Motif ID: CPEB1
Z-value: 0.790
Transcription factors associated with CPEB1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
CPEB1 | ENSG00000214575.5 | CPEB1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
CPEB1 | hg19_v2_chr15_-_83240507_83240539 | -0.14 | 5.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.3 | 1.0 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.3 | 0.9 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
0.3 | 0.9 | GO:0060585 | regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
0.2 | 0.6 | GO:0044771 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
0.1 | 0.4 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.1 | 0.4 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
0.1 | 0.4 | GO:0080154 | regulation of fertilization(GO:0080154) |
0.1 | 0.9 | GO:0097338 | response to clozapine(GO:0097338) |
0.1 | 1.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.1 | 0.3 | GO:0006427 | histidyl-tRNA aminoacylation(GO:0006427) |
0.1 | 0.3 | GO:0090425 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
0.1 | 0.3 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
0.1 | 0.8 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
0.1 | 0.8 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
0.1 | 0.5 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.1 | 0.6 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
0.1 | 0.4 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
0.1 | 0.4 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
0.1 | 0.2 | GO:0014034 | neural crest cell fate commitment(GO:0014034) |
0.1 | 0.7 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
0.1 | 0.8 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
0.1 | 0.1 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
0.1 | 1.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
0.1 | 0.3 | GO:0036269 | swimming behavior(GO:0036269) |
0.1 | 0.6 | GO:2000609 | regulation of thyroid hormone generation(GO:2000609) |
0.1 | 1.3 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 0.8 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
0.1 | 0.6 | GO:0015705 | iodide transport(GO:0015705) |
0.1 | 0.8 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
0.1 | 1.6 | GO:0071481 | cellular response to X-ray(GO:0071481) |
0.1 | 0.2 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
0.1 | 0.5 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
0.1 | 0.2 | GO:0072092 | ureteric bud invasion(GO:0072092) |
0.1 | 1.0 | GO:0016102 | retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) |
0.1 | 0.2 | GO:0044179 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
0.1 | 0.5 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.8 | GO:0035878 | nail development(GO:0035878) |
0.1 | 0.2 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
0.1 | 0.2 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.1 | 0.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.1 | 0.2 | GO:0046671 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
0.1 | 0.2 | GO:0035905 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
0.1 | 0.2 | GO:0048880 | sensory system development(GO:0048880) |
0.0 | 0.1 | GO:1901207 | regulation of heart looping(GO:1901207) |
0.0 | 0.1 | GO:0001812 | positive regulation of type I hypersensitivity(GO:0001812) |
0.0 | 0.3 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
0.0 | 0.2 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
0.0 | 0.2 | GO:1990637 | response to prolactin(GO:1990637) |
0.0 | 0.3 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
0.0 | 0.1 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
0.0 | 0.3 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
0.0 | 0.2 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.0 | 0.4 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
0.0 | 0.2 | GO:0048867 | ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867) |
0.0 | 0.3 | GO:0046098 | guanine metabolic process(GO:0046098) |
0.0 | 0.3 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
0.0 | 0.4 | GO:0034650 | aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342) cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651) |
0.0 | 0.3 | GO:0021615 | rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615) |
0.0 | 0.6 | GO:0009629 | response to gravity(GO:0009629) |
0.0 | 0.8 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 0.3 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.0 | 0.1 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
0.0 | 0.2 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
0.0 | 0.1 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
0.0 | 0.5 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 1.0 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
0.0 | 0.1 | GO:0042116 | macrophage activation(GO:0042116) |
0.0 | 0.2 | GO:0003051 | angiotensin-mediated drinking behavior(GO:0003051) |
0.0 | 0.3 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.0 | 0.3 | GO:1904783 | positive regulation of NMDA glutamate receptor activity(GO:1904783) |
0.0 | 0.1 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
0.0 | 0.1 | GO:1903936 | response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936) |
0.0 | 0.1 | GO:0001757 | somite specification(GO:0001757) sclerotome development(GO:0061056) |
0.0 | 0.1 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.1 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
0.0 | 3.8 | GO:0070268 | cornification(GO:0070268) |
0.0 | 0.1 | GO:0003335 | corneocyte development(GO:0003335) |
0.0 | 0.2 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.0 | 0.2 | GO:0098704 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
0.0 | 0.2 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.1 | GO:2000229 | pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) |
0.0 | 0.1 | GO:1904717 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
0.0 | 0.2 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.0 | 0.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.7 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 0.1 | GO:1900158 | positive regulation of osteoclast proliferation(GO:0090290) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
0.0 | 0.3 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
0.0 | 0.1 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
0.0 | 0.1 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.0 | 0.2 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.0 | 0.3 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.0 | 1.8 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.3 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
0.0 | 0.6 | GO:0048665 | neuron fate specification(GO:0048665) |
0.0 | 0.3 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.2 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
0.0 | 0.2 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
0.0 | 0.2 | GO:0030091 | protein repair(GO:0030091) |
0.0 | 0.2 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
0.0 | 0.7 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
0.0 | 0.1 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.0 | 0.1 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.0 | 0.1 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
0.0 | 1.0 | GO:0051602 | response to electrical stimulus(GO:0051602) |
0.0 | 0.1 | GO:0072014 | proximal tubule development(GO:0072014) |
0.0 | 0.1 | GO:1902227 | negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978) |
0.0 | 0.1 | GO:0044245 | polysaccharide digestion(GO:0044245) |
0.0 | 0.1 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 0.1 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
0.0 | 0.2 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.0 | 0.1 | GO:1990737 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
0.0 | 0.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.2 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
0.0 | 0.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
0.0 | 0.0 | GO:0033024 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) |
0.0 | 0.0 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.0 | 0.3 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.0 | 0.2 | GO:0003183 | mitral valve morphogenesis(GO:0003183) |
0.0 | 0.1 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
0.0 | 0.0 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
0.0 | 0.8 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
0.0 | 0.3 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.0 | 0.8 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.1 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
0.0 | 0.4 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.0 | 0.2 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
0.0 | 0.4 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.0 | 0.9 | GO:0014047 | glutamate secretion(GO:0014047) |
0.0 | 0.7 | GO:0097435 | fibril organization(GO:0097435) |
0.0 | 0.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.3 | GO:0000732 | strand displacement(GO:0000732) |
0.0 | 0.1 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
0.0 | 0.1 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
0.0 | 0.2 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
0.0 | 0.1 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
0.0 | 0.4 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
0.0 | 0.1 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.0 | 0.3 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
0.0 | 0.1 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 0.1 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
0.0 | 0.5 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.0 | 0.3 | GO:0030199 | collagen fibril organization(GO:0030199) |
0.0 | 0.1 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 0.2 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.1 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
0.0 | 0.1 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
0.0 | 0.2 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
0.0 | 0.1 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
0.0 | 0.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.1 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
0.0 | 0.1 | GO:0039663 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.3 | 0.8 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
0.3 | 1.5 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.2 | 0.9 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.2 | 0.5 | GO:0034676 | integrin alpha6-beta4 complex(GO:0034676) |
0.1 | 1.3 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
0.1 | 0.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 1.8 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.1 | 0.6 | GO:0035976 | AP1 complex(GO:0035976) |
0.1 | 0.5 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
0.1 | 0.5 | GO:0002177 | manchette(GO:0002177) |
0.1 | 1.0 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.1 | 0.2 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.1 | 0.7 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.0 | 0.5 | GO:0043219 | lateral loop(GO:0043219) |
0.0 | 0.6 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.0 | 0.4 | GO:0005955 | calcineurin complex(GO:0005955) |
0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 1.0 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 1.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.1 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
0.0 | 0.6 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 2.2 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 1.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 0.3 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 0.1 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.0 | 0.3 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 0.1 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.0 | 0.1 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.0 | 1.9 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.0 | 1.2 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.2 | GO:0072687 | meiotic spindle(GO:0072687) |
0.0 | 0.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 0.1 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.2 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.2 | GO:0005915 | zonula adherens(GO:0005915) |
0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.0 | 0.1 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
0.0 | 0.3 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.2 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 0.4 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.0 | 0.1 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.0 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.2 | 1.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 0.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.1 | 0.4 | GO:0004507 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
0.1 | 0.8 | GO:0042835 | BRE binding(GO:0042835) |
0.1 | 0.6 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.1 | 0.4 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.1 | 0.4 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
0.1 | 0.7 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.1 | 0.3 | GO:0004821 | histidine-tRNA ligase activity(GO:0004821) |
0.1 | 0.5 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.1 | 0.4 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
0.1 | 1.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.1 | 0.4 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
0.1 | 0.3 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.1 | 0.5 | GO:1990254 | keratin filament binding(GO:1990254) |
0.1 | 0.5 | GO:0050816 | phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816) |
0.1 | 1.0 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.5 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 0.2 | GO:0070698 | type I activin receptor binding(GO:0070698) |
0.1 | 0.7 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
0.1 | 0.5 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 0.5 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 0.3 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.1 | 0.2 | GO:0031531 | thyrotropin-releasing hormone receptor binding(GO:0031531) |
0.0 | 1.0 | GO:0019841 | retinol binding(GO:0019841) |
0.0 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.7 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.0 | 0.2 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.0 | 0.2 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.0 | 0.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
0.0 | 0.8 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.4 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.0 | 0.5 | GO:0038132 | neuregulin binding(GO:0038132) |
0.0 | 0.2 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
0.0 | 1.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
0.0 | 0.9 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.4 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 1.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.0 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.0 | 0.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 0.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
0.0 | 0.3 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.2 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 1.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.2 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
0.0 | 0.2 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
0.0 | 0.2 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
0.0 | 0.1 | GO:0016936 | galactoside binding(GO:0016936) |
0.0 | 0.1 | GO:0050253 | retinyl-palmitate esterase activity(GO:0050253) |
0.0 | 0.1 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
0.0 | 0.6 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.1 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
0.0 | 0.1 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
0.0 | 0.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 1.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.3 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.4 | GO:0030275 | LRR domain binding(GO:0030275) |
0.0 | 0.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.1 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.0 | 0.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.1 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.0 | 0.2 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.0 | 0.1 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.0 | 0.2 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.7 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
0.0 | 1.1 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.0 | 2.0 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 1.8 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 0.5 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.7 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 1.1 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 0.8 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.5 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 0.7 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.5 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 0.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 1.5 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 0.5 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 0.0 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 0.9 | PID_ENDOTHELIN_PATHWAY | Endothelins |
0.0 | 0.9 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 0.7 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.9 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.0 | 0.1 | PID_EPO_PATHWAY | EPO signaling pathway |
0.0 | 0.5 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.9 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.1 | 1.8 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 1.0 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 1.6 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 0.7 | REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS | Genes involved in Recycling of bile acids and salts |
0.0 | 3.2 | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | Genes involved in Extracellular matrix organization |
0.0 | 2.3 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.5 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 0.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.0 | 1.4 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.0 | 0.6 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.0 | 1.2 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.0 | 0.3 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.0 | 0.5 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.4 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.0 | 0.3 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.5 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
0.0 | 0.2 | REACTOME_SIGNALING_BY_FGFR3_MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.0 | 0.5 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 1.1 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.2 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.0 | 0.1 | REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION | Genes involved in Binding and entry of HIV virion |
0.0 | 0.8 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.3 | REACTOME_PD1_SIGNALING | Genes involved in PD-1 signaling |
0.0 | 0.2 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |