Motif ID: CCCUGAG

Z-value: 0.592


Mature miRNA associated with seed CCCUGAG:

NamemiRBase Accession
hsa-miR-125a-5p MIMAT0000443
hsa-miR-125b-5p MIMAT0000423
hsa-miR-4319 MIMAT0016870



Activity profile for motif CCCUGAG.

activity profile for motif CCCUGAG


Sorted Z-values histogram for motif CCCUGAG

Sorted Z-values for motif CCCUGAG



Network of associatons between targets according to the STRING database.



First level regulatory network of CCCUGAG

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_61276214 2.863 ENST00000378075.2
 LRRC10B
leucine rich repeat containing 10B
chr7_-_131241361 2.555 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
 PODXL



podocalyxin-like



chr15_-_90358048 1.850 ENST00000300060.6
ENST00000560137.1
 ANPEP

alanyl (membrane) aminopeptidase

chr6_-_24911195 1.800 ENST00000259698.4
 FAM65B
family with sequence similarity 65, member B
chr5_-_100238956 1.691 ENST00000231461.5
 ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr13_-_29292956 1.390 ENST00000266943.6
 SLC46A3
solute carrier family 46, member 3
chr3_+_58223228 1.381 ENST00000478253.1
ENST00000295962.4
 ABHD6

abhydrolase domain containing 6

chr22_-_39548627 1.328 ENST00000216133.5
 CBX7
chromobox homolog 7
chr3_+_186648274 1.303 ENST00000169298.3
 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr4_+_75858290 1.290 ENST00000513238.1
 PARM1
prostate androgen-regulated mucin-like protein 1
chr6_+_17281573 1.284 ENST00000379052.5
 RBM24
RNA binding motif protein 24
chr20_-_33460621 1.244 ENST00000427420.1
ENST00000336431.5
 GGT7

gamma-glutamyltransferase 7

chr9_-_3525968 1.084 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
 RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr12_-_63328817 1.029 ENST00000228705.6
 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr13_-_86373536 1.002 ENST00000400286.2
 SLITRK6
SLIT and NTRK-like family, member 6
chr14_+_56585048 0.966 ENST00000267460.4
 PELI2
pellino E3 ubiquitin protein ligase family member 2
chr1_+_151483855 0.938 ENST00000427934.2
ENST00000271636.7
 CGN

cingulin

chr7_-_120498357 0.867 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
 TSPAN12


tetraspanin 12


chrX_-_132549506 0.847 ENST00000370828.3
 GPC4
glypican 4
chr8_+_76452097 0.846 ENST00000396423.2
 HNF4G
hepatocyte nuclear factor 4, gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 1.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.7 GO:0043171 peptide catabolic process(GO:0043171)
0.2 1.6 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.1 1.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 1.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4 1.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 1.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 1.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.2 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 0.9 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.8 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.8 GO:0002467 germinal center formation(GO:0002467)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.2 0.7 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.7 GO:0050915 sensory perception of sour taste(GO:0050915)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0032009 early phagosome(GO:0032009)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.5 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.3 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0060187 cell pole(GO:0060187)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 1.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.6 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.9 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.5 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation