Motif ID: AAUCUCA

Z-value: 0.112


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a-5p MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_14204389 0.222 ENST00000360954.2
 HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr9_-_20622478 0.137 ENST00000355930.6
ENST00000380338.4
 MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr17_+_53342311 0.116 ENST00000226067.5
 HLF
hepatic leukemia factor
chr4_-_105416039 0.108 ENST00000394767.2
 CXXC4
CXXC finger protein 4
chr4_+_3076388 0.076 ENST00000355072.5
 HTT
huntingtin
chr7_-_139876812 0.070 ENST00000397560.2
 JHDM1D
lysine (K)-specific demethylase 7A
chrX_-_20284958 0.064 ENST00000379565.3
 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr5_+_149109825 0.060 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
 PPARGC1B


peroxisome proliferator-activated receptor gamma, coactivator 1 beta


chr11_-_32452357 0.052 ENST00000379079.2
ENST00000530998.1
 WT1

Wilms tumor 1

chr7_+_12250886 0.046 ENST00000444443.1
ENST00000396667.3
 TMEM106B

transmembrane protein 106B

chr5_-_178054105 0.042 ENST00000316308.4
 CLK4
CDC-like kinase 4
chr8_-_114389353 0.032 ENST00000343508.3
 CSMD3
CUB and Sushi multiple domains 3
chr2_-_172967621 0.029 ENST00000234198.4
ENST00000466293.2
 DLX2

distal-less homeobox 2

chr2_+_231921574 0.026 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
 PSMD1



proteasome (prosome, macropain) 26S subunit, non-ATPase, 1



chr12_+_50344516 0.019 ENST00000199280.3
ENST00000550862.1
 AQP2

aquaporin 2 (collecting duct)

chrX_+_122993827 0.016 ENST00000371199.3
 XIAP
X-linked inhibitor of apoptosis
chr6_+_42749759 0.015 ENST00000314073.5
 GLTSCR1L
GLTSCR1-like
chr6_-_44265411 0.015 ENST00000371505.4
 TCTE1
t-complex-associated-testis-expressed 1
chr4_-_113437328 0.012 ENST00000313341.3
 NEUROG2
neurogenin 2
chr15_+_40733387 0.011 ENST00000416165.1
 BAHD1
bromo adjacent homology domain containing 1
chr13_-_31038370 0.011 ENST00000399489.1
ENST00000339872.4
 HMGB1

high mobility group box 1

chr1_+_63788730 0.009 ENST00000371116.2
 FOXD3
forkhead box D3
chr13_-_45915221 0.008 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
 TPT1




tumor protein, translationally-controlled 1




chr2_-_242212227 0.008 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
 HDLBP








high density lipoprotein binding protein








chrX_+_23352133 0.008 ENST00000379361.4
 PTCHD1
patched domain containing 1
chr5_+_122424816 0.006 ENST00000407847.4
 PRDM6
PR domain containing 6
chr18_-_22932080 0.005 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
 ZNF521


zinc finger protein 521


chr18_+_59992527 0.004 ENST00000586569.1
 TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)