Motif ID: ARID5A

Z-value: 1.189


Transcription factors associated with ARID5A:

Gene SymbolEntrez IDGene Name
ARID5A ENSG00000196843.11 ARID5A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARID5Ahg19_v2_chr2_+_97202480_97202499,
hg19_v2_chr2_+_97203082_97203159		0.174.2e-01Click!


Activity profile for motif ARID5A.

activity profile for motif ARID5A


Sorted Z-values histogram for motif ARID5A

Sorted Z-values for motif ARID5A



Network of associatons between targets according to the STRING database.



First level regulatory network of ARID5A

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_43355683 5.980 ENST00000537894.1
 FAM216B
family with sequence similarity 216, member B
chr13_+_43355732 5.832 ENST00000313851.1
 FAM216B
family with sequence similarity 216, member B
chr4_-_177116772 4.688 ENST00000280191.2
 SPATA4
spermatogenesis associated 4
chr9_-_34381511 4.618 ENST00000379124.1
 C9orf24
chromosome 9 open reading frame 24
chr11_+_61976137 4.511 ENST00000244930.4
 SCGB2A1
secretoglobin, family 2A, member 1
chr9_-_34381536 4.439 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
 C9orf24


chromosome 9 open reading frame 24


chr10_-_75118471 3.595 ENST00000340329.3
 TTC18
tetratricopeptide repeat domain 18
chr7_-_16921601 3.283 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
 AGR3


anterior gradient 3


chr20_+_31870927 2.781 ENST00000253354.1
 BPIFB1
BPI fold containing family B, member 1
chr9_-_138391692 2.647 ENST00000429260.2
 C9orf116
chromosome 9 open reading frame 116
chr6_-_33048483 2.394 ENST00000419277.1
 HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr1_+_104159999 2.371 ENST00000414303.2
ENST00000423678.1
 AMY2A

amylase, alpha 2A (pancreatic)

chr11_+_73661364 2.341 ENST00000339764.1
 DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr5_+_140602904 2.275 ENST00000515856.2
ENST00000239449.4
 PCDHB14

protocadherin beta 14

chr15_+_71228826 2.254 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
 LRRC49




leucine rich repeat containing 49




chr6_+_33048222 2.247 ENST00000428835.1
 HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chrX_+_36246735 2.083 ENST00000378653.3
 CXorf30
chromosome X open reading frame 30
chr10_+_127661942 1.957 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
 FANK1


fibronectin type III and ankyrin repeat domains 1


chr1_-_89736434 1.840 ENST00000370459.3
 GBP5
guanylate binding protein 5
chr5_-_41261540 1.761 ENST00000263413.3
 C6
complement component 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.2 GO:0031295 T cell costimulation(GO:0031295)
0.0 5.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 5.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 2.8 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.4 2.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 2.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.5 2.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 2.2 GO:0034389 lipid particle organization(GO:0034389)
0.4 1.8 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 1.8 GO:0032621 interleukin-18 production(GO:0032621)
0.1 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.6 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 1.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.3 1.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 1.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.3 1.0 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 1.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 9.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 2.0 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.2 1.8 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0045178 basal part of cell(GO:0045178)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.8 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 0.6 GO:1990745 EARP complex(GO:1990745)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 3.6 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.8 GO:0070330 aromatase activity(GO:0070330)
0.1 2.5 GO:0002162 dystroglycan binding(GO:0002162)
0.6 2.4 GO:0016160 amylase activity(GO:0016160)
0.0 2.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.0 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.0 GO:0032407 MutSalpha complex binding(GO:0032407)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.9 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.8 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.1 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 8.4 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 3.9 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.8 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 2.4 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 2.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 1.3 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.1 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.1 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.0 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.9 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation