Motif ID: ACUGGCC

Z-value: 0.393


Mature miRNA associated with seed ACUGGCC:

NamemiRBase Accession
hsa-miR-193a-3p MIMAT0000459
hsa-miR-193b-3p MIMAT0002819



Activity profile for motif ACUGGCC.

activity profile for motif ACUGGCC


Sorted Z-values histogram for motif ACUGGCC

Sorted Z-values for motif ACUGGCC



Network of associatons between targets according to the STRING database.



First level regulatory network of ACUGGCC

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 120 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_55524085 1.262 ENST00000412167.2
ENST00000288135.5
 KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr6_-_29527702 1.246 ENST00000377050.4
 UBD
ubiquitin D
chr17_+_68165657 1.100 ENST00000243457.3
 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr22_-_39548627 0.871 ENST00000216133.5
 CBX7
chromobox homolog 7
chr1_+_183605200 0.699 ENST00000304685.4
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr2_-_217560248 0.682 ENST00000233813.4
 IGFBP5
insulin-like growth factor binding protein 5
chr2_+_85981008 0.626 ENST00000306279.3
 ATOH8
atonal homolog 8 (Drosophila)
chr21_-_35831880 0.625 ENST00000399289.3
ENST00000432085.1
 KCNE1

potassium voltage-gated channel, Isk-related family, member 1

chr4_-_23891693 0.544 ENST00000264867.2
 PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr20_-_4982132 0.524 ENST00000338244.1
ENST00000424750.2
 SLC23A2

solute carrier family 23 (ascorbic acid transporter), member 2

chr9_-_3525968 0.517 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
 RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr1_-_92351769 0.471 ENST00000212355.4
 TGFBR3
transforming growth factor, beta receptor III
chr18_-_53255766 0.461 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
 TCF4




transcription factor 4




chr2_-_213403565 0.458 ENST00000342788.4
ENST00000436443.1
 ERBB4

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

chr17_+_55333876 0.431 ENST00000284073.2
 MSI2
musashi RNA-binding protein 2
chr5_-_124080203 0.393 ENST00000504926.1
 ZNF608
zinc finger protein 608
chr1_+_218519577 0.359 ENST00000366930.4
ENST00000366929.4
 TGFB2

transforming growth factor, beta 2

chr2_+_12857015 0.343 ENST00000155926.4
 TRIB2
tribbles pseudokinase 2
chr2_+_29204161 0.321 ENST00000379558.4
ENST00000403861.2
 FAM179A

family with sequence similarity 179, member A

chr18_+_55711575 0.310 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
 NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.3 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.2 1.2 GO:0070842 aggresome assembly(GO:0070842)
0.4 1.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.5 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 0.5 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.5 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.2 0.5 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.5 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.4 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0042629 mast cell granule(GO:0042629)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.2 GO:0070628 proteasome binding(GO:0070628)
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.2 0.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.1 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling