Motif ID: CPEB1
Z-value: 0.790
Transcription factors associated with CPEB1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| CPEB1 | ENSG00000214575.5 | CPEB1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CPEB1 | hg19_v2_chr15_-_83240507_83240539 | -0.14 | 5.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 153 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.8 | GO:0070268 | cornification(GO:0070268) |
| 0.1 | 1.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 1.8 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 1.6 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.3 | 1.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.1 | 1.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.1 | 1.3 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.3 | 1.0 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.1 | 1.0 | GO:0016102 | retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) |
| 0.0 | 1.0 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 1.0 | GO:0051602 | response to electrical stimulus(GO:0051602) |
| 0.3 | 0.9 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.3 | 0.9 | GO:0060585 | regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
| 0.1 | 0.9 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.0 | 0.9 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 0.8 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.1 | 0.8 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.1 | 0.8 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
| 0.1 | 0.8 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.1 | 0.8 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 50 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.9 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 1.8 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.3 | 1.5 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 1.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 1.3 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
| 0.0 | 1.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.2 | GO:0000786 | nucleosome(GO:0000786) |
| 0.3 | 1.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.1 | 1.0 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 1.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.2 | 0.9 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.3 | 0.8 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.1 | 0.7 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 0.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.6 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 0.6 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.6 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 77 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 1.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 1.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 1.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 1.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.3 | 1.0 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 1.0 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 1.0 | GO:0019841 | retinol binding(GO:0019841) |
| 0.2 | 0.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.0 | 0.9 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.8 | GO:0042835 | BRE binding(GO:0042835) |
| 0.0 | 0.8 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.7 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.1 | 0.7 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.0 | 0.7 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 0.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 0.6 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.0 | 0.6 | GO:0031489 | myosin V binding(GO:0031489) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 21 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 2.0 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.8 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 1.5 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.0 | 1.1 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.0 | 1.1 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.9 | PID_ENDOTHELIN_PATHWAY | Endothelins |
| 0.0 | 0.9 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.0 | 0.9 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 0.8 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.7 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.7 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.7 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.5 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.5 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.5 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.5 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.5 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.1 | PID_EPO_PATHWAY | EPO signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 28 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.0 | 2.3 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.1 | 1.8 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 1.6 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.4 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 1.2 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 1.1 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 1.0 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 0.9 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.8 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.7 | REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.6 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.5 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 0.5 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.5 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.5 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.4 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
