Motif ID: BARX1

Z-value: 0.729


Transcription factors associated with BARX1:

Gene SymbolEntrez IDGene Name
BARX1 ENSG00000131668.9 BARX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BARX1hg19_v2_chr9_-_96717654_96717666-0.145.3e-01Click!


Activity profile for motif BARX1.

activity profile for motif BARX1


Sorted Z-values histogram for motif BARX1

Sorted Z-values for motif BARX1



Network of associatons between targets according to the STRING database.



First level regulatory network of BARX1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_16921601 1.603 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
 AGR3


anterior gradient 3


chr12_+_9980113 1.555 ENST00000537723.1
 KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr15_-_56757329 1.551 ENST00000260453.3
 MNS1
meiosis-specific nuclear structural 1
chr11_+_61976137 1.203 ENST00000244930.4
 SCGB2A1
secretoglobin, family 2A, member 1
chr6_+_32407619 1.191 ENST00000395388.2
ENST00000374982.5
 HLA-DRA

major histocompatibility complex, class II, DR alpha

chr4_+_52917451 0.971 ENST00000295213.4
ENST00000419395.2
 SPATA18

spermatogenesis associated 18

chr12_+_20963632 0.935 ENST00000540853.1
ENST00000261196.2
 SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr12_-_71551652 0.855 ENST00000546561.1
 TSPAN8
tetraspanin 8
chr6_+_163148161 0.842 ENST00000337019.3
ENST00000366889.2
 PACRG

PARK2 co-regulated

chr12_+_9980069 0.830 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
 KLRF1


killer cell lectin-like receptor subfamily F, member 1


chr12_+_20963647 0.816 ENST00000381545.3
 SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr5_+_121465207 0.769 ENST00000296600.4
 ZNF474
zinc finger protein 474
chr2_+_228736335 0.764 ENST00000440997.1
ENST00000545118.1
 DAW1

dynein assembly factor with WDR repeat domains 1

chr6_+_131958436 0.734 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
 ENPP3



ectonucleotide pyrophosphatase/phosphodiesterase 3



chr12_-_71551868 0.732 ENST00000247829.3
 TSPAN8
tetraspanin 8
chr15_+_71228826 0.723 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
 LRRC49




leucine rich repeat containing 49




chr10_+_51549498 0.666 ENST00000358559.2
ENST00000298239.6
 MSMB

microseminoprotein, beta-

chr6_-_150212029 0.662 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
 RAET1E


retinoic acid early transcript 1E


chr21_-_35884573 0.624 ENST00000399286.2
 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr4_-_70518941 0.614 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
 UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.7 GO:0070986 left/right axis specification(GO:0070986)
0.0 1.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.3 1.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 1.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 1.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 1.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.7 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.6 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.5 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.5 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.5 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.5 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0036126 sperm flagellum(GO:0036126)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 1.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.5 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.5 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0098576 lumenal side of membrane(GO:0098576)
0.1 0.4 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 2.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.0 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 0.8 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 0.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.6 GO:0031433 telethonin binding(GO:0031433)
0.1 0.5 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.4 GO:0035663 Toll-like receptor 2 binding(GO:0035663)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID_IL5_PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation