysosomal V0 subunit a2
chr6_+_143929307 1.045 ENST00000427704.2
ENST00000305766.6
PHACTR2

phosphatase and actin regulator 2

chr10_+_71211212 1.040 ENST00000373290.2
TSPAN15
tetraspanin 15
chr1_+_92495528 1.034 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr6_+_71998506 1.033 ENST00000370435.4
OGFRL1
opioid growth factor receptor-like 1
chr19_-_33793430 1.026 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr18_-_47721447 1.013 ENST00000285039.7
MYO5B
myosin VB
chr5_+_140254884 1.012 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr1_-_1535455 1.012 ENST00000422725.1
C1orf233
chromosome 1 open reading frame 233
chr5_+_140248518 1.010 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr6_-_154677900 1.003 ENST00000265198.4
ENST00000520261.1
IPCEF1

interaction protein for cytohesin exchange factors 1

chr5_+_153825510 1.001 ENST00000297109.6
SAP30L
SAP30-like
chr9_+_126773880 0.998 ENST00000373615.4
LHX2
LIM homeobox 2
chr6_+_46097711 0.993 ENST00000321037.4
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr5_+_140227048 0.982 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr5_+_140213815 0.976 ENST00000525929.1
ENST00000378125.3
PCDHA7

protocadherin alpha 7

chr10_-_52383644 0.976 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr5_-_133968529 0.969 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr17_+_53342311 0.965 ENST00000226067.5
HLF
hepatic leukemia factor
chr11_-_72853091 0.954 ENST00000311172.7
ENST00000409314.1
FCHSD2

FCH and double SH3 domains 2

chr11_+_113930291 0.954 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr17_-_42200996 0.951 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5



histone deacetylase 5



chr5_+_140220769 0.949 ENST00000531613.1
ENST00000378123.3
PCDHA8

protocadherin alpha 8

chr8_+_74206829 0.946 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr2_+_54951679 0.940 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr18_-_53255766 0.938 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr17_+_29718642 0.933 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr4_-_168155730 0.925 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr12_-_65146636 0.923 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr2_+_85766280 0.919 ENST00000306434.3
MAT2A
methionine adenosyltransferase II, alpha
chr5_-_131826457 0.911 ENST00000437654.1
ENST00000245414.4
IRF1

interferon regulatory factor 1

chr3_-_141868357 0.906 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr22_+_29279552 0.903 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr6_-_99395787 0.898 ENST00000369244.2
ENST00000229971.1
FBXL4

F-box and leucine-rich repeat protein 4

chr6_+_158957431 0.895 ENST00000367090.3
TMEM181
transmembrane protein 181
chr2_+_11295498 0.895 ENST00000295083.3
ENST00000441908.2
PQLC3

PQ loop repeat containing 3

chr1_-_169455169 0.883 ENST00000367804.4
ENST00000236137.5
SLC19A2

solute carrier family 19 (thiamine transporter), member 2

chr11_-_118023490 0.882 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr5_+_102201430 0.879 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr5_+_172483347 0.877 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF



CREB3 regulatory factor



chr2_+_88991162 0.875 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr11_+_7597639 0.862 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_-_118541743 0.859 ENST00000359236.5
VSIG10
V-set and immunoglobulin domain containing 10
chr11_+_73019282 0.851 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr4_+_129730779 0.828 ENST00000226319.6
PHF17
jade family PHD finger 1
chr12_+_121148228 0.825 ENST00000344651.4
UNC119B
unc-119 homolog B (C. elegans)
chr17_-_202579 0.824 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL


rabphilin 3A-like (without C2 domains)


chr5_+_56111361 0.820 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr11_+_61520075 0.806 ENST00000278836.5
MYRF
myelin regulatory factor
chr2_+_172378757 0.796 ENST00000409484.1
ENST00000321348.4
ENST00000375252.3
CYBRD1


cytochrome b reductase 1


chr11_-_74109422 0.793 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr12_-_15942309 0.792 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8


epidermal growth factor receptor pathway substrate 8


chr11_-_119252359 0.787 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr5_-_96478466 0.786 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr5_-_115910630 0.775 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_+_179923873 0.772 ENST00000367607.3
ENST00000491495.2
CEP350

centrosomal protein 350kDa

chr7_+_139026057 0.768 ENST00000541515.3
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr9_-_27573392 0.767 ENST00000380003.3
C9orf72
chromosome 9 open reading frame 72
chr17_+_7608511 0.767 ENST00000226091.2
EFNB3
ephrin-B3
chr8_+_143808605 0.760 ENST00000336138.3
THEM6
thioesterase superfamily member 6
chr4_-_89619386 0.759 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr8_+_110346546 0.759 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2


enhancer of yellow 2 homolog (Drosophila)


chrX_-_10645773 0.757 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_116915855 0.756 ENST00000295598.5
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr16_+_4364762 0.749 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr1_-_86174065 0.747 ENST00000370574.3
ENST00000431532.2
ZNHIT6

zinc finger, HIT-type containing 6

chr1_+_179050512 0.744 ENST00000367627.3
TOR3A
torsin family 3, member A
chr6_+_167412665 0.743 ENST00000366847.4
FGFR1OP
FGFR1 oncogene partner
chr1_+_201979645 0.737 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr1_-_234614849 0.733 ENST00000040877.1
TARBP1
TAR (HIV-1) RNA binding protein 1
chr4_-_170192185 0.731 ENST00000284637.9
SH3RF1
SH3 domain containing ring finger 1
chr2_-_96874553 0.729 ENST00000337288.5
ENST00000443962.1
STARD7

StAR-related lipid transfer (START) domain containing 7

chr4_+_7045042 0.728 ENST00000310074.7
ENST00000512388.1
TADA2B

transcriptional adaptor 2B

chr20_-_18038521 0.726 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr4_-_2264015 0.720 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr22_+_24666763 0.714 ENST00000437398.1
ENST00000421374.1
ENST00000314328.9
ENST00000541492.1
SPECC1L



sperm antigen with calponin homology and coiled-coil domains 1-like



chr15_+_40763150 0.707 ENST00000306243.5
ENST00000559991.1
CHST14

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14

chr7_-_112430647 0.703 ENST00000312814.6
TMEM168
transmembrane protein 168
chr6_-_79787902 0.701 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr20_-_45035223 0.701 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2



engulfment and cell motility 2



chr3_+_119187785 0.696 ENST00000295588.4
ENST00000476573.1
POGLUT1

protein O-glucosyltransferase 1

chr16_+_71929397 0.687 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
IST1








increased sodium tolerance 1 homolog (yeast)








chr5_+_131705438 0.686 ENST00000245407.3
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr5_-_473135 0.678 ENST00000342584.3
CTD-2228K2.5
Uncharacterized protein
chr12_+_52445191 0.677 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr9_+_104161123 0.676 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189


zinc finger protein 189


chr19_-_3063099 0.676 ENST00000221561.8
AES
amino-terminal enhancer of split
chr2_-_97405775 0.675 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L




lectin, mannose-binding 2-like




chr6_+_133562472 0.672 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4



eyes absent homolog 4 (Drosophila)



chr13_+_88324870 0.671 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr1_+_15943995 0.669 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr21_-_34852304 0.666 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr12_+_111843749 0.662 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr18_+_72922710 0.661 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr11_+_121322832 0.659 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr8_+_95732095 0.658 ENST00000414645.2
DPY19L4
dpy-19-like 4 (C. elegans)
chr20_+_33292068 0.652 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr2_+_26915584 0.650 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr2_-_86564776 0.648 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1


receptor accessory protein 1


chr5_+_49961727 0.647 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8


poly (ADP-ribose) polymerase family, member 8


chr11_-_22851367 0.647 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr1_-_225840747 0.645 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chr15_+_41952591 0.645 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA



MGA, MAX dimerization protein



chr11_-_108093329 0.624 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr6_-_28220002 0.624 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr1_+_101361626 0.623 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr17_-_47841485 0.622 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr11_+_818902 0.620 ENST00000336615.4
PNPLA2
patatin-like phospholipase domain containing 2
chr2_-_230933709 0.616 ENST00000436869.1
ENST00000295190.4
SLC16A14

solute carrier family 16, member 14

chr11_+_129685707 0.612 ENST00000281441.3
TMEM45B
transmembrane protein 45B
chr14_+_23067146 0.610 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr19_-_55881741 0.605 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11


interleukin 11


chr10_-_28034989 0.604 ENST00000375790.5
MKX
mohawk homeobox

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.8 2.3 GO:0006059 hexitol metabolic process(GO:0006059)
0.6 1.8 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.6 1.7 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.4 1.3 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.4 2.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 1.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.4 0.4 GO:0032506 cytokinetic process(GO:0032506)
0.4 1.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.4 3.0 GO:0071233 cellular response to leucine(GO:0071233)
0.4 0.7 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.4 1.1 GO:0009405 pathogenesis(GO:0009405)
0.4 1.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.4 2.9 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.4 2.9 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 2.0 GO:0060005 vestibular reflex(GO:0060005)
0.3 1.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 3.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 0.6 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 2.2 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.3 0.3 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.3 1.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.8 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.3 1.5 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.2 2.3 GO:0015677 copper ion import(GO:0015677)
0.2 3.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 0.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 1.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 0.9 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 1.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 0.9 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 0.7 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 0.9 GO:0018032 protein amidation(GO:0018032)
0.2 1.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.9 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.9 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 1.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 1.0 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.2 0.6 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.2 0.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 1.1 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 2.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 0.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.5 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 2.4 GO:0042659 regulation of cell fate specification(GO:0042659)
0.2 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.4 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.2 2.6 GO:0055089 fatty acid homeostasis(GO:0055089)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.9 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 2.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.4 GO:0034059 response to anoxia(GO:0034059)
0.1 1.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.3 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.7 GO:0060023 soft palate development(GO:0060023)
0.1 0.6 GO:0060214 endocardium formation(GO:0060214)
0.1 1.0 GO:0032439 endosome localization(GO:0032439)
0.1 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.0 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.4 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.1 0.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.9 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.8 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.1 0.2 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.7 GO:0048254 snoRNA localization(GO:0048254)
0.1 1.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.1 GO:0098907 regulation of SA node cell action potential(GO:0098907)
0.1 1.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 1.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.3 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 1.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.4 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 1.2 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 1.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 1.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.6 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.7 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) regulation of type B pancreatic cell proliferation(GO:0061469) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.6 GO:0060179 male mating behavior(GO:0060179)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 1.0 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1 1.1 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 1.1 GO:0048863 stem cell differentiation(GO:0048863)
0.1 0.4 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 1.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.1 0.2 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 1.5 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 1.2 GO:0007379 segment specification(GO:0007379)
0.1 0.6 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 0.3 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.8 GO:0016198 axon choice point recognition(GO:0016198)
0.1 1.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 0.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:0010816 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 2.2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.1 0.6 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 1.4 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 1.7 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.3 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.3 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.1 1.0 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0051660 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
0.1 1.0 GO:0015671 oxygen transport(GO:0015671)
0.1 0.2 GO:0032455 nerve growth factor processing(GO:0032455) neurotrophin production(GO:0032898)
0.0 1.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 2.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0051170 nuclear import(GO:0051170)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.4 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.5 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 4.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.1 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:0072513 semicircular canal morphogenesis(GO:0048752) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 1.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0046676 negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.3 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.2 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 6.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.0 0.1 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 1.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.6 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 1.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.7 GO:0007625 grooming behavior(GO:0007625)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 2.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.7 GO:0060761 negative regulation of response to cytokine stimulus(GO:0060761)
0.0 0.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.3 GO:1904262 TORC2 signaling(GO:0038203) negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.8 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0042113 B cell activation(GO:0042113)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.3 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 0.1 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0001764 neuron migration(GO:0001764)
0.0 0.1 GO:0051701 interaction with host(GO:0051701)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.3 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0090212 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 1.0 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.3 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760)
0.0 1.2 GO:0030888 regulation of B cell proliferation(GO:0030888)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.3 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.4 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0042755 eating behavior(GO:0042755)
0.0 0.8 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.9 GO:0003407 neural retina development(GO:0003407)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.6 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.8 GO:0061718 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.0 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.0 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.1 GO:0007588 excretion(GO:0007588)
0.0 0.0 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560)
0.0 0.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0048477 oogenesis(GO:0048477)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0072534 perineuronal net(GO:0072534)
0.7 2.0 GO:0005667 transcription factor complex(GO:0005667)
0.5 3.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 0.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 0.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 2.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 2.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.5 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.7 GO:0030914 STAGA complex(GO:0030914)
0.1 0.9 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 0.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.1 1.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 2.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0089701 U2AF(GO:0089701)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 3.8 GO:0031526 brush border membrane(GO:0031526)
0.1 1.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.9 GO:0090543 Flemming body(GO:0090543)
0.0 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 4.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.1 GO:0032991 macromolecular complex(GO:0032991)
0.0 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.8 GO:0002102 podosome(GO:0002102)
0.0 3.8 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0044754 autolysosome(GO:0044754)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 1.3 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 0.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0034774 secretory granule lumen(GO:0034774)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.6 2.9 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.4 1.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 1.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 0.4 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.4 1.1 GO:0090541 MIT domain binding(GO:0090541)
0.3 1.3 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.3 1.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 3.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 0.9 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 1.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.3 1.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 2.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.7 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.2 2.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.9 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.2 1.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 1.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 1.1 GO:0043532 angiostatin binding(GO:0043532)
0.2 1.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 0.3 GO:0015184 sulfur amino acid transmembrane transporter activity(GO:0000099) L-cystine transmembrane transporter activity(GO:0015184) modified amino acid transmembrane transporter activity(GO:0072349)
0.2 0.7 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 0.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 0.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 1.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.4 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.5 GO:0043398 HLH domain binding(GO:0043398)
0.1 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 3.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 2.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.8 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.4 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.7 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 1.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 1.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 2.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 4.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 1.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.3 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 2.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 2.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 1.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 3.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 2.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 1.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0071208 histone pre-mRNA stem-loop binding(GO:0071207) histone pre-mRNA DCP binding(GO:0071208)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 2.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 2.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 1.8 GO:0051287 NAD binding(GO:0051287)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 3.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.9 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 PID_EPO_PATHWAY EPO signaling pathway
0.1 1.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 1.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 4.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 5.1 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 2.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.8 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 2.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.1 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID_LPA4_PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 2.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 1.8 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.1 0.3 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.1 1.5 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.5 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.5 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.7 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.2 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 2.1 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.7 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 5.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 3.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.0 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.7 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 1.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.0 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.5 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.8 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.4 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.1 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription