Motif ID: BPTF
Z-value: 1.672
Transcription factors associated with BPTF:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| BPTF | ENSG00000171634.12 | BPTF |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BPTF | hg19_v2_chr17_+_65821780_65821826 | 0.37 | 7.4e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 435 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.3 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.3 | 8.5 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.1 | 7.6 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.2 | 6.6 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.9 | 4.5 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.0 | 4.3 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 3.6 | GO:0006413 | translational initiation(GO:0006413) |
| 0.2 | 3.5 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.2 | 3.1 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.2 | 3.0 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.4 | 2.5 | GO:0021523 | somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491) |
| 0.4 | 2.2 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.1 | 2.1 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 2.1 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.2 | 2.0 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 2.0 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.0 | 2.0 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.1 | 1.9 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.1 | 1.9 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.0 | 1.9 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 187 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 16.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 12.1 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 4.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 4.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 3.7 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 3.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.2 | 3.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 2.8 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 0.0 | 2.8 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 2.6 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 2.6 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 2.3 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 2.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 2.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.8 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.6 | 1.7 | GO:0001534 | radial spoke(GO:0001534) |
| 0.1 | 1.7 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.1 | 1.7 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 1.6 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.1 | 1.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 293 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 19.8 | GO:0019843 | rRNA binding(GO:0019843) |
| 1.0 | 6.7 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.4 | 4.6 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.2 | 4.5 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 4.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 3.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 2.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.4 | 2.6 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.4 | 2.5 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.0 | 2.2 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.5 | 2.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.5 | 2.0 | GO:0016160 | amylase activity(GO:0016160) |
| 0.1 | 2.0 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.0 | 2.0 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.3 | 1.9 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.1 | 1.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 1.9 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.0 | 1.9 | GO:0042393 | histone binding(GO:0042393) |
| 0.3 | 1.8 | GO:0047685 | amine sulfotransferase activity(GO:0047685) |
| 0.0 | 1.8 | GO:0001047 | core promoter binding(GO:0001047) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 38 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.1 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 3.3 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.1 | 2.8 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 2.5 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 2.1 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
| 0.1 | 2.0 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 1.5 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.4 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.2 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.0 | 1.2 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 1.2 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.1 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.1 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.0 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 0.9 | PID_IL1_PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.9 | PID_INSULIN_PATHWAY | Insulin Pathway |
| 0.0 | 0.8 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.7 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.6 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.0 | 0.6 | PID_P73PATHWAY | p73 transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 64 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 11.7 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.4 | 10.4 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 4.8 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.4 | 3.5 | REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 3.4 | REACTOME_RNA_POL_III_TRANSCRIPTION | Genes involved in RNA Polymerase III Transcription |
| 0.0 | 3.0 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 2.7 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 2.6 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 2.1 | REACTOME_XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 2.1 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.9 | REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.0 | 1.7 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.6 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 1.6 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.4 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.2 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.1 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 1.0 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 1.0 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 1.0 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
