Motif ID: ACAGUAC

Z-value: 0.655


Mature miRNA associated with seed ACAGUAC:

NamemiRBase Accession
hsa-miR-101-3p.1 MIMAT0000099



Activity profile for motif ACAGUAC.

activity profile for motif ACAGUAC


Sorted Z-values histogram for motif ACAGUAC

Sorted Z-values for motif ACAGUAC



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_15016725 2.187 ENST00000336079.3
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr11_-_115375107 1.139 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1





cell adhesion molecule 1





chr1_-_186649543 1.034 ENST00000367468.5
 PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_23712312 0.702 ENST00000290271.2
 STC1
stanniocalcin 1
chr12_+_93965451 0.663 ENST00000548537.1
 SOCS2
suppressor of cytokine signaling 2
chr7_-_148581251 0.655 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
 EZH2


enhancer of zeste homolog 2 (Drosophila)


chr3_+_3841108 0.546 ENST00000319331.3
 LRRN1
leucine rich repeat neuronal 1
chr5_-_127873659 0.518 ENST00000262464.4
 FBN2
fibrillin 2
chr21_+_35445827 0.506 ENST00000381151.3
ENST00000608209.1
 SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr8_-_72268889 0.469 ENST00000388742.4
 EYA1
eyes absent homolog 1 (Drosophila)
chr6_+_163148161 0.426 ENST00000337019.3
ENST00000366889.2
 PACRG

PARK2 co-regulated

chr11_-_95657231 0.405 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
 MTMR2



myotubularin related protein 2



chr9_-_3525968 0.398 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
 RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr17_+_60536002 0.372 ENST00000582809.1
 TLK2
tousled-like kinase 2
chr10_+_115803650 0.369 ENST00000369295.2
 ADRB1
adrenoceptor beta 1
chr1_-_244013384 0.345 ENST00000366539.1
 AKT3
v-akt murine thymoma viral oncogene homolog 3
chr21_-_15755446 0.331 ENST00000544452.1
ENST00000285667.3
 HSPA13

heat shock protein 70kDa family, member 13

chr1_+_205473720 0.328 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
 CDK18


cyclin-dependent kinase 18


chr14_+_85996471 0.324 ENST00000330753.4
 FLRT2
fibronectin leucine rich transmembrane protein 2
chr8_-_122653630 0.313 ENST00000303924.4
 HAS2
hyaluronan synthase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 1.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 0.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.7 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.4 GO:0003099 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.4 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.3 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.2 GO:0045210 FasL biosynthetic process(GO:0045210)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0045120 pronucleus(GO:0045120)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.3 1.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.5 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 0.4 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.5 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 0.4 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.3 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome