Motif ID: CENPB

Z-value: 0.792


Transcription factors associated with CENPB:

Gene SymbolEntrez IDGene Name
CENPB ENSG00000125817.7 CENPB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CENPBhg19_v2_chr20_-_3767324_37674430.058.3e-01Click!


Activity profile for motif CENPB.

activity profile for motif CENPB


Sorted Z-values histogram for motif CENPB

Sorted Z-values for motif CENPB



Network of associatons between targets according to the STRING database.



First level regulatory network of CENPB

PNG image of the network

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Top targets:


Showing 1 to 20 of 141 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_25348007 6.197 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
 CASC1






cancer susceptibility candidate 1






chr11_+_71791849 3.118 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
 LRTOMT




leucine rich transmembrane and O-methyltransferase domain containing




chrY_+_2709527 3.061 ENST00000250784.8
 RPS4Y1
ribosomal protein S4, Y-linked 1
chrY_+_2709906 2.937 ENST00000430575.1
 RPS4Y1
ribosomal protein S4, Y-linked 1
chr11_+_71791693 2.707 ENST00000289488.2
ENST00000447974.1
 LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

chr11_+_71791803 2.642 ENST00000539271.1
 LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr11_+_71791359 2.637 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
 LRTOMT



leucine rich transmembrane and O-methyltransferase domain containing



chr13_+_24144796 2.236 ENST00000403372.2
 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr13_+_24144509 2.221 ENST00000248484.4
 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr13_+_24153488 2.152 ENST00000382258.4
ENST00000382263.3
 TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr22_-_42765174 1.641 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
 Z83851.1


Z83851.1


chr15_-_48470544 1.583 ENST00000267836.6
 MYEF2
myelin expression factor 2
chr6_-_28411241 1.557 ENST00000289788.4
 ZSCAN23
zinc finger and SCAN domain containing 23
chr20_-_55841398 1.455 ENST00000395864.3
 BMP7
bone morphogenetic protein 7
chr2_-_241500447 1.331 ENST00000536462.1
ENST00000405002.1
ENST00000441168.1
ENST00000403283.1
 ANKMY1



ankyrin repeat and MYND domain containing 1



chr17_-_6947225 1.324 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
 SLC16A11


solute carrier family 16, member 11


chr2_+_11295498 1.231 ENST00000295083.3
ENST00000441908.2
 PQLC3

PQ loop repeat containing 3

chr6_+_27356497 0.994 ENST00000244576.4
 ZNF391
zinc finger protein 391
chr6_-_39197226 0.973 ENST00000359534.3
 KCNK5
potassium channel, subfamily K, member 5
chr12_-_40499661 0.955 ENST00000280871.4
 SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 11.1 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 6.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 5.3 GO:0001942 hair follicle development(GO:0001942)
0.0 2.3 GO:0014902 myotube differentiation(GO:0014902)
0.5 2.2 GO:0072134 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069)
0.1 1.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 1.0 GO:0015798 myo-inositol transport(GO:0015798)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 0.9 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.9 GO:0007220 Notch receptor processing(GO:0007220)
0.2 0.8 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.8 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 0.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.5 GO:0007379 segment specification(GO:0007379)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0005844 polysome(GO:0005844)
0.0 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.6 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 11.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 6.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 6.0 GO:0019843 rRNA binding(GO:0019843)
0.2 2.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.4 1.3 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 1.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.8 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.2 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 2.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.3 0.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA