Motif ID: BATF

Z-value: 1.262


Transcription factors associated with BATF:

Gene SymbolEntrez IDGene Name
BATF ENSG00000156127.6 BATF

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BATFhg19_v2_chr14_+_75988768_75988826-0.135.6e-01Click!


Activity profile for motif BATF.

activity profile for motif BATF


Sorted Z-values histogram for motif BATF

Sorted Z-values for motif BATF



Network of associatons between targets according to the STRING database.



First level regulatory network of BATF

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_51504411 5.351 ENST00000593490.1
KLK8
kallikrein-related peptidase 8
chr1_-_153113927 4.417 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr18_+_21452964 4.372 ENST00000587184.1
LAMA3
laminin, alpha 3
chr1_+_150480576 4.246 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr9_+_33795533 4.134 ENST00000379405.3
PRSS3
protease, serine, 3
chr2_-_113594279 3.907 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr1_-_113478603 3.700 ENST00000443580.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr18_+_21452804 3.691 ENST00000269217.6
LAMA3
laminin, alpha 3
chr19_-_51487071 3.489 ENST00000391807.1
ENST00000593904.1
KLK7

kallikrein-related peptidase 7

chr1_+_150480551 3.431 ENST00000369049.4
ENST00000369047.4
ECM1

extracellular matrix protein 1

chr1_-_153521597 3.422 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr17_-_39769005 3.043 ENST00000301653.4
ENST00000593067.1
KRT16

keratin 16

chr12_+_13349650 2.938 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr1_-_153029980 2.855 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr1_-_153348067 2.731 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr12_-_52845910 2.683 ENST00000252252.3
KRT6B
keratin 6B
chr1_-_153521714 2.669 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr19_-_36019123 2.458 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr12_+_8975061 2.237 ENST00000299698.7
A2ML1
alpha-2-macroglobulin-like 1
chr9_+_105757590 2.136 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 550 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 14.7 GO:0018149 peptide cross-linking(GO:0018149)
0.4 12.2 GO:2000404 regulation of T cell migration(GO:2000404)
0.4 12.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 5.5 GO:0002377 immunoglobulin production(GO:0002377)
0.8 5.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 4.6 GO:0007398 ectoderm development(GO:0007398)
0.2 4.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 4.2 GO:0070268 cornification(GO:0070268)
1.3 3.9 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.0 3.9 GO:0006218 uridine catabolic process(GO:0006218)
1.2 3.7 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.6 3.5 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 3.5 GO:0051546 keratinocyte migration(GO:0051546)
0.4 3.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 3.2 GO:0032060 bleb assembly(GO:0032060)
0.6 3.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 2.9 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.7 2.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 2.6 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.4 2.5 GO:0007296 vitellogenesis(GO:0007296)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 184 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 19.6 GO:0001533 cornified envelope(GO:0001533)
1.1 8.4 GO:0005610 laminin-5 complex(GO:0005610)
0.4 7.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 7.3 GO:0005882 intermediate filament(GO:0005882)
0.1 5.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 5.0 GO:0005925 focal adhesion(GO:0005925)
0.1 4.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 3.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 3.6 GO:0097342 ripoptosome(GO:0097342)
0.5 3.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 3.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.0 GO:0030175 filopodium(GO:0030175)
0.0 2.9 GO:0030027 lamellipodium(GO:0030027)
0.1 2.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.5 GO:0097228 sperm principal piece(GO:0097228)
0.4 2.2 GO:0097149 centralspindlin complex(GO:0097149)
0.1 2.2 GO:0008091 spectrin(GO:0008091)
0.7 2.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.2 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 348 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 23.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 14.5 GO:0005198 structural molecule activity(GO:0005198)
0.1 10.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.9 7.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.3 6.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 5.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 4.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8 3.9 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 3.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
1.2 3.7 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 3.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 3.6 GO:0043022 ribosome binding(GO:0043022)
0.0 3.6 GO:0005518 collagen binding(GO:0005518)
0.0 3.5 GO:0044325 ion channel binding(GO:0044325)
0.1 3.2 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.8 GO:0005123 death receptor binding(GO:0005123)
0.1 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 2.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 2.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.5 GO:0001972 retinoic acid binding(GO:0001972)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 12.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5 11.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 6.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 5.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 5.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 3.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 2.8 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.9 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.7 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 1.2 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.1 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 1.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.3 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.1 7.6 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 5.3 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 4.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.2 4.0 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.2 3.7 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.7 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 3.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.8 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.6 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.0 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.8 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 1.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.7 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts