Motif ID: ACAUUCA
Z-value: 1.038
Mature miRNA associated with seed ACAUUCA:
| Name | miRBase Accession |
|---|---|
| hsa-miR-181a-5p | MIMAT0000256 |
| hsa-miR-181b-5p | MIMAT0000257 |
| hsa-miR-181c-5p | MIMAT0000258 |
| hsa-miR-181d-5p | MIMAT0002821 |
| hsa-miR-4262 | MIMAT0016894 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 213 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 18.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 1.0 | 3.8 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.0 | 2.9 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.3 | 2.8 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.2 | 2.8 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.8 | 2.3 | GO:0002071 | glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) |
| 0.0 | 2.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 1.9 | GO:0033173 | calcineurin-NFAT signaling cascade(GO:0033173) |
| 0.1 | 1.8 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.1 | 1.8 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.1 | 1.7 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.1 | 1.6 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.1 | 1.6 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 1.5 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.0 | 1.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 1.4 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 1.3 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.1 | 1.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 1.3 | GO:0007405 | neuroblast proliferation(GO:0007405) |
| 0.2 | 1.2 | GO:0071350 | interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 84 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.8 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 2.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 1.9 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 1.8 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 1.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.4 | 1.6 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.3 | 1.3 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 1.3 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.0 | 1.3 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 1.2 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 1.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 1.1 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.3 | 1.0 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.0 | 1.0 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 1.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 1.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.9 | GO:0031094 | platelet dense tubular network(GO:0031094) |
| 0.0 | 0.9 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.9 | GO:0005921 | gap junction(GO:0005921) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 129 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 19.8 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.4 | 2.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 2.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 2.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.2 | 2.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.1 | 2.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 2.1 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 2.0 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.3 | 1.3 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.2 | 1.2 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 1.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 1.1 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 1.1 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 1.1 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.2 | 1.0 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.2 | 1.0 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.1 | 1.0 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 1.0 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.3 | 0.9 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.1 | 0.9 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 25 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 2.2 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 1.4 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.0 | 1.2 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.1 | 1.0 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 1.0 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 1.0 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.0 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.1 | 0.8 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.8 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.8 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.8 | PID_EPO_PATHWAY | EPO signaling pathway |
| 0.0 | 0.6 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.6 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.6 | PID_NFAT_3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.5 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.1 | 0.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.0 | 0.4 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.0 | 0.4 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.0 | 0.4 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 36 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.1 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 2.5 | REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in RORA Activates Circadian Expression |
| 0.1 | 2.0 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 2.0 | REACTOME_DAG_AND_IP3_SIGNALING | Genes involved in DAG and IP3 signaling |
| 0.1 | 1.8 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
| 0.2 | 1.2 | REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION | Genes involved in Binding and entry of HIV virion |
| 0.0 | 1.1 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 1.0 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.9 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.0 | 0.9 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.9 | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.0 | 0.8 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.8 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.0 | 0.8 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.7 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 0.7 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.7 | REACTOME_SPHINGOLIPID_METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.0 | 0.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.5 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
