Motif ID: ARID5B
Z-value: 0.959
Transcription factors associated with ARID5B:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| ARID5B | ENSG00000150347.10 | ARID5B |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ARID5B | hg19_v2_chr10_+_63808970_63808990 | 0.16 | 4.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 84 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 5.9 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.2 | 3.8 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 2.7 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.9 | 2.6 | GO:1902299 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.1 | 2.4 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.7 | 2.2 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775) |
| 0.2 | 2.2 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.0 | 2.2 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 2.1 | GO:0060113 | inner ear receptor cell differentiation(GO:0060113) |
| 0.6 | 1.8 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.3 | 1.8 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
| 0.0 | 1.8 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.3 | 1.6 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.1 | 1.6 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.4 | 1.5 | GO:0032416 | negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.1 | 1.5 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 1.5 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) |
| 0.5 | 1.4 | GO:1904580 | regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582) |
| 0.1 | 1.4 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 39 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.5 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.2 | 5.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 3.8 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 3.5 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.9 | 2.6 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.4 | 2.2 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 0.0 | 2.1 | GO:0016605 | PML body(GO:0016605) |
| 0.2 | 1.8 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
| 0.1 | 1.8 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.1 | 1.6 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 1.6 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 1.4 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.2 | 1.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.2 | 0.9 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.1 | 0.9 | GO:0043219 | lateral loop(GO:0043219) |
| 0.0 | 0.9 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.9 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 0.8 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.8 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 60 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 3.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 3.3 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 3.2 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.2 | 2.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.4 | 2.2 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.3 | 2.2 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.1 | 2.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 1.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.2 | 1.5 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.2 | 1.5 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 1.5 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.1 | 1.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 1.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.3 | 1.2 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.0 | 1.0 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 1.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 0.9 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.2 | 0.9 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
Gene overrepresentation in C2:CP category:
Showing 1 to 12 of 12 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.7 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.1 | 3.9 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.0 | 3.3 | PID_BCR_5PATHWAY | BCR signaling pathway |
| 0.0 | 2.0 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.5 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.4 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.9 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.9 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.8 | PID_IL1_PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.6 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.0 | 0.5 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.9 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 3.8 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.1 | 2.6 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.1 | 2.2 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 1.8 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.5 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 1.5 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 1.4 | REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 1.3 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 1.2 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
| 0.1 | 1.0 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.1 | 0.9 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 0.9 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 0.9 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.8 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.7 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.6 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.6 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.6 | REACTOME_DOWNSTREAM_TCR_SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 0.5 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
