Motif ID: CDX2

Z-value: 0.426


Transcription factors associated with CDX2:

Gene SymbolEntrez IDGene Name
CDX2 ENSG00000165556.9 CDX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CDX2hg19_v2_chr13_-_28545276_285452760.145.1e-01Click!


Activity profile for motif CDX2.

activity profile for motif CDX2


Sorted Z-values histogram for motif CDX2

Sorted Z-values for motif CDX2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_71551868 0.853 ENST00000247829.3
 TSPAN8
tetraspanin 8
chr12_-_71551652 0.814 ENST00000546561.1
 TSPAN8
tetraspanin 8
chr1_-_160231451 0.751 ENST00000495887.1
 DCAF8
DDB1 and CUL4 associated factor 8
chr10_-_129691195 0.655 ENST00000368671.3
 CLRN3
clarin 3
chr6_+_32812568 0.541 ENST00000414474.1
 PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr16_+_71560154 0.514 ENST00000539698.3
 CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr16_+_71560023 0.498 ENST00000572450.1
 CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr11_+_71900703 0.428 ENST00000393681.2
 FOLR1
folate receptor 1 (adult)
chr11_+_71900572 0.412 ENST00000312293.4
 FOLR1
folate receptor 1 (adult)
chr7_+_80275621 0.404 ENST00000426978.1
ENST00000432207.1
 CD36

CD36 molecule (thrombospondin receptor)

chr7_+_80275752 0.400 ENST00000419819.2
 CD36
CD36 molecule (thrombospondin receptor)
chr11_+_27062860 0.384 ENST00000528583.1
 BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_+_80275953 0.382 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
 CD36


CD36 molecule (thrombospondin receptor)


chr3_+_140981456 0.380 ENST00000504264.1
 ACPL2
acid phosphatase-like 2
chr3_+_149191723 0.345 ENST00000305354.4
 TM4SF4
transmembrane 4 L six family member 4
chr13_-_62001982 0.334 ENST00000409186.1
 PCDH20
protocadherin 20
chrX_-_15619076 0.290 ENST00000252519.3
 ACE2
angiotensin I converting enzyme 2
chr11_-_3400442 0.288 ENST00000429541.2
ENST00000532539.1
 ZNF195

zinc finger protein 195

chr11_-_3400330 0.288 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
 ZNF195











zinc finger protein 195











chr6_-_87804815 0.261 ENST00000369582.2
 CGA
glycoprotein hormones, alpha polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 1.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.0 GO:0006477 protein sulfation(GO:0006477)
0.3 0.8 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 0.8 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones