Motif ID: CTCF_CTCFL

Z-value: 0.891

Transcription factors associated with CTCF_CTCFL:

Gene SymbolEntrez IDGene Name
CTCF ENSG00000102974.10 CTCF
CTCFL ENSG00000124092.8 CTCFL

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CTCFhg19_v2_chr16_+_67596310_675963530.501.3e-02Click!
CTCFLhg19_v2_chr20_-_56100179_561002650.311.4e-01Click!


Activity profile for motif CTCF_CTCFL.

activity profile for motif CTCF_CTCFL


Sorted Z-values histogram for motif CTCF_CTCFL

Sorted Z-values for motif CTCF_CTCFL



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF_CTCFL

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_127615733 2.915 ENST00000373574.1
 WDR38
WD repeat domain 38
chr4_-_7044657 2.746 ENST00000310085.4
 CCDC96
coiled-coil domain containing 96
chr1_-_109655377 2.342 ENST00000369948.3
 C1orf194
chromosome 1 open reading frame 194
chr1_-_109655355 2.301 ENST00000369945.3
 C1orf194
chromosome 1 open reading frame 194
chr11_+_73675873 1.876 ENST00000537753.1
ENST00000542350.1
 DNAJB13

DnaJ (Hsp40) homolog, subfamily B, member 13

chr3_-_167098059 1.861 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
 ZBBX



zinc finger, B-box domain containing



chr6_+_32821924 1.525 ENST00000374859.2
ENST00000453265.2
 PSMB9

proteasome (prosome, macropain) subunit, beta type, 9

chr12_+_82752275 1.466 ENST00000248306.3
 METTL25
methyltransferase like 25
chr22_-_50765489 1.456 ENST00000413817.3
 DENND6B
DENN/MADD domain containing 6B
chr13_+_31774073 1.449 ENST00000343307.4
 B3GALTL
beta 1,3-galactosyltransferase-like
chr17_-_19266045 1.417 ENST00000395616.3
 B9D1
B9 protein domain 1
chr5_+_35617940 1.408 ENST00000282469.6
ENST00000509059.1
ENST00000356031.3
ENST00000510777.1
 SPEF2



sperm flagellar 2



chr4_+_81256871 1.404 ENST00000358105.3
ENST00000508675.1
 C4orf22

chromosome 4 open reading frame 22

chr1_-_40367668 1.386 ENST00000397332.2
ENST00000429311.1
 MYCL

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

chrX_-_117119243 1.346 ENST00000539496.1
ENST00000469946.1
 KLHL13

kelch-like family member 13

chr5_-_118324200 1.297 ENST00000515439.3
ENST00000510708.1
 DTWD2

DTW domain containing 2

chr19_-_48823332 1.289 ENST00000315396.7
 CCDC114
coiled-coil domain containing 114
chr17_+_7591747 1.287 ENST00000534050.1
 WRAP53
WD repeat containing, antisense to TP53
chr17_+_7591639 1.264 ENST00000396463.2
 WRAP53
WD repeat containing, antisense to TP53
chr7_-_123174610 1.112 ENST00000324698.6
ENST00000434450.1
 IQUB

IQ motif and ubiquitin domain containing


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 218 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 2.6 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 2.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 2.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 2.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.3 2.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 2.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 2.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.4 1.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.5 1.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 1.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.3 1.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 1.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 1.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 1.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.3 1.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 1.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 1.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.1 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 1.1 GO:0021762 substantia nigra development(GO:0021762)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0036126 sperm flagellum(GO:0036126)
0.1 2.8 GO:0036038 MKS complex(GO:0036038)
0.1 2.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 2.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 2.2 GO:0097255 R2TP complex(GO:0097255)
0.0 1.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.5 GO:0097433 dense body(GO:0097433)
0.1 1.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.4 GO:0055037 recycling endosome(GO:0055037)
0.1 1.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.1 1.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.0 GO:0030870 Mre11 complex(GO:0030870)
0.3 0.9 GO:0001534 radial spoke(GO:0001534)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 2.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 1.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.1 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 1.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)

Gene overrepresentation in C2:CP category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID_MYC_PATHWAY C-MYC pathway
0.1 1.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.2 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID_IL6_7_PATHWAY IL6-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.0 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 2.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.2 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.0 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.1 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.9 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.9 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.9 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation