Motif ID: CCUUCAU

Z-value: 0.549


Mature miRNA associated with seed CCUUCAU:

NamemiRBase Accession
hsa-miR-205-5p MIMAT0000266



Activity profile for motif CCUUCAU.

activity profile for motif CCUUCAU


Sorted Z-values histogram for motif CCUUCAU

Sorted Z-values for motif CCUUCAU



Network of associatons between targets according to the STRING database.



First level regulatory network of CCUUCAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_55333876 1.407 ENST00000284073.2
 MSI2
musashi RNA-binding protein 2
chr13_+_43355683 1.193 ENST00000537894.1
 FAM216B
family with sequence similarity 216, member B
chr2_-_213403565 1.141 ENST00000342788.4
ENST00000436443.1
 ERBB4

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

chr3_-_114790179 0.914 ENST00000462705.1
 ZBTB20
zinc finger and BTB domain containing 20
chr1_-_217262969 0.843 ENST00000361525.3
 ESRRG
estrogen-related receptor gamma
chr16_+_69599861 0.799 ENST00000354436.2
 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr5_+_167718604 0.683 ENST00000265293.4
 WWC1
WW and C2 domain containing 1
chr6_-_116381918 0.658 ENST00000606080.1
 FRK
fyn-related kinase
chrX_-_112084043 0.654 ENST00000304758.1
 AMOT
angiomotin
chr2_+_228735763 0.609 ENST00000373666.2
 DAW1
dynein assembly factor with WDR repeat domains 1
chr2_+_29204161 0.591 ENST00000379558.4
ENST00000403861.2
 FAM179A

family with sequence similarity 179, member A

chr12_+_56473628 0.582 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
 ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr15_-_61521495 0.514 ENST00000335670.6
 RORA
RAR-related orphan receptor A
chr13_-_61989655 0.508 ENST00000409204.4
 PCDH20
protocadherin 20
chr16_-_87525651 0.474 ENST00000268616.4
 ZCCHC14
zinc finger, CCHC domain containing 14
chr4_-_11431389 0.470 ENST00000002596.5
 HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr4_-_83719983 0.436 ENST00000319540.4
 SCD5
stearoyl-CoA desaturase 5
chr11_-_115375107 0.430 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1





cell adhesion molecule 1





chr4_+_77356248 0.413 ENST00000296043.6
 SHROOM3
shroom family member 3
chr7_-_79082867 0.413 ENST00000419488.1
ENST00000354212.4
 MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 1.1 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.6 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.4 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499) negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.4 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.3 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.3 GO:2001038 regulation of cellular response to drug(GO:2001038)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.4 GO:0044753 amphisome(GO:0044753)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.7 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.3 PID_IL5_PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME_SHC_RELATED_EVENTS Genes involved in SHC-related events