Motif ID: DLX4_HOXD8

Z-value: 0.821

Transcription factors associated with DLX4_HOXD8:

Gene SymbolEntrez IDGene Name
DLX4 ENSG00000108813.9 DLX4
HOXD8 ENSG00000175879.7 HOXD8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD8hg19_v2_chr2_+_176994408_1769946410.537.3e-03Click!
DLX4hg19_v2_chr17_+_48046538_48046575-0.164.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of DLX4_HOXD8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_16921601 3.782 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3


anterior gradient 3


chr4_-_70518941 2.866 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr4_-_100356291 2.841 ENST00000476959.1
ENST00000482593.1
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr4_-_100356551 2.804 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_52705641 2.784 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr2_+_228736321 2.663 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr4_+_70861647 2.568 ENST00000246895.4
ENST00000381060.2
STATH

statherin

chr21_-_43735628 2.494 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr11_+_27076764 2.381 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_-_71551652 2.278 ENST00000546561.1
TSPAN8
tetraspanin 8
chr12_+_20963647 2.220 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr12_+_20963632 2.193 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr18_-_24722995 1.975 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr4_+_69681710 1.799 ENST00000265403.7
ENST00000458688.2
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr17_+_68071389 1.744 ENST00000283936.1
ENST00000392671.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr2_+_228736335 1.733 ENST00000440997.1
ENST00000545118.1
DAW1

dynein assembly factor with WDR repeat domains 1

chrX_+_119029800 1.707 ENST00000371431.3
ENST00000371423.2
ENST00000371425.4
ENST00000394594.2
AKAP14



A kinase (PRKA) anchor protein 14



chr5_+_140220769 1.670 ENST00000531613.1
ENST00000378123.3
PCDHA8

protocadherin alpha 8

chr6_+_131958436 1.614 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3



ectonucleotide pyrophosphatase/phosphodiesterase 3



chr16_-_28621353 1.600 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_-_25348007 1.554 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1






cancer susceptibility candidate 1






chr11_-_26593779 1.534 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr4_+_69962185 1.523 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr10_-_13043697 1.517 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr12_+_109826524 1.511 ENST00000431443.2
MYO1H
myosin IH
chr22_+_23487513 1.499 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr4_+_69962212 1.493 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr14_-_106926724 1.486 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr12_+_9980113 1.447 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr11_-_102651343 1.425 ENST00000279441.4
ENST00000539681.1
MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr6_-_52668605 1.412 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr2_+_228735763 1.398 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr5_+_140227048 1.364 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr6_+_32407619 1.304 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr19_-_14992264 1.292 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr11_-_26588634 1.290 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chr5_-_35938674 1.278 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr21_+_42694732 1.276 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr2_+_132285406 1.253 ENST00000295171.6
ENST00000409856.3
CCDC74A

coiled-coil domain containing 74A

chr19_-_55677920 1.207 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chr11_+_27015628 1.189 ENST00000318627.2
FIBIN
fin bud initiation factor homolog (zebrafish)
chr11_-_26593649 1.178 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr12_-_91573132 1.177 ENST00000550563.1
ENST00000546370.1
DCN

decorin

chr16_-_28634874 1.174 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr19_-_55677999 1.165 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr6_-_52710893 1.151 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr1_-_183622442 1.142 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr15_-_55657428 1.131 ENST00000568543.1
CCPG1
cell cycle progression 1
chr4_-_38806404 1.125 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr11_-_26593677 1.119 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr5_+_140213815 1.083 ENST00000525929.1
ENST00000378125.3
PCDHA7

protocadherin alpha 7

chr11_+_61976137 1.073 ENST00000244930.4
SCGB2A1
secretoglobin, family 2A, member 1
chr14_+_96949319 1.069 ENST00000554706.1
AK7
adenylate kinase 7
chr12_-_10282836 1.065 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A


C-type lectin domain family 7, member A


chr5_+_140165876 1.058 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr15_-_56757329 1.045 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr13_+_36050881 1.030 ENST00000537702.1
NBEA
neurobeachin
chr5_+_140557371 1.007 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr21_+_25801041 1.001 ENST00000453784.2
ENST00000423581.1
AP000476.1

AP000476.1

chr20_+_31755934 1.000 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr7_-_130080977 0.998 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr3_-_19975665 0.991 ENST00000295824.9
ENST00000389256.4
EFHB

EF-hand domain family, member B

chr6_-_28411241 0.980 ENST00000289788.4
ZSCAN23
zinc finger and SCAN domain containing 23
chr11_+_62104897 0.953 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1


asparaginase like 1


chr19_-_9003586 0.950 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr13_+_50589390 0.940 ENST00000360473.4
ENST00000312942.1
KCNRG

potassium channel regulator

chr10_+_115511213 0.932 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr1_-_60539422 0.923 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr9_+_99690592 0.918 ENST00000354649.3
NUTM2G
NUT family member 2G
chr5_+_156696362 0.913 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr16_+_58283814 0.900 ENST00000443128.2
ENST00000219299.4
CCDC113

coiled-coil domain containing 113

chr6_-_32908792 0.889 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr5_+_121465207 0.878 ENST00000296600.4
ZNF474
zinc finger protein 474
chr3_-_112565703 0.874 ENST00000488794.1
CD200R1L
CD200 receptor 1-like
chr14_+_74486043 0.870 ENST00000464394.1
ENST00000394009.3
CCDC176

coiled-coil domain containing 176

chr5_-_20575959 0.870 ENST00000507958.1
CDH18
cadherin 18, type 2
chr3_+_13610216 0.864 ENST00000492059.1
FBLN2
fibulin 2
chr7_+_99195677 0.852 ENST00000431679.1
GS1-259H13.2
GS1-259H13.2
chr1_+_104159999 0.850 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr1_+_47489240 0.822 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr1_-_36906474 0.821 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr16_+_82068830 0.821 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr11_+_124055923 0.814 ENST00000318666.6
OR10D3
olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chr12_-_71551868 0.803 ENST00000247829.3
TSPAN8
tetraspanin 8
chr1_+_196621156 0.791 ENST00000359637.2
CFH
complement factor H
chr12_-_10151773 0.789 ENST00000298527.6
ENST00000348658.4
CLEC1B

C-type lectin domain family 1, member B

chr5_+_156712372 0.779 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_-_112320749 0.775 ENST00000610103.1
RP11-572C15.6
RP11-572C15.6
chr3_-_197676740 0.775 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
IQCG


IQ motif containing G


chr20_-_3762087 0.768 ENST00000379756.3
SPEF1
sperm flagellar 1
chr14_-_90085458 0.767 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chr12_-_10282681 0.767 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr17_+_68100989 0.757 ENST00000585558.1
ENST00000392670.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr3_-_100712352 0.754 ENST00000471714.1
ENST00000284322.5
ABI3BP

ABI family, member 3 (NESH) binding protein

chr5_-_137475071 0.724 ENST00000265191.2
NME5
NME/NM23 family member 5
chr15_+_50474385 0.722 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr12_-_10282742 0.717 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A


C-type lectin domain family 7, member A


chr11_-_63376013 0.715 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr14_+_22337014 0.715 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr3_-_112564797 0.713 ENST00000398214.1
ENST00000448932.1
CD200R1L

CD200 receptor 1-like

chr6_-_33041378 0.709 ENST00000428995.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr10_-_61900762 0.705 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_51549498 0.702 ENST00000358559.2
ENST00000298239.6
MSMB

microseminoprotein, beta-

chr7_-_122635754 0.695 ENST00000249284.2
TAS2R16
taste receptor, type 2, member 16
chr5_-_110062349 0.695 ENST00000511883.2
ENST00000455884.2
TMEM232

transmembrane protein 232

chr5_-_110062384 0.695 ENST00000429839.2
TMEM232
transmembrane protein 232
chr8_-_133637624 0.695 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr11_-_128894053 0.689 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr12_+_9980069 0.689 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1


killer cell lectin-like receptor subfamily F, member 1


chr14_-_54423529 0.687 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr14_-_107078851 0.687 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr19_-_41356347 0.686 ENST00000301141.5
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr1_+_151682909 0.686 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr4_+_71108300 0.684 ENST00000304954.3
CSN3
casein kappa
chr1_-_89591749 0.681 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr13_+_24144796 0.670 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr1_-_27998689 0.668 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6


interferon, alpha-inducible protein 6


chr12_-_58329819 0.668 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr15_+_71145578 0.667 ENST00000544974.2
ENST00000558546.1
LRRC49

leucine rich repeat containing 49

chr5_-_160279207 0.666 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr12_-_89920030 0.655 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr10_+_7745232 0.655 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr6_+_52442083 0.643 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr1_+_217804661 0.636 ENST00000366933.4
SPATA17
spermatogenesis associated 17
chr21_-_35884573 0.636 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr11_-_49230184 0.633 ENST00000340334.7
ENST00000256999.2
FOLH1

folate hydrolase (prostate-specific membrane antigen) 1

chr6_+_46761118 0.632 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr8_+_40010989 0.629 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr21_-_43735446 0.629 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr3_+_108541545 0.628 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chrX_+_36254051 0.613 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr11_-_59633951 0.608 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr6_+_123038689 0.593 ENST00000354275.2
ENST00000368446.1
PKIB

protein kinase (cAMP-dependent, catalytic) inhibitor beta

chr16_-_28621312 0.590 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_+_25205568 0.590 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr3_+_25831567 0.589 ENST00000280701.3
ENST00000420173.2
OXSM

3-oxoacyl-ACP synthase, mitochondrial

chr12_+_113587558 0.589 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr11_+_71903169 0.588 ENST00000393676.3
FOLR1
folate receptor 1 (adult)
chr6_-_119031228 0.587 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L


centrosomal protein 85kDa-like


chr3_-_114790179 0.586 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_52859046 0.568 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4


glutathione S-transferase alpha 4


chr1_+_85527987 0.568 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63


WD repeat domain 63


chr17_+_68071458 0.567 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_+_148663729 0.563 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr11_-_5255861 0.556 ENST00000380299.3
HBD
hemoglobin, delta
chr14_+_21387491 0.552 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr14_+_22580233 0.552 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chr16_+_77756399 0.552 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7




nudix (nucleoside diphosphate linked moiety X)-type motif 7




chr10_+_53806501 0.551 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chrX_+_55744228 0.549 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr7_-_64023441 0.548 ENST00000309683.6
ZNF680
zinc finger protein 680
chr5_+_175288631 0.547 ENST00000509837.1
CPLX2
complexin 2
chrX_+_55744166 0.541 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr15_+_71228826 0.537 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49




leucine rich repeat containing 49




chr12_+_25205666 0.534 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr4_+_123653807 0.524 ENST00000314218.3
ENST00000542236.1
BBS12

Bardet-Biedl syndrome 12

chr16_+_71560023 0.519 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr19_-_48752812 0.519 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr1_+_196621002 0.519 ENST00000367429.4
ENST00000439155.2
CFH

complement factor H

chr1_-_24741525 0.512 ENST00000374409.1
STPG1
sperm-tail PG-rich repeat containing 1
chr1_+_12806141 0.511 ENST00000288048.5
C1orf158
chromosome 1 open reading frame 158
chr2_+_179318295 0.511 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr19_-_22034809 0.510 ENST00000594012.1
ENST00000595461.1
ENST00000596899.1
ZNF43


zinc finger protein 43


chr4_-_70505358 0.510 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2


UDP glucuronosyltransferase 2 family, polypeptide A2


chr4_-_150736962 0.510 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1


RP11-526A4.1


chr4_+_52917451 0.504 ENST00000295213.4
ENST00000419395.2
SPATA18

spermatogenesis associated 18

chr1_+_160370344 0.499 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr6_+_28092338 0.498 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr11_+_36317830 0.498 ENST00000530639.1
PRR5L
proline rich 5 like
chr4_-_70725856 0.497 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr19_+_15852203 0.496 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr10_+_91152303 0.494 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr4_-_46996424 0.492 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr19_-_48753104 0.489 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr12_+_51318513 0.487 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr11_-_102576537 0.485 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr12_-_89919965 0.485 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr5_+_140248518 0.483 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr7_-_16840820 0.478 ENST00000450569.1
AGR2
anterior gradient 2
chr11_+_73661364 0.475 ENST00000339764.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr2_+_39103103 0.475 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN2




MORN repeat containing 2




chr6_-_110011704 0.467 ENST00000448084.2
AK9
adenylate kinase 9
chr10_+_94594351 0.466 ENST00000371552.4
EXOC6
exocyst complex component 6
chr12_-_63328817 0.461 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr22_-_39190116 0.460 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
SUN2
DNAL4

Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4

chr1_-_60539405 0.460 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr7_+_138943265 0.455 ENST00000483726.1
UBN2
ubinuclein 2
chr5_-_135290705 0.454 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr10_-_118928543 0.454 ENST00000419373.2
RP11-501J20.2
RP11-501J20.2
chr14_+_74035763 0.454 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr3_-_112693759 0.454 ENST00000440122.2
ENST00000490004.1
CD200R1

CD200 receptor 1

chr5_-_41213607 0.452 ENST00000337836.5
ENST00000433294.1
C6

complement component 6

chr11_+_86085778 0.450 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81



coiled-coil domain containing 81



chr1_-_109203997 0.450 ENST00000370032.5
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr11_-_121986923 0.448 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr17_+_72270380 0.446 ENST00000582036.1
ENST00000307504.5
DNAI2

dynein, axonemal, intermediate chain 2

chr15_-_78913628 0.443 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chrX_+_36246735 0.436 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chr13_-_41768654 0.436 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr16_-_28621298 0.434 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 2.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5 1.6 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.4 1.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3 1.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.3 6.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 1.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.7 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 3.8 GO:0009812 flavonoid metabolic process(GO:0009812)
0.2 2.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 1.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.6 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 0.6 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 0.7 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 0.7 GO:0009804 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.2 2.6 GO:0046541 saliva secretion(GO:0046541)
0.2 0.5 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.5 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.3 GO:0050955 thermoception(GO:0050955)
0.1 0.1 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 0.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 1.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.6 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.4 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 2.5 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 1.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 1.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.5 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 3.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 1.0 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0045897 positive regulation of transcription during mitosis(GO:0045897) regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.6 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.5 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 4.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.8 GO:0006824 cobalt ion transport(GO:0006824)
0.1 1.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 2.4 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 1.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.1 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.1 6.0 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 0.4 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.4 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.7 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.2 GO:1900111 regulation of histone H3-K9 dimethylation(GO:1900109) positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 0.2 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.5 GO:2001023 regulation of response to drug(GO:2001023)
0.1 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.2 GO:0052314 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.6 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 2.9 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0090212 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 1.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.4 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.2 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.1 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 1.4 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.2 GO:0003218 cardiac left ventricle formation(GO:0003218) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.1 0.4 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.1 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 5.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.4 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.0 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.0 0.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.4 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.0 7.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0070428 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:2000197 regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0009635 response to herbicide(GO:0009635)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.3 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.3 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.1 GO:1901675 response to methylglyoxal(GO:0051595) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:0030202 negative regulation of cytokine secretion involved in immune response(GO:0002740) heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.6 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:1900133 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.6 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.6 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 2.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.0 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.3 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.5 GO:0002467 germinal center formation(GO:0002467)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0071222 cellular response to biotic stimulus(GO:0071216) cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0060748 paracrine signaling(GO:0038001) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 3.3 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.1 GO:0044782 cilium organization(GO:0044782)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0046606 negative regulation of centrosome cycle(GO:0046606)
0.0 0.5 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.0 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.3 GO:0015866 ADP transport(GO:0015866) ATP transport(GO:0015867)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.1 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0032196 transposition(GO:0032196)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.0 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:2000741 asymmetric neuroblast division(GO:0055059) regulation of mesenchymal stem cell differentiation(GO:2000739) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0065001 negative regulation of histone H3-K36 methylation(GO:0000415) specification of axis polarity(GO:0065001)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0036343 third ventricle development(GO:0021678) psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.1 GO:0072218 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.6 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
0.0 0.0 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.1 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 0.2 GO:0005902 microvillus(GO:0005902)
0.2 1.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0097224 sperm connecting piece(GO:0097224)
0.1 1.0 GO:0002177 manchette(GO:0002177)
0.1 2.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 0.3 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 1.1 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.8 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.1 GO:0043194 axon initial segment(GO:0043194)
0.0 5.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0030424 axon(GO:0030424)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0034358 protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 2.5 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 1.0 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.9 2.7 GO:0046848 hydroxyapatite binding(GO:0046848)
0.7 5.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.6 2.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 1.8 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.4 1.4 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.3 2.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.3 1.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 0.3 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.2 5.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.7 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.8 GO:0016160 amylase activity(GO:0016160)
0.2 0.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 8.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.1 GO:0032089 NACHT domain binding(GO:0032089)
0.2 2.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 4.0 GO:0002162 dystroglycan binding(GO:0002162)
0.2 2.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.6 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 1.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.3 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 1.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 4.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 2.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.6 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.7 GO:0070700 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.1 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.3 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.7 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.6 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.7 GO:0099589 serotonin receptor activity(GO:0099589)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.7 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 1.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.9 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 2.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.0 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 9.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.0 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.1 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.8 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.5 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.4 9.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.3 4.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.2 6.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 4.9 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 6.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.7 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 0.1 REACTOME_GPCR_LIGAND_BINDING Genes involved in GPCR ligand binding
0.1 2.7 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.0 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.1 1.4 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 1.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.9 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME_DEFENSINS Genes involved in Defensins
0.0 0.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.0 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.2 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs