Motif ID: AAUGCCC

Z-value: 0.378


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365a-3p MIMAT0000710
hsa-miR-365b-3p MIMAT0022834



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Showing 1 to 20 of 157 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_149365827 2.137 ENST00000344721.4
 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr1_-_46598284 1.313 ENST00000423209.1
ENST00000262741.5
 PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr17_+_68165657 0.939 ENST00000243457.3
 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr6_-_134639180 0.771 ENST00000367858.5
 SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_61547894 0.594 ENST00000403491.3
 NFIA
nuclear factor I/A
chr3_+_23986748 0.557 ENST00000312521.4
 NR1D2
nuclear receptor subfamily 1, group D, member 2
chr17_+_55333876 0.548 ENST00000284073.2
 MSI2
musashi RNA-binding protein 2
chr11_+_2466218 0.493 ENST00000155840.5
 KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr20_-_39317868 0.455 ENST00000373313.2
 MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr5_-_100238956 0.402 ENST00000231461.5
 ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr6_+_16129308 0.354 ENST00000356840.3
ENST00000349606.4
 MYLIP

myosin regulatory light chain interacting protein

chr12_-_89918522 0.350 ENST00000529983.2
 GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr12_-_89919965 0.344 ENST00000548729.1
 POC1B-GALNT4
POC1B-GALNT4 readthrough
chr5_+_172483347 0.335 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
 CREBRF



CREB3 regulatory factor



chr6_-_46138676 0.332 ENST00000371383.2
ENST00000230565.3
 ENPP5

ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)

chr5_+_149109825 0.303 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
 PPARGC1B


peroxisome proliferator-activated receptor gamma, coactivator 1 beta


chr10_-_62149433 0.286 ENST00000280772.2
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_157189180 0.275 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
 NR4A2




nuclear receptor subfamily 4, group A, member 2




chr8_+_28351707 0.274 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
 FZD3


frizzled family receptor 3


chr12_+_74931551 0.260 ENST00000519948.2
 ATXN7L3B
ataxin 7-like 3B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.3 0.9 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.6 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.2 0.5 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.4 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.3 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0048864 stem cell development(GO:0048864)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.5 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.1 GO:0001227 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID_INSULIN_PATHWAY Insulin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1