Motif ID: AGCAGCA

Z-value: 0.554


Mature miRNA associated with seed AGCAGCA:

NamemiRBase Accession
hsa-miR-15a-5p MIMAT0000068
hsa-miR-15b-5p MIMAT0000417
hsa-miR-16-5p MIMAT0000069
hsa-miR-195-5p MIMAT0000461
hsa-miR-424-5p MIMAT0001341
hsa-miR-497-5p MIMAT0002820
hsa-miR-6838-5p MIMAT0027578



Activity profile for motif AGCAGCA.

activity profile for motif AGCAGCA


Sorted Z-values histogram for motif AGCAGCA

Sorted Z-values for motif AGCAGCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_4382917 0.808 ENST00000261254.3
CCND2
cyclin D2
chr9_+_17579084 0.685 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr4_-_111119804 0.432 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr2_-_208030647 0.396 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_-_80056099 0.391 ENST00000306749.2
FASN
fatty acid synthase
chr11_-_119599794 0.357 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr14_-_105420241 0.336 ENST00000557457.1
AHNAK2
AHNAK nucleoprotein 2
chr1_-_22263790 0.321 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr2_-_122042770 0.320 ENST00000263707.5
TFCP2L1
transcription factor CP2-like 1
chr15_+_67358163 0.292 ENST00000327367.4
SMAD3
SMAD family member 3
chr15_+_41245160 0.292 ENST00000444189.2
ENST00000446533.3
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr3_+_47324424 0.282 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr2_-_72375167 0.282 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr2_+_110371905 0.281 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr10_+_88718397 0.259 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr3_-_13921594 0.246 ENST00000285018.4
WNT7A
wingless-type MMTV integration site family, member 7A
chr2_+_26568965 0.244 ENST00000260585.7
ENST00000447170.1
EPT1

ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

chr6_+_43737939 0.243 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr11_-_34379546 0.243 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr19_-_51141196 0.243 ENST00000338916.4
SYT3
synaptotagmin III
chr11_-_65667884 0.238 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr10_-_100995540 0.236 ENST00000370546.1
ENST00000404542.1
HPSE2

heparanase 2

chr7_-_92463210 0.234 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr11_+_113930291 0.230 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr15_-_52821247 0.229 ENST00000399231.3
ENST00000399233.2
MYO5A

myosin VA (heavy chain 12, myoxin)

chr1_-_41131326 0.226 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr6_+_37137939 0.226 ENST00000373509.5
PIM1
pim-1 oncogene
chr11_+_69455855 0.223 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr11_+_72929319 0.222 ENST00000393597.2
ENST00000311131.2
P2RY2

purinergic receptor P2Y, G-protein coupled, 2

chr22_-_42017021 0.219 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr4_+_123747834 0.218 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chrX_-_109561294 0.218 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr2_+_203879568 0.217 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chrX_+_41192595 0.214 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr4_+_128703295 0.213 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr1_+_10271674 0.212 ENST00000377086.1
KIF1B
kinesin family member 1B
chr6_-_75915757 0.212 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr5_+_140207536 0.211 ENST00000529310.1
ENST00000527624.1
PCDHA6

protocadherin alpha 6

chr3_-_48130707 0.211 ENST00000360240.6
ENST00000383737.4
MAP4

microtubule-associated protein 4

chr10_+_99344104 0.208 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr13_-_30169807 0.205 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_-_37217756 0.204 ENST00000440230.1
ENST00000421276.2
ENST00000421307.1
ENST00000354379.4
LRRFIP2



leucine rich repeat (in FLII) interacting protein 2



chr12_+_66217911 0.203 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr17_+_30813576 0.201 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr2_-_165697920 0.198 ENST00000342193.4
ENST00000375458.2
COBLL1

cordon-bleu WH2 repeat protein-like 1

chr9_-_95432536 0.197 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr20_+_3776371 0.195 ENST00000245960.5
CDC25B
cell division cycle 25B
chr6_+_18387570 0.193 ENST00000259939.3
RNF144B
ring finger protein 144B
chr16_+_81348528 0.192 ENST00000568107.2
GAN
gigaxonin
chr6_+_160390102 0.190 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr19_+_45281118 0.189 ENST00000270279.3
ENST00000341505.4
CBLC

Cbl proto-oncogene C, E3 ubiquitin protein ligase

chr1_-_19536744 0.187 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
UBR4



ubiquitin protein ligase E3 component n-recognin 4



chr1_+_2160134 0.186 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr5_-_132299313 0.185 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr1_-_155224751 0.184 ENST00000350210.2
ENST00000368368.3
FAM189B

family with sequence similarity 189, member B

chrX_-_106959631 0.183 ENST00000486554.1
ENST00000372390.4
TSC22D3

TSC22 domain family, member 3

chr11_+_77300669 0.182 ENST00000313578.3
AQP11
aquaporin 11
chr10_+_99400443 0.182 ENST00000370631.3
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr15_+_59063478 0.181 ENST00000559228.1
ENST00000450403.2
FAM63B

family with sequence similarity 63, member B

chr14_+_23775971 0.180 ENST00000250405.5
BCL2L2
BCL2-like 2
chr22_+_31518938 0.180 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr16_-_88851618 0.178 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr5_-_66492562 0.176 ENST00000256447.4
CD180
CD180 molecule
chr1_-_208417620 0.176 ENST00000367033.3
PLXNA2
plexin A2
chr6_+_151561085 0.174 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr16_+_70148230 0.174 ENST00000398122.3
ENST00000568530.1
PDPR

pyruvate dehydrogenase phosphatase regulatory subunit

chr1_-_40157345 0.172 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr11_+_33278811 0.171 ENST00000303296.4
ENST00000379016.3
HIPK3

homeodomain interacting protein kinase 3

chr17_-_4806369 0.170 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr5_-_141704566 0.170 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr17_-_79139817 0.169 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chr15_+_38544476 0.169 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr17_+_7210294 0.167 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chrX_+_135067576 0.166 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
SLC9A6


solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6


chr5_+_74632993 0.164 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr17_-_5487768 0.164 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1


NLR family, pyrin domain containing 1


chr17_-_42441204 0.163 ENST00000293443.7
FAM171A2
family with sequence similarity 171, member A2
chr17_+_28705921 0.163 ENST00000225719.4
CPD
carboxypeptidase D
chr10_+_95256356 0.163 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr2_+_28615669 0.161 ENST00000379619.1
ENST00000264716.4
FOSL2

FOS-like antigen 2

chr19_-_11450249 0.160 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr7_-_98741642 0.159 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr1_-_150979333 0.158 ENST00000312210.5
FAM63A
family with sequence similarity 63, member A
chr22_-_28197486 0.158 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr12_-_108154925 0.157 ENST00000228437.5
PRDM4
PR domain containing 4
chr5_+_140235469 0.157 ENST00000506939.2
ENST00000307360.5
PCDHA10

protocadherin alpha 10

chr17_+_4736627 0.156 ENST00000355280.6
ENST00000347992.7
MINK1

misshapen-like kinase 1

chr1_-_115212696 0.154 ENST00000393276.3
ENST00000393277.1
DENND2C

DENN/MADD domain containing 2C

chr11_+_6411636 0.154 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr19_-_44285401 0.154 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr22_+_45559722 0.153 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50





nucleoporin 50kDa





chr1_-_6321035 0.153 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr5_+_167181917 0.144 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chrX_+_16804544 0.144 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr7_-_143105941 0.143 ENST00000275815.3
EPHA1
EPH receptor A1
chr10_-_102279586 0.141 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B


SEC31 homolog B (S. cerevisiae)


chr20_-_48770174 0.140 ENST00000341698.2
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr3_-_129407535 0.140 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr12_-_112037306 0.139 ENST00000535949.1
ENST00000542287.2
ENST00000377617.3
ENST00000550104.1
ATXN2



ataxin 2



chr15_+_91411810 0.139 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr10_-_61666267 0.137 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chr1_-_23495340 0.135 ENST00000418342.1
LUZP1
leucine zipper protein 1
chr3_+_10206545 0.135 ENST00000256458.4
IRAK2
interleukin-1 receptor-associated kinase 2
chr18_+_10526008 0.134 ENST00000542979.1
ENST00000322897.6
NAPG

N-ethylmaleimide-sensitive factor attachment protein, gamma

chr17_-_73975444 0.133 ENST00000293217.5
ENST00000537812.1
ACOX1

acyl-CoA oxidase 1, palmitoyl

chr2_-_220094294 0.133 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
ATG9A







autophagy related 9A







chr15_+_66679155 0.132 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr1_-_201438282 0.131 ENST00000367311.3
ENST00000367309.1
PHLDA3

pleckstrin homology-like domain, family A, member 3

chr12_+_57943781 0.131 ENST00000455537.2
ENST00000286452.5
KIF5A

kinesin family member 5A

chr20_-_48729670 0.131 ENST00000371657.5
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr8_-_141645645 0.130 ENST00000519980.1
ENST00000220592.5
AGO2

argonaute RISC catalytic component 2

chr3_-_120068143 0.129 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr9_-_99180597 0.129 ENST00000375256.4
ZNF367
zinc finger protein 367
chr1_+_206680879 0.129 ENST00000355294.4
ENST00000367117.3
RASSF5

Ras association (RalGDS/AF-6) domain family member 5

chr11_+_94501497 0.128 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1


angiomotin like 1


chr22_-_37915535 0.128 ENST00000403299.1
CARD10
caspase recruitment domain family, member 10
chr15_+_69706585 0.128 ENST00000559279.1
ENST00000395392.2
KIF23

kinesin family member 23

chr4_+_26585538 0.127 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr11_-_5537920 0.127 ENST00000380184.1
UBQLNL
ubiquilin-like
chr3_+_44379944 0.126 ENST00000396078.3
ENST00000342649.4
TCAIM

T cell activation inhibitor, mitochondrial

chr14_+_53196872 0.126 ENST00000442123.2
ENST00000354586.4
STYX

serine/threonine/tyrosine interacting protein

chrX_-_41782249 0.125 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK




calcium/calmodulin-dependent serine protein kinase (MAGUK family)




chrX_-_77914825 0.125 ENST00000321110.1
ZCCHC5
zinc finger, CCHC domain containing 5
chr3_-_119813264 0.124 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr10_+_103113802 0.124 ENST00000370187.3
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr10_+_105156364 0.124 ENST00000369797.3
PDCD11
programmed cell death 11
chr3_-_48229846 0.122 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A


cell division cycle 25A


chrX_-_30885319 0.122 ENST00000378933.1
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr18_+_12947981 0.121 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr12_-_96794143 0.120 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr1_-_179198702 0.120 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr19_-_40324255 0.120 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr12_-_49449107 0.119 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr1_+_16174280 0.119 ENST00000375759.3
SPEN
spen family transcriptional repressor
chr21_-_44846999 0.119 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr7_+_36429409 0.118 ENST00000265748.2
ANLN
anillin, actin binding protein
chr9_-_131534160 0.115 ENST00000291900.2
ZER1
zyg-11 related, cell cycle regulator
chr2_+_201676256 0.115 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
BZW1


basic leucine zipper and W2 domains 1


chr15_+_41523335 0.115 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr7_-_994302 0.114 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr2_-_172017343 0.114 ENST00000431350.2
ENST00000360843.3
TLK1

tousled-like kinase 1

chr3_+_150126101 0.113 ENST00000361875.3
ENST00000361136.2
TSC22D2

TSC22 domain family, member 2

chr10_-_91403625 0.113 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1


pantothenate kinase 1


chr22_+_24823517 0.113 ENST00000496258.1
ENST00000337539.7
ADORA2A

adenosine A2a receptor

chr2_-_55237484 0.112 ENST00000394609.2
RTN4
reticulon 4
chr10_+_18948311 0.112 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chrX_-_83442915 0.112 ENST00000262752.2
ENST00000543399.1
RPS6KA6

ribosomal protein S6 kinase, 90kDa, polypeptide 6

chr9_-_123639600 0.112 ENST00000373896.3
PHF19
PHD finger protein 19
chr1_-_232697304 0.111 ENST00000366630.1
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr22_+_30279144 0.110 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3




myotubularin related protein 3




chr3_-_160283348 0.110 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr2_-_242801031 0.110 ENST00000334409.5
PDCD1
programmed cell death 1
chr19_+_50270219 0.109 ENST00000354293.5
ENST00000359032.5
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr2_+_26256938 0.108 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr16_-_68269971 0.108 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr11_+_65082289 0.108 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr2_+_170683942 0.108 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr14_-_74485960 0.108 ENST00000556242.1
ENST00000334696.6
ENTPD5

ectonucleoside triphosphate diphosphohydrolase 5

chr9_+_470288 0.107 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr9_-_136857403 0.107 ENST00000406606.3
ENST00000371850.3
VAV2

vav 2 guanine nucleotide exchange factor

chr6_+_11094266 0.107 ENST00000416247.2
SMIM13
small integral membrane protein 13
chr3_-_48471454 0.107 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr11_-_68039364 0.106 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24


chromosome 11 open reading frame 24


chr3_-_122233723 0.105 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1



karyopherin alpha 1 (importin alpha 5)



chr1_-_231560790 0.105 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr6_+_35704855 0.105 ENST00000288065.2
ENST00000373866.3
ARMC12

armadillo repeat containing 12

chr16_-_48644061 0.105 ENST00000262384.3
N4BP1
NEDD4 binding protein 1
chr1_+_46668994 0.104 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr7_-_20256965 0.103 ENST00000400331.5
ENST00000332878.4
MACC1

metastasis associated in colon cancer 1

chr17_+_6899366 0.103 ENST00000251535.6
ALOX12
arachidonate 12-lipoxygenase
chr20_-_48770244 0.103 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189


transmembrane protein 189


chr3_+_126707437 0.103 ENST00000393409.2
ENST00000251772.4
PLXNA1

plexin A1

chr14_-_50698276 0.102 ENST00000216373.5
SOS2
son of sevenless homolog 2 (Drosophila)
chr7_+_128864848 0.101 ENST00000325006.3
ENST00000446544.2
AHCYL2

adenosylhomocysteinase-like 2

chr5_+_95997918 0.101 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
CAST



calpastatin



chr19_+_30302805 0.101 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
CCNE1


cyclin E1


chr17_-_8093471 0.100 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr13_-_21476900 0.100 ENST00000400602.2
ENST00000255305.6
XPO4

exportin 4

chr1_+_12040238 0.099 ENST00000444836.1
ENST00000235329.5
MFN2

mitofusin 2

chr9_+_129622904 0.099 ENST00000319119.4
ZBTB34
zinc finger and BTB domain containing 34
chr14_-_53417732 0.099 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2



fermitin family member 2



chr1_-_109940550 0.099 ENST00000256637.6
SORT1
sortilin 1
chr7_+_1570322 0.098 ENST00000343242.4
MAFK
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr19_+_19496624 0.098 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A


GATA zinc finger domain containing 2A


chr12_+_62654119 0.097 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15


ubiquitin specific peptidase 15


chr18_+_46065393 0.096 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr2_-_109605663 0.096 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chr9_+_35749203 0.095 ENST00000456972.2
ENST00000378078.4
RGP1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr11_+_117049445 0.095 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr12_-_57030115 0.095 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A


bromodomain adjacent to zinc finger domain, 2A


chrX_+_13707235 0.094 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr20_-_1373726 0.094 ENST00000400137.4
FKBP1A
FK506 binding protein 1A, 12kDa
chr5_+_150827143 0.093 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1


solute carrier family 36 (proton/amino acid symporter), member 1


chr15_+_78441663 0.093 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A








isocitrate dehydrogenase 3 (NAD+) alpha








chr8_+_21777159 0.092 ENST00000434536.1
ENST00000252512.9
XPO7

exportin 7

chrX_+_150565653 0.091 ENST00000330374.6
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr20_+_62526467 0.091 ENST00000369911.2
ENST00000360864.4
DNAJC5

DnaJ (Hsp40) homolog, subfamily C, member 5

chr17_+_26662730 0.091 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr8_+_22857048 0.090 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr6_+_34204642 0.090 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.3 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.6 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.2 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0097051 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.1 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.0 GO:1904760 myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.0 GO:0060067 cervix development(GO:0060067)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.4 GO:0035838 growing cell tip(GO:0035838)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031177 S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.1 0.4 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.2 GO:0030305 heparanase activity(GO:0030305)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.0 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.1 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.6 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.8 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 1.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors