Motif ID: DMBX1

Z-value: 0.256


Transcription factors associated with DMBX1:

Gene SymbolEntrez IDGene Name
DMBX1 ENSG00000197587.6 DMBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DMBX1hg19_v2_chr1_+_46972668_469726690.311.4e-01Click!


Activity profile for motif DMBX1.

activity profile for motif DMBX1


Sorted Z-values histogram for motif DMBX1

Sorted Z-values for motif DMBX1



Network of associatons between targets according to the STRING database.



First level regulatory network of DMBX1

PNG image of the network

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Top targets:


Showing 1 to 20 of 80 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_38859996 0.689 ENST00000264651.2
 KRT24
keratin 24
chr3_+_188664988 0.616 ENST00000433971.1
 TPRG1
tumor protein p63 regulated 1
chr10_+_118187379 0.601 ENST00000369230.3
 PNLIPRP3
pancreatic lipase-related protein 3
chr8_-_125577940 0.510 ENST00000519168.1
ENST00000395508.2
 MTSS1

metastasis suppressor 1

chr2_-_70780572 0.405 ENST00000450929.1
 TGFA
transforming growth factor, alpha
chr18_+_29027696 0.354 ENST00000257189.4
 DSG3
desmoglein 3
chr2_-_70780770 0.313 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
 TGFA


transforming growth factor, alpha


chr19_-_51538118 0.296 ENST00000529888.1
 KLK12
kallikrein-related peptidase 12
chr19_-_51538148 0.294 ENST00000319590.4
ENST00000250351.4
 KLK12

kallikrein-related peptidase 12

chr15_+_93443419 0.234 ENST00000557381.1
ENST00000420239.2
 CHD2

chromodomain helicase DNA binding protein 2

chr6_+_130339710 0.226 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr9_-_21995249 0.221 ENST00000494262.1
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr9_-_21995300 0.213 ENST00000498628.2
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_-_143913143 0.185 ENST00000400889.1
 FAM72D
family with sequence similarity 72, member D
chr1_+_206138457 0.172 ENST00000367128.3
ENST00000431655.2
 FAM72A

family with sequence similarity 72, member A

chr7_+_1727755 0.164 ENST00000424383.2
 ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr1_+_120839005 0.163 ENST00000369390.3
ENST00000452190.1
 FAM72B

family with sequence similarity 72, member B

chr9_-_21994597 0.162 ENST00000579755.1
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr2_+_37571845 0.156 ENST00000537448.1
 QPCT
glutaminyl-peptide cyclotransferase
chr3_-_137851220 0.155 ENST00000236709.3
 A4GNT
alpha-1,4-N-acetylglucosaminyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0070268 cornification(GO:0070268)
0.1 0.7 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular_function category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins