Motif ID: CACAGUG

Z-value: 0.448


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128-3p MIMAT0000424
hsa-miR-216a-3p MIMAT0022844
hsa-miR-3681-3p MIMAT0018109



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_7921090 1.281 ENST00000378789.3
 HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr20_-_50419055 0.623 ENST00000217086.4
 SALL4
spalt-like transcription factor 4
chr4_-_107957454 0.565 ENST00000285311.3
 DKK2
dickkopf WNT signaling pathway inhibitor 2
chr16_+_66878814 0.540 ENST00000394069.3
 CA7
carbonic anhydrase VII
chr11_-_123525289 0.527 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
 SCN3B


sodium channel, voltage-gated, type III, beta subunit


chr4_+_5053162 0.395 ENST00000282908.5
 STK32B
serine/threonine kinase 32B
chrX_+_78426469 0.377 ENST00000276077.1
 GPR174
G protein-coupled receptor 174
chr20_-_41818373 0.363 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
 PTPRT



protein tyrosine phosphatase, receptor type, T



chr15_+_29131103 0.320 ENST00000558402.1
ENST00000558330.1
 APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2

chr15_-_82641706 0.315 ENST00000439287.4
 GOLGA6L10
golgin A6 family-like 10
chr17_-_50237343 0.314 ENST00000575181.1
ENST00000570565.1
 CA10

carbonic anhydrase X

chr15_-_82939157 0.306 ENST00000559949.1
 RP13-996F3.5
golgin A6 family-like 18
chr22_-_37099555 0.297 ENST00000300105.6
 CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chrX_+_64708615 0.296 ENST00000338957.4
ENST00000423889.3
 ZC3H12B

zinc finger CCCH-type containing 12B

chr8_+_1922024 0.290 ENST00000320248.3
 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr15_-_83018198 0.281 ENST00000557886.1
 RP13-996F3.4
golgin A6 family-like 19
chr5_-_157002775 0.278 ENST00000257527.4
 ADAM19
ADAM metallopeptidase domain 19
chr16_+_77822427 0.273 ENST00000302536.2
 VAT1L
vesicle amine transport 1-like
chr11_-_30038490 0.267 ENST00000328224.6
 KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr1_+_215256467 0.261 ENST00000391894.2
ENST00000444842.2
 KCNK2

potassium channel, subfamily K, member 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.5 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.2 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0008355 olfactory learning(GO:0008355)
0.1 0.2 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG