Motif ID: AUGGCAC

Z-value: 0.412


Mature miRNA associated with seed AUGGCAC:

NamemiRBase Accession
hsa-miR-183-5p.1 MIMAT0000261



Activity profile for motif AUGGCAC.

activity profile for motif AUGGCAC


Sorted Z-values histogram for motif AUGGCAC

Sorted Z-values for motif AUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGGCAC

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_55333876 0.986 ENST00000284073.2
 MSI2
musashi RNA-binding protein 2
chr9_-_3525968 0.986 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
 RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr6_-_130031358 0.978 ENST00000368149.2
 ARHGAP18
Rho GTPase activating protein 18
chr16_+_57406368 0.902 ENST00000006053.6
ENST00000563383.1
 CX3CL1

chemokine (C-X3-C motif) ligand 1

chrX_+_16964794 0.731 ENST00000357277.3
 REPS2
RALBP1 associated Eps domain containing 2
chr8_+_99076509 0.721 ENST00000318528.3
 C8orf47
chromosome 8 open reading frame 47
chr11_+_45907177 0.680 ENST00000241014.2
 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr12_+_93771659 0.597 ENST00000337179.5
ENST00000415493.2
 NUDT4

nudix (nucleoside diphosphate linked moiety X)-type motif 4

chr18_-_53255766 0.543 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
 TCF4




transcription factor 4




chr19_-_14316980 0.523 ENST00000361434.3
ENST00000340736.6
 LPHN1

latrophilin 1

chr18_+_67956135 0.519 ENST00000397942.3
 SOCS6
suppressor of cytokine signaling 6
chr1_-_169863016 0.510 ENST00000367772.4
ENST00000367771.6
 SCYL3

SCY1-like 3 (S. cerevisiae)

chr15_-_61521495 0.432 ENST00000335670.6
 RORA
RAR-related orphan receptor A
chr16_-_68482440 0.420 ENST00000219334.5
 SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr1_+_180601139 0.406 ENST00000367590.4
ENST00000367589.3
 XPR1

xenotropic and polytropic retrovirus receptor 1

chr17_+_29718642 0.400 ENST00000325874.8
 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr1_-_94374946 0.397 ENST00000370238.3
 GCLM
glutamate-cysteine ligase, modifier subunit
chr15_-_90645679 0.383 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
 IDH2


isocitrate dehydrogenase 2 (NADP+), mitochondrial


chr4_-_39640700 0.376 ENST00000295958.5
 SMIM14
small integral membrane protein 14
chr6_-_52926539 0.357 ENST00000350082.5
ENST00000356971.3
 ICK

intestinal cell (MAK-like) kinase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.0 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.3 0.9 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.4 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.3 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.1 0.8 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.6 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters