ISMARA results: AGUGCAA

Motif ID: AGUGCAA

Z-value: 0.295

Mature miRNA associated with seed AGUGCAA:

Name	miRBase Accession
hsa-miR-130a-3p	MIMAT0000425
hsa-miR-130b-3p	MIMAT0000691
hsa-miR-301a-3p	MIMAT0000688
hsa-miR-301b-3p	MIMAT0004958
hsa-miR-3666	MIMAT0018088
hsa-miR-4295	MIMAT0016844
hsa-miR-454-3p	MIMAT0003885

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Top targets:

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Showing 1 to 20 of 200 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_-_91095099	0.420	ENST00000265431.3	CALB1	calbindin 1, 28kDa
chr4_+_75230853	0.356	ENST00000244869.2	EREG	epiregulin
chr11_-_45687128	0.304	ENST00000308064.2	CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr12_-_25102252	0.263	ENST00000261192.7	BCAT1	branched chain amino-acid transaminase 1, cytosolic
chr5_+_172068232	0.237	ENST00000520919.1 ENST00000522853.1 ENST00000369800.5	NEURL1B	neuralized E3 ubiquitin protein ligase 1B
chr3_-_124774802	0.232	ENST00000311127.4	HEG1	heart development protein with EGF-like domains 1
chr8_+_26435359	0.227	ENST00000311151.5	DPYSL2	dihydropyrimidinase-like 2
chr2_-_122042770	0.221	ENST00000263707.5	TFCP2L1	transcription factor CP2-like 1
chr14_-_75593708	0.216	ENST00000557673.1 ENST00000238616.5	NEK9	NIMA-related kinase 9
chr14_-_34420259	0.214	ENST00000250457.3 ENST00000547327.2	EGLN3	egl-9 family hypoxia-inducible factor 3
chr10_+_35535943	0.209	ENST00000490012.2 ENST00000374706.1 ENST00000493157.2	CCNY	cyclin Y
chr5_-_136834982	0.184	ENST00000510689.1 ENST00000394945.1	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr6_-_99797522	0.181	ENST00000389677.5	FAXC	failed axon connections homolog (Drosophila)
chr1_+_178694300	0.180	ENST00000367635.3	RALGPS2	Ral GEF with PH domain and SH3 binding motif 2
chr11_-_46940074	0.174	ENST00000378623.1 ENST00000534404.1	LRP4	low density lipoprotein receptor-related protein 4
chr2_-_70780770	0.164	ENST00000444975.1 ENST00000445399.1 ENST00000418333.2	TGFA	transforming growth factor, alpha
chr2_-_1748214	0.160	ENST00000433670.1 ENST00000425171.1 ENST00000252804.4	PXDN	peroxidasin homolog (Drosophila)
chrX_-_74376108	0.157	ENST00000339447.4 ENST00000373394.3 ENST00000529949.1 ENST00000534524.1 ENST00000253577.3	ABCB7	ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr10_-_33623564	0.154	ENST00000374875.1 ENST00000374822.4	NRP1	neuropilin 1
chr2_+_219745020	0.152	ENST00000258411.3	WNT10A	wingless-type MMTV integration site family, member 10A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 60 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0042700	luteinizing hormone signaling pathway(GO:0042700)
0.0	0.4	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.0	0.3	GO:0009082	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0	0.3	GO:0060978	angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.1	0.2	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	0.2	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	0.2	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.2	GO:1900248	cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0	0.2	GO:0090625	mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.2	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.2	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.2	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.1	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.0	0.1	GO:1903984	negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:0007356	thorax and anterior abdomen determination(GO:0007356)
0.0	0.1	GO:0072275	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)

Gene overrepresentation in cellular_component category:

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Showing 1 to 16 of 16 entries

Total log-likelihood	Term	Description
0.2	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	GO:0097443	sorting endosome(GO:0097443)
0.2	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.2	GO:0016600	flotillin complex(GO:0016600)
0.1	GO:1990666	PCSK9-LDLR complex(GO:1990666)
0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.1	GO:0031379	RNA-directed RNA polymerase complex(GO:0031379)
0.1	GO:0034681	integrin alpha11-beta1 complex(GO:0034681)
0.1	GO:0005955	calcineurin complex(GO:0005955)
0.1	GO:0070695	FHF complex(GO:0070695)
0.1	GO:0070876	SOSS complex(GO:0070876)
0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.1	GO:0043196	varicosity(GO:0043196)
0.0	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0	GO:0060076	excitatory synapse(GO:0060076)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 28 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.3	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0	0.3	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.2	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.2	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.0	0.1	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.1	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.1	GO:0047389	glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)

Gene overrepresentation in C2:CP category:

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Showing 1 to 2 of 2 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	PID_ERBB_NETWORK_PATHWAY	ErbB receptor signaling network
0.0	0.2	PID_VEGF_VEGFR_PATHWAY	VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 3 of 3 entries

Total log-likelihood	Term	Description
0.4	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.4	REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	Genes involved in Negative regulation of the PI3K/AKT network