Motif ID: DBP

Z-value: 0.590


Transcription factors associated with DBP:

Gene SymbolEntrez IDGene Name
DBP ENSG00000105516.6 DBP

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DBPhg19_v2_chr19_-_49140609_49140643-0.106.4e-01Click!


Activity profile for motif DBP.

activity profile for motif DBP


Sorted Z-values histogram for motif DBP

Sorted Z-values for motif DBP



Network of associatons between targets according to the STRING database.



First level regulatory network of DBP

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_23891693 1.236 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_+_104293028 1.104 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr3_-_112564797 1.085 ENST00000398214.1
ENST00000448932.1
CD200R1L

CD200 receptor 1-like

chr8_+_99076750 1.000 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr2_-_216257849 0.989 ENST00000456923.1
FN1
fibronectin 1
chr10_+_115511213 0.954 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr1_+_104159999 0.941 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr8_+_99076509 0.915 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr15_+_71228826 0.879 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49




leucine rich repeat containing 49




chr1_+_61547405 0.824 ENST00000371189.4
NFIA
nuclear factor I/A
chr9_-_89562104 0.719 ENST00000298743.7
GAS1
growth arrest-specific 1
chrX_-_10851762 0.708 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr13_+_97928395 0.698 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr3_+_141105705 0.683 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr16_+_78056412 0.626 ENST00000299642.4
ENST00000575655.1
CLEC3A

C-type lectin domain family 3, member A

chr3_-_114343768 0.589 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr19_+_13134772 0.572 ENST00000587760.1
ENST00000585575.1
NFIX

nuclear factor I/X (CCAAT-binding transcription factor)

chr15_-_27018175 0.555 ENST00000311550.5
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr5_-_124080203 0.527 ENST00000504926.1
ZNF608
zinc finger protein 608
chr1_-_227505289 0.467 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.4 1.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.3 1.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 0.7 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.3 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0097440 apical dendrite(GO:0097440)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.9 GO:0016160 amylase activity(GO:0016160)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.3 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.1 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors